Search Results
Results found for "Yang Du"
- A positive Allosteric Modulator of M1 Acetylcholine Receptors Improves Cognitive Deficits in Male and Female Alzheimer’s Mice
Event Next Event Great Lakes GPCR Retreat and Club des Récepteurs à Sept Domaines Transmembranaires du Québec Great Lakes GPCR Retreat and Club des Récepteurs à Sept Domaines Transmembranaires du Québec
- Biochemical Mechanisms Underlying Location Bias in GPCR Signaling
During his doctoral work in the lab of Prof. He then joined the Internal Medicine Residency training program at Duke University Medical Center. During his Cardiology fellowship, he trained in the lab of Dr. Robert J. Event Next Event Great Lakes GPCR Retreat and Club des Récepteurs à Sept Domaines Transmembranaires du Québec Great Lakes GPCR Retreat and Club des Récepteurs à Sept Domaines Transmembranaires du Québec
- GPCR Retreat | Dr. GPCR Ecosystem
GPCR Retreat is an annual joint meeting with the Club des récepteurs à Sept Domaines Transmembranaires du Retreat partnered with the annual symposium of the Club des Récepteurs à Sept Domains Transmembranaires du
- Atypical Structure and Function of Typical Chemokine Receptors
Event Next Event Great Lakes GPCR Retreat and Club des Récepteurs à Sept Domaines Transmembranaires du Québec Great Lakes GPCR Retreat and Club des Récepteurs à Sept Domaines Transmembranaires du Québec
- Interaction with the cell adhesion molecule NEGR1 affects mGluR5 cell signalling
Event Next Event Great Lakes GPCR Retreat and Club des Récepteurs à Sept Domaines Transmembranaires du Québec Great Lakes GPCR Retreat and Club des Récepteurs à Sept Domaines Transmembranaires du Québec
- Distinct sub-cellular signal propagation as a component of functional selectivity
Ph.D. in Neurological Sciences at the same university in 1985, he completed a post-doctoral fellow at Duke Event Next Event Great Lakes GPCR Retreat and Club des Récepteurs à Sept Domaines Transmembranaires du Québec Great Lakes GPCR Retreat and Club des Récepteurs à Sept Domaines Transmembranaires du Québec
- Unveiling Non-Canonical Functions for Gαq Signaling Pathways
During this period and her doctoral thesis, she has deepened the regulatory mechanisms of GPCR signaling Event Next Event Great Lakes GPCR Retreat and Club des Récepteurs à Sept Domaines Transmembranaires du Québec Great Lakes GPCR Retreat and Club des Récepteurs à Sept Domaines Transmembranaires du Québec
- Inhibition of Relaxin Autocrine Signaling Confers Therapeutic Vulnerability in Ovarian Cancer
postdoctoral studies with Allan Bernstein at the Lunenfeld Research Institute in Toronto and with Patrice Dubreuil Event Next Event Great Lakes GPCR Retreat and Club des Récepteurs à Sept Domaines Transmembranaires du Québec Great Lakes GPCR Retreat and Club des Récepteurs à Sept Domaines Transmembranaires du Québec
- "Have a nice weekend, and I'll see you tomorrow!": RAMP-interacting GPCR Pathways
Caron received a BS in Biology and BA in Philosophy at Emory University and a PhD at Duke University Event Next Event Great Lakes GPCR Retreat and Club des Récepteurs à Sept Domaines Transmembranaires du Québec Great Lakes GPCR Retreat and Club des Récepteurs à Sept Domaines Transmembranaires du Québec
- Trainee Symposium I
During his graduate studies, Emile is interested in characterizing novel G protein-coupled receptors Event Next Event Great Lakes GPCR Retreat and Club des Récepteurs à Sept Domaines Transmembranaires du Québec Great Lakes GPCR Retreat and Club des Récepteurs à Sept Domaines Transmembranaires du Québec
- GPCR Retreat Committee 2023 | Dr. GPCR Ecosystem
Mario Tiberi Great Lakes GPCR Retreat and Club des Récepteurs à Sept Domaines Transmembranaires du Québec
- Interrogating Multiscale Receptors Functions in Space
a Ph.D. in Neurological Sciences from McGill University and completed his post-doctoral training at Duke Event Next Event Great Lakes GPCR Retreat and Club des Récepteurs à Sept Domaines Transmembranaires du Québec Great Lakes GPCR Retreat and Club des Récepteurs à Sept Domaines Transmembranaires du Québec
- Trainee Symposium II
During my short academic journey, I was awarded the Young Investigator Transdisciplinary Research Award Event Next Event Great Lakes GPCR Retreat and Club des Récepteurs à Sept Domaines Transmembranaires du Québec Great Lakes GPCR Retreat and Club des Récepteurs à Sept Domaines Transmembranaires du Québec
- GPCR Retreat 2023 | Dr. GPCR Ecosystem
Protein-Coupled Receptor Retreat held jointly with the Club des Récepteurs à Sept Domaines Transmembranaires du Organizing Committee Great Lakes GPCR Retreat and Club des Récepteurs à Sept Domaines Transmembranaires du
- GPCR Retreat Logo Contest | Dr. GPCR Ecosystem
your logo HERE <--- Great Lakes GPCR Retreat and Club des Récepteurs à Sept Domaines Transmembranaires du
- GPCR Retreat Registration 2023 | Dr. GPCR Ecosystem
Registration includes: Full Retreat Access All meals (please note that we will ask for dietary restrictions during Retreat, click here Great Lakes GPCR Retreat and Club des Récepteurs à Sept Domaines Transmembranaires du
- Dr. Bianca Plouffe | Dr. GPCR Ecosystem
In 2006, Bianca obtained a Doctoral Scholarship from the Fonds de Recherche du Québec en Santé.
- Anything BUT GPCRs with Dr. Mikel Garcia-Marcos | Dr. GPCR Ecosystem
Mikel Garcia-Marcos "I was trained as a biochemist and molecular biologist during my Ph.D (2005) in Spain and Belgium, and subsequently as a cell biologist during my postdoc (2006-2011) with Dr. To achieve this goal, we use a wide range of established approaches (biochemistry, cell biology, genetics
- Signals, pH, and Discovery : Cracking GPCR Mysteries with Dr. Ian Chronis | Dr. GPCR Ecosystem
This dual functionality—environmental sensing and compartment-specific signaling—offers a new layer of titles, with Yamina suggesting "Ancient Greek Chemistry and GPCRs"—a nod to Ian’s heritage and the wide-ranging
- terrys corner model drug response | Dr. GPCR Ecosystem
Terry's Corner What if a single experimental snapshot could predict an entire in vivo drug profile in a range
- This new study reveals how the conformation of parathyroid hormone (PTH) and the C-terminal helix α5 of Gα regulate the selective coupling of PTH1R to Gs or Gq. Through Cryo-EM and single-cell experiments, the authors show differences in binding affinity, duration, and strength. Subscribe to the Dr. GPCR Newsletter 📰 and get the latest GPCR News delivered to your inbox ➡️ https://www.ecosystem.drgpcr.com/structural-and-molecular-insights-into-gpcr-function/allosteric-mechanism-in-the-distinctive-coupling-of-gq-and-gs-to-the-parathyroid-hormone-type-1-receptor #gpcr #drgpcr | Dr. GPCR Ecosystem
Through Cryo-EM and single-cell experiments, the authors show differences in binding affinity, duration Through Cryo-EM and single-cell experiments, the authors show differences in binding affinity, duration
- What if you could map GPCR-RAMP interactions across the entire superfamily in a single experiment? That’s precisely what Dr. Kotliar from the Sakmar lab made possible! In Ep.167 of the Dr. GPCR Podcast, we chat with Drs. Tom Sakmar and Ilana Kotliar about how their lab developed: A multiplexed Luminex assay to screen hundreds of interactions at once A 220-clone DUET-tagged GPCR library, available on Addgene An online interface to search GPCR-RAMP data and antibody validations This is open-access science at its best, built for the GPCR research community. ✳️ Listen to the episode: Ep 167 with Drs. Tom Sakmar & Ilana Kotliar #GPCRresearch #DrGPCRecosystem #GPCRdrugdiscovery #GPCRtrainingprogram #GPCRpodcast | Dr. GPCR Ecosystem
their lab developed: A multiplexed Luminex assay to screen hundreds of interactions at once A 220-clone DUET-tagged their lab developed: A multiplexed Luminex assay to screen hundreds of interactions at once A 220-clone DUET-tagged
- Started in medicinal chemistry. Got hooked on ligand design. Dr. Maria Majellaro didn’t plan to run a biotech company. A thesis project, a mentor’s advice, and a leap during the pandemic changed everything. Now she’s leading Celtarys, building custom fluorescent probes, and partnering with Dr. GPCR to support assay development worldwide. Meet Celtarys and learn more about its leading work on ligand-linker-fluorophore chemistry 🚀 ✳️ Listen now: https://www.ecosystem.drgpcr.com/dr-gpcr-podcast/ep-168-with-dr.-maria-majellaro-from-celtarys #GPCRcommunity #DrGPCR #FluorescentLigands #GPCRdrugDiscovery #ScientificLeadership #BiotechInnovation | Dr. GPCR Ecosystem
A thesis project, a mentor’s advice, and a leap during the pandemic changed everything. A thesis project, a mentor’s advice, and a leap during the pandemic changed everything.
- 220 GPCRs. One platform. Endless questions. In Ep.167 of the Dr. GPCR Podcast, Tom Sakmar and Ilana Kotliar reveal a full GPCR-RAMP interaction map—powered by Luminex, dual-tagged constructs, and open science. Big win for the GPCR community. ✳️ Listen now: Ep 167 with Drs. Tom Sakmar & Ilana Kotliar #GPCRresearch #DrGPCR #GPCRpodcast #GPCRtools #OpenScience | Dr. GPCR Ecosystem
GPCR Podcast, Tom Sakmar and Ilana Kotliar reveal a full GPCR-RAMP interaction map—powered by Luminex, dual-tagged GPCR Podcast, Tom Sakmar and Ilana Kotliar reveal a full GPCR-RAMP interaction map—powered by Luminex, dual-tagged
- Ever wondered how we perceive bitterness? 👅🔬 Researchers have unveiled the cryo-EM structure of TAS2R14, the most promiscuous bitter taste receptor, bound to the drug flufenamic acid (FFA) and its signaling partner gustducin! 🌟 This discovery reveals an unusual dual binding mode of FFA and offers tools for site-targeted compound design. 🧪✨ Learn more about this exciting breakthrough in bitter taste signaling. | Dr. GPCR Ecosystem
🌟 This discovery reveals an unusual dual binding mode of FFA and offers tools for site-targeted compound 🌟 This discovery reveals an unusual dual binding mode of FFA and offers tools for site-targeted compound
- A casual postdoc in Santiago. A bold yes during the pandemic. Now? A biotech startup solving GPCR challenges worldwide 🌎 Celtarys Research didn’t follow the script, and neither does their chemistry. 🎧 In this week’s episode, Dr. Maria Majellaro talks about trusting your gut, learning to lead, and building science that scales. ✳️Celtarys is ready to support your assay development. Get to know more: Celtarys Research | Dr. GPCR Ecosystem | Dr. GPCR Ecosystem #GPCRtools #GPCRtrainingProgram #DrGPCR #BiotechLeadership | Dr. GPCR Ecosystem
A bold yes during the pandemic. Now? A bold yes during the pandemic. Now?
- Dr. Steven Foord | Dr. GPCR Ecosystem
He introduced molecular pharmacology to a wide range of the company's GPCR projects and was able to initiate
- Dr. Claudia Stäubert | Dr. GPCR Ecosystem
biochemistry from Leipzig University (Germany) being already fascinated by G protein-coupled receptors (GPCRs) due During my Ph.D. at the International Max Planck Research School “The Leipzig School of Human Origins” Quick recap Yamina and Claudia had a wide-ranging discussion about Claudia's work on metabolites and interest in attending a meeting about GPCRs and metabolism in the UK, but was unsure if she could make it due
- Dr. Elva Zhao | Dr. GPCR Ecosystem
run in the mountains, play with Tilly (a 9-year old retired greyhound), collecting mini shoes, and hang
- Session VI | Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem
Authors & Affiliations "Groff, Karenna; Donaldson, Hayley; Anderson, Sebastian; Pitti, Kiran; Wang, Shuai Perry-Hauser1,2, Arturo Torres Herraez1,2, Dan Lowes1,2, Ying Zhu1,2, Siham Boumhaouad1,3, Eugene V. I initially became interested in GPCR signal transduction during my graduate training in the Department
