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- 10 GPCR pharmacology lessons. Zero fluff. Launching July 1, Terry’s Corner gives you the clarity and confidence to make better decisions—starting with: • The role of pharmacology in discovery strategy • Black & Leff’s operational model—finally made practical • Binding curves, orthosteric vs allosteric function, and real vs apparent affinity • Molecular dynamics and how they guide ligand design • Why Terry built this—and how it sharpens your next move 📅 Learn anytime. New course every week. 📬 Subscribe to The Kenakin Brief → https://www.terrykenakin.com #GPCRscience #drugdiscovery #TerrysCorner #GPCRpharmacology #ligandbinding | Dr. GPCR Ecosystem
Home → Flash News → 10 GPCR pharmacology lessons. Zero fluff. s Corner gives you the clarity and confidence to make better decisions—starting with: • The role of pharmacology TerrysCorner #GPCRpharmacology #ligandbinding Published on June 30, 2025 Category Terry's Corner 10 GPCR pharmacology Corner gives you the clarity and confidence to make better decisions—starting with: 🟢 The role of pharmacology
- Distinct sub-cellular signal propagation as a component of functional selectivity
Since 2001, he holds the Canada Research Chair in Signal Transduction and Molecular Pharmacology. In addition to paradigm shifts including inverse agonism, biased signaling, and pharmacological chaperones by the attribution of many awards and distinctions including his election as a fellow of the Royal Society of Canada (2014), the Julie Axelrod award from the American Society of Pharmacology and Exerimental
- GPCR Courses
premium to get access The Practical Assessment of Signaling Bias Signaling bias is an inherent feature of pharmacology Yamina Berchiche 🔒 Premium Content Watch recording Applying Pharmacology to Drug Discovery Class 1 - Fundamentals of Pharmacology Class 2 - Characterizing Agonists Class 3 - Characterizing Antagonists and biased agonism Class 3 - Antagonist pharmacology and binding assay analysis Class 4 - New dimensions Also super-valuable for those of us learning how to teach pharmacology Anonymous Dr.
- ⚠️ Registration Deadline today! This is your last chance to register for Principles of Pharmacology II - Advanced Methods for the Optimization of Candidate Selection with Dr. Terry Kenakin. Learn more about new ligands and new GPCR behaviors that produce unique drug profiles. | Dr. GPCR Ecosystem
This is your last chance to register for Principles of Pharmacology II - Advanced Methods for the Optimization This is your last chance to register for Principles of Pharmacology II - Advanced Methods for the Optimization
- In case you haven’t heard, Dr. Terry Kenakin will soon start the course Principles of Pharmacology II - Advanced Methods for the Optimization of Candidate Selection 📖 The five-lecture series describes essential additional elements to GPCR discovery programs that extend the discovery process and increase therapeutic opportunity. | Dr. GPCR Ecosystem
Terry Kenakin will soon start the course Principles of Pharmacology II - Advanced Methods for the Optimization Terry Kenakin will soon start the course Principles of Pharmacology II - Advanced Methods for the Optimization
- Dr. Michel Bouvier | Dr. GPCR Ecosystem
Since 2001, he holds the Canada Research Chair in Signal Transduction and Molecular Pharmacology. In addition to paradigm shifts including inverse agonism, biased signaling, and pharmacological chaperones by the attribution of many awards and distinctions including his election as a fellow of the Royal Society of Canada (2014), the Julie Axelrod award from the American Society of Pharmacology and Exerimental
- Interested in learning more about signaling bias? You’re in the right place! 🙌 Join an interactive workshop with the pharmacology master Dr. Terry Kenakin and deepen your knowledge. Reading materials are already available for registered participants 👀 ✳️ Go to https://www.ecosystem.drgpcr.com/event-details-registration/the-practical-assessment-of-signaling-bias #gpcr #drgpcr | Dr. GPCR Ecosystem
🙌 Join an interactive workshop with the pharmacology master Dr. 🙌 Join an interactive workshop with the pharmacology master Dr.
- Exploring the combination of molecular simulation, pharmacological assays, and NMR to reveal the molecular mechanism of biased activation at the vasopressin V2 receptor. Did you know that we work hard to bring you the most recent GPCR News, weekly? Catch up today in the Ecosystem using your free site membership! | Dr. GPCR Ecosystem
Home → Flash News → Exploring the combination of molecular simulation, pharmacological assays, and NMR Published on December 10, 2024 Category GPCR Weekly News Exploring the combination of molecular simulation, pharmacological
- From aspiring doctor to GPCR scientist! 🔬In this episode, Ian Chronis shares his journey from med school dreams to a PhD in pharmacology, diving into the fascinating world of receptor signaling. Can you guess what’s his favorite GPCR? ✅ Hear his response: Ep 164 with Dr. Ian Chronis #SciencePodcast #GPCR #PhDLife #DrGPCR | Dr. GPCR Ecosystem
🔬In this episode, Ian Chronis shares his journey from med school dreams to a PhD in pharmacology, diving 🔬In this episode, Ian Chronis shares his journey from med school dreams to a PhD in pharmacology, diving
- Science isn't always about eureka moments—sometimes it's about steady progress. In our latest Dr. GPCR Podcast episode, Ian Chronis shares his top aha moments, from learning the hard way about gel electrophoresis to discovering the hidden complexities of GPCR signaling. ✅ https://buff.ly/FTB69y9 #GPCR #DrGPCR #SciencePodcast #Pharmacology | Dr. GPCR Ecosystem
. ✅ https://buff.ly/FTB69y9 #GPCR #DrGPCR #SciencePodcast #Pharmacology Published on April 22, 2025 Category the hidden complexities of GPCR signaling. ✅ https://buff.ly/FTB69y9 #GPCR #DrGPCR #SciencePodcast #Pharmacology
- 💡 GPCR drug development doesn’t have to be a mystery! Learn from Dr. Terry Kenakin in this 4-week immersive course covering ligand development & pharmacology. 🔹 What you’ll learn: ✅ Drug Development Basics – Absorption, metabolism, PK principles ✅ Clearance & Distribution – Renal & hepatic clearance, key pharmacokinetics ✅ PK-PD Modeling – Predicting drug behavior, non-linear PK ✅ Early Drug Safety – Toxicity risks & drug interactions 📌 Spots are filling fast! Sign up today 👉 Development of GPCR Ligands as Therapeutic Drugs | Dr. GPCR Ecosystem #GPCR #DrGPCR #Pharmacology #Biotech #DrugDiscovery | Dr. GPCR Ecosystem
Terry Kenakin in this 4-week immersive course covering ligand development & pharmacology. 🔹 What you GPCR Ecosystem #GPCR #DrGPCR #Pharmacology #Biotech #DrugDiscovery Published on March 8, 2025 Category Terry Kenakin in this 4-week immersive course covering ligand development & pharmacology. 🔹 What you GPCR Ecosystem #GPCR #DrGPCR #Pharmacology #Biotech #DrugDiscovery Previous Next Recent Articles Decoding
- Behind every great discovery is a great question 🚀 Dr. Dmitry Veprintsev shares how asking the right GPCR questions and dreaming big have shaped his work, in the latest Dr. GPCR podcast episode. If you’re passionate about GPCRs and drug discovery, this episode is a must-listen! ✳️Listen at Ep 163 with Dr. Dmitry Veprintsev #DrGPCR #GPCRPodcast #Biotech #Pharmacology #GPCRScience | Dr. GPCR Ecosystem
Dmitry Veprintsev #DrGPCR #GPCRPodcast #Biotech #Pharmacology #GPCRScience Published on April 10, 2025 Dmitry Veprintsev #DrGPCR #GPCRPodcast #Biotech #Pharmacology #GPCRScience Previous Next Recent Articles
- terrys corner no fluff pure insight | Dr. GPCR Ecosystem
✨ We've poured our passion for pharmacology into creating this essential resource, designed to meet you Ready to: Strengthen your pharmacology fundamentals? Terry's Corner helps you make better decisions through better pharmacology. Enroll now: https://www.terrykenakin.com #pharmacology #GPCRscience #drugdiscovery #TerrysCorner #biotechtraining
- C-Principles of Pharmacology in Drug Discovery 1 | Dr. GPCR Ecosystem
Principles of Pharmacology in Drug Discovery I Techniques for Effective Lead Optimization of Candidate still are the most prolific and fertile therapeutic drug targets; this course describes the essential pharmacologic In general, registrants will receive a comprehensive understanding of the unique science of pharmacology Registrants will learn: Essentials of measuring pharmacologic activity of ligands (affinity, efficacy Also super-valuable for those of us learning how to teach pharmacology Anonymous What would you like
- irreversible drugs post 1 | Dr. GPCR Ecosystem
Join Terry’s Corner and master irreversible pharmacology for modern discovery programs. Unlike reversible ligands, their impact can persist long after the compound is gone — creating durable pharmacological Those who master kinetic pharmacology set the pace. 🟢 Join Terry’s Corner and sharpen your pharmacology GPCR Ecosystem #GPCR #DrGPCR #Pharmacology #DrugDiscovery #MedicinalChemistry #PKPD #ReceptorKinetics
- The registration deadline for the 1-day workshop “The Practical Assessment of Signaling Bias” is TOMORROW! ⏰ Save your spot in a class with the Master of Pharmacology Dr. Terry Kenakin, and get 25% off with your Premium Membership. An advanced lecture, hands-on exercises, one private call with the professor, and more! ✳️Click here https://www.ecosystem.drgpcr.com/event-details-registration/the-practical-assessment-of-signaling-bias #gpcr #drgpcr | Dr. GPCR Ecosystem
⏰ Save your spot in a class with the Master of Pharmacology Dr. ⏰ Save your spot in a class with the Master of Pharmacology Dr.
- Generic tools won’t solve tomorrow’s drug discovery challenges. That’s why Celtarys designs custom fluorescent probes for every target, built for real pharmacology, not just convenience. With Dr. GPCR and Celtarys joining forces, expect more visibility, more precision, and more scientific impact. 🚀 Get to know our media partner: https://www.ecosystem.drgpcr.com/celtarys-research-dr-gpcr-ecosystem #GPCRdrugDiscovery #GPCRecosystem #CustomLigands | Dr. GPCR Ecosystem
That’s why Celtarys designs custom fluorescent probes for every target, built for real pharmacology, That’s why Celtarys designs custom fluorescent probes for every target, built for real pharmacology,
- Can we preserve opioid pain relief without the side effects? 🔬 On Ep.166 of the Dr.GPCR Podcast, Ben Clements shares how positive allosteric modulators (PAMs) at the mu-opioid receptor could revolutionize treatment —with a 10x boost in methadone efficacy. Tune in for a masterclass on translational pharmacology, curiosity-driven science, and meaningful mentorship. 🎧 Full episode: Ep 166 with Dr. Ben Clements #GPCRresearch #DrGPCR #GPCRpodcast #OpioidPharmacology #DrugDiscovery | Dr. GPCR Ecosystem
Tune in for a masterclass on translational pharmacology, curiosity-driven science, and meaningful mentorship Tune in for a masterclass on translational pharmacology, curiosity-driven science, and meaningful mentorship
- 🚀 New Learning Opportunities at Dr.GPCR University! Expand your GPCR expertise with exclusive workshops, interactive courses, and an on-demand library—all in one place! ✅ Register for upcoming sessions ✅ Access expert-led content anytime ✅ Enjoy premium benefits & exclusive resources 📢 Don’t miss out—start your learning journey today! 🔗 https://www.ecosystem.drgpcr.com/gpcr-courses #GPCR #DrGPCR #LifelongLearning #drugdiscovery #pharmacology | Dr. GPCR Ecosystem
🔗 https://www.ecosystem.drgpcr.com/gpcr-courses #GPCR #DrGPCR #LifelongLearning #drugdiscovery #pharmacology 🔗 https://www.ecosystem.drgpcr.com/gpcr-courses #GPCR #DrGPCR #LifelongLearning #drugdiscovery #pharmacology
- Dr. Graciela Pineyro | Dr. GPCR Ecosystem
Graciela Pineyro is a professor of pharmacology at the department of pharmacology and physiology of the She has done extensive work on the molecular pharmacology of opioid receptors and is currently focusing on the pharmacology of cannabinoids in the context of pain.
- New Episode Alert! 🎙️ Ep. 163 of the Dr. GPCR Podcast is here! 🚀 This time, we sit down with Dr. Dmitry Veprintsev to discuss the importance of asking the right GPCR questions. Whether you're a researcher, student, or GPCR enthusiast, this episode is packed with insights that will challenge how you think about your experiments. ✳️Tune in at https://www.ecosystem.drgpcr.com/dr-gpcr-podcast/ep-163-with-dr.-dmitry- #DrGPCR #GPCRPodcast #Pharmacology #DrugDiscovery #Biotech #GPCRs | Dr. GPCR Ecosystem
-dmitry- #DrGPCR #GPCRPodcast #Pharmacology #DrugDiscovery #Biotech #GPCRs Published on April 1, 2025 -dmitry- #DrGPCR #GPCRPodcast #Pharmacology #DrugDiscovery #Biotech #GPCRs Previous Next Recent Articles
- irreversible drugs post 3 | Dr. GPCR Ecosystem
Explore Terry’s Pharmacology Vault. Published on October 27, 2025 Category Terry's Corner Receptor pharmacology has evolved. These lessons bridge molecular pharmacology with real-world design strategy, giving discovery teams the GPCR Ecosystem #GPCR #DrGPCR #Pharmacology #DrugDiscovery #Kinetics #ReceptorPharmacology #MedicinalChemistry
- ama session sept 18 post 2 | Dr. GPCR Ecosystem
Discover what 40+ years of pharmacology reveal. Terry’s Corner was built to make advanced pharmacology practical: a space where scientists don’t just Read More → https://www.ecosystem.drgpcr.com/post/accelerating-gpcr-drug-discovery-what-40-years-of-pharmacology-reveal ✳️ Next AMA Session: October 30 | 12–1 PM EST #GPCR #DrGPCR #Pharmacology #DrugDiscovery #AllostericModulation
- Dr. Samuel Hoare | Dr. GPCR Ecosystem
He then moved to the National Institute of Mental Health, researching pharmacological mechanisms of Class Today, Sam is a pharmacology data analyst and the founder of Pharmechanics LLC , a consultancy and data pharmacologist, he consults with numerous pharma and biotechs in understanding and applying in vitro pharmacology Hoare was a pharmacology leader in the pharmaceutical industry for 15 years at Neurocrine Biosciences Sam is known for demystifying complicated and newly-emerging pharmacology concepts, enabling them to
- ⏳ In case you haven’t heard—registration for “Development of GPCR Ligands as Therapeutic Drugs” closes March 18th! If you’re working on GPCR drug discovery, you know that finding a promising candidate is just the start. A drug must also: ✅ Be absorbed into the body ✅ Reach the right target ✅ Stay long enough to be effective ✅ Cause no harm 📢 Spots are limited—register by March 18th! 👉 Development of GPCR Ligands as Therapeutic Drugs | Dr. GPCR Ecosystem #GPCR #DrGPCR #Pharmacology #Biotech #DrugDiscovery | Dr. GPCR Ecosystem
GPCR Ecosystem #GPCR #DrGPCR #Pharmacology #Biotech #DrugDiscovery Published on March 10, 2025 Category GPCR Ecosystem #GPCR #DrGPCR #Pharmacology #Biotech #DrugDiscovery Previous Next Recent Articles
- Dr. Graciela Pineyro | Dr. GPCR Ecosystem
Graciela Pineyro’s love for GPCR pharmacology started in Uruguay where she first worked on the serotonin This interest in research and pharmacology took Graciela to Canada where she stayed ever since she arrived Graciela has done extensive work on the molecular pharmacology of opioid receptors, exploring their signaling Today, Graciela and her team’s efforts are directed towards the characterization of the pharmacological
- Dr. Terry Kenakin | Dr. GPCR Ecosystem
obtaining a BSc in chemistry at the University of Alberta Edmonton Canada, Terry received his Ph.D. in Pharmacology Since 2011, Terry works at the Department of Pharmacology at the University of North Carolina School His interests are in receptor pharmacology, allosteric protein function, and drug discovery. Dr. Terry Kenakin on the web LinkedIn UNC Department of Pharmacology Amazon ResearchGate Pubmed . Dr.
- ama session sept 18 post 1 | Dr. GPCR Ecosystem
Level up your pharmacology toolkit. 1 Ask-Me-Anything Session - Sept 18 - Trailer Published on October 28, 2025 Category Terry's Corner Pharmacology early—before your program locks into costly pathways Rethink legacy screening frameworks through modern pharmacology #GPCR #DrGPCR #Pharmacology #DrugDiscovery #Biotech #AllostericModulation #Kinetics #AssayDevelopment
- 🎧 Why Does GPCR Location Make All the Difference? GPCR location within the cell can change everything: function, pharmacology, and even drug response. In Ep.162 of the Dr.GPCR Podcast, Dr. Gabriele Kockelkoren dives into: 🔬 How GPCR trafficking shapes signaling outcomes 🚀 Career insights from the lab to the broader biotech world This episode is packed with knowledge for scientists, drug hunters, and anyone fascinated by GPCRs! 🎙️ Listen now https://buff.ly/fYZ1tSq #DrGPCR #GPCR #DrugDiscovery #Pharma #Biotech #SciencePodcast ✅ Tune in today! | Dr. GPCR Ecosystem
GPCR location within the cell can change everything: function, pharmacology, and even drug response. GPCR location within the cell can change everything: function, pharmacology, and even drug response.
- Dr. Stephen Ferguson | Dr. GPCR Ecosystem
Brian Collier in the Department of Pharmacology and Therapeutics at McGill University (1994). He has also received both Junior (2001) and Senior (2005) investigator awards from the Pharmacological Society of Canada.
