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GPCR Summit 2022 is less than a month away!

February 2022 "Switzerland Today, InterAx Biotech is pleased to announce that Carola Weiss has joined Carola Weiss is a Senior Executive with more than 20 years of international experience in the biopharmaceutical Carola Weiss’ professional career brings deep expertise in business development, marketing & sales, licensing

Jürgen Wess and Liu Liu for their study on A novel function of the M2 muscarinic receptor Drs.

Now, there’s less competition and more opportunity.”

In fact, it all began with a phone call (from Bruce Merrifield, no less) encouraging Sakmar to work on

C., Wess, J., & Kobilka, B. K. (2013).

Yet, far less time is spent scrutinizing the structural logic and origin  of the molecules we screen Less than ~15% of higher plant species, <5% of bacterial and fungal species, and only a fraction of marine

The move comes less than three weeks after X4 pulled together a $55 million PIPE and amended a loan facility

We will first summarize their prominent roles in GPCR pharmacology before transitioning into less well-explored

In a constant effort to develop drugs with less side effects, and tools to explore the ORs nature and

through the mu-opioid receptor, blunts the brainstem’s inspiratory drive so that each breath draws in less two drugs, there was a potentiation of fentanyl’s effect on tidal volume—mice were bringing in even less

Serafini’s work on RGS proteins suggests a quieter, but no less powerful, frontier in the fight against

Here, we will focus on the relatively less well-studied effects of GPCRs in cardiac fibroblasts, focusing

In less than a decade, nanobodies, or recombinant single-domain antibody fragments from camelids, have

November 2021 "Target class-specific libraries mean you need to screen less to identify high-quality

In contrast, less is known about the expression and function of the GLP-1R in human T cells.

They stall because the data becomes a mess.

For proteins with low sequence similarity to available templates, homology models tend to be less accurate

ensures that you remain on top of your findings but also makes the thesis-writing process significantly less

Although less characterized, canonical CKRs have also been shown to not only directly regulate migration

Today, success depends less on manual precision and more on experimental design, data interpretation,

dynamics of GPCR activation has always been a challenge because G protein activation in cells occurs in less

It began with an unmet need: how to track Gq-coupled GPCR activity without the mess of calcium flux or

Academic success is less about prestige than about impact.

Understanding the evolutionary conservation of these residues can lead to the development of drugs that are less

Extending Schild to Partial Agonists Partial agonists complicate things—they activate receptors but less

It’s less bureaucratic than most outsiders think.

It’s built for the GPCR community—by people who live the science—so you spend less time sifting and more

Reviews, GPCRs, and more Diversification processes of teleost intron-less opsin genes.

These agonists exhibit less interaction with ECL3, resulting in an open conformation of the TM6-ECL3-