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Home → Flash News → How sensitive can a GPCR really be How sensitive can a GPCR really be? How disease can hijack signaling organization — and what that means for drug discovery.

A breakthrough in GPCR imaging reveals a full native pancreatic islet and advances how GLP-1R can be Lighting up a native pancreatic islet isn’t just a technical win it’s a shift in what GPCR imaging can Lighting up a native pancreatic islet isn’t just a technical win — it’s a shift in what GPCR imaging can

Home → Flash News → What can an updated profile do for you? GPCR Profiles What can an updated profile do for you?

Take advantage of a platform where you can network within your field! Take advantage of a platform where you can network within your field!

Home → Flash News → Did you know allosteric modulators can change the GPCR G protein subtype selectivity Published on December 12, 2024 Category GPCR Weekly News Did you know allosteric modulators can change

If you’re an Ecosystem Member, you can learn something new every day! If you’re an Ecosystem Member, you can learn something new every day!

Can you guess what’s his favorite GPCR? ✅ Hear his response: Ep 164 with Dr. Can you guess what’s his favorite GPCR? ✅ Hear his response: Ep 164 with Dr.

Home → Flash News → Do you know we can discover allosteric modulators that bind to the intracellular Published on October 29, 2024 Category GPCR Weekly News Do you know we can discover allosteric modulators

Check out what you can learn this year from the master, Dr. Check out what you can learn this year from the master, Dr.

Home → Flash News → Can we preserve opioid pain relief without the side effects? GPCR Podcast Can we preserve opioid pain relief without the side effects?

Check out this paper to see how molecular dynamics simulation can be used to explore its constitutive Check out this paper to see how molecular dynamics simulation can be used to explore its constitutive

This new review explores how tweaking peptide drugs can boost efficacy, reduce side effects, and unlock This new review explores how tweaking peptide drugs can boost efficacy, reduce side effects, and unlock

GPCR location within the cell can change everything: function, pharmacology, and even drug response. GPCR location within the cell can change everything: function, pharmacology, and even drug response.

Home → Flash News → Did you know that cell types can affect the GPCR-mediated signalling cascade? #gpcr #drgpcr Published on January 14, 2025 Category GPCR Weekly News Did you know that cell types can

Home → Flash News → Did you know that certain ergot derivatives can produce wash-resistant signalling drgpcr Published on May 19, 2025 Category GPCR Weekly News Did you know that certain ergot derivatives can

Here, you can make changes to your content, add new fields, create dynamic pages and more. You can create as many collections as you need. You can also collect and store information from your site visitors using input elements like custom forms Be sure to click Sync after making changes in a collection, so visitors can see your newest content on

Here, you can make changes to your content, add new fields, create dynamic pages and more. You can create as many collections as you need. You can also collect and store information from your site visitors using input elements like custom forms Be sure to click Sync after making changes in a collection, so visitors can see your newest content on

Here, you can make changes to your content, add new fields, create dynamic pages and more. You can create as many collections as you need. You can also collect and store information from your site visitors using input elements like custom forms Be sure to click Sync after making changes in a collection, so visitors can see your newest content on

That’s why a compound like phenoxybenzamine can knock down receptor populations after just a brief exposure And why slow-dissociating allosteric inhibitors can reshape signaling curves for hours — or even days When persistent binding meets structured tissues, this effect can amplify or collapse. High-affinity molecules can get trapped at the periphery of a tumor, never reaching the core.

How can I sponsor the 2021 Summit? You can pre-record your talk. We recommend submitting pre-recorded talks. What does this mean? Pros: You can polish your recording to your satisfaction. Anyone can watch it from anywhere, even multiple times. Can I present a live talk or event? How?

Can I reschedule or cancel our meeting? Yes, you can reschedule or cancel our meeting through Calendly. Can I promote my work or projects during the podcast? Absolutely! Can I listen to the episode after it’s been recorded? Can I watch the video podcast after it’s been published?

GPCR brand ambassador affiliate program Who can be a Dr. GPCR ambassador? Can I invite someone to participate? Yes! You can invite anyone to participate, and we welcome anyone if they are qualified. You can leave the program at any time by contacting us. Dr. You can take part in other affiliate programs as well as be part of ours.

Unlike reversible ligands, their impact can persist long after the compound is gone — creating durable In this week’s lesson, you’ll unpack: Why low offset rates can mimic covalent effects without forming Understanding irreversible interactions can mean the difference between a stalled program and a strategic

The explosion of biomedical data such as in genomics, structural biology, and pharmacology can provide ML/AI can be powerful for identifying abstract patterns within large data where traditional methods would This comes without the need for manual feature engineering as systems can learn through implicit rules How can we best leverage these exciting new techniques in areas such as protein structure prediction,

pharmacologists navigating a fast-changing field: “Try to keep a finger on the pulse of as much as you can New ideas come up, and if we can encapsulate them and expose them, you can just hit a button, hear about

about structure, function, and discovery — but Jens Carlsson reminds us: the real test isn’t whether we can explain today’s data, it’s whether we can predict tomorrow’s results . With tools like AlphaFold , his lab can now model receptor–peptide complexes in seconds — an achievement

Can I make a donation on behalf of a company? Can I become a monthly supporter? Absolutely. Monthly donations sustain long-term programs and can be changed at any time. Can I be recognized publicly? Together, we can accelerate GPCR discoveries and develop more effective drugs for everyone. 👉 Donate

You can join us for free when you become a Dr. GPCR Ecosystem site member, which is also free! You can participate: As an attendee by becoming a site member. You can verify it too by checking out the schedule on our website. before September 30th, 2022 You'll need a 1-minute video abstract in addition to the written version You can

Discover how enzyme inhibition can enhance drug discovery strategies. noncompetitive, mixed, uncompetitive), the messy truth of CYP450 allostery and DDIs, and why allosteric control can

Discover how organizations in the GPCR field can leverage the Dr. GPCR Strategic Partner Request Your Quote How Organizations can benefit from Dr. GPCR Ecosystem? Post you job description and since this is a closed Ecosystem, you can (if you'd like) share the contact