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Rosie Dawaliby "I’m an expert in early-stage drug discovery, targeting membrane proteins, especially In 2016, I joined a company that specialized in therapeutic candidate discovery targeting GPCR ( Confo Therapeutics ) as a team and project leader for antibody discovery for metabolic and inflammatory diseases

interested in using G-Protein Coupled Receptors (GPCRs) that control virtually everything in the body as drug GPCR is to accelerate GPCR drug discovery by sharing the latest research and technology advances in the targets and future drug development. She has made numerous important discoveries related to the mechanisms that control PAR1 signaling and discovery and genomic analysis, delivered technical presentations and software demonstrations to prospective

“I got to know computational chemistry through a project on BCL2 proteins and drug discovery… I was in discovery pipelines. By bridging structural prediction, molecular dynamics, and ligand discovery, his work not only deciphers GPCR ecosystem , GPCR online course , GPCR scientist network , GPCR drug discovery , GPCR training program leveraging computational structure-based tools and develop specific protocols to accelerate OR ligand discovery

Cardarelli is a drug development leader with extensive experience driving drug discovery teams in bringing She oversaw early discovery programs IL-23 p19 and IL23 p19/IL-17 bispecifics. She has extensive experience working with Biologics, and Antibody Drug Conjugates as well as experience

Traditional drug discovery efforts have focused on agonists and antagonists that bind to the orthosteric ubiquitous class of plasma membrane receptors and serve as targets for more than one-third of all prescribed drugs

why visualizing receptor localization and signaling in real tissues is essential for advancing GPCR drug discovery . Why this matters How receptor distribution in islets and brain circuits shapes incretin hormone drug assays Worked across disciplines where chemistry, pharmacology, and physiology converge Questioned how drug

in research are primarily directed towards methods that study GPCRs and GPCR signaling, as well as drug discovery and design."

Our fourth main research aspect is ligand coding mechanisms and structural aided drug discovery of GPCR

start with real-world behavior and models before drilling into GPCR targets — a top-down rethink for drug discovery. << Back to podcast list Dr. “We’re using outdated drugs. There are more elegant GPCR targets waiting to be explored.” He’s fascinated by transgenerational epigenetics — how parental pain, diet, or drug exposure can leave GPCR ecosystem, GPCR drug discovery, GPCR podcast, GPCR data platform, GPCR training program, RGS4, chronic

discovery. How disease can hijack signaling organization — and what that means for drug discovery. In GPCR drug discovery, where complexity is the rule and timelines are tight, this kind of cross-functional an open vault of knowledge. 🟢 Read More → https://www.ecosystem.drgpcr.com/post/accelerating-gpcr-drug-discovery-what Jens Carlsson and his team are redefining what computational modeling means in drug discovery.

cell signaling and GPCRs and made seminal contributions to our understanding of this major class of drug energy transfer (BRET) resulted in the development of screening assays that are now widely used for drug discovery.

His journey highlights the transition from general drug development to a deep dive into G protein-coupled Allosteric Modulation: The New Frontier of GPCR Drug Discovery Ben reflects on the emerging potential Translating Discovery into Therapy: Bench to Bedside Vision Ben’s work seeks to merge in vitro mechanistic “The goal is to smash all the amazing biology together and make a drug.” GPCR ecosystem , GPCR online course , GPCR scientist network , GPCR drug discovery , GPCR training program

Stay at the Forefront of GPCR Drug Discovery Gain insider methods from the pioneers shaping biased signaling discovery Dr. Think of Premium as insurance against wasted experiments and failed drug leads. Aside from his vast experience in drug development, not to mention his extensive publication record, The GPCR Field Is Advancing Fast – Don't Fall Behind Stay ahead in drug discovery with insights from

strengths lie in GPCR signal transduction and neuroscience, and she has expanded it in the areas of drug discovery and structural biology of membrane proteins. has been involved in studying G protein coupled signal transduction for many years and has made key discoveries She has received numerous awards, including the Glaxo Cardiovascular Discovery Award, the Distinguished

This week's GPCR roll-up includes the latest insights, research discoveries, and advancements. Register now and shape the future of drug discovery! and drug discovery Symposium & Workshop - Brazil NEW April 1 - 3, 2025 | 2nd Peptide-Based Therapeutics Discovery Chemistry 2025 - USA April 24 - 27, 2025 | American Physiology Summit 2025 - USA April 25 - 30, 2025 | AACR Annual Meeting 2025 - USA NEW May 1 - 2, 2025 | 5th Ace Drug Discovery Summit 2025

Get guidance, strategies, and insights to optimize your GPCR research and drug discovery projects. Power My Discovery Biotech Clients Want Results - Not Confusion Every CRO I work with has great science—but Any CRO focused on GPCRs, pharmacology, discovery biology, or antibody discovery—regardless of size or Power My Discovery Send me a message First name* Last name Company name* Email* How Can I Help? Let’s talk about how I support GPCR discovery, pharmacology strategy, and cross-functional execution

expert guidance, vetted CROs, and data-driven strategies to invest smarter and move faster in GPCR drug discovery. Fast Track My Discovery The wrong CRO—or wrong experiments—can burn months and millions You're not here Chat about My Discovery Send me a message First name* Last name Company name* Email* How Can I Help? Let’s talk about how I support GPCR discovery, pharmacology strategy, and cross-functional execution

GPCR Podcast Strategic Partners Xylazine, Fentanyl, and the Fight for Breath with Catherine Demery Two drugs path—industry chemist, NIH researcher, and now GPCR pharmacologist—led her to investigate how these drugs Who Should Listen This episode is especially relevant for: GPCR drug discovery scientists Respiratory master’s in pharmacogenomics at Manchester University, igniting her fascination with how genetics and drugs

partner, you'll gain trusted access to an engaged audience of academic researchers, biotech teams, and drug discovery innovators—without having to fight for attention. GPCR platform as a valued partner ✓ Share insights on product launches, scientific discoveries, or customer

strategic decisions that shaped these tools—and why reliable chemical probes are transforming GPCR drug discovery . Rate on Spotify ✉️ Send feedback to the team Recent Podcast Articles How Collaboration Drives GPCR Discoveries How a Failed Experiment Created a Powerful GPCR Imaging Tool From Farm Fields to GPCR Discovery, GLP

His passion lies in turning cutting-edge probe chemistry into robust, scalable tools for drug discovery

global leader in life science innovation, delivering tools and technologies that bridge the gap between discovery unwavering focus on precision, Revvity empowers scientists to simplify complex workflows, accelerate discovery designing the next generation of therapeutics, Revvity isn’t just a provider—they’re your partner in discovery GPCR, the global nonprofit platform dedicated to advancing GPCR research and drug discovery, is proud Learn how pH Sense changes the game for drug discovery. Dr. GPCR Podcast Sep 26 3 min read Dr.

Karine Pichavant , I contributed to the development of a drug to treat hypovolemic shock after severe Cone was the first to clone the melanocortin receptors (the GPCRs that led to the discovery of MRAP2) In-vivo techniques, I adapted my arrestin recruitment assay to a high throughput screening format for drug discovery, I have started molecular work on the melanocortin receptors.

Anaesthesiology and Intensive Care, Medical Faculty, Leipzig University, Leipzig, Germany 5 Institute for Drug Discovery, Faculty of Medicine, Leipzig University 6 School of Medicine, University of Global Health

target discovery. for the culture of normal and malignant pancreatic tissue, allowing advances in sequencing, target discovery Scientific Journey and Drug Discovery Challenges Mike shared significant moments in his scientific journey , including the discovery of RGS proteins and its impact on his research approach. He also discussed his experiments and discoveries about GPR161 in mammary epithelial cells, the effect

. 🔬 Drive discoveries. scientists worldwide, where collaboration fuels innovation and every voice helps shape the future of discovery Explore 200+ expert talks that bring GPCR discoveries to life From structural biology to therapeutics every scientist needs to see pharmacology clearly, from core principles to the hidden variables of drug discovery projects.

Share our ecosystem, courses, and events to advance drug discovery together. Dr.

discovery. They also explored the significance of translating fundamental discoveries into clinical applications Translating Discovery Into Clinical Application Arthur and Yamina discussed the importance of translating fundamental discoveries into clinical applications in their research, highlighting the unique opportunities They also emphasized the significance of fundamental discoveries, the role of biotech, and the need for

discovery. They also explored the significance of translating fundamental discoveries into clinical applications Translating Discovery Into Clinical Application Arthur and Yamina discussed the importance of translating fundamental discoveries into clinical applications in their research, highlighting the unique opportunities They also emphasized the significance of fundamental discoveries, the role of biotech, and the need for

. 🗓️ Upcoming 4-Week Course: Development of GPCR Ligands as Therapeutic Drugs starting March 20 – April sessions, you'll dive into: Advanced pharmacokinetic modeling The Druglike Quality of Chemical Entities Drug discovery: Cell-based assays for GLP-1 and the G-Suite March 17 - 21, 2025 | 2nd GPCR signaling and drug discovery Symposium & Workshop NEW April 2 - 3, 2025 | New therapeutic modalities: Transforming Discovery Summit June 22 - 26, 2025 | G Protein-coupled Receptor Kinases and Arrestins NEW December