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<< Back to podcast list Strategic Partner(s) Yao Lu (Jackie) About Yao Lu (Jackie) "Jackie is a Ph.D. small molecules for their pre-clinical efficacy and to support the design of novel therapeutics. " Yao Lu (Jackie) on the web Monash University Georgina Sweet Fellowship Authorea Dr.

During that time, I investigated the effect of lung cancer-related mutations in the GAIN domain of the GPCR About Cam Sinh Lu Cam Sinh Lu is a PhD student at Monash Institute of Pharmaceutical Sciences, Monash Cam Sinh Lu on the web LinkedIn Dr. GPCR Unlock the Full Dr.

Lukas Grätz About Dr. Lukas Grätz "After a BSc in biology and a MSc in bioinformatics, I have been working in David Gloriam's Lukas Grätz on the web Karolinska Institutet ResearchGate PubMed Dr. GPCR Unlock the Full Dr.

David Hodson Topics Covered: LUXendin probes for GLP-1R labeling across imaging modalities daLUXendin

In 2018 he joined the University of Copenhagen, where he has received an ERC Starting Grant, Lundbeck

receptors 06:30 When the field debated whether opioid receptors were even proteins 11:31 The "dumb luck

p38 signaling responses we are studying how atypical p38 controls the onset and pathogenesis of acute lung

LUXendin Family Red and far-red fluorescent GLP-1R antagonists derived from Exendin4(9–39). He is a principal architect of the LUXendin and daLUXendin probe families. Dr.

Matsunami's RTP1S chaperone, the Rho tag, and the Pluznick lab's Lucy tag — a cleavable leucine-rich kidney 19:56 The orthology problem: 1,000 mouse ORs, 350 human ones 23:08 RTP1S, the Rho tag, and the Lucy

From Curiosity to Collaboration “We decided to evaluate the multiplexing methods... and found this Luminex assay.” – Tom Sakmar After exploring several screening techniques, the lab adopted the Luminex bead-based

hear about peptide-binding GPCRs with buried or hydrophobic binding pockets, I immediately think: good luck

project, licensed to AstraZeneca (Saphnelo™ Anifrolumab) that has just received FDA approval for systemic lupus

Alexander Hauser , and Luise Wagner .

The lung's beta-2 story has been sitting in plain sight for fifty years.

development. have been engaged in GPCR cellular and clinical pharmacology as scientist or PI in neonatal lupus

examine the assay principle, validation strategy, and performance across reference antagonists and agonis Lucía degenerative, metabolic, immunological… around a third of the drugs in clinical use are GPCR ligands Lucía

Druey at NIAID/NIH, where I characterized the role of RGS4 and RGS5 in airway hyperresponsiveness and lung fascinated by the multitude of processes that are regulated/dysregulated by GPCRs and RGS proteins in the lungs

Arrestin Recruitment Detect β-arrestin recruitment with TR-FRET and luminescence assays tailored for

About this episode Originally, Annette wanted to be a medical doctor but as luck has it, she didn’t get

Frederik Leeb-Lundberg (1984) Dr. Robert Lefkowitz (1973) Dr. Lee Limbird (1973) Dr.

consequences: drugs targeting other receptors may be inadvertently activating bitter taste GPCRs in the lung

Lamichhane Discovery of CCR8 Antagonist IDOR-1136-5177 for the Treatment of Cancer Stefan Diethelm , Luboš