Search Results

The GPCR Data Dilemma: The Lego Bucket Problem I've seen promising GPCR programs generate massive volumes I call this the Lego Bucket Problem . You have the data, but not the definitive direction. GPCR, we've built a global hub connecting over 1,300 GPCR scientists dedicated to this field. My Consulting Philosophy This practice is built on three core values: Scientific Integrity:  Every Collaborative Partnership:  I embed, contribute, and build solutions hand-in-hand with your team.

I call it the Lego Bucket Problem : You’ve got CRO output, internal assay data, maybe even some promising Not possible when nothing’s built to surface the right  insights early. That’s Why I Built Yamina’s Consulting Corner This is not “advising.” challenges firsthand, identify roadblocks faster , and i mplement solutions from within , ensuring genuine buy-in Operational Discipline ✔️ Collaborative Partnership Let’s Get Your GPCR Program Moving Again Whether you’re building

While others pivoted, Sokhom went deeper: refining assays, exploring signaling bias, and building a robust A Career Built on Consistency From CGRP receptor antagonists at BMS to opioid receptor research at Alkermes

Welcome Back, Discovery Drivers   Terry’s Corner is live, on-demand pharmacology built for drug discovery That’s the Lego Bucket Problem.   

HT1A agonist, delivers selective pain relief in preclinical models Dr.GPCR Updates Terry’s Corner  – Build It’s a story of leadership, scientific rigor, and tools built for the needs of modern discovery teams CXCR4 signaling promotes terminal erythropoiesis  through nuclear translocation and perinuclear calcium bursts

importance of genuinely listening to researchers: understanding the biological question first, then building

Explore her path from postdoc to platform builder.  

Building for the Future The Sakmar lab built a system to meet that need: Dual-epitope tagged constructs

Budded baculoviruses (BBV) have a high receptor concentration as well as being homogenous in size, which Using the FA method, CELT-419 binding affinity and kinetics were determined using budded baculovirus An equivalent volume of assay buffer was added to association controls (filled dark blue circles). Displacement of CELT-419 by different concentrations of Butaclamol  (A)  and PL-384  (B)  at different M.; Bucolo, C.; Platania, C. B. M.; Salomone, S.; Drago, F.

With the help of Luminex technology and collaborators at SciLifeLab in Sweden , the lab built a multiplex GPCR biology is approached : Study known & orphan GPCRs Identify new accessory protein interactions Build models Validate antibodies for hard-to-study receptors And most importantly, it’s free to academics , built

Methods for the Optimization of Candidate Selection  – Master GPCR behavior beyond second messengers   Build

But as Ben points out, burnout is real, and it doesn’t make you better.

searching for the "right" postdoc or PhD lab, this episode is a playbook for what to look for and what to build

Rock your favorite design, spark conversations in the lab, and help power everything we build—one mug

Every insight you share helps us build a smarter, more supportive GPCR community—together.

GPCR Updates   Techniques for Effective Lead Optimization – Master pharmacology on demand   Build stronger

Butlen-Ducuing F, Pétavy F, Guizzaro L, Zienowicz M, Salmonson T, Haas M, et al. Truong ME, Bilekova S, Choksi SP, Li W, Bugaj LJ, Xu K, et al. Franzen MM, Alder ML, Dreyer F, Köpp W, Buchholz MB.

GPCR, we believe the same principle applies to building a better experience  for our online community

Hello, hello GPCR Buddies! It's starting to look a lot like Christmas at Dr. GPCR! We are bursting with pride in sharing it with you, and we sincerely want to thank you for your support

Buckle up as we time-hop through this week's GPCR escapade!

approach requires careful planning, but it saves you from the frustration of ambiguous data and helps build

GPCR community members Build connections with other GPCR fans :) So much more to come! Narcolepsy and IH Crinetics Pharmaceuticals Reports Third Quarter 2024 Financial Results and Provides Business

on Germline mutations in a G protein identify signaling cross-talk in T cells Victoria Saca , Colin Burdette *Lessons are every Thursday at 10 AM EST. 🔥 Why You Should Enroll Now: Budget-Friendly & Distinctive

Burger , Arthur Christopoulos , David M. 🚨 Hurry to reserve your spot for the Principles of Pharmacology I & II BUNDLE before the Early

The Principles of Pharmacology I & II BUNDLE is your key to mastering the field. Affordable & Unique Learning Experience Our budget-friendly courses offer a unique approach to mastering

The Principles of Pharmacology I & II BUNDLE is your golden ticket to mastering the field. Affordable & Unique Learning Experience Dive deep into pharmacology with our budget-friendly courses 26th to September 1st, 2024 Industry News GPCR-RAMP Interactome Maps Could Help Drug Developers Find Buried

Don’t miss this incredible opportunity to immerse yourself in the  Principles of Pharmacology I & II BUNDLE

Advanced Methods for the Optimization of Candidate Selection Dates: October 3rd to 31st, 2024 Overview: Building

Additionally, transparency in AI models and their operations is crucial for building trust and allowing

era of making sure that historically excluded demographics are finally included, this represents a building When in Mexico City from 23-25 October, here is my bucket list of the 3 things that people should absolutely