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Deficiency of β-arrestin2 alleviates apoptosis through GRP78-ATF6-CHOP signaling pathway in primary Sjögren's In vivo, we found that inhibition of GRP78-ATF6-CHOP apoptosis signaling improved ESS symptoms, and the salivary gland indices, and improved tissue integrity in the ESS model by downregulating GRP78-ATF6-CHOP In addition, β-arrestin2 depletion downregulated GRP78-ATF6-CHOP apoptosis signaling to alleviate cell of pSS and that β-arrestin2 encourages inflammation-induced epithelial apoptosis through GRP78-ATF6-CHOP

References: Jin, B. K., Odongo, S., Radwanska, M., & Magez, S. (2023). G., Choi, H. J., Fung, J. J., Pardon, E., Casarosa, P., Chae, P. S., Devree, B. T., Rosenbaum, D.

Structure-guided design of a peripherally restricted chemogenetic system Hye Jin Kang , Brian E Krumm

<< Back to podcast list Strategic Partner(s) Jacob Lee & Jin Choe About this episode In this special Jacob Lee and Jin Choe met in ninth grade in English class and have been friends since. Although both went to the same college, Jacob and Jin choose different career paths. shared his struggles of managing samples and an incredible amount of data and projects in the lab with Jin GPCR Ecosystem Jin Choe on LinkedIn Jin Choe on Dr. GPCR Ecosystem Enjoying the Dr. GPCR Podcast?

Hormone Receptors and Hearing and Balance Receptors Abstract Only Available for AGPCR24 Attendees About Jin-Peng Jin-Peng Sun on the web Google Scholar LinkedIn < Previous Session Next Session >

<< Back to podcast list Strategic Partner(s) Chloe Hicks About Chloe Hicks Chloe Hicks will graduate Chloe Hicks on the web ORCID LinkedIn Dr. GPCR Enjoying the Dr. GPCR Podcast? Leave a Review.