Explore Martin Marro’s impact on GPCR drug discovery, assay innovation, and translational pharmacology bridging academia, pharma, and biotech. << Back to podcast list Strategic Partner(s) GPCR Assay Strategy The data eventually showed that super agonism in the cAMP assay predicted in vivo efficacy, and the molecule GPCR Learning Ecosystem ✔ Full Masterclass library ✔ Terry's Pharmacology Corner ✔ Advanced GPCR courses GPCR Podcast? Leave a Review.

Randy Hall on the receptor tail the field ignored, the adhesion GPCR experiment that did the opposite Skepticism first, then a crowded field The early data drew hard questions at Gordon conferences from Hall's counterpoint is that adhesion GPCRs are not only adhesive proteins, they are also GPCRs, with GPCR Learning Ecosystem ✔ Full Masterclass library ✔ Terry's Pharmacology Corner ✔ Advanced GPCR courses GPCR Podcast? Leave a Review.

“Allosteric modulation in GPCRs is so novel and so exciting. We produce great data, but we also joke around. That’s how we work best.” Translating Discovery into Therapy: Bench to Bedside Vision Ben’s work seeks to merge in vitro mechanistic data GPCR Learning Ecosystem ✔ Full Masterclass library ✔ Terry's Pharmacology Corner ✔ Advanced GPCR courses GPCR Podcast? Leave a Review.

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neuronal tissue - Automated, experimenter free behavioral assays as a response to human bias in the data specifically because a human presence, and even which human is present, measurably skews mosquito attraction data olfactometer assay - Moving to automated, video tracked behavioral assays to remove human bias from the data GPCR Learning Ecosystem ✔ Full Masterclass library ✔ Terry's Pharmacology Corner ✔ Advanced GPCR courses GPCR Podcast? Leave a Review.

My initial focus was on creating an automated chimeric homology modeling pipeline for GPCRs and since systems, structure data, G protein and arrestin coupling and more. GPCR Unlock the Full Dr. GPCR Learning Ecosystem ✔ Full Masterclass library ✔ Terry's Pharmacology Corner ✔ Advanced GPCR courses GPCR Podcast? Leave a Review.

My initial focus was on creating an automated chimeric homology modeling pipeline for GPCRs and since systems, structure data, G protein and arrestin coupling and more. GPCR Unlock the Full Dr. GPCR Learning Ecosystem ✔ Full Masterclass library ✔ Terry's Pharmacology Corner ✔ Advanced GPCR courses GPCR Podcast? Leave a Review.

GPCR Ecosystem. GPCR and Celtarys Research Join Forces to Expand Access to Innovative GPCR Tools Boston, MA and Santiago GPCR, the global knowledge hub for G protein-coupled receptor (GPCR) research and education, is proud GPCR. GPCR provides a unique platform to reach scientists at every stage of GPCR research,” said Wilson Gomes

platform — through the career of a scientist who helped engineer that shift. failure Orphan GPCRs and the missing pharmacology of ~100 unassigned receptors GPCRs in oncology, immunology GPCR Ecosystem Unlock the Full Dr. GPCR Learning Ecosystem ✔ Full Masterclass library ✔ Terry's Pharmacology Corner ✔ Advanced GPCR courses GPCR Podcast? Leave a Review.

Insel and Krishna Sriram went to the primary data and concluded the claim was not supported. off-label drug use during a pandemic 25:00 Genetic determinants of severity — ACE1 isoforms and population data GPCR Ecosystem Unlock the Full Dr. GPCR Learning Ecosystem ✔ Full Masterclass library ✔ Terry's Pharmacology Corner ✔ Advanced GPCR courses GPCR Podcast? Leave a Review.

At GeneMode he leads the engineering team and the platform's weekly release cycle. 07:01 What GeneMode actually does that Excel can't 10:15 Onboarding a ten-person lab onto one shared platform management tool where scientists can manage their reagents, samples, and projects on one intuitive platform The team is planning on building even more tools that will make Genemod the go-to platform for all research GPCR Ecosystem Jin Choe on LinkedIn Jin Choe on Dr. GPCR Ecosystem Unlock the Full Dr.

Adhesion GPCRs Were Not Considered Real GPCRs For decades, adhesion GPCRs were assigned to the GPCR superfamily Running it on instinct, he obtained reproducible data that became his first publication. Adhesion GPCRs Open a Pandora's Box Adhesion GPCRs appear across nearly every biological process — from GPCR Ecosystem Unlock the Full Dr. GPCR Podcast? Leave a Review.

to Arey's published data by calling it wrong, he called his graduate advisor. But the data held. GPCR Ecosystem Unlock the Full Dr. GPCR Learning Ecosystem ✔ Full Masterclass library ✔ Terry's Pharmacology Corner ✔ Advanced GPCR courses GPCR Podcast? Leave a Review.

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<< Back to podcast list Strategic Partner(s) Developing new tools to uncover GPCR signaling patterns My particular projects revolve around developing new tools to study GPCR activity in ways that were not This research has led to a first-author Cell article on the development of a new biosensor platform called GPCR Learning Ecosystem ✔ Full Masterclass library ✔ Terry's Pharmacology Corner ✔ Advanced GPCR courses GPCR Podcast? Leave a Review.

overdose, she reflects on staying in academia, building translational experiments, and using real-world data Her research combines cutting-edge GPCR signaling studies with real-time public health data from Michigan Street Data : Xylazine-laced fentanyl in Michigan has jumped 30–60% in recent years. GPCR Learning Ecosystem ✔ Full Masterclass library ✔ Terry's Pharmacology Corner ✔ Advanced GPCR courses GPCR Podcast? Leave a Review.

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Class C GPCRs are structural and mechanistic outliers within the GPCR superfamily. Her work has produced structural data at the extracellular domain level and, more recently, full-length GPCR Ecosystem Unlock the Full Dr. GPCR Learning Ecosystem ✔ Full Masterclass library ✔ Terry's Pharmacology Corner ✔ Advanced GPCR courses GPCR Podcast? Leave a Review.

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GPCR Podcast episode with Joe St. GPCR The episode dives into how Joe and Chuck began collaborating with the Dr. GPCR ecosystem. Accounting Highs & Scientific Parallels Yamina draws a parallel between reconciling complex financial data You build systems, track data, and interpret outcomes.” – Chuck DeWeese Final Reflections: Growing Together with the story behind the podcast’s creation—how a moment at a Starbucks in Target led her to launch a platform

GPCR is to accelerate GPCR drug discovery by sharing the latest research and technology advances in the GPCR podcast. Dr. GPCR About Dr. GPCR Unlock the Full Dr. GPCR Podcast? Leave a Review.

The Sunahara lab utilizes biochemical, biophysical and pharmacological methodologies to study GPCR-G We continue to utilize these data to better understand the basis for receptor-G protein specificity and GPCR Unlock the Full Dr. GPCR Learning Ecosystem ✔ Full Masterclass library ✔ Terry's Pharmacology Corner ✔ Advanced GPCR courses GPCR Podcast? Leave a Review.

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Raimond Heukers , developed a nanobody platform within the research group and used this platform to develop up his own research line focusing on translational applications of GPCR-targeting nanobodies. GPCR Ecosystem Unlock the Full Dr. GPCR Learning Ecosystem ✔ Full Masterclass library ✔ Terry's Pharmacology Corner ✔ Advanced GPCR courses GPCR Podcast? Leave a Review.

They also explored the possibility of developing an ecosystem for the GPCR University. in activating GPCRs, a process that they found fascinating. Yamina emphasized its vision for the platform to be a place where researchers can find content, ask questions GPCR Learning Ecosystem ✔ Full Masterclass library ✔ Terry's Pharmacology Corner ✔ Advanced GPCR courses GPCR Podcast? Leave a Review.

where the pharmacology extends well beyond what equilibrium binding data can show. readout that captures a downstream marker, a surrogate signal, or a population average can yield clean data Because you can get this data and you interpret it one way, but if you don't know the nuances, the very GPCR Ecosystem Unlock the Full Dr. GPCR Podcast? Leave a Review.

He is the inventor of OB-002 as well as the key technology underlying Orion’s discovery platform. Since then Oliver has worked at the University of Geneva, where his research on peptide engineering and GPCR GPCR Ecosystem Unlock the Full Dr. GPCR Learning Ecosystem ✔ Full Masterclass library ✔ Terry's Pharmacology Corner ✔ Advanced GPCR courses GPCR Podcast? Leave a Review.

Mike shared his strategy of developing preliminary projects and gathering data to strengthen his application GPCR Targeted Drugs and Gene Regulation in Cancer Cells Mike presented research on the effect of GPCR-targeted GPCRs and Cancer Immune Modulation Yamina and Mike had a discussion about their research on GPCRs, specifically GPCR Learning Ecosystem ✔ Full Masterclass library ✔ Terry's Pharmacology Corner ✔ Advanced GPCR courses GPCR Podcast? Leave a Review.

bias, shows how to detect and quantify it using reliable functional assays, and discusses how these data GPCR ecosystem, Terry hosts Terry's Corner, a live room where GPCR scientists get direct access to him It's where the mechanistic questions that usually sit beneath the data get asked out loud, and where GPCR Dr. GPCR is a membership-based nonprofit ecosystem dedicated to advancing GPCR-targeted drug discovery.