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- "Solving financial puzzles feels just like solving scientific ones," says Joe St. Germain from Company Launch Partners. Behind every successful research organization, there is a rock-solid operations team. Don’t miss this rare conversation bridging science, structure, and strategy with Chuck DeWeese & Joe St. Germain. ✳️ Tune in now: Ep 165 with Chuck DeWeese & Joe St. Germain #gpcr #DrGPCR #ScienceStartup | Dr. GPCR Ecosystem
Germain #gpcr #DrGPCR #ScienceStartup Published on May 1, 2025 Category Dr. Germain #gpcr #DrGPCR #ScienceStartup Previous Next Recent Articles Why Biotech Fundraising Fails Due
- A high-resolution deep mutational scan of MC4R reveals how thousands of genetic variants impact obesity-linked signaling pathways and highlights new opportunities for precision drug discovery Subscribe to the Dr. GPCR Newsletter 📰 and get the latest GPCR News delivered to your inbox ➡️ https://www.ecosystem.drgpcr.com/receptor-activation-and-signaling/high-resolution-deep-mutational-scanning-of-the-melanocortin-4-receptor-enables-target-characterization-for-drug-discovery #gpcr#drgpcr | Dr. GPCR Ecosystem
high-resolution-deep-mutational-scanning-of-the-melanocortin-4-receptor-enables-target-characterization-for-drug-discovery #gpcr#drgpcr high-resolution-deep-mutational-scanning-of-the-melanocortin-4-receptor-enables-target-characterization-for-drug-discovery #gpcr#drgpcr
- Did you know allosteric modulators can change the GPCR G protein subtype selectivity? Have a look at this study to dive deep into its molecular mechanism. Subscribe to the Dr. GPCR Newsletter 📰 and get the latest GPCR News delivered to your inbox. | Dr. GPCR Ecosystem
gpcr-binders-drugs-and-more/design-of-allosteric-modulators-that-change-gpcr-g-protein-subtype-selectivity #gpcr #drgpcr
- New Episode Alert! 🎙️ Ep. 163 of the Dr. GPCR Podcast is here! 🚀 This time, we sit down with Dr. Dmitry Veprintsev to discuss the importance of asking the right GPCR questions. Whether you're a researcher, student, or GPCR enthusiast, this episode is packed with insights that will challenge how you think about your experiments. ✳️Tune in at https://www.ecosystem.drgpcr.com/dr-gpcr-podcast/ep-163-with-dr.-dmitry- #DrGPCR #GPCRPodcast #Pharmacology #DrugDiscovery #Biotech #GPCRs | Dr. GPCR Ecosystem
-dmitry- #DrGPCR #GPCRPodcast #Pharmacology #DrugDiscovery #Biotech #GPCRs Published on April 1, 2025 -dmitry- #DrGPCR #GPCRPodcast #Pharmacology #DrugDiscovery #Biotech #GPCRs Previous Next Recent Articles
- encoding and decoding selectivity and promiscuity in the human chemokine GPCR interaction network | Dr. GPCR Ecosystem
. ➡️ Read the paper: https://www.cell.com/cell/fulltext/S0092-8674(25)00398-8 #DrGPCR #GPCR #Chemokines
- ⚠️ Registration Deadline today! This is your last chance to register for Principles of Pharmacology II - Advanced Methods for the Optimization of Candidate Selection with Dr. Terry Kenakin. Learn more about new ligands and new GPCR behaviors that produce unique drug profiles. | Dr. GPCR Ecosystem
https://www.ecosystem.drgpcr.com/advanced-methods-for-the-optimization-of-candidate-selection #gpcr #drgpcr
- insights into g protein coupling preference from cryo em structures of gq bound PTH1R | Dr. GPCR Ecosystem
utm_content=buffer3b1fa&utm_medium=social&utm_source=twitter.com&utm_campaign=buffer #DrGPCR #GPCR #PTH1R
- master gpcr pharmacologic models before its too late | Dr. GPCR Ecosystem
utm_source=twitter.com&utm_campaign=buffer #GPCR #Pharmacology #DrugDiscovery #ScientificLeadership #DrGPCR
- New biosensor technologies are shedding light on GPCR dynamics directly in cells, offering exciting possibilities for multiplexing and miniaturization! Curious about how these advances could impact drug discovery? Check out the latest review on GPCR biosensors. Check out the latest GPCR news in the Ecosystem today! You’ll need to register but don’t worry, it’s Free! | Dr. GPCR Ecosystem
Check out the latest GPCR news in the Ecosystem today! Check out the latest GPCR news in the Ecosystem today! www.ecosystem.drgpcr.com/reviews/gpcr-biosensors-to-study-conformational-dynamics-and-signaling-in-drug-discovery #GPCR #DrGPCR
- GPCRs regulate key biological processes, but how exactly do inhibitory Gαi proteins control signal transduction beyond adenylyl cyclase suppression? New research sheds light on these pathways! ✨ Want to learn more? Did you know that we work hard to bring you the most recent GPCR News, weekly? Catch up today in the Ecosystem using your free site membership! | Dr. GPCR Ecosystem
Catch up today in the Ecosystem using your free site membership! Catch up today in the Ecosystem using your free site membership! receptor-activation-and-signaling/germline-mutations-in-a-g-protein-identify-signaling-cross-talk-in-t-cells #GPCR #DrGPCR
- Did you know? 🌟 Researchers have developed reversibly photoswitchable allosteric modulators for Class A GPCRs! 🧬💡 These innovative compounds, “Photo-BQCisA” and “Photo-BQCtrAns,” offer subtype-selective precision by combining allosteric modulation with light control, paving the way for new therapeutic strategies targeting muscarinic receptors (M1-M5). 🔬✨ Learn more about this breakthrough in the Ecosystem! | Dr. GPCR Ecosystem
. 🔬✨ Learn more about this breakthrough in the Ecosystem! therapeutic strategies targeting muscarinic receptors (M1-M5). 🔬✨ Learn more about this breakthrough in the Ecosystem ➡️ buff.ly/4fgX4ZH #gpcr #drgpcr Previous Next Recent Articles Why Biotech Fundraising Fails Due to Intellectual
- pharmacology at your fingertips terrys corner launches | Dr. GPCR Ecosystem
https://www.ecosystem.drgpcr.com/post/pharmacology-at-your-fingertips-terry-s-corner-launches #DrGPCR
- How sensitive can a GPCR really be | Dr. GPCR Ecosystem
GPCR Premium → https://www.ecosystem.drgpcr.com/gpcr-university #GPCR #DrGPCR #pharmacology #drugdiscovery
- Weekly News October 23 | Dr. GPCR Ecosystem
#DrGPCR #GPCR Previous Next Recent Articles
- From Pipettes to Platforms The Evolution of GPCR Research | Dr. GPCR Ecosystem
Premium for deeper tools and insights: https://www.ecosystem.drgpcr.com/gpcr-university-pricing #GPCR #DrGPCR
- How do GRK-specific phosphorylation barcodes influence β-arrestin binding to GPCRs? New cryo-EM structures from Chen et al. (Nature, 2025) reveal that β-arrestin1 and β-arrestin2 form distinct complexes with ACKR3 depending on whether it's phosphorylated by GRK2 or GRK5, shaping arrestin conformation, complex stability, and engagement mode. Surprisingly, arrestin’s finger loop didn’t dive into the receptor core. Instead, it latched onto the micelle surface, breaking canonical expectations. Also, β-arrestin2 lacks a membrane anchor, making it more dynamic — a potential clue to its functional specialization. These findings underscore how barcode location + arrestin isoform = unique signaling outcomes. open book Read the full study: Inside Out: Mapping GPCRs from Membrane Codes to Market Moves #GPCRs #Arrestin #ACKR3 #GRKs #CryoEM #StructuralBiology #SignalingBias #Phosphorylation #DrGPCR | Dr. GPCR Ecosystem
Market Moves #GPCRs #Arrestin #ACKR3 #GRKs #CryoEM #StructuralBiology #SignalingBias #Phosphorylation #DrGPCR Market Moves #GPCRs #Arrestin #ACKR3 #GRKs #CryoEM #StructuralBiology #SignalingBias #Phosphorylation #DrGPCR
- Dr. GPCR University Vault | Dr. GPCR Ecosystem
An exclusive, members-only archive of expert talks from past DrGPCR events, plus comprehensive courses New sessions are uploaded after each DrGPCR Summit or Symposia, plus we regularly add new courses, news
- ama session sept 18 post 3 | Dr. GPCR Ecosystem
://www.ecosystem.drgpcr.com/terry-corner ✳️ Next AMA Session: ⚠️ Today, Oct 30 | 12–1 PM EST #GPCR #DrGPCR
- ama session sept 18 post 2 | Dr. GPCR Ecosystem
accelerating-gpcr-drug-discovery-what-40-years-of-pharmacology-reveal ✳️ Next AMA Session: October 30 | 12–1 PM EST #GPCR #DrGPCR
- ep 175 with jens carlsson clip 2 | Dr. GPCR Ecosystem
GPCR Podcast: model predict discover #DrGPCR #GPCR #CollaborationInScience #ComputationalChemistry #Pharmacology
- ep 175 with jens carlsson clip 3 | Dr. GPCR Ecosystem
. 👉 Watch the full episode: model predict discover #GPCR #DrGPCR Previous Next Recent Articles
- How GPCR Collaboration Built an Innovation Engine | Dr. GPCR Ecosystem
GPCR collaboration at Monash shows how shared lab ecosystems can reshape innovation and accelerate drug An ecosystem where GPCR innovation accelerated — not because of a single star scientist, but because GPCR Premium #GPCR #DrGPCR #DrugDiscovery #Innovation #ScienceLeadership #Collaboration Previous Next
- Scientific careers are not just built on brilliance | Dr. GPCR Ecosystem
brilliance Scientific careers aren’t just built on brilliance Published on November 14, 2025 Category Dr.GPCR episode: https://www.ecosystem.drgpcr.com/dr-gpcr-podcast/leadership-luck-and-gpcr-signaling #GPCR #DrGPCR
- irreversible drugs post 2 | Dr. GPCR Ecosystem
www.ecosystem.drgpcr.com/post/beyond-clearance-the-strategic-power-of-irreversible-drug-binding #GPCR #DrGPCR
- University | Dr. GPCR Ecosystem
DrGPCR helps you understand and apply that knowledge — through structured training, expert context, and At Dr.GPCR University, you’ll find: Courses: Dive deep into curated educational content designed by experts To register for any course, you must have a FREE Ecosystem member account . We will contact each person individually to help them set up a FREE Ecosystem Membership .
- ep 175 with jens carlsson release picture | Dr. GPCR Ecosystem
GPCR Podcast : https://www.ecosystem.drgpcr.com/dr-gpcr-podcast/model-predict-discover #DrGPCR #GPCR
- University Pricing | Dr. GPCR Ecosystem
DrGPCR helps you understand and apply that knowledge — through structured training, expert context, and Join thousands of researchers who trust DrGPCR for cutting-edge insights and resources.
- irreversible drugs post 1 | Dr. GPCR Ecosystem
GPCR Ecosystem #GPCR #DrGPCR #Pharmacology #DrugDiscovery #MedicinalChemistry #PKPD #ReceptorKinetics
- irreversible drugs post 3 | Dr. GPCR Ecosystem
GPCR Ecosystem #GPCR #DrGPCR #Pharmacology #DrugDiscovery #Kinetics #ReceptorPharmacology #MedicinalChemistry
- ama session sept 18 post 1 | Dr. GPCR Ecosystem
GPCR Ecosystem ✳️ BONUS — Live AMA Session: Get direct, unfiltered access to Terry. #GPCR #DrGPCR #Pharmacology #DrugDiscovery #Biotech #AllostericModulation #Kinetics #AssayDevelopment
