Search Results

GPCR-BSD: a database of binding sites of human G-protein coupled receptors under diverse states Fan Liu , Han Zhou , Xiaonong Li , Liangliang Zhou , Chungong Yu , Haicang Zhang , Dongbo Bu 🤩 Seriously, why GPCR Events to keep you informed and engaged GPCR Jobs connecting candidates with positions Direct line This strategic decision to limit free content is essential as we need to increase revenue to support

assay and Kd= 42nM in Tag-lite®). Competition experiments of binding of fluorescent ligand CELT-335 to living HEK-293 T cells expressing W.; Wu, Y.; Zhao, S.; Shui, W.; Li, S.; Korde, A.; Laprairie, R. B.; Stahl, E. L.; Ho, J. Cell   2016 , 167  (3), 750-762.e14. https://doi.org/10.1016/j.cell.2016.10.004 . (5)         Li, X.; A Fluorescent Ligand-Binding Alternative Using Tag-Lite® Technology.

GPCR-focused programs, the ability to visualize receptor localization, internalization kinetics, and ligand Yet, despite remarkable progress, HCS workflows remain vulnerable to several performance-limiting factors How Fluorescent Ligands Strengthen HCS Assays: The Case of CELT-331 Fluorescent ligands are now considered Their ability to visualize ligand–receptor interactions directly in living cells produces data that are information that clarifies receptor behavior under different ligand conditions.

<< Back to podcast list Dr. GPCR Podcast Strategic Partners Dr. Nicolas Gilles About Dr. His strongest expertise lies in therapeutic target identification and all the steps from venom manipulations When the pharmacological properties of these new ligands are deemed exceptional, a lead optimization Nicolas Gilles on the web Google Scholar LinkedIn Dr. GPCR Enjoying the Dr. GPCR Podcast? : The Evolution of GPCR Research How GPCR Spatial Signaling Sparked a Scientific Journey Thanks for listening

Home → Flash News → Terry's Corner is Officially LIVE! TerrysCorner #DrugDiscovery Published on July 2, 2025 Category Terry's Corner Terry's Corner is Officially LIVE But what if the real opportunity lies in the chemical matter we throw at them?

For decades, molecular modeling focused on explaining — rationalizing why a ligand binds, why a mutation With tools like AlphaFold , his lab can now model receptor–peptide complexes in seconds — an achievement A good model doesn’t just match published structures; it forecasts new biology, new ligands, and new That’s where the future of GPCR research lies — not in describing the past, but in anticipating it.