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Results found for "Dr. Bryan Roth"
- Purpose-Driven Opioid Research: Catherine Demery’s Academic Path
For Catherine, it became both—after years of uncertainty, pivots, and practical lab experience that grounded
- Fluorescence Polarization in GPCR Research
we have demonstrated that both radioligands and FP assays using CELT-228 A3AR fluorescent antagonist
- Neuronal Gα subunits required for the control of response to polystyrene nanoparticles in the ...
Caenorhabditis elegans was used as an animal model, and both gene expression and functional analysis
- Targeting GPCRs in the CNS: Advances in Drug Discovery Strategies
Both orphan and well-characterized GPCRs are untapped opportunities for drug development targeting CNS
- Why Opposing Processes Matter for Your Next GPCR Drug
Constitutive Activity: When Doing Nothing Still Does Something Some GPCRs simply refuse to stay quiet
- Fentanyl and Xylazine: Why Breathing Fails in Overdose
suppresses inhalation while xylazine prolongs exhalation, creating a respiratory cycle that collapses from both
- Biased Agonism at the GLP-1 Receptor: A Pathway to Improved Therapeutic Outcomes
diabetic models have shown that although exendin-P5 induces lower insulin release compared to exendin, both
- Therapeutic validation of an orphan G protein‐coupled receptor
GPR84 is a promising target to exploit and the investment in better tools to study its function in both
- Why Biotech Fundraising Fails Due to Intellectual Property Gaps
Clear intellectual property builds confidence on both sides of the biotech fundraising table Why biotech
- Illuminating GPCR Research: FRET and BRET-Based Sensors Shed Light on Cellular Signaling
Both BERKY and ONE-GO biosensors are engineered to detect the GTP-bound Gα subunit, serving as a proxy
- Exendin-4 Attenuates Remodeling in the Remote Myocardium of Rats After an Acute Myocardial ...
Both can result in a positive inotropic effect.
- How Early Strategic Decision Making Creates Alignment and Better Results
Without this clarity, everything feels important, and nothing moves decisively. 2️⃣ How will it be defined
- An overview of the compartmentalized GPCR Signaling: Relevance and Implications
As the mechanisms underlying spatial bias in GPCR signaling involve both temporal and spatial components
