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Monserrat Avila Zozaya on the web LinkedIn Antony Boucard Lab Dr. John Azietaku on the web LinkedIn Dr. GPCR About Ya-Tzu Li Ya-Tzu is a Master's student at the University of South Florida, utilizing large-scale Ya-Tzu Li on the web LinkedIn Dr. Cam Sinh Lu on the web LinkedIn Dr. GPCR Unlock the Full Dr.

<< Back to podcast list Strategic Partner(s) Dr. Nicolas Gilles About Dr. Nicolas Gilles "Dr. His strongest expertise lies in therapeutic target identification and all the steps from venom manipulations When the pharmacological properties of these new ligands are deemed exceptional, a lead optimization Nicolas Gilles on the web Google Scholar LinkedIn Dr. GPCR Unlock the Full Dr. GPCR Learning Ecosystem ✔ Full Masterclass library ✔ Terry's Pharmacology Corner ✔ Advanced GPCR courses

. << Back to podcast list Strategic Partner(s) From Curiosity to Breakthrough: Ajay Yekkirala on GPCR Innovation What if the key to safer, more effective drugs lies in asking the right questions — and daring is the heart of scientific innovation Who Should Listen PhD students and postdocs exploring biotech careers Seeing the limits of traditional drug discovery, he later co-founded Superluminal Medicines, a company Ajay Yekkirala on the web Superluminal Medicines LinkedIn Tune in now to hear how asking “what if?”

. << Back to podcast list Strategic Partner(s) From Rare Earth Probes to Internalization Assays: The the IP-One kit, Tag-lite, and now, pH Sense. HTRF, the IP-One kit, and the Tag-lite platform into widespread use. His passion lies in turning cutting-edge probe chemistry into robust, scalable tools for drug discovery GPCR X Revvity Collaboration Want more like this? Join the Dr.

. << Back to podcast list Strategic Partner(s) Arun Shukla: How Two Arrestins Regulate 800 GPCRs The The answer lies somewhere in the diversity of receptor architectures — long C-termini versus long ICL3s What a one-line email to Bob Lefkowitz can do Toward the end of his PhD in Frankfurt, Dr. That is where I realized research is what I want to do for the rest of my life." Arun Shukla Lab Google Scholar PubMed Wikipedia LinkedIn Twitter Dr.

. << Back to podcast list Strategic Partner(s) Robert J. Lefkowitz's lab was getting nowhere screening plasmid libraries. This is why scientific lineages exist. It was that serendipitous event that basically changed the entire course of my life and career." His legacy lies in the numerous discoveries he and his team made in the GPCR field and in all those who

Email us if you'd like to teach or if you'd like to learn more about any particular topic. 🗓️ Upcoming 4-Week Course: Development of GPCR Ligands as Therapeutic Drugs starting March 20 – April 10, 2025 ( Highlights of the Week How Ligands Achieve Biased Signaling toward Arrestins Stéphanie Gaillard , Neha A combined in silico approach to design peptide ligands with increased receptor-subtype selectivity Adam type-dependent involvement of Gi, Gq, Gs proteins and protein kinase C Qin Wang , Wenwen Hao , Jing Li

Live scientific exchanges with leading GPCR experts. GPCR University Try it for 14 days Upcoming live sessions Your next Live Masterclass Session is waiting Every session recorded Can't make it live? Are the sessions live or recorded? Masterclass sessions are conducted live with an invited expert. See what it feels like for 14 days.

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Graciela Piñeyro on what happened when her lab tested biased agonism at the μ-opioid receptor across 25 ligands Strategic Partner(s) Graciela Piñeyro: Partial Agonism, Receptor Recycling, and the Limits of Bias For Across 25 ligands profiled at the μ-opioid receptor, the team found no bias, only partial agonism. from Pfizer — they could not identify a ligand-bias signature. Graciela Pineyro on LinkedIn Dr. Graciela Pineyro - University of Montreal Dr.

. << Back to podcast list Strategic Partner(s) Anita Nivedha: Computational Dynamics of Ligand Bias in Understanding how ligand binding leads to specific signaling outcomes—particularly ligand bias toward can reproduce experimentally measured ligand bias. Episode Timeline 00:00 — Introduction: From ligand binding to receptor signaling Overview of ligand bias It combined both things I liked.

. << Back to podcast list Strategic Partner(s) Smells Like GPCR Spirit: Cracking Olfactory Codes with Like many, his path to GPCR research wasn’t linear—it evolved through academic exploration and mentorship Build predictive models to discover new ligands . Explore online resources like “Talktorials.” Despite their relevance, they remain understudied due to the limited knowledge of their ligands and the

<< Back to podcast list Strategic Partner(s) Dr. Simone Prömel & Dr. Ines Liebscher About Dr. Together with Ines Liebscher, Simone is leading an EU-funded COST Network on Adhesion GPCRs: CA18240 Ines Liebscher Dr. With the little knowledge on these receptors available, there were multiple questions to tackle. Ines Liebscher on the web Website LinkedIn Researchgate Dr. GPCR Ecosystem Unlock the Full Dr.

Livingston on allosteric opioid modulators, receptor internalization, and navigating the transition from academic GPCR research to biotech. << Back to podcast list Strategic Partner(s) Kathryn Livingston: states, live-cell microscopy reveals what happens between them. Kathryn E Livingston Dr. Kathryn E Livingston on the web LinkedIn ResearchGate Pubmed Google Scholar Dr.

Discover how Celtarys Research is transforming GPCR assay development with fluorescent ligands in this GPCR means for the global research community. << Back to podcast list Strategic Partner(s) Custom Molecules , Fluorescent Probes: When Chemists Think Like Biologists with Dr. Their approach is highly consultative—they don’t just sell ligands, they co-develop solutions. Maria Majellaro on the web LinkedIn ResearchGate Unlock the Full Dr.

. << Back to podcast list Strategic Partner(s) Graciela Pineyro: Resilience, Lab Life, and the Zoom Effect GPCR Podcast series capturing the realities of scientific life, returns to Dr. She does not separate this from the scientific conversation — and the listener shouldn't either. People that usually do not speak so much in the lab meetings were speaking a little bit more through Graciela Pineyro on LinkedIn Dr. Graciela Pineyro - University of Montreal Dr.

The discussion covers why degenerate oligos had been the bottleneck for library quality, how a "library of libraries" strategy sidesteps the ten-billion-variant ceiling that caps any single phage library, library of libraries as an answer to the diversity ceiling of single phage libraries Greenfield target his library of libraries. One way around that limited diversity is to actually have multiple libraries."

Eleonora Comeo synthesizes fluorescent ligands to watch adenosine receptor pharmacology happen in living cells - and explains why targeting these receptors keeps failing. << Back to podcast list Strategic Partner(s) Eleonora Comeo: Fluorescent Ligands and the Pharmacology of Adenosine Receptors Adenosine You would just like to run around screaming." Eleonora Comeo on the web LinkedIn ResearchGate Pubmed Google Scholar Dr.

Explore GPCR lipid rafts, bitter taste receptor pharmacology, and data integration in this expert interview Keyvan Sedaghat. << Back to podcast list Strategic Partner(s) How Lipid Rafts Organize GPCR Signaling Keyvan Sedaghat discussing how GPCR function is shaped by lipid raft compartmentalization, the expanding Sedaghat details the construction of an open-access GPCR-lipid raft database and reviews key findings Guest on the Web LinkedIn 7TMR-RAFT database Unlock the Full Dr.

Lin and Ball of GeneTex on GPCR antibody characterization, recombinant monoclonals, five-pillar validation , and the LGR5 challenge. << Back to podcast list Strategic Partner(s) Lin and Ball: GPCR Antibody Characterization Yet the GPCR field has lived with a quiet, persistent problem: antibodies that pass catalog-level QC, Chia-Yi Lin and Alexander Ball, both scientists-turned-industry professionals at GeneTex, trace how the Chia-Yi Lin "If you don't choose the immunogen properly, you're already messed up.

. << Back to podcast list Strategic Partner(s) Finance is Science too: How Numbers Keep the Lights On Both Chuck and Joe agree: accounting is like solving puzzles. It's about structure, order, and breakthrough moments , not unlike the life of a researcher. They avoid companies that don’t align with their values, like the vaping industry. GPCR Learning Ecosystem ✔ Full Masterclass library ✔ Terry's Pharmacology Corner ✔ Advanced GPCR courses

Maria Waldhoer on why endpoint GPCR assays miss most of what ligands do — and what kinetic pharmacological fingerprints reveal instead. << Back to podcast list Strategic Partner(s) Maria Waldhoer: Pharmacological Fingerprints and the Limits of Bias Dr. of InterAx Biotech AG, argues that endpoint assays — the field's default way of characterizing GPCR ligands "What endogenous level would you like me to mimic?"

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are saying about this podcast "You made it a very comfortable and engaging experience, and it felt like I've listened to the episodes multiple times and it's just like being at a conference getting new ideas Am very grateful for Dr GPCR livening up the week in these difficult times! Sam @Pharmamechanic Listen and subscribe where you get your podcasts

We have a catalogue of over 30 fluorescent ligands for different families of GPCRs, including adenosine interactions in living cells. High Content Screening Service Live‑cell HCS imaging in HEK‑293T–hCB2R with fluorescent ligand CELT-331 Product Catalog GPCR Ligands Our GPCR fluorescent ligands are the ideal solution for your High Throughput Mestre Mateo 2, Santiago de Compostela, 15706, Spain Email Website LinkedIn

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Free live webinar, June 25. < Back to Webinars 📅 Thursday, June 25, 2026 at 3:00:00 PM UTC 🤝 Webinar Expression levels in common cell lines are often low. The literature often disagrees on which antibodies actually work. Previous Webinar Next Webinar Don’t Miss the Next Live Session Dr. GPCR membership gives you access to all upcoming live, interactive webinars. Free.

unknown adhesion GPCRs in Drosophila - receptor discovery, nocifensive behavior, and human disease links . << Back to podcast list Strategic Partner(s) Beatriz Blanco-Redondo: Adhesion GPCR Discovery in Drosophila , without antibodies, no prior literature, and no established toolkit to fall back on. There was no shortcut available because there was no prior literature to build on. 2. And we have a lot of friends who don't like what they are doing. And this is very important."

Career Opportunities GPCR-specific job listings, career tips, and networking opportunities. GPCR — five live Masterclasses scheduled before summer break, examining GPCR science past the equilibrium From signaling kinetics to program building, plus two recordings moving into the on-demand library and Premium members get the complete intelligence. iPSC-Derived GPCR Models — Terry Hébert Live April 16 See what it feels like for 14 days.