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Results found for "GPCR data platform"

  • 📰 GPCR Weekly News, July 3 to 9, 2023

    Hello GPCR enthusiasts! We're here to share the latest GPCR news with you. Congratulations to Dr. GPCR Symposium on Structural and Molecular Insights on GPCR Activation is quickly approaching! GPCR Newsletter for updates! a polyvalent cell-based high-throughput platform. GPCR Ecosystem

  • 📰 GPCR Weekly News, October 30 to November 4, 2023

    Good day, GPCR folks! Take advantage of our GPCR highlights of the week. Dr. GPR3: Save the dates: November 17: Join our final Dr. GPCR Symposium for the year on GPCRs in Immunology and Oncology! Medal in 2023 'This field is in its infancy': Amgen noncommittal on oral obesity med until phase 1 data GPCR Ecosystem

  • 📰 GPCR Weekly News, July 10 to 16, 2023

    Welcome, GPCR enthusiasts! This week's GPCR papers feature a publication by Dr. Robert J Lefkowitz. GPCR Symposium on Structural and Molecular Insights on GPCR Activation! GPCR Newsletter for updates! Hijacking of GPCRs and RTKs by pathogens. GPCR Ecosystem

  • Sosei Heptares and Kallyope Enter Collaboration to Identify and Validate Novel Gastrointestinal GPCR

    2022 Sosei Heptares and Kallyope Enter Collaboration to Identify and Validate Novel Gastrointestinal GPCR unique and valuable access to the Sosei Heptares compound library for its industry-leading biology platform to identify potential GPCR targets and advance the development of new gastrointestinal therapeutics entered a strategic research collaboration to identify and validate novel G protein-coupled receptor (GPCR drug discovery programs in the area of gastrointestinal diseases. " Read more at the source #DrGPCR #GPCR

  • 📰 GPCR Weekly News, June 12 to 18, 2023

    Greetings GPCR enthusiasts! Join us to explore the fascinating world of GPCRs. we delve into the latest news, we'd like to highlight some upcoming events and resources: Save the date GPCR Symposium on Structural and Molecular Insights on GPCR Activation. , CTO of Exscientia discuss transforming drug discovery using their AI-driven platform Salipro Biotech GPCR Ecosystem

  • Phosphorylation of RGS regulates MAP kinase localization and promotes completion of cytokinesis

    These data lead us to a model where Kel1 promotes completion of cytokinesis before pheromone-induced Read more at the source #DrGPCR #GPCR #IndustryNews

  • The Gluopsins: Opsins without the Retinal Binding Lysine

    Our final opsin phylogeny is the largest to date with 4956 opsins. Read more at the source #DrGPCR #GPCR #IndustryNews Subscribe to the Newsletter HERE

  • 📰 GPCR Weekly News, April 17 to 23, 2023

    This week's GPCR papers feature authors such as Drs. Save the date! Dr. GPCR Symposium on GPCR Activation and Signaling, May 19th, 2023. Methods & Updates in GPCR Research Solvent accessibility of a GPCR transmembrane domain probed by in-membrane Industry News Data Presented at AACR 2023 Highlights Exscientia’s Clinical and Preclinical Development GPCR Ecosystem

  • 📰 GPCR Weekly News, June 5 to 11, 2023

    Hi there GPCR enthusiasts! Join us this week for a deep dive into the world of GPCRs. GPCR Symposium on Structural and Molecular Insights on GPCR Activation. Adhesion GPCRs Collagen VI Is a Gi-Biased Ligand of the Adhesion GPCR GPR126/ADGRG6. GPCRs in Immunology and Oncology The GPCR–Gαs–PKA signaling axis promotes T cell dysfunction and cancer GPCR Ecosystem

  • 📰 GPCR Weekly News, November 6 to November 12, 2023

    This week, we've curated 12 GPCR papers. Save the date: TOMORROW - November 17: Don't miss out on our final Dr. GPCR Symposium for the year, which will focus on GPCRs in Immunology and Oncology. for high-throughput gpcrs antibody discovery Reviews, GPCRs, and more Current strategic trends in drug GPCR Ecosystem

  • Molecular insights into regulation of constitutive activity by RNA editing 5HT2C serotonin receptor

    network located on intracellular loop 2 that is subject to RNA editing, which differentially affects GPCR Read more at the source #DrGPCR #GPCR #IndustryNews

  • Lack of Oestrogen Receptor Expression in Breast Cancer Cells Does Not Correlate with Kisspeptin...

    Overall, our data shows that, in TNBC, it is not universally true that kisspeptin/KISS1R stimulate migration Read more at the source #DrGPCR #GPCR #IndustryNews

  • Breaking the Myth of High and Low Affinity Sites

    cutting-edge insights that help you move beyond outdated assumptions and equip your team to interpret data The interpretation of high and low affinity binding sites  on GPCRs.   Access Immediate, Actionable Insight   You’ll gain the insight needed to:   Interpret complex binding data Unlock “Rethinking Affinity” Now Only in Terry's Corner _____ #GPCR #BindingAffinity #Pharmacology

  • 📰 GPCR Weekly News, July 31 to August 6, 2023

    Greetings, GPCR fellows! Prepare for the latest GPCR updates. This week's highlights: Dr. Adhesion GPCRs Functional partnerships between GPI-anchored proteins and adhesion GPCRs GPCR Activation in physiology - many functions in many tissues Bispecific Monoclonal Antibodies in Multiple Myeloma: Data NEW Research Scientist/Senior Scientist I - Molecular Pharmacology NEW Director, Clinical Data Management GPCR Ecosystem

  • Fluorescence based HTS compatible ligand binding assays for dopamine D3 receptors in baculovirus preparations and live cells

    Introduction Dopamine receptors are G-protein-coupled receptors (GPCRs), which have 5 subtypes -D1-5. Fluorescence anisotropy (FA) assay has been used to study the ligand binding kinetics of many GPCRs.[ The model obtained by global analysis of kinetic data suggests that 8 ± 4% of CELT-419 is non-specifically Data from a single representative experiment performed in duplicate is shown. Data of a representative experiment from at least three independent experiments, performed in duplicates

  • 📰 GPCR Weekly News, May 8 to 14, 2023

    Hi GPCR lovers! Stay tuned for the latest buzz on GPCRs. GPCR Symposium on GPCR Activation and Signaling! Class B1 GPCRs. Therapeutics Sosei Heptares 2022 ESG report Exscientia Announces Sixth Molecule Created Through Generative AI Platform GPCR Ecosystem

  • 📰 GPCR Weekly News, August 28 to September 3, 2023

    Stay informed with our GPCR roundup. Mark your calendars for these important events: September 22: Save the date for the Dr. GPCR Symposium on 'GPCRs as Therapeutic Modalities' Showcase your project with a 1-minute abstract video Pharmaceuticals, As Independent Chairman Addex Adx71149 Phase 2 Epilepsy Study Expected To Readout Data GPCR Ecosystem

  • Hop in the Time Machine with GPCR: Unraveling the Future of Research! ⦿ Nov 24 - Dec 1, 2024

    Our Ecosystem provides an impressive array of platforms tailored for GPCR students and professionals GPCR University 🎥 Recorded GPCR Courses and Symposia / Summit 💲 Special Pricing on GPCR courses GPCR Events Mark your glittery calendar with dates in 2025 ! GPCR Jobs Seeking a job or the perfect employee? Book a date with our Chief Match Maker! GPCR community members Join the GPCR fan club and geek out with fellows! So much more to come!

  • PI(4,5)P 2-stimulated positive feedback drives the recruitment of Dishevelled to Frizzled in Wnt-β-c

    that the affinity of Fzd for Dvl was not affected by Wnt ligands, in contrast to other members of the GPCR Read more at the source #DrGPCR #GPCR #IndustryNews

  • 📰 GPCR Weekly News, May 22 to 28, 2023

    Hi GPCR lovers👋, Ready for exciting news in the GPCR world? Read them below! GPCR News, please subscribe to our monthly newsletter. Below is your Classified GPCR News at a glance for May 22 to 28, 2023. GPCR Activation and Signaling The adhesion GPCRs CELSR1-3 and LPHN3 engage G proteins via distinct activation GPCR Ecosystem

  • Extracellular signal-regulated kinases – a potential pathway for GPCR-targeted drug discovery

    Notably, G-protein-coupled receptors (GPCRs), representing the biggest drug target, have been revealed Historically, drug discovery efforts targeting GPCRs focused on G-protein-dependent signaling pathways In summary, targeting GPCR-activated ERK pathways represents a promising strategy for developing new By understanding the intricacies of GPCR signaling and utilising advanced assay technologies, researchers Minireview: targeting GPCR activated ERK pathways for drug discovery.

  • 📰 GPCR Weekly News, March 6 to 12, 2023

    GPCR Symposium event held on March 24th? GPCR Activation and Signaling Autoregulation of GPCR signalling through the third intracellular loop. John.B.Fenn Award Exscientia Announces Expansion of its Precision Oncology Pipeline Exscientia to Present Data Highlighting Pipeline and Precision Medicine Platform at AACR Fast Company has named Exscientia as one GPCR Ecosystem

  • 📰 GPCR Weekly News, May 15 to 21, 2023

    Hi GPCR buffs 👋! This week's GPCR papers feature a publication from Dr. Marta Filizola. GPCR Symposium on GPCR Activation and Signaling was a great success. GPCR News, please subscribe to your monthly newsletter. GPCR Activation and Signaling Monitoring the Reversibility of GPCR Signaling by Combining Photochromic GPCR Ecosystem

  • GPCR Weekly Whirlwind: Top Receptor Highlights from Sep 30 - Oct 6, 2024!

    Hey there, GPCR Enthusiasts! Are you geared up for your GPCR fix of the day? GPCR Event Spotlight 11th Adhesion GPCR Workshop    📍  Mexico City 📅 October 23 - 25, 2024 Hurry, there Classified GPCR News  Let’s dive into the   Classified GPCR News from September 30th to October 6th, Medical Officer and President of Nxera Pharma Japan Septerna files for IPO on strength of preclinical data Emerging Voices in GPCR Biology in Special Issue of Molecular Pharmacology GPCR Events, Meetings, and

  • Nanobodies as Probes and Modulators of Cardiovascular G Protein-Coupled Receptors

    October 2022 "Understanding the activation of G protein-coupled receptors (GPCRs) is of paramount importance Although many cardiovascular GPCRs have been extensively studied as model receptors for decades, new As a result, there is an ongoing need to develop novel approaches to monitor and to modulate GPCR activation nanobodies have been adopted to elucidate the structure, pharmacology, and signaling of cardiovascular GPCRs Read more at the source #DrGPCR #GPCR #IndustryNews

  • 📰 GPCR Weekly News, May 1 to 7, 2023

    Save the date and join us next week, May 19th, 2023 for the Dr. GPCR Symposium on GPCR Activation and Signaling. GPCRs in Neuroscience GPCR interactions involving metabotropic glutamate receptors and their relevance Methods & Updates in GPCR Research Multiplexed selectivity screening of anti-GPCR antibodies. GPCR Ecosystem

  • 📰 GPCR Weekly News, September 25 to October 1, 2023

    Hello GPCR enthusiasts! Join us for our weekly GPCR round-up. This week's highlights: Drs. Save the dates: November 2 - 4: We are excited to announce that we are sponsors of the GPCR Retreat and GPCR Symposia? GPCR Newsletter! GPCR Ecosystem

  • 📰 GPCR Buzz: August 5-11, 2024 | Top Highlights from DrGPCR University!

    Dear GPCR Enthusiasts! Get ready to save the dates! Dr. Kenakin and Hoare on '   Applying Pharmacology to Drug Discovery ' and ' Advanced Data Analysis for GPCR Discovering new ligands and unique GPCR behaviors for innovative drug profiles GPCR Event Highlight   11th Adhesion GPCR Workshop    Location : Mexico City Dates : October 23-25, 2024 Join us in the vibrant Joint Development of New Drugs Using Intralinks’ Virtual Data Room   GPCR Events, Meetings, and Webinars

  • 📰 GPCR Weekly News, April 24 to 30, 2023

    Greetings fellow GPCR enthusiasts! This week's GPCR papers feature publications from Drs. Thomas P. Check out some of the latest GPCR discoveries below! GPCR Symposium on GPCR Activation and Signaling on May 19th, 2023. GPCR News by subscribing to our monthly newsletter. GPCR Ecosystem

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