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Results found for "pain research"

  • 📰 GPCR Weekly News, July 10 to 16, 2023

    Methods & Updates in GPCR Research Evaluation of Drug Responses to Human β2AR Using Native Mass Spectrometry Interactions of GPCRs, Ion Channels, and Transport Proteins (March 24 - 29, 2024) GPCR Jobs NEW Senior Research Technologies NEW Computational Protein Design (GPCR) Postdoctoral Fellow, Caron Lab Clinical Trial Associate Research

  • Verily links up with Sosei Heptares for GPCR drug discovery

    January 2022 "G-protein-coupled receptors’ star has been on the rise in biotech in recent years as researchers Among those hitching their wagons to that star are Verily and Sosei Heptares, which have struck a research

  • 📰 GPCR Weekly News, February 19 to 25, 2024

    migration of human T cells by directing GPCR and lipid second messenger signaling Methods & Updates in GPCR Research Congress of Basic and Clinical Pharmacology 2026 GPCR Jobs NEW Senior Scientist- Internal Medicine Research NEW Postdoctoral Scholar – Synaptic physiology, optical imaging, substance use disorder, pharmacology Research - Single-molecule Imaging Center Scientific Assistant Postdoctoral Fellowship- Mechanistic Biology Research

  • 📰 GPCR Weekly News, January 30 to February 5, 2023

    Keep up-to-date with the latest research and advancements in the field with our convenient, weekly news Methods & Updates in GPCR Research Deep-Learning-Enhanced Diffusion Imaging Assay for Resolving Local-Density Bioinformatics/Data Science at Department of Drug Design and Pharmacology Scientist/Senior Scientist (Research Biochemistry) Speculative Applications (Mass Spectrometry) Speculative Applications (Chemistry) Post-Doctoral Research Assistant Research Fellow - School of Physics and Astronomy Postdoctoral Research Associate (Fixed Term

  • 📰 GPCR Weekly News, January 29 to February 4, 2024

    immune responses and regulates GBP1 expression through GPCR receptor Mthl10 Methods & Updates in GPCR Research Basic and Clinical Pharmacology 2026 GPCR Jobs NEW Postdoctoral Fellowship- Mechanistic Biology NEW Research Scientist Post-Doc position Lead Researcher Senior Researcher in Structural Biology Post-Doctoral Fellow

  • Inverse Agonists, Lymphatic Fixes & β-arrestin Tricks

    Explore this week’s research, tools, and biotech insights in one place.

  • 📰 GPCR Weekly News, June 12 to 18, 2023

    Showcase your research by contacting us at Hello@DrGPCR.com Stay informed with Dr. Methods & Updates in GPCR Research Spatiotemporal GPCR signaling illuminated by genetically encoded fluorescent on Gliovascular Unit of Glioblastoma Associate Director / Director, Clinical Operations Postdoctoral Research

  • 📰 GPCR Weekly News, May 8 to 14, 2023

    Conference Simon Bekker-Jensen and Mette M Rosenkilde received two proof of concept grants from European Research October 25 - 27, 2023) GPCR Jobs Vice President, Medical Affairs Associate Scientist - Technology Senior Research Scientist/Principal Scientist- Technology Tissue Culture Scientist/Tissue Culture Manager Postdoctoral Researcher Director - Targeted Oncology Senior Scientist - Antibody Engineering Scientist—Immuno-Oncology Convergent Research

  • Innovative Data-Driven Solutions: The pHSense Revolution

    From Bench to Breakthrough: Why pHSense Matters Decades of GPCR research have relied heavily on engineered The biological validation came from Jean-Philippe Pin’s group at the Genomic Functional Institute in behind-the-scenes access to GPCR innovators, exclusive deep-dives, and practical tools to accelerate your research

  • How Breakthroughs Happen: Eric Trinquet on Innovation, Serendipity & GPCRs

    Changed After This Data: Trinquet pushed pHSense toward rapid commercialization—pivoting it from a research collaborations—with Durham University chemist David Parker on the probe chemistry, and with Jean-Philippe Pin behind-the-scenes access to GPCR innovators, exclusive deep-dives, and practical tools to accelerate your research

  • Overview of adhesion GPCRs self-activation

    modulate protein-protein interactions; and also by the presence of the GPCR-Autoproteolysis INducing (GAIN endoplasmic reticulum, many of these receptors are cleaved at the GPCR Proteolysis Site motif of the GAIN These crystal structures showed how the Stalk region, which is a short peptide released from the GAIN during auto-proteolysis, has a β-lamin conformation and is held within the GAIN surrounded by numerous knowing the factors that determine the selectivity of coupling represents a very interesting area of research

  • Harnessing Deep Mutational Scanning for Enhanced Drug Discovery

    By systematically mutating every amino acid in the protein and assessing the resulting phenotype, researchers By examining how mutations in the target protein affect its interaction with the drug, researchers can resources, including time, financial investment, and specialised expertise, limiting accessibility for some research

  • GPCR Drug Discovery at Discovery on Target: Why This Track Is About More Than Receptors

    Over the years, we’ve built a global network of researchers, biotech leaders, and pharma innovators who Scientist GPCR pathways intersect with oncology, CNS, metabolic, cardiovascular, immunology, and fibrosis research

  • Decoding Schild Analysis: The Pharmacologist’s Lens on Competitive Antagonism

    In this session, you’ll gain: A clear conceptual map of Schild analysis and its origins. It encourages skepticism—forcing researchers to prove competition before quantifying it.

  • 📰 GPCR Weekly News, April 24 to 30, 2023

    Methods & Updates in GPCR Research NanoBiT- and NanoBiT/BRET-based assays allow the analysis of binding Meeting IRN I-GPCRNet (October 25 - 27, 2023) GPCR Jobs NEW Associate Scientist - Technology NEW Senior Research Scientist/Principal Scientist- Technology NEW Tissue Culture Scientist/Tissue Culture Manager Postdoctoral Researcher Director - Targeted Oncology Senior Scientist - Antibody Engineering Scientist—Immuno-Oncology Convergent Research

  • Predicting GPCR Function: Inside the Carlsson Lab’s Modeling Toolbox

    chemistry, and drug discovery —rethinking how simulations, docking, and machine learning can transform GPCR research But success depends on researchers who can manage expectations, build trust, and integrate across disciplines

  • 📰 GPCR Weekly News, November 6 to November 12, 2023

    migration of human T cells by directing GPCR and lipid second messenger signaling Methods & Updates in GPCR Research 12 - 17, 2026 | 20th World Congress of Basic and Clinical Pharmacology 2026 GPCR Jobs NEW Post-Doc Research Associate NEW Postdoctoral Fellow Research Scientist/Postdoctoral Associate in Computational Chemistry

  • Professor Charlotte Deane Joins Exscientia as Chief Scientist of Biologics AI

    Prior to this, Professor Deane was Deputy Executive Chair of the Engineering and Physical Sciences Research Council at UK Research and Innovation (UKRI).

  • 📰 GPCR Weekly News - January 2 to 8, 2023

    Keep up-to-date with the latest research and advancements in the field with our convenient, weekly news Methods & Updates in GPCR Research Small Molecule Tools to Study Cellular Target Engagement for the Intracellular Twist Bioscience and Astellas Enter into Multitarget Antibody Discovery Research Collaboration Neurocrine

  • Specific Functions of Melanocortin 3 Receptor (MC3R)

    In addition to its function about weight gain and appetite control mechanisms of MC3R, recent studies In this review paper, we aimed to point out the importance of the MC3R regulations in three main concepts

  • A robust and Efficient FRET-Based Assay for Cannabinoid Receptor Ligands Discovery.

    Cannabinoids as Anticancer Drugs: Current Status of Preclinical Research. First Synthetic Allosteric Modulator of the CB2 Receptors and Evidence of Its Efficacy for Neuropathic Pain Nucleic Acids Research   2021 , 49 (12), e72–e72. https://doi.org/10.1093/nar/gkab237 . (20)      Degorce A.; Bazin, H.; Tinel, N.; Durroux, T.; Prézeau, L.; Trinquet, E.; Pin, J.-P.

  • The Impact of CB1 Receptor on Nuclear Receptors in Skeletal Muscle Cells

    Thus, the aim of the current research was to explore the influence of CB1 receptor stimulation and inhibition The present research demonstrated that 10 nM of ACEA notably amplified mRNA gene expression of NR4A1 Further research is required to fully delineate their role(s)."

  • 📰 GPCR Weekly News, July 24 to July 30, 2023

    Lukas Grätz, David Gloriam, and Gunnar Schulte’s research on Unveiling pathway selectivity in Frizzleds Methods & Updates in GPCR Research Strategies for acquisition of resonance assignment spectra of highly Robert Lefkowitz Lab Senior Research Specialist - Natural Sciences - Surgery Senior Scientist- Membrane

  • 📰 GPCR Weekly News, June 5 to 11, 2023

    Methods & Updates in GPCR Research A Peptidisc-based Survey of the Plasma Membrane Proteome of a Mammalian Confo Therapeutics Enters Into Research Collaboration For GPCR-Targeting Antibody Discovery With AbCellera on Gliovascular Unit of Glioblastoma Associate Director / Director, Clinical Operations Postdoctoral Research

  • 📰 GPCR Weekly News, February 12 to 18, 2024

    and Signaling Fine-tuning activation specificity of G-protein-coupled receptors via automated path searching Heptares Operational Highlights and Consolidated Results for 12 Months ended 31 December 2023 Pioneering Research Workshop July 12 - 17, 2026 | 20th World Congress of Basic and Clinical Pharmacology 2026 GPCR Jobs NEW Research - Single-molecule Imaging Center Scientific Assistant Postdoctoral Fellowship- Mechanistic Biology Research

  • Join Dr. GPCR Summit 2022 in 3 simple steps!

    Come join us from October 10 to 16 to hear about exciting #GPCR research from amazing speakers.

  • Dr. GPCR Virtual Cafe with Matthew Eddy - New date!

    Don't miss the chance to listen to his latest research on the field.

  • 📰 GPCR Weekly News, December 18 to 31, 2023

    mediated neuroprotective mechanism through autophagy-mediated NLRP3 degradation Methods & Updates in GPCR Research Principal Investigator, In Vitro Biology NEW Associate Scientist Postdoctoral Scholar - O’Neill Lab Junior Research Scientist Postdoctoral Fellow Post-Doc Research Associate Assistant/Associate Professor Explore Dr.

  • Therapeutic validation of an orphan G protein‐coupled receptor

    Some studies have also reported GPR84 involvement in pain, atherosclerosis, and even metabolic disorders

  • Use of CRISPR/Cas9-edited HEK293 cells reveals that both conventional and novel protein kinase C...

    Our PKC KO cell lines expand the repertoire of KO HEK293A cell lines available to research GPCR pharmacology isozymes generally lack specificity and/or potency, we present the PKC KO cell lines as more specific research

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