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Results found for "Owen P. McGuinness"
- 📢 GPCR Update: August 19-25, 2024 | Thrilling Announcement: New Pharmacology Course Dates & Exclusive Discounts Inside!
Enrollment is now open to the public! Milestone in GPR68 Drug Discovery Project Ambrosia lands $16m to ‘improve on existing GLP-1 drugs’ Opening
- How to Design GPCR Drugs That Work in Vivo: Strategy, Tools, and Insights
Career opportunities: Senior Scientist, Phage Display | Manager, CMC Management | Translational R&D openings Weekly research, careers & event intelligence 🤝 Members-only networking, AMAs & matchmaking 💡 Support open
- Orthosteric vs Allosteric Interactions— and the pHSense Shift in Internalization
That subtle distinction opened the door to a brand-new assay format. context, you’ll see the signal early, cut delays, and make cleaner portfolio decisions while supporting open Weekly research, careers & event intelligence 🤝 Members-only networking, AMAs & matchmaking 💡 Support open
- Illuminating the draggable GPCR-ome
Bryan Roth There are 10 open tickets available. Get yours now!
- Signals in Motion: Pain, Metabolism & Terry’s Corner
24% weight loss, CagriSema delivered 22.7% in Phase 3, and semaglutide’s Canadian patent expiry is opening
- Understanding Enzyme Inhibition In GPCR Discovery Programs
Plus: top tracks to watch at GPCR Forum 2025, fresh postdoc openings at the ADME/signaling interface Weekly research, careers & event intelligence 🤝 Members-only networking, AMAs & matchmaking 💡 Support open
- 📰 GPCR Weekly News, June 3 to June 9, 2024
More details will be shared soon, and registration will open in July 2024. Dr. Candidate DT-7012 Crinetics Announces Positive Initial Findings at ENDO 2024 for Atumelnant in Two Ongoing, Open-Label
- Free-Energy Simulations Support a Lipophilic Binding Route for Melatonin Receptors
subtypes, as assessed by metadynamics simulations, and during ligand unbinding it frequently assumes an open Our simulations also suggest that the open state of Tyr5.38 generates a small pocket on the surface of
- From Venice to Virtual Molecules: Alessandro Nicoli’s Unexpected Journey into Computational Chemistry
“It was not just a molecule—it was a partner interacting with a protein or DNA… that opened a new world
- 📰 GPCR Buzz: August 5-11, 2024 | Top Highlights from DrGPCR University!
s Check out the details of each course below: Open to the Public: Enrollment is Now Available! Secure your spot before public enrollment opens!
- Reversible Photocontrol of Dopaminergic Transmission in Wild-Type Animals
Azodopa is the first photoswitchable dopamine agonist with demonstrated efficacy in wild-type animals and opens
- Viral G Protein-Coupled Receptors Encoded by β- and γ-Herpesviruses
and U51; Epstein-Barr virus with one: BILF1; and Kaposi's sarcoma-associated herpesvirus with one: open
- Integrative model of the FSH receptor reveals the structural role of the flexible hinge region
How this HR is involved in hormone binding and signal transduction is still an open question.
- PLC-IP3-ORAI pathway participates in the activation of the MRGPRB2 receptor in mouse peritoneal...
However, the opening of ion channels mediated by MRGPRB2 activation remains unclear.
- G protein coupling and activation of the metabotropic GABAB heterodimer
further leads to the TMD rearrangement and deeper insertion of the α5 helix that causes the Gα subunit to open
- How Collaboration Sparked a GPCR Imaging Breakthrough in Chemical Biology
That breakthrough launched the first wave of GLP-1R visualization studies and opened the door to deeper JB emphasizes how much of their progress came from staying open, asking questions freely, and engaging
- Profiling Immune Cell and Platelet Transcriptomes
The ability to profile GPCR expression in a highly sensitive manner also opens doors for exploring the
- 📰 GPCR Weekly News, May 27 to June 2, 2024
More details will be shared soon, and registration will open in July 2024. Dr. Conference Crinetics Announces Positive Initial Findings At Endo 2024 For Atumelnant In Two Ongoing, Open-Label
- APEX2/AUR Biosensor: A Powerful Tool for Protein Interaction and Trafficking
The development of molecular tools to study GPCR trafficking in real-time opens new avenues for understanding
- Maria’s Travel Blogs: ACSMEDI-EFMC Medicinal Chemistry Frontiers 2025
Ingo Hartung’s opening.
- Structure-Based Discovery of Negative Allosteric Modulators of the Metabotropic Glutamate Receptor 5
of class C G protein-coupled receptors (GPCRs) revealed the location of allosteric binding sites and opened
- 📰 GPCR Weekly News, January 15 to 21, 2024
Due to popular demand, we have opened additional spots. If you'd like to join colleagues and Dr. The course covers basic pharmacology in four weekly segments and is open to all with a free site membership
- Structure-Based Discovery of Negative Allosteric Modulators of the Metabotropic Glutamate Receptor 5
of class C G protein-coupled receptors (GPCRs) revealed the location of allosteric binding sites and opened
- 📰 GPCR Weekly News, December 11 to 17, 2023
Registrations are open to Dr. GPCR Ecosystem Premium Members and free site Members! Update Including Clinically Meaningful Proof-of-Concept Data From Phase 2a Clinical Study Neurocrine opening
- How a Failed Experiment Created a Powerful GPCR Imaging Tool
It opened a new category of problems to solve more efficiently.
- Increased Anxiety-like Behaviors in Adgra1-/- Male But Not Female Mice are Attributable to...
We found that Adgra1-/- male but not female mice exhibited elevated anxiety levels in the open field,
- 📰 GPCR Weekly News, May 6 to 12, 2024
Stay tuned as we plan to open registrations for both classes in July 2024. Dr. Abstract submissions and registrations will open soon.
- From Pipettes to Platforms: The Evolution of GPCR Research
Technical mastery opened doors, but what kept her moving was knowing when to say yes before everything
- Enhancing GPCR Research Outreach | Dr GPCR University early-bird registration ends soon!
GPCR University Early-Bird Registration Open for Premium Members!
- 📰 GPCR Weekly News, June 10 to 16, 2024
Stay tuned for more details, and mark your calendars for registration opening in July 2024. Dr.













