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Results found for "Brigitte Kieffer"
Posts (180)
- Structures of β 1-adrenergic receptor in complex with Gs and ligands of different efficacies
August 2022 "G-protein-coupled receptors (GPCRs) receive signals from ligands with different efficacies , and transduce to heterotrimeric G-proteins to generate different degrees of physiological responses Previous studies revealed how ligands with different efficacies activate GPCRs. Analyses reveal similar overall complex architecture, with local conformational differences. ligands, with residue-specific functional differences.
- Characterization of a new WHIM syndrome mutant reveals mechanistic differences in regulation of ...
Characterization of a new WHIM syndrome mutant reveals mechanistic differences in regulation of the chemokine Interestingly, there were also significant differences in receptor degradation, with S339fs5 having a
- Differences across sexes on head-twitch behavior and 5-HT2A receptor signaling in C57BL/6J mice
However, the pharmacokinetic properties of DOI differed among sexes - brain and plasma concentrations Together, these results suggest strain-dependent and sex-related differences in the behavioral and pharmacokinetic
Other Pages (12)
- Dr. Amynah Pradhan | Dr. GPCR Ecosystem
Brigitte Kieffer , where she studied ligand-directed signaling at the delta-opioid receptor. It takes <60 seconds and makes a big difference. ★ Review on Apple Podcasts ★ Rate on Spotify ✉️ Send
- Adenosine A3 receptor has been proposed to have significant roles in metabolism and immune responses. Check out this study to understand how it affects metabolic dysfunction-associated steatotic liver progression. Subscribe to the Dr. GPCR Newsletter 📰 and get the latest GPCR News delivered to your inbox ➡️https://buff.ly/42b6ra3 #gpcr #drgpcr | Dr. GPCR Ecosystem
a3ar-antagonism-mitigates-metabolic-dysfunction-associated-steatotic-liver-disease-by-exploiting-monocyte-derived-kupffer-cell-necroptosis-and-inflammation-resolution
- From Rare Earth Probes to Internalization Assays: The pHSense Story with Dr. Eric Trinquet | Dr. GPCR Ecosystem
Episode How Eric and his team reimagined rare earth complexes to develop pH-sensitive probes with tunable brightness It takes <60 seconds and makes a big difference. ★ Review on Apple Podcasts ★ Rate on Spotify ✉️ Send
