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for their study on Constitutive internalisation of EP2 differentially regulates G protein signalling Ethan Dintzner, Demet Araç, et al. for their work on The far extracellular CUB domain of the adhesion GPCR

Terry’s Corner: Why Binding Kinetics Matter More Than Affinity In drug discovery today, time wasted is interpret kinetic binding experiments and recognize when a drug’s rate of onset and offset matter more than

When complexity grows faster than strategy, biotech companies begin to fall apart quietly. 👉 This article When complexity grows faster than clarity 👉 Early-stage biotech is complex by default. The problem begins when they expand faster than the company’s ability to make clear decisions. More experiments feel safer than fewer deliberate ones.   Scientists trust leadership because decisions are grounded in logic rather than mood.

cellular environments Biased signaling in practice — Why the promise of biased agonism is more complicated than Biased signaling is real but harder to exploit than expected GPR68 couples to both Gq and Gs, and the A career redirected by a dinner and an empty schedule In 1975, Dr. Insel was the only unmarried scientist at a dinner with Al Gilman. During dinner with colleagues and Alfred Gillman , co-recipient of the 1994 Nobel Prize in Physiology

At the height of curiosity, a seemingly naïve idea at the dinner table led to a side project by which