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CRO partners, and GPCR experts to help teams move faster — from idea to discovery — while reducing risk

Teams that don’t understand how to detect, interpret, and exploit these mechanisms risk walking away

biotherapeutic drug discovery Novartis Kisqali® NATALEE analysis reinforces consistent reduction in risk

inhibitors, or antagonists, you must recreate the “working system” they’ll face in vivo—otherwise you risk

Assay volume control becomes a tool for risk management, translational prediction, and mechanistic insight

relying on descriptive observations—“looks like a shift,” “seems like baseline activation”—you’re leaving risk

Automates New Radioligand Therapy Production Plant Novartis’ Lutathera reduces disease progression risk

transport by CCHCR1 via direct interaction Industry News Novartis Lutathera® significantly reduced risk

a G-protein coupled receptor-related gene signature through bioinformatics analysis to construct a risk

This scarcity made the field both exciting and high-risk.

Separate effect size from time:  Use allosteric modulators to expand therapeutic index and reduce overdose risk

provide an additional check against off-target cytotoxicity or morphological changes, reducing the risk