Search Results

Our results demonstrated that THC and CBD reduced cellular viability at concentrations above 30μM and

GPCR news content, make sure to subscribe to our monthly newsletter for Dr. GPCR News. If you'd like to suggest papers to include in our news, please email them to us at Hello@DrGPCR.com.

In a proof-of-principle study, we succeeded in showing that our CCR9-PROTAC is able to reduce CCR9 levels

Together, our data support that activation of cGAS/STING signaling mitigates organ fibrosis and suppresses

This conversation is part of a three episode series produced in collaboration with our partners at Celtarys

In this regard, luminescence-based biosensors have revolutionized our ability to monitor GPCR signaling

🚀✨ This Week’s Highlights: Congrats to: Ya-Tzu Li , our notable contributor, for her superb undergrad This transition will enable us to invest in higher-quality content and resources, ensuring our community

Our results provide additional evidence for the understanding of signaling pathways activated by GnIH

Our results suggest that strategies to selectively target OGR1 expression may represent a novel therapeutic

Our NMR analyses demonstrated that while the C tail-mediated interaction alone induces partial activation

Together, our findings reveal an important suppressive role of ADGRA1 in anxiety control and synaptic

Our PKC KO cell lines expand the repertoire of KO HEK293A cell lines available to research GPCR pharmacology

Our results suggest that GPR15/GPR15L have a pathogenic role in RA and their antagonizing could be a

Overall, our studies are expected to allocate new targets for cancer therapy.

Our previous work demonstrated that GPR3-mediated β-arrestin signaling modulates amyloid-β (Aβ) generation

Our earlier reports suggested that GPR3 enhances both neurite outgrowth and neuronal survival.

Overall, our work reveals insight into PI3Kγ regulation and identifies sites that may be exploited for

Surprisingly, our results also demonstrate that exposure to SFK inhibitors, including dasatinib or knockdown

Our site-directed mutagenesis results show that mutations of this interface impact the function of the

Enhancing our knowledge of these regulatory frameworks will provide critical insights into the contribution

flavonoids can target brain GPCRs and provide neuroprotection via inhibition of monoamine oxidases (hMAOs), our

This conversation is part of a three episode series produced in collaboration with our partners at Celtarys

Our results showed that the inhibition of cellular respiration hindered the internalization of F-Hst1

Overall, our data shows that, in TNBC, it is not universally true that kisspeptin/KISS1R stimulate migration

Taken together, our results indicate that the astrocytic Gi pathway plays an inhibitory role in neuroinflammation

Read the Premium edition here ➤ What our members say 🗣️ "Dr.

This is complimentary with other applications, and essential in our understanding of signaling pathways

Dear GPCR Enthusiasts , Get ready for an exciting learning experience with our newly updated Principles

Hello Readers👋, We're excited to share our weekly newsletter with you. Keep up-to-date with the latest research and advancements in the field with our convenient, weekly news

Our findings provide novel mechanistic insight into how GPR183 signaling in the spinal cord produces