top of page

Search Results

Results found for "Dr. Thomas P. Sakmar"

  • Decoding GPCR Function: The Role of Mutagenesis in Rational Drug Discovery

    -A., Thomas, T., Nguyen, T. D., Muñoz, L. L., Gregory, K. J., White, P. J., Sexton, P.

  • 📰 GPCR Weekly News, July 1 to 7, 2024

    This week's highlight includes congrats to Edda Matthees, Drs.  on GRK specificity and Gβγ dependency determines the potential of a GPCR for arrestin-biased agonism Dr CXV: The Class F of G Protein-Coupled Receptors Yusman Manchanda, Dr. cognate GPCRs and disrupt downstream intracellular signaling Mónica Navarro-Sánchez, Drs. We're thrilled to announce the dates for our upcoming courses led by the renowned Dr.

  • The Truth About GPCR Product Launches: Years in the Making

    Featuring logos from Dr. GPCR and Revvity. In this behind-the-scenes look at the making of Revity’s pHSense, Dr. Dr. Want to hear Dr. Trinquet tell the story in his own words? GPCR   Dr. GPCR X Revvity Collaboration ⸻ Want more like this? 👉 Join the Dr.

  • Signals in Motion: Pain, Metabolism & Terry’s Corner

    Hello GPCR Innovators ,   We’re preparing to launch Terry’s Corner, a new knowledge hub shaped by Dr. Plus, Celtarys explores ligand selection for better assays, and co-founder Dr. pain relief in preclinical models Dr.GPCR Updates Terry’s Corner  – Build Better GPCR Screens with Dr Screening Strategy Leadership in Ligand Design  – The Celtarys Origin Story   In  this founder interview , Dr Best,   The Dr. GPCR Team

  • How to Design GPCR Drugs That Work in Vivo: Strategy, Tools, and Insights

    Week’s GPCR Intelligence: From Set-Point Pharmacology to No-Wash Internalization Assays This week’s Dr Unlock On-Demand Yearly Access Now — Premium Members Get Over 50% Discount at Checkout ➤ Revvity x Dr GPCR: A Mission-Aligned Partnership That Advances the Field At Dr. As Dr. Eric Trinquet shares in a special Dr. I will keep Dr.

  • How Schild Analysis Protects Your Conclusions in GPCR Research

    In this week’s lesson, Dr. Access this week’s key insight ➤ Dr. Dr. 👉 Access this week’s full Premium Edition here ➤ What Members Say “Dr. See you in the Ecosystem, Dr. GPCR Team

  • Assay Volume Control: Your GPCR Drug Discovery Power Lever

    . 🔍 This Week in Dr. In this upcoming episode, Dr. In this behind-the-scenes look, Dr. Read the full story➤ Why Dr. I wish Dr.

  • Biased Agonism at the GLP-1 Receptor: A Pathway to Improved Therapeutic Outcomes

    Nat Rev Drug Discov, 2013. 12 (3): p. 205-16. 2.          Cell Metab, 2018. 27 (4): p. 740-756. 3.          Cell, 2016. 165 (7): p. 1632-1643. 6.          Nat Commun, 2015. 6 : p. 8918. 7.          Endocr Rev, 2023. 44 (3): p. 492-517. 8.         

  • How Understanding Intracellular Drug Access Can Transform Your GPCR Drug Discovery Program

    This week Dr. In this week's Dr. Dr. “The best pharmacology teacher (Dr. Dr.

  • Irreversible Drugs, Real Control: Design for Durable Target Engagement

    This week’s Dr. Emerging Voices in GPCR Biology; Domain Therapeutics patents new PAR2 antagonists. 🔍 This Week in Dr 🎥  Live AMA with Dr. Kenakin — October 30, 12 PM EST   Join Dr. say in the topics covered next Weekly updates that keep your knowledge sharp Monthly live AMAs with Dr Listen to the episode ➤ Why Dr.

  • 📰 GPCR Weekly News, April 29 to May 5, 2024

    Today, we celebrate a huge milestone by releasing Episode #150 of the Dr. GPCR Podcast. ’s episode, so join us in this celebration and be the first to know about all the changes coming to Dr Today is also the first session of our hands-on workshop with Dr. Sam Hoare. If you aren't joining us this time, stay tuned for more Dr. GPCR University content coming soon.

  • How Breakthroughs Happen: Eric Trinquet on Innovation, Serendipity & GPCRs

    Dr. Frame your strategy, then let the serendipity occur.” — Dr. Want to hear Dr. Trinquet tell the story in his own words? Listen to the full podcast episode here ⸻ More about Revvity pHSense Reagents GPCR Reagents Revvity on Dr GPCR   Dr. GPCR X Revvity Collaboration ⸻ Want more like this? 👉 Join the Dr.

  • 📰 GPCR Weekly News, April 1 to 7, 2024

    Dr. GPCR University Hurry! 3 out of the 25 spots have been filled! Join our upcoming Dr. GPCR University hands-on workshop with Dr.  The workshop includes: Four x 2-hour Zoom sessions One-on-one meeting with Dr. Hoare Access to Dr. Dr. Dr.

  • 📰 GPCR Weekly News, January 8 to 14, 2024

    This week's highlight: Dr. Dr. GPCR University February 8 - 29: Join Dr. GPCR University's live course with Dr. Terry Kenakin. GPCR Ecosystem group, where you can find Dr. Kenakin and Dr. GPCR Complimentary one-year Dr. Go to Dr. GPCR University and save your spot today! Dr.

  • 📰 GPCR Weekly News, January 15 to 21, 2024

    This week's highlight: DrDr. GPCR University Our first Dr. Kenakin Access to the cohort’s Dr. Kenakin and Dr. GPCR Complimentary one-year Dr. Dr.

  • Microbial Metabolites Orchestrate a Distinct Multi-Tiered Regulatory Network in the Intestinal Epith

    Expression "P-glycoprotein (P-gp) is a key component of the intestinal epithelium playing a pivotal secondary bile acids, produced by the intestinal microbiome, potentiate the induction of functional P-gp We now aim to determine the molecular mechanism by which this functional microbiome output regulates P-gp combination discovered a unique transcriptional program involving multiple pathways that converge on P-gp on a sophisticated signaling network directed by intestinal microbial metabolites that orchestrate P-gp

  • How to Use Statistical Methods to Strengthen Every GPCR Drug Discovery Decision

    . 🔍 This Week in Dr. This week, Dr. Premium Members get a 50%+ discount when they join Terry’s Corner. 🚨 First-ever Live AMA with Dr. Unlock Terry’s Corner ➤ Dr. GPCR Podcast – Ajay Yekkirala on GPCR Innovation In this episode, Dr. Register now to secure your spot ➤ Why Dr.

  • 📰 GPCR Weekly News, March 25 to March 31, 2024

    GPCR University Get ready for our next Dr. GPCR University hands-on workshop with Dr.  GPCR Ecosystem group, where you can find Dr. Hoare and Dr. GPCR Complementary one-year Dr. Dr. GPCR Symposia With a premium membership, you can watch on-demand the Dr. Dr.

  • GPCR Allostery: Unlock Hidden Mechanisms and Make Smarter Drug Decisions

    Stop Chasing Affinity and Start Reading the System In this week’s cornerstone Terry’s Corner lecture, Dr As the GPCR field surges forward—from ligand bias to signaling diversity—the guest editors Dr. squarely on kinetic modeling, allosteric frameworks, and targeting the “undruggable.” 🔥 Featured:  Dr ” — Dr. GPCR Podcast Listener Why Dr. FAQ: What You Get with Dr. GPCR Premium 🔹 What’s included?

  • Why Kinetics Matter More Than Kd in GPCR Drug Discovery

    Kenakin is a masterful teacher and communicator—and a leading expert in our field.” — Dr. GPCR University Course Attendee Dr. GPCR Podcast : From Personal Pain to Scientific Purpose: Alex Serafini’s Journey We sit down with Dr. Secure your spot ➤ Why Dr. Dr.

  • 📰 GPCR Weekly News, February 19 to 25, 2024

    Isabella Russell, Drs. Dr. Dr. GPCR Partnered Events March 5 - 7, 2024 | 3rd GPCRs - Targeted Drug Discovery Summit. Join Dr. GPCR Founder Dr. Yamina Berchiche at the 3rd GPCRs Summit in Boston on March 5-7, 2024. Dr. April 22 - 23, 2024 | Endocrine Metabolic GPCRs Join Dr. GPCR Founder Dr.

  • 📰 GPCR Weekly News, February 12 to 18, 2024

    This week's highlight includes congrats to Julia Gardner, Dr. Dylan Scott Eiger, Chloe Hicks,  Dr. Drs. Dr. GPCR University The past two weeks of the Dr. Dr. April 22 - 23, 2024 | Endocrine Metabolic GPCRs Join Dr. GPCR founder Dr.

  • 📰 GPCR Weekly News, March 4 to 10, 2024

    Additionally, we are having a Panel Discussion on Publishing in Academia with Drs. Dr. GPCR University Save the date for our upcoming workshop starting May 9th, 2024, featuring Dr. Gain invaluable skills in data analysis under Dr. Hoare's expert guidance. Dr. Terry Kenakin's "Applying Pharmacology to Drug Discovery" course at Dr. Dr.

  • When Pain Becomes a Catalyst: How Personal Experience Redefined One Scientist’s Mission

    For Dr. Alex Serafini, that’s exactly what happened. His new obsession led him to Johns Hopkins, where he worked in the lab of Dr. Dr.

  • 📰 GPCR Weekly News, June 10 to 16, 2024

    This week's highlight includes congrats to: Dr. Levitz for their work on Emerging modes of regulation of neuromodulatory G protein-coupled receptors Dr GPCR University We are thrilled to announce that Dr. Dr. GPCR Podcast Tune into the 156th episode of the Dr. GPCR Podcast, featuring Dr. Post-Doctoral Fellow—Pharmacology/Cell Biology/Biochemistry Post Doctoral Fellow Postdoc Position Join Dr

  • 📰 GPCR Weekly News, May 20 to 26, 2024

    This week's highlight includes congrats to: Cam Sinh Lu, for his first Dr. GPCR University Today marks the final day of the Dr. We're thrilled to announce that Dr. Dr. GPCR Podcast We have thrilling news—Episode 153 of the Dr. GPCR Podcast featuring Dr. Dr.

  • 📰 GPCR Weekly News, January 1 to 7, 2024

    This week's highlights: Congratulations to Drs. Save the dates: February 8 - 29: Join Dr. GPCR University's live Zoom sessions hosted by Dr. GPCR Ecosystem group, where you can find Dr. Kenakin and Dr. GPCR Complimentary one-year Dr. GPCR Ecosystem Premium memberships, a $250 saving Access to Dr.

  • 📰 GPCR Weekly News, April 15 to 21, 2024

    We are pleased to announce five full scholarship opportunities for Dr. Join our upcoming Dr. GPCR University hands-on workshop with Dr.  The workshop includes: Four x 2-hour Zoom sessions One-on-one meeting with Dr. Hoare Access to Dr. Sam Hoare about this hands-on workshop HERE ⬇⬇⬇ Dr. Dr.

  • 📰 GPCR Weekly News, February 26 to March 3, 2024

    This week's highlight includes congrats to: Christina Katharina Kuhn, Drs. Howard Rockman, and Dr.  We are delighted to confirm the participation of esteemed speakers such as DrsDr. GPCR University Great News! The Dr. Dr.

  • 📰 GPCR Weekly News, April 8 to 14, 2024

    Join our upcoming Dr. GPCR University hands-on workshop with Dr.  The workshop includes: Four x 2-hour Zoom sessions One-on-one meeting with Dr. Hoare Access to Dr. We are pleased to announce five full scholarship opportunities for Dr. Check our conversation with Dr. Sam Hoare about this hands-on workshop HERE ⬇⬇⬇ Dr. Dr.

bottom of page