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Every week, we send you the most relevant news, research, and advancements in the field. For Dr. kidney disease GPCRs in Oncology and Immunology Purinergic GPCR-integrin interactions drive pancreatic cancer Methods & Updates in GPCR Research The application of targeted protein degradation technologies to G

GPCR at the Endocrine Metabolic GPCRs Summit on April 22-23, 2024, in Birmingham, UK. Dr. receptor 141 expressed in myeloid cells functions as an inflammation suppressor Methods & Updates in GPCR Research Jude Children’s Research Hospital adds $13 million project to Research Collaboratives Program AIRSUPRA 20th World Congress of Basic and Clinical Pharmacology 2026 GPCR Jobs NEW Post-Doc position NEW Lead Researcher Senior Researcher in Structural Biology Post-Doctoral Fellow Postdoctoral Fellow Research Laboratory

Their method allows researchers to explore different linker positions, tailor activity (agonist or antagonist Maria emphasizes the importance of genuinely listening to researchers: understanding the biological question GPCR ecosystem , Celtarys is opening up that model to the broader research community. The goal? ______________ Keyword Cloud:   GPCR data platform , fluorescent ligands , assay development , GPCR research

co-founders soon realized, commercializing it was the only way to deliver that value to the broader GPCR research Celtarys Research, now partnering with Dr. GPCR, is helping researchers worldwide gain access to customized, reliable assay tools without the delays science-driven solutions on their company page . _______________ Keyword Cloud:   GPCR drug discovery , GPCR research

GPCRs in Oncology and Immunology Pan-cancer functional analysis of somatic mutations in G protein-coupled Methods & Updates in GPCR Research 3,4-Bis(hydroxymethyl)hexane-1,6-diol-based Maltosides (HDMs) for

exceptional professors' ability to simplify the complexity of GPCR pharmacology and apply it to their research Regulating Hunger and Satiety OMass Therapeutics Expands Development Team with Key Appointments in US and UK Europe July 12 - 17, 2026 | 20th World Congress of Basic and Clinical Pharmacology GPCR Jobs HIGHLIGHT Research Scientist, Computational Chemistry Postdoc in GPCR mechanosensing   Postdoctoral Position Postdoctoral research protein coupled receptor transcripts in human immune cells and platelets Methods & Updates in GPCR Research

engineered a third path : a partnership between BMS and UConn that allowed him to do industry-based research How It Worked BMS funded the research, salary, and even tuition UConn accepted the research done in the BMS lab as part of the dissertation Sokhom met weekly with advisors and monthly for presentations All research

opportunities:  Senior/Principal Scientist—GPCR Pharmacology; Principal Scientist—In Vitro Pharmacology; Research Johannes Broichhagen Reliable imaging tools change how researchers see receptor behavior. This feature from Celtarys Research outlines how to structure an HCS workflow that avoids batch effects It’s a system-aware resource built for researchers who need clarity fast—reinforcing system-level GPCR Weekly research, careers, and industry intelligence; GPCR University; 200+ expert talks; networking;

Small-molecule targeting of GPCR-independent non-canonical G protein signaling inhibits cancer progression Methods & Updates in GPCR Research GPCRLigNet: rapid screening for GPCR active ligands using machine Bioinformatics/Data Science at Department of Drug Design and Pharmacology Scientist/Senior Scientist (Research

In research, including the GPCR world collaboration isn’t a luxury. It’s survival. The GPCR Collaboration Mindset Behind Breakthrough Science Most researchers have a story about the moment And some simply misled entire research programs. The result was a set of chemical probes that finally allowed researchers to visualize where receptors The Future of GPCR Collaboration in Metabolic Research The next decade of metabolic research won’t hinge

From Patient to Researcher Alex wasn’t always planning to be a scientist. changed when his recurring pain — and the rigid protocols around opioid prescription — forced him to search school, Serafini aims to follow the physician-scientist path: part-time clinical work, mostly lab-based research journey proves how personal pain can lead to professional purpose — and why the next generation of pain researchers needs to start from lived experience, not just literature. _________________ Keyword Cloud: GPCR research

Our access program for researchers in developing countries  continues as well: eligible scientists can They go beyond sponsorship to bring tools and technologies directly to the researchers who use them , Our partnerships with Celtarys Research  and Revvity are great examples — uniting innovation and application to advance GPCR research worldwide. a global platform dedicated to connecting GPCR scientists, industry experts, and innovators through research

focused on orally administered therapeutics to treat autoimmune diseases, inflammatory disorders and cancer

intertwining roles of caveolin, oxytocin receptor, and the associated signalling pathways in prostate cancer November 2 - 4, 2023) GPCR Jobs NEW Associate Director / Director, Clinical Operations Postdoctoral Research

When Sokhom joined Alkermes, the company had a strong development arm, but a relatively underdeveloped research In a field like GPCR research (where data complexity and failure rates are high), scientific rigor thrives GPCR ecosystem , GPCR research community , GPCR podcast , GPCR data platform , GPCR training program

Meanwhile, researchers in the building across the way turned off the lights at 6 PM. Hodson made what seemed like a purely tactical decision: choose a research elective to focus on exams That choice led him to immunology research on pigs — and, eventually, to a PhD. That partnership eventually produced fluorescent GPCR tools  that allow researchers to visualize GPCR differently in different patients These tools have now been shared with hundreds of labs , accelerating research

At one point, he even questioned whether research was the right career for him. Still, early research internships were rocky. Discovering Modeling (and GPCRs) by Accident That interest led him to pursue a thesis at Scripps Research For Carlsson, this marked a shift in how his lab approached GPCR research. He came to see that effective GPCR research requires true interdisciplinary integration.

Yamina Berchiche at the Endocrine Metabolic GPCRs event in Birmingham, UK, on April 22-23, 2024. migration of human T cells by directing GPCR and lipid second messenger signaling Methods & Updates in GPCR Research Congress of Basic and Clinical Pharmacology 2026 GPCR Jobs NEW Senior Scientist- Internal Medicine Research NEW Postdoctoral Scholar – Synaptic physiology, optical imaging, substance use disorder, pharmacology Research - Single-molecule Imaging Center Scientific Assistant Postdoctoral Fellowship- Mechanistic Biology Research

, This week's breakthroughs are crucial for staying ahead in the rapidly evolving landscape of GPCR research Career opportunities:  Explore a selection of high-level job openings in high-throughput screening, research Catherine’s research, blending GPCR signaling studies with public health data, offers critical insights Competitive Edge:  Stay informed on emerging public health threats and the scientific research aimed Shape the next generation of cellular biochemistry research.

multiple roles in the pathological mechanisms of a wide range of diseases including heart failure, cancer

The research team, led by Brandon Novy and colleagues, utilized an innovative APEX2/AUR biosensor that By employing this biosensor, the research team identified 492 genes that significantly influence DOR After the labeling reaction, the researchers purified and biotinylated proteins (those that have been As the opioid crisis continues to challenge public health, insights gained from this research could inform The implications of this research extend beyond basic science ; understanding the role of DNAJC13 in

transmitting signals from the outside into the cells, making them an essential target in biomedical research PerkinElmer High Content Analysis System Operetta CLS used by a Celtarys Research coworker. Exploring the Applications of Confocal Fluorescence Microscopy in GPCR Research In GPCR research one Fluorescence Microscopy validation performed in the ONCOMET laboratory (Health Research Institute of

For most researchers, that’s a dead end. For Alessandro Nicoli, it’s an opportunity. —Alessandro Nicoli For the first time, researchers had a reliable set of predicted structures to work —Alessandro Nicoli A New Era of GPCR Research AlphaFold didn’t just fill a gap—it shifted the focus of

GPCR targets and advance the development of new gastrointestinal therapeutics Tokyo, Japan, Cambridge, UK City-based Kallyope, pioneers in drug discovery involving the gut-brain axis, have entered a strategic research

For instance, aberrant endosomal signaling by GPCRs has been linked to disorders such as cancer, neurodegenerative Neurochemical research, 42(1), 166–172. https://doi.org/10.1007/s11064-016-2026-6 Mendizabal-Zubiaga, GPCRomics: GPCR Expression in Cancer Cells and Tumors Identifies New, Potential Biomarkers and Therapeutic

of Heydenreich et al. (2023) will be analysed to demonstrate how mutagenesis can be employed in GPCR research Through an in-depth mutational analysis of β2AR, the researchers identified specific residues that influence This case study underscores the critical importance of mutagenesis in GPCR research. Rational Drug Design One immediate application of this research lies in rational drug design . By identifying key β2AR residues that influence efficacy and potency, pharmaceutical researchers can

has been implicated in a range of diseases, including cardiovascular disease, pain, hypertension, and cancer While in cancer, RGS proteins are involved in regulating cell proliferation and survival[8]. al., Identification of a five-gene signature of the RGS gene family with prognostic value in ovarian cancer

Check out our latest coverage of GPCRs this week, featuring 15 insightful research papers and industry Stay informed with the latest GPCR research and industry news. Nicola J Smith, Lauren T May, and Natasha L Grimsey for their work on Highlights and hot topics in GPCR research Join the global GPCR community and share your research—submit your abstract using this form. Technologies Novo Nordisk Scientist I - Global Research Technologies Novo Nordisk Join Dr.

environment, paired with a supportive supervisor, laid the foundation for a fulfilling and productive research Supervisors not only guide your research but also shape your academic and professional growth. These mini "journal clubs" kept me informed about the latest research and sharpened my critical thinking choose a lab and mentor that align with your values and goals, embrace the discipline of structured research challenges will test your resolve, but every small victory along the way shapes you into a stronger researcher

A Career Built on Consistency From CGRP receptor antagonists at BMS to opioid receptor research at Alkermes drug discovery , G protein-coupled receptors , GPCR webinar series , GPCR scientist network , GPCR research