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development of biased ligands, which promote the engagement of the receptor with a certain effector, thus therapeutic applications are situated in the area of chronic inflammatory disease (Proudfoot, Power, and Schwarz

higher potency in the CB1R. [9,10] 1.2 Novel fluorescent strategies for CBR binding affinity assays Thus narrow bands and high stokes shift, which prevent cross-excitation and cross-emission phenomena.[18] Thus GPCRs are not suitable for antibody use due to steric hindrance and reverse binding, thus, other strategies Thus, the same set of compounds used for CB1R competition assays was used in CB2R. Table 3. D.; Irizarry, L.; Trecki, J.; Schwartz, M.; Gerona, R.

fascinated by G protein-coupled receptors (GPCRs) due to a stay as a scholarship student in the lab of Thue Schwartz (Copenhagen, Denmark).

GPCRs led Maria to Thue W. Schwartz’s lab in Copenhagen where she completed her postdoctoral training.

then moved to Denmark, where he trained at the University of Copenhagen under supervision of Professor Thue Schwartz, and worked closely with Dr Birgitte Holst studying structural and mechanistic properties of also shared their appreciation for documentaries showcasing manufacturing processes and the value of true