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Sara Marsango and Graeme Milligan for their research on the Regulation of the pro-inflammatory G protein-coupled

In a recent collaborative study, 16 synthetic cannabinoid receptor agonists (SCRAs) were evaluated using SCRAs—although often known for their undesired toxicological profile—offer a chemically diverse set of physiologically relevant affinity measurements for CB2 ligands  What the screening results reveal about 16 SCRAs CB2 Competitors The study began with a one-point displacement screen, assessing how each of the 16 SCRAs Among 16 SCRAs evaluated, three compounds—AAN396, AAN397, and AAN405—emerged as nanomolar binders with

Sara, T.C. Südhof, and ¨ E.T. Kavalali. 2001.

In this study Marsango et al. address two key questions in GPR84 biology and pharmacology: 1. how GPR84

family mediates βarrestin-independent GPCR endocytosis Valeria Robleto , Ya Zhuo , Joseph Crecelius , Sara

This can be appreciated when talking about SCRAs (Synthetic Cannabinoid Agonists), as one of the series It highlights the difference in affinity of compounds such as SCRAs and other synthetic cannabinoids. https://doi.org/10.1056/NEJMoa1610300 . (10)      Rosado, T.; Gonçalves ,Joana; Luís ,Ângelo; Malaca ,Sara

Prézeau, for their research on Heterodimers revolutionize the field of metabotropic glutamate receptors Kara

fantastic work on Germline mutations in a G protein identify signaling cross-talk in T cells Victoria Saca