Bryan L Roth study on Illuminating the understudied GPCR-ome Save the dates: February 8 - 29: Dr.

Binding of Stalk-derived Peptide Agonists GPCR Binders, Drugs, and more In silico exploration of 4(α-l-rhamnosyloxy

Structural and Molecular Insights into GPCR Function Endogenous l- to d-amino acid residue isomerization

 Marion Lanier ,   Brian K Shoichet ,  Esther Martinborough ,  Jonathan F Fay ,  Can Cao ,   Bryan L

L., & Fowler, D. M. (2011). B., Mehrotra, E., Patrick Rockefeller Grimes, Zahm, A. M., Trinidad, D. D., English, J.

Zhang, and L. Ma. 2008.

HDAC3 inhibition to activate autophagy in head kidney macrophages from turbot (Scophthalmus maximus L.

Sakmar, Debbie L. Hay, Lukas Grätz, and more. Check out some of the latest GPCR discoveries below!

Endogenous l- to d-amino acid residue isomerization modulates selectivity between distinct neuropeptide

and dopamine D2 receptor is required for selective potentiation of dopamine D2 receptor function by L-

Katharina Grotsch, Bryan L Roth, Valery V Fokin  et al. for their research on Virtual Screening of a

L., & Garcia, K. C. (2015). Structural biology.

calculated using the Cheng–Prusoff equation, with CELT-331 parameters fully reported (Kd ≈ 160 nM; [L]

doi.org/10.1124/jpet.112.201616 Violin, J.D., DeWire, S.M., Yamashita, D., Rominger, D.H., Nguyen, L.

β-arrestins and how this complex operates on the plasma membrane of living cells was the goal achieved by Jak Grimes in-depth-molecular-profiling-of-an-intronic-gnao1-mutant-as-the-basis-for-personalized-high-throughput-drug-screening References Grimes L., Stepniewski, T.

Signalling 4 (RGS4) negatively modulates nociceptin/orphanin FQ opioid receptor signalling: Implication for l-Dopa-induced

In the skin, OR51E2 was shown to play a role in human melanocyte homeostasis (Gelis L. et. al 2016) and

was performed highlighted a new hydrophobic conserved motif composed of phenylalanine (F)/leucine (L)

L.