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Results found for "David Minh"
- Ever Wondered How Drugs Are Discovered?
drugs, breaking down the science into accessible, engaging insights for early learners and curious minds
- The Chemistry of Confidence: Aha Moments That Shape Scientific Careers
Choosing not to overthink major career decisions, because as she puts it: “A lot of friends of mine
- Is Your GPCR Drug Discovery Program Built for Breakthroughs or Breakdowns?
You can have the most brilliant minds and cutting-edge assays, but if your science isn't continuously believe we don't have time to build better systems, but in reality, our most brilliant and expensive minds
- Mapping Motion: Intermediate States, Deorphanization & Discovery
GPCR Colleagues & Curiosity-Driven Minds, We’re starting with exciting Dr.
- GPCR Collaboration: From Models to Medicine
effective discovery programs are structured like Carlsson’s: modeling designed with downstream chemistry in mind And he prioritizes shared purpose , designing each project with the next experiment in mind.
- Beyond Clearance: The Strategic Power of Irreversible Drug Binding
Designing Strategically with Irreversible Drug Binding in Mind When irreversible mechanisms are designed If you’re not designing with persistent enzyme interactions in mind, you’re building risk into your molecule
- Endosomal parathyroid hormone receptor signaling
This mini-review discusses recent insights into the mechanisms of PTHR endosomal signaling and its physiological
- Terry’s Corner, Celtarys' Leap, and the $7B GPCR Horizon
Hello GPCR Minds, This week, you'll learn all about Terry’s Pharmacology Corner, your new learning
- 📰 GPCR Weekly News, July 1 to 7, 2024
Alejandra Tomas, et al. for their research on Engineered mini-G proteins block the internalization of agonism The roles of RGS proteins in cardiometabolic disease GPCR Binders, Drugs, and more Engineered mini-G
- Illuminating GPCR Research: FRET and BRET-Based Sensors Shed Light on Cellular Signaling
NanoBRET ligand binding [5]), effector protein recruitment assays (e.g G protein recruitment assay [6], mini-G Wan, Q., et al., Mini G protein probes for active G protein-coupled receptors (GPCRs) in live cells.
- PH-Binding Motif in PAR4 Oncogene: From Molecular Mechanism to Drug Design
Pc(4-4), a lead backbone cyclic peptide, was selected out of a mini-library, directed toward PAR2&4 PH-binding
- The Imprecision Problem: Why Your GPCR Drug Discovery Program Is Off-Track Before It Even Starts
Brilliant minds doing low impact work is not a strategy. It’s a slow-motion car crash.
- Reflections on My PhD Journey: Lessons Learned
These mini "journal clubs" kept me informed about the latest research and sharpened my critical thinking
- How GPCR Spatial Signaling Sparked a Scientific Journey
Mini Timeline Summer Project — Unexpected spark PhD at Monash — From curiosity to expertise Cambridge
- The sixth transmembrane region of a pheromone G-protein coupled receptor, Map3, is implicated in ...
The fission yeast Schizosaccharomyces pombe has two mating types, Plus (P) and Minus (M).
- How GPCR Collaboration Built an Innovation Engine
Mini Timeline: How the Model Evolved Year 0 — Shared lab space established; PI buy-in secured Year 2
- GPCR Drug Discovery at Discovery on Target: Why This Track Is About More Than Receptors
In the run-up to the conference, our founder Yamina Berchiche is speaking with some of the brilliant minds
- 📰 GPCR Weekly News, August 7 to 13, 2023
more Tri-part NanoLuc as a new split technology with potential applications in chemical biology: a mini-review
- 📰 GPCR Weekly News, October 23 to 29, 2023
Hi there GPCR minds! Join us for a deep dive into the world of GPCRs.
- What's Going On with GPCRs?! Find Out in This Week's Update! ⦿ Nov 4 - 10, 2024
Hey there, curious minds! Want to know what’s buzzing in the world of GPCRs? This Week’s Highlights: Harnessing Deep Mutational Scanning for Enhanced Drug Discovery Cam Sinh Lu
- 📰 GPCR Weekly News - January 9 to 15, 2023
approved for first-line treatment The Lundbeck Foundation is awarding DKK 174 million in grants to seven ‘mind-bending
- The Hidden Driver of GPCR Drug Success: Why Target Residence Time Matters More Than You Think
Why contribute: Join a global, like-minded GPCR community.
- 📰 GPCR Weekly News, August 21 to 27, 2023
Hi there GPCR minds! Join us for a deep dive into the world of GPCRs. This week's highlights: Dr.
- How to Avoid the Most Common Gaps in Your Biotech Pitch
Here’s the uncomfortable truth: 👉 People make up their minds in the first few seconds.
- How Understanding Intracellular Drug Access Can Transform Your GPCR Drug Discovery Program
Connect with experts: Join a community of like-minded field-experts dedicated to improving our collective
- 📰 GPCR Weekly News, February 27 to March 5, 2023
Keep in mind that you can always change your email preferences in your account settings.
- FDA Approval Is a Strategy Obstacle, Not a Paperwork Problem
justification , not just efficacy You plan manufacturing processes with scale-up and CMC documentation in mind
- 📰 GPCR Weekly News, October 30 to November 4, 2023
with decitabine in relapsed or refractory acute myeloid leukemia Methods & Updates in GPCR Research Mining
- GPCR Weekly Whirlwind: Top Receptor Highlights from Sep 30 - Oct 6, 2024!
Get ready to dive into some discoveries and mind-blowing breakthroughs with us! This Week’s Highlights: Congrats to: Our contributor, Cam Sinh Lu , who has just released an incredible with his team: Targeted Drug Design through GPCR Mutagenesis: Insights from β2AR China M Payne , Cam Sinh
- New role of β-arrestins in MOR signaling
With this in mind one of the proposals is to take advantage of biased agonism, i.e. when the same receptor


















