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  • 📰 GPCR Weekly News, April 17 to 23, 2023

    👋 Take a look at the latest and greatest in GPCR research. Methods & Updates in GPCR Research Solvent accessibility of a GPCR transmembrane domain probed by in-membrane Sosei Heptares presented novel Computational Chemistry and Cheminformatics approaches for GPCR SBDD at UK - Senior Scientist, Cell-Based Assay Development Post Doctoral Fellow Research associate in protein production Vice President, Oncology Clinical Research Explore Dr.

  • Why Kinetics Matter More Than Kd in GPCR Drug Discovery

    ahead without noise or delays: Industry insights:  Structure-Based Drug Design Summit; AI-Powered GPCR Research Upcoming events:  5th MMCS New Trends in Drug Discovery; GPCR-UK Network Meeting; neuroGPCR Symposium unconventional path—from patient to scientist—exemplifies why personal mission matters in translational research Redefine your playbook:  Why Serafini believes that pain research needs to start from clinical phenotype s Corner  digital pharmacology courses Priority access to insights from major conferences, emerging research

  • 📰 GPCR Weekly News, March 20 to 26, 2023

    Every week, we send you the most relevant news, research, and advancements in the field. For Dr. kidney disease GPCRs in Oncology and Immunology Purinergic GPCR-integrin interactions drive pancreatic cancer Methods & Updates in GPCR Research The application of targeted protein degradation technologies to G

  • 📰 GPCR Weekly News, January 15 to 21, 2024

    GPCR at the Endocrine Metabolic GPCRs Summit on April 22-23, 2024, in Birmingham, UK. Dr. receptor 141 expressed in myeloid cells functions as an inflammation suppressor Methods & Updates in GPCR Research Jude Children’s Research Hospital adds $13 million project to Research Collaboratives Program AIRSUPRA 20th World Congress of Basic and Clinical Pharmacology 2026 GPCR Jobs NEW Post-Doc position NEW Lead Researcher Senior Researcher in Structural Biology Post-Doctoral Fellow Postdoctoral Fellow Research Laboratory

  • Beyond the Probe: Scaling Innovation From the Bench to Product Launch

    Their method allows researchers to explore different linker positions, tailor activity (agonist or antagonist Maria emphasizes the importance of genuinely listening to researchers: understanding the biological question GPCR ecosystem , Celtarys is opening up that model to the broader research community. The goal? ______________ Keyword Cloud:   GPCR data platform , fluorescent ligands , assay development , GPCR research

  • Dr. GPCR and Eurofins DiscoverX Join Forces to Accelerate GPCR Drug Discovery

    GPCR , the global knowledge hub for G protein-coupled receptor (GPCR) research and education, today announced This partnership is designed to support the GPCR research community by expanding access to validated, assays—they build true scientific partnerships that help teams get the most from their data and advance GPCR research we look forward to sharing scientific insight, best practices, and real-world applications that help researchers cell-based assay technologies, providing industry-standard, regulatory-accepted platforms spanning basic research

  • From Lab Bench to Boardroom: The Unexpected Path of a Medicinal Chemist

    co-founders soon realized, commercializing it was the only way to deliver that value to the broader GPCR research Celtarys Research, now partnering with Dr. GPCR, is helping researchers worldwide gain access to customized, reliable assay tools without the delays science-driven solutions on their company page . _______________ Keyword Cloud:   GPCR drug discovery , GPCR research

  • 📰 GPCR Weekly News

    GPCRs in Oncology and Immunology Pan-cancer functional analysis of somatic mutations in G protein-coupled Methods & Updates in GPCR Research 3,4-Bis(hydroxymethyl)hexane-1,6-diol-based Maltosides (HDMs) for

  • GPCR Buzz of the Week | Sep 23 - 29, 2024

    exceptional professors' ability to simplify the complexity of GPCR pharmacology and apply it to their research Regulating Hunger and Satiety OMass Therapeutics Expands Development Team with Key Appointments in US and UK Europe July 12 - 17, 2026 | 20th World Congress of Basic and Clinical Pharmacology GPCR Jobs HIGHLIGHT Research Scientist, Computational Chemistry Postdoc in GPCR mechanosensing   Postdoctoral Position Postdoctoral research protein coupled receptor transcripts in human immune cells and platelets Methods & Updates in GPCR Research

  • From Technician to Trailblazer: How Sokhom Pin Designed His Own PhD Program While Working in Industry

    engineered a third path : a partnership between BMS and UConn that allowed him to do industry-based research How It Worked BMS funded the research, salary, and even tuition UConn accepted the research done in the BMS lab as part of the dissertation Sokhom met weekly with advisors and monthly for presentations All research

  • How System-Level GPCR Thinking Prevents Discovery Failures

    opportunities:  Senior/Principal Scientist—GPCR Pharmacology; Principal Scientist—In Vitro Pharmacology; Research Johannes Broichhagen Reliable imaging tools change how researchers see receptor behavior. This feature from Celtarys Research outlines how to structure an HCS workflow that avoids batch effects It’s a system-aware resource built for researchers who need clarity fast—reinforcing system-level GPCR Weekly research, careers, and industry intelligence; GPCR University; 200+ expert talks; networking;

  • 📰 GPCR Weekly News, February 20 to 26, 2023

    Small-molecule targeting of GPCR-independent non-canonical G protein signaling inhibits cancer progression Methods & Updates in GPCR Research GPCRLigNet: rapid screening for GPCR active ligands using machine Bioinformatics/Data Science at Department of Drug Design and Pharmacology Scientist/Senior Scientist (Research

  • How Collaboration Drives GPCR Discoveries

    In research, including the GPCR world collaboration isn’t a luxury. It’s survival. The GPCR Collaboration Mindset Behind Breakthrough Science Most researchers have a story about the moment And some simply misled entire research programs. The result was a set of chemical probes that finally allowed researchers to visualize where receptors The Future of GPCR Collaboration in Metabolic Research The next decade of metabolic research won’t hinge

  • When Pain Becomes a Catalyst: How Personal Experience Redefined One Scientist’s Mission

    From Patient to Researcher Alex wasn’t always planning to be a scientist. changed when his recurring pain — and the rigid protocols around opioid prescription — forced him to search school, Serafini aims to follow the physician-scientist path: part-time clinical work, mostly lab-based research journey proves how personal pain can lead to professional purpose — and why the next generation of pain researchers needs to start from lived experience, not just literature. _________________ Keyword Cloud: GPCR research

  • A Note from Yamina: Building the Next Chapter of Dr. GPCR

    Our access program for researchers in developing countries  continues as well: eligible scientists can They go beyond sponsorship to bring tools and technologies directly to the researchers who use them , Our partnerships with Celtarys Research  and Revvity are great examples — uniting innovation and application to advance GPCR research worldwide. a global platform dedicated to connecting GPCR scientists, industry experts, and innovators through research

  • Amgen to Acquire Chemocentryx for $4 Billion in Cash

    focused on orally administered therapeutics to treat autoimmune diseases, inflammatory disorders and cancer

  • 📰 GPCR Weekly News, May 22 to 28, 2023

    intertwining roles of caveolin, oxytocin receptor, and the associated signalling pathways in prostate cancer November 2 - 4, 2023) GPCR Jobs NEW Associate Director / Director, Clinical Operations Postdoctoral Research

  • Lab Leadership Without Ego: How Sokhom Pin Built the Happiest Team at Alkermes

    When Sokhom joined Alkermes, the company had a strong development arm, but a relatively underdeveloped research In a field like GPCR research (where data complexity and failure rates are high), scientific rigor thrives GPCR ecosystem , GPCR research community , GPCR podcast , GPCR data platform , GPCR training program

  • From Farm Fields to GPCR Discovery, GLP-1 and GIP

    Meanwhile, researchers in the building across the way turned off the lights at 6 PM. Hodson made what seemed like a purely tactical decision: choose a research elective to focus on exams That choice led him to immunology research on pigs — and, eventually, to a PhD. That partnership eventually produced fluorescent GPCR tools  that allow researchers to visualize GPCR differently in different patients These tools have now been shared with hundreds of labs , accelerating research

  • From Failed Experiments to Predictive GPCR Models

    At one point, he even questioned whether research was the right career for him. Still, early research internships were rocky. Discovering Modeling (and GPCRs) by Accident That interest led him to pursue a thesis at Scripps Research For Carlsson, this marked a shift in how his lab approached GPCR research. He came to see that effective GPCR research requires true interdisciplinary integration.

  • Inside the New Dr. GPCR Ecosystem: Learning, Insight, and Momentum for 2026

    If you’ve felt the pace of GPCR research accelerating—and the signal getting harder to separate from Career opportunities:  In vitro Pharmacology Research Assistant—Geneva. drug hunters, and decision-makers stay grounded in fundamentals while keeping pace with modern GPCR research inputs, members get a coherent view of the GPCR landscape—connecting fundamentals to application, and research Premium Edition here ➤ From the Community “Great initiative—clear guidance on career paths, choosing research

  • 📰 GPCR Weekly News, February 19 to 25, 2024

    Yamina Berchiche at the Endocrine Metabolic GPCRs event in Birmingham, UK, on April 22-23, 2024. migration of human T cells by directing GPCR and lipid second messenger signaling Methods & Updates in GPCR Research Congress of Basic and Clinical Pharmacology 2026 GPCR Jobs NEW Senior Scientist- Internal Medicine Research NEW Postdoctoral Scholar – Synaptic physiology, optical imaging, substance use disorder, pharmacology Research - Single-molecule Imaging Center Scientific Assistant Postdoctoral Fellowship- Mechanistic Biology Research

  • The Hidden Driver of GPCR Drug Success: Why Target Residence Time Matters More Than You Think

    , This week's breakthroughs are crucial for staying ahead in the rapidly evolving landscape of GPCR research Career opportunities:  Explore a selection of high-level job openings in high-throughput screening, research Catherine’s research, blending GPCR signaling studies with public health data, offers critical insights Competitive Edge:  Stay informed on emerging public health threats and the scientific research aimed Shape the next generation of cellular biochemistry research.

  • Applications of Fluorescent Probes in Confocal Imaging of GPCRs: From Live to Fixed Cells

    transmitting signals from the outside into the cells, making them an essential target in biomedical research PerkinElmer High Content Analysis System Operetta CLS used by a Celtarys Research coworker. Exploring the Applications of Confocal Fluorescence Microscopy in GPCR Research In GPCR research one Fluorescence Microscopy validation performed in the ONCOMET laboratory (Health Research Institute of

  • G protein-coupled receptor kinase type 2 and β-arrestin2: Key players in immune cell functions...

    multiple roles in the pathological mechanisms of a wide range of diseases including heart failure, cancer

  • APEX2/AUR Biosensor: A Powerful Tool for Protein Interaction and Trafficking

    The research team, led by Brandon Novy and colleagues, utilized an innovative APEX2/AUR biosensor that By employing this biosensor, the research team identified 492 genes that significantly influence DOR After the labeling reaction, the researchers purified and biotinylated proteins (those that have been As the opioid crisis continues to challenge public health, insights gained from this research could inform The implications of this research extend beyond basic science ; understanding the role of DNAJC13 in

  • Decoding Olfactory GPCRs: How AlphaFold and AI Are Changing the Game

    For most researchers, that’s a dead end. For Alessandro Nicoli, it’s an opportunity. —Alessandro Nicoli For the first time, researchers had a reliable set of predicted structures to work —Alessandro Nicoli A New Era of GPCR Research AlphaFold didn’t just fill a gap—it shifted the focus of

  • An overview of the compartmentalized GPCR Signaling: Relevance and Implications

    For instance, aberrant endosomal signaling by GPCRs has been linked to disorders such as cancer, neurodegenerative Neurochemical research, 42(1), 166–172. https://doi.org/10.1007/s11064-016-2026-6 Mendizabal-Zubiaga, GPCRomics: GPCR Expression in Cancer Cells and Tumors Identifies New, Potential Biomarkers and Therapeutic

  • Regulators of G-protein signaling: essential players in GPCR signaling

    has been implicated in a range of diseases, including cardiovascular disease, pain, hypertension, and cancer While in cancer, RGS proteins are involved in regulating cell proliferation and survival[8]. al., Identification of a five-gene signature of the RGS gene family with prognostic value in ovarian cancer

  • Sosei Heptares and Kallyope Enter Collaboration to Identify and Validate Novel Gastrointestinal GPCR

    GPCR targets and advance the development of new gastrointestinal therapeutics Tokyo, Japan, Cambridge, UK City-based Kallyope, pioneers in drug discovery involving the gut-brain axis, have entered a strategic research

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