Week’s Highlights: SNX9 family mediates βarrestin-independent GPCR endocytosis Valeria Robleto , Ya Zhuo , Joseph Crecelius , Sara Benzow , Adriano Marchese Cannabinoid regulation of angiotensin II-induced

Zhou, Y., et al., Multiple GPCR Functional Assays Based on Resonance Energy Transfer Sensors.  Zhao, P., et al., Activation of the GLP-1 receptor by a non-peptidic agonist. 

a database of binding sites of human G-protein coupled receptors under diverse states Fan Liu , Han Zhou , Xiaonong Li , Liangliang Zhou , Chungong Yu , Haicang Zhang , Dongbo Bu 🤩 Seriously, why would you

This week's highlight includes congrats to: Ya-Tzu Li for her contributor article titled Do You Believe

.; Zhao, S.; Shui, W.; Li, S.; Korde, A.; Laprairie, R. B.; Stahl, E. L.; Ho, J. .; Zhou, H.; Kufareva, I.; Wu, B.; Zhao, Q.; Hanson, M. A.; Bohn, L. J.; Wang, J.; Wu, M.; Katritch, V.; Zhao, S.; Kunos, G.; Bohn, L. M.; Makriyannis, A.; Stevens, R.

🚀✨ This Week’s Highlights: Congrats to: Ya-Tzu Li , our notable contributor, for her superb undergrad

disruption of natural spatial and temporal signaling patterns regulated by physiological systems (Wold and Zhou intervention for metabolic diseases such as liver disease, obesity and diabetes (Secor et al. 2021; Wold and Zhou

Zhao et al. 2019). Zhao et al. 2019) together with confocal fluorescence microscopy.

Sun D, Gao W, Hu H, Zhou S. Why 90% of clinical drug development fails and how to improve it? Shen S, Zhao C, Wu C, Sun S, Li Z, Yan W, et al. González-Maeso J, Weisstaub NV, Zhou M, Chan P, Ivic L, Ang R, et al.

and the intracellular helix 8 move outward from the receptor core to make room for the G-protein (Lu, Zhao 6P4]CCL5), a chemokine antagonist ([5P7]CCL5), and a small-molecule inverse agonist (maraviroc) (Tan, Zhu

therapeutic intervention for metabolic diseases such as liver disease, obesity and diabetes (Wold and Zhou

For example, OR4M1 was proposed to interfere with aberrant tau hyperphosphorylation (Zhao W. et. al 2013

Qian, Y., Ma, Z., Liu, C., Li, X., Zhu, X., Wang, N., Xu, Z., Xia, R., Liang, J., Duan, Y., Yin, H.,