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Results found for "GPCR research community"

  • Cholesterol-Dependent Dynamics of the Serotonin1A Receptor Utilizing Single Particle Tracking: ...

    Receptor Utilizing Single Particle Tracking: Analysis of Diffusion Modes "G protein-coupled receptors (GPCRs Serotonin1A receptors are important members of the GPCR family and are implicated in neuropsychiatric To explore the role of cholesterol in lateral dynamics of GPCRs, we utilized single particle tracking results bring out the interdependence of cholesterol and actin cytoskeleton in regulating diffusion of GPCRs Read more at the source #DrGPCR #GPCR #IndustryNews

  • Integrating Fluorescent Ligands into Flow Cytometry: Enhancing GPCR Analysis Beyond Traditional Antibody Staining

    In order to expand its role in GPCRs, which antibodies tend to have more trouble binding to. How Fluorescent Ligands Transform Flow Cytometry in GPCR Analysis GPCRs are a tough target in traditional conjunction with fluorescent tags to study biased signaling pathways, improving our understanding of GPCR Illuminating the life of GPCRs. Cell Commun Signal. 2009 Jul 14;7:16. doi: 10.1186/1478-811X-7-16  Siddiqui S, Livák F.

  • GPCR Drug Discovery at Discovery on Target: Why This Track Is About More Than Receptors

    GPCR , our mission is simple: connect the GPCR community, share knowledge, and accelerate innovation Over the years, we’ve built a global network of researchers, biotech leaders, and pharma innovators who GPCR  community, you already know about Terry’s Corner  — our exclusive, on-demand pharmacology series research . the globe meet Boston’s vibrant life sciences hub. ✨ Spark collaborations. ✨ Strengthen the GPCR community

  • Subscribe to Dr. GPCR Newsletter Today!

    Did you know that each month we collect the most recent #GPCR publications and the newest Biotech/Pharma GPCR-related news? GPCR monthly newsletter for FREE! ➡️ https://bit.ly/3cCI4em #gpcr #drgpcr

  • Time is your enemy, GPCRs are your friend

    Stuart Maudsley on how an aging physiological context affects #GPCR signaling #drgpcr. Register here (FREE) https://www.ecosystem.drgpcr.com/dr-gpcr-virtual-cafe/ #gpcr #drgpcr #virtualcafe

  • Dr. Juan José Fung - Dr. GPCR Podcast

    GPCR Podcast is back this week with a brand new episode. Our guest is none other than Dr. Juan Jose Fung, Principal Scientist, at GPCR Therapeutics. https://buff.ly/32fzGbO #gpcr #drgpcr #podcast

  • Dr. Ben Myers - Dr. GPCR Podcast

    GPCR podcast is now available! Our guest is Dr. Ben Myers! studying sensory #ionchannels to the group leader at the University of Utah investigating Class F #GPCRs Listen nowhere you get your podcasts https://www.ecosystem.drgpcr.com/dr-gpcr-podcast/ #gpcr #drgpcr

  • Bell-Evans model and steered molecular dynamics in uncovering the dissociation kinetics of ligands..

    kinetics of ligands targeting G-protein-coupled receptors "Recently, academic and industrial scientific communities ZMA241385 and agonist NECA that target the A2A adenosine receptor of the G-protein-coupled receptor (GPCR Read more at the source #DrGPCR #GPCR #IndustryNews

  • Learn about Dr. GPCR Ecosystem!

    GPCR is much more than a podcast? Come check out the brand new Dr. GPCR Ecosystem and explore its benefits! We have #GPCR News, Learning Center, Events, and more to discover! Learn More HERE ➡️ https://www.ecosystem.drgpcr.com/learning-center #gpcr #drgpcr

  • Production of human A2AAR in lipid nanodiscs for 19F-NMR and single-molecule fluorescence...

    describe production of the human A2A adenosine receptor (A2AAR), a class A G protein-coupled receptor (GPCR Read more at the source #DrGPCR #GPCR #IndustryNews

  • Dr. Tim De Groof - Dr. GPCR Podcast

    GPCR podcast is now available! Our guest is Dr. Tim De Groof! It’s not often when you get the best of both worlds - nano-bodies and #GPCRs. Listen where you get your podcasts https://www.ecosystem.drgpcr.com/dr-gpcr-podcast #gpcr #drgpcr #podcast

  • Dr. JoAnn Trejo - Dr. GPCR Podcast

    GPCR podcast is now available! Our guest is Dr. JoAnn Trejo! Listen where you get your podcasts https://www.ecosystem.drgpcr.com/dr-gpcr-podcast #gpcr #drgpcr #podcast

  • Ode to GPCRs

    year, with the month of October, comes the excitement of the Nobel session to the global scientific community also acknowledges the relative importance of a particular scientific area received from the scientific community Therefore, the presentation of 10 or more Nobel prizes highlights the importance of research work on and Ulf Svante von Euler for their work on the release and reuptake of neurotransmitters in neural communication more accolades from the global scientific community and continue to make large scientific discoveries

  • Dr. Nicola J. Smith - Dr. GPCR Podcast

    GPCR Podcast, we have Dr. https://www.ecosystem.drgpcr.com/dr-gpcr-podcast/ #gpcr #drgpcr #podcast

  • Differential binding of Δ9-tetrahydrocannabinol derivatives to type 1 cannabinoid receptors (CB1)

    Introduction Cannabinoid receptors are GPCRs, and two main types exist, CB1R and CB2R. for CB1R in live cells and the PHERAstar FSX is the ideal microplate reader for characterizing the GPCR-ligand occurring Δ9-tetrahydrocannabinolderivatives to cannabinoid CB1 and CB2 receptors, Pharmacological Research

  • Unconventional GPCR-PKA Communication in the Hedgehog Pathway

    GPCR Virtual Cafe is back! Our first guest speaker is none other than Dr. Ben Myers! Learn about communication between GPCRs and PKA, Class F GPCR Smoothened & the Hedgehog signaling pathway https://www.ecosystem.drgpcr.com/dr-gpcr-virtual-cafe

  • Structural basis of GPCR coupling to distinct signal transducers: implications for biased signaling

    August 2022 "Three classes of G-protein-coupled receptor (GPCR) partners - G proteins, GPCR kinases, and arrestins - preferentially bind active GPCRs. Our analysis suggests that the structures of GPCRs bound to these interaction partners available today In view of this, three possibilities are conceivable: (i) there are no generalizable GPCR conformations Read more at the source #DrGPCR #GPCR #IndustryNews

  • Structural basis of adhesion GPCR GPR110 activation by stalk peptide and G-proteins coupling

    However, the detailed mechanism of aGPCR activation remains elusive. The structures also unveil the rarely explored GPCR/G12 and GPCR/G13 engagements. Taken together, our study fills the missing information of GPCR/G-protein engagement and provides a framework for understanding aGPCR activation and GPR110 signaling." Read more at the source #DrGPCR #GPCR #IndustryNews

  • GPCR Agonist-to-Antagonist Conversion: Enabling the Design of Nucleoside Functional Switches for...

    October 2022 GPCR Agonist-to-Antagonist Conversion: Enabling the Design of Nucleoside Functional Switches Herein, we demonstrate that a thiophene modification at the C8 position in the common adenine scaffold Read more at the source #DrGPCR #GPCR #IndustryNews

  • Dr. GPCR Virtual Cafe - Postponed

    GPCR Virtual Cafe with Matthew Eddy scheduled for tomorrow (Sep 29th, 2022) due to Hurricane Ian that #gpcr #drgpcr

  • Dr. Thomas P. Sakmar - Dr. GPCR Podcast

    GPCR podcast! Give it a listen to hear from Dr. Thomas P. Sakmar on how the molecular studies of rhodopsin paved the way to understanding #GPCRs Be sure to subscribe https://www.ecosystem.drgpcr.com/dr-gpcr-podcast/ #drgpcr #gpcr #podcast

  • Lysosomal GPCR-like protein LYCHOS signals cholesterol sufficiency to mTORC1

    Read more at the source #DrGPCR #GPCR #IndustryNews

  • Early Safety Assays: Identifying Showstoppers in GPCR Drug Discovery Pipelines Early

    As GPCR science and pharmacological innovation accelerate, timely guidance from foundational to advanced

  • Dr. Peter Robert Banks - Dr. GPCR Podcast

    GPCR podcast is now available! Our guest is Dr. Listen where you get your podcasts. https://www.ecosystem.drgpcr.com/dr-gpcr-podcast/ #gpcr #drgpcr #

  • From DNA day to GPCR genomics

    This intersection of genomics and GPCR research sparked a new era of a comprehensive understanding of Also, ongoing research may discover new GPCRs or refine existing data, which could lead to adjustments Another significant impact of genomics on GPCR research is the elucidation of receptor structure and References National Human Genome Research Institute, U. S. (2002) National Human Genome Research Institute.

  • Dr. GPCR Summit 2022 is coming!

    GPCR Summit 2022 held between October 10th and 16th. Dr. GPCR Summit is FREE for all Ecosystem site members! Become a member today, it's also free! ➡️ https://bit.ly/3wKZmfR #gpcr #drgpcr

  • Automated micro-plate-based methods for quantifying GPCR activation

    Joe Clayton from BioTek Instruments talk about automated micro-plate-based methods for quantifying #GPCR activation. https://www.ecosystem.drgpcr.com/dr-gpcr-virtual-cafe/ #drgpcr #gpcr #virtualcafe

  • A cryptic mode of GPCR regulation revealed

    October 2022 "Over three decades of research have provided thorough insights into G protein-coupled receptor (GPCR) regulation. Read more at the source #DrGPCR #GPCR #IndustryNews

  • Dr. GPCR Summit 2022 is coming!

    GPCR Summit is between October 10th to the 16th! ➡️ https://www.ecosystem.drgpcr.com/dr-gpcr-summit-2022 #gpcr #drgpcr

  • New Podcast, Sweet Structures & $2.2B GPCR Moves

    Hello Sweet GPCR Enthusiasts, This week at Dr. GPCR: a new podcast episode with Dr. GPCR Store is live!   — A tale of detergent tails: GPCR activation beyond ligands .   Explore this week’s research, tools, and biotech insights in one place. GPCR Team

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