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Burger , Arthur Christopoulos , David M.

reveals unexpected differences in downstream pathway activation Chiara D Mancinelli, Joshua Levitz, David

José Labandeira-García , Rafael Franco Endomembrane GPCR signaling: 15 years on, the quest continues Davide

E. Cardona et al. 2008). E. Cardona et al. 2008).

Gioé-Gallo C, Mallo-Abreu A, Brea J, Loza MI, García-Rey A, García-Mera X, Gutiérrez-de-Terán H, Sotelo E.

This Week’s Highlights: G protein-coupled receptor (GPCR) pharmacogenomics Miles D Thompson , David

Working closely with Professor David Parker of Durham University, Trinquet’s group cracked the scaffold

B., Mehrota, E., Grimes, P. R., ... & Manglik, A. (2024).

Physiology or Medicine was awarded jointly to Ragnar Arthur Granit, Haldan Keffer Hartline, and George David E. Nobel Prize: Three Named for Medicine, Physiology Award. Ekaterini Tiligada, C., Tiligada, E. & Ennis, M.

Curr Issues Mol Biol. 2024 Oct 19;46(10):11646-11664. doi: 10.3390/cimb46100691   Navarro G, Sotelo E,

Terence E.

Structure-guided design of a peripherally restricted chemogenetic system Hye Jin Kang , Brian E Krumm

molecular dynamics simulations Leukotriene B4 receptor 1 (BLT1) activation by leukotriene B4 (LTB4) and E

Encoded Fluorescent Indicators Design of an effective small expression tag to enhance GPCR production in E.

B., Mehrotra, E., Patrick Rockefeller Grimes, Zahm, A. M., Trinidad, D. D., English, J.

Goyet, E., et al., Fast and high resolution single-cell BRET imaging. 

Reiter, E., Ahn, S., Shukla, A.K., and Lefkowitz, R.J. (2012).

GPCRs are divided into six classes based on amino acid sequence similarities, but only four of the classes

Gq, Gs, Gi, G12 and G13 engagements with GPR110 reveals details of G-protein engagement, including a dividing

affects the recognition of CCL21 but not CCL19, interfering with dendritic cell trafficking (Kiermaier E

This may be broadly divided into studies focused on obtaining detailed molecular information in the intracellular

Thanks to the unique linker structure we obtain, which can be divided into three differentiated parts

Wodak SJ, Paci E, Dokholyan NV, Berezovsky IN, Horovitz A, Li J, et al. Pearce A, Redfern-Nichols T, Wills E, Rosa M, Manulak I, Sisk C, et al.

former students now work in industry, where their ability to bridge the computational-experimental divide

Methods: Rats were divided into sham, sham + Exendin-4 (10 μg/day, i.p), MI, and MI + Exendin-4.

E.; Miller, L. J.

The cytotoxic drug Monomethyl auristatin E (MMAE) was used alone or conjugated to either the native CCL5