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light-harvesting antennas, capturing light from all directions, unlike the dipole-dipole alignment needed Quite often, there is a need to amplify the signal  strength to detect them, which can be achieved by

These complex properties have driven the need for development of specialized tools that can sense neuropeptide

Serafini described his connection to GPCRs as tangential but inevitable: "I feel like I never was particularly

To exert their functions requiring high sensibility and specificity, T cells need to integrate different

through expression systems, chemical modulation, or engineered desensitization—provides the clarity needed Direct input  on future topics, aligning content with your team’s real-world needs.

GPCRs use radioligands, whose limitations, especially safety concerns, low temporal resolution and the need Thus, rational design using efficient synthetic strategies is needed to make these probes as specific

layers of interconnected nodes which learn hierarchical representations of the data, eliminating the need field: 1) the quality and availability of data can be a challenge in AI-driven drug discovery; 2) the need Regulatory challenges, ethical considerations, and the need for interpretability of AI-driven models will need to be addressed to fully realize the potential of AI in GPCR drug discovery.

For chemoreception, the lysine is not needed.

As a result, there is an ongoing need to develop novel approaches to monitor and to modulate GPCR activation

However, many new targets, such as Mas-related GPCRs and unexpected new pathways need to be also explored

Read how scientific need and timing drove the leap from academia to application.  

neuropeptide activity for the treatment of corneal diseases with promising results, necessitating the need

Thus, we need to know much more about the structures of receptor-ligand complexes at high resolution.

of life during treatment coupled with brain tumour recurrence; thus, new treatments are desperately needed

Pancreatic ductal adenocarcinoma, β-blockers and antihistamines: A clinical trial is needed Jillian G and Immunology Pancreatic ductal adenocarcinoma, β-blockers and antihistamines: A clinical trial is needed

Join Now — Access Immediate, Actionable Insight   You’ll gain the insight needed to:   Interpret complex

in immune cells underscores their potential roles in modulating immune responses and highlights the need

However, a clear picture is needed to unravel TRPM3's full potential as experimental tool, diagnostic

Kenakin reveals  the substrate strategy needed for credible DDI assessment. Why Terry’s Corner Give You The GPCR Pharmacology Insights You Need Terry’s Corner gives discovery scientists

If you need a plasmid for your research or you want to share your materials, this is the place to go.

Hence, new β3 -AR agonists are needed as starting points for drug development.

variety, leading to insufficiently described structure-activity relationships, hence illustrating the need

However, the increasing rate of cannabis use among pregnant women has presented an urgent need to investigate

and non-specific interactions introduce noise at precisely the stage where medicinal chemistry teams need physiologically grounded triage of ligand candidates—exactly the type of early clarity medicinal chemistry teams need

Why Traditional Radioligand Methods Fall Short for Modern Screening Needs Radioligand binding assays provided as a complete CB2 HCS service—allowing teams to integrate fluorescent ligand technologies without needing

AlphaFold2 uses an AI-driven approach that eliminates the need for structural templates, allowing it

therapeutic options are limited, novel targets and agents for therapeutic intervention are urgently needed

diffusion to PK–PD dissociation, Kenakin equips you with the kinetic models and biological context needed

The GPCR field needs thinkers who can direct platforms, not just operate them.

For Early-Career Scientists: Your pivotal moment might not feel like fireworks.