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scaffolding protein β-arrestin2 are key integrated signaling nodes in various biological processes, and both

CB1 receptor mRNA and protein has been recognized within myotubes and tissues of skeletal muscle from both This can be deduced from the qRT-PCR assays; triggering CB1 receptors amplifies both NR4A1 and NR4A3

Although such pheromone/receptor systems are likely to function in both mate choice and prezygotic isolation with the respective domains in SoMam2 and SoMap3, which revealed differences between the receptors both

migration was detected by the Boyden chamber migration assay, performed on macrophages derived from both

It’s not often when you get the best of both worlds - nano-bodies and #GPCRs.

These tools enable high-resolution binding studies, kinetic analysis, and live-cell imaging, empowering both

Crinetics recently reported that administration of CRN04894 reduced both serum cortisol levels and 24

Methods of identifying and determining the levels of different chemerin forms in both mass and activity

commercial leader with more than three decades of experience leading sales and marketing operations for both

with functional data, the structures reveal the key factors that govern the recognition of CX3CL1 by both

signals in PFC astrocytes are time locked to dopamine release and are mediated by α1-adrenergic receptors both

appreciated how fast the ligand diffuses and is distributed homogeneously within monolayers, staining both The dashed line represents the frontier between both cell types.

Both CGRP populations and their amygdala projections are required for multi-sensory threat perception

Because even the best data means nothing without structure. That’s the Lego Bucket Problem.   

, in the case of promiscuous receptors they found that these receptors shared conserved residues of both G protein families, suggesting that receptors that activate both Gs and Gi/o do so by combining the

importance of functional selectivity/biased signaling has led to the discovery of biased compounds as both

Protein-Coupled Receptors (GPCRs), today announced that it will be presenting important new data at both

Microiontophoretically applied H1152, a ROCK inhibitor, and siRNA-induced ROCK2 knockdown both depressed Finally, two neurotransmitters, TRH, and 5-HT, which are both known to increase MN IME by TASK1 inhibition

We are closely monitoring any regulation changes from both Boston and Massachusetts with regard to in-person

The cornea is the most densely innervated tissue of the body and possesses both immune and vascular privilege

Recently, X-ray structures of both AngII receptors (AT1 and AT2 receptors) bound to peptide and non-peptide

In contrast to A2AAR agonists, which simultaneously interact with both Ser2777.42 and His2787.43, 2 only

Def and Mrgpra2 mutant animals both exhibited skin dysbiosis, with reduced microbial diversity and expansion

Both groups of metabolites suppress anti-inflammatory interleukin-10 signaling in human macrophage cell

Additionally, RAMP2 increases both PTH- and PTHrP-triggered β-arrestin2 recruitment to PTH1R.

use of various drugs including orthosteric and allosteric ligands acting on either mGluR2, mGluR3 or both

She will maintain both of these roles, in addition to her role at Exscientia.

In this review, we discuss both the ‘friend’ and ‘foe’ features of TGR5 by summarizing its tumor-suppressing

a NanoBRET-based conformational histamine H3 receptor (H3R) biosensor that allowed the detection of both