Last summer, Julia worked at as the first-ever summer intern at Septerna, the GPCR-based biotechnology

Her work spans GPCR structural biology, membrane protein stabilization, allosteric modulation, and the Marshall in the room — a new category of GPCR biology opened, with heterodimers as obligate signaling Years of assumed peptide biology dissolved into a simpler truth hidden in the solvent. Oncology Ignored GPCRs for Decades — and Is Paying Attention Now Twenty years ago, cancer biologists Richard Henderson at the Laboratory of Molecular Biology in Cambridge, UK.

From Cell Assays to In Vivo Systems Fluorescent tools for imaging endogenous incretin receptors across biological systems Interrogating Incretin Receptor Biology Across Biological Complexity GLP-1 and GIP receptors , yet their precise localization, nanodomain organization, and functional engagement within complex biological fluorescent probes developed specifically for working with endogenous GLP-1R and GIPR across a range of biological intelligence, expert-led masterclasses, and structured engagement opportunities for scientists and biotech

Listeners will gain perspective on how asking broader questions about receptor biology can reshape drug His research spans four decades of GPCR signaling, from cyclic AMP and adrenergic receptor biology to His lab combines bioinformatic analysis of GPCR expression across human cancers with wet-lab validation intersects with cancer, immunology, and systems biology. Paul Insel was at the FASEB experimental biology meeting in Atlantic City.

Bioinformatics projects flourished. His research spans GPCR signaling in cancer biology, head and neck squamous cell carcinoma, and the molecular The bioinformatics arm called it "heaven."

Bender uses virtual docking to find chemical probes for orphan GPCRs - receptors biology can't study GUEST Bender is a postdoctoral fellow at UCSF working at the intersection of computational structural biology He trained as a structural biologist at Vanderbilt University, working with X-ray crystallography, protein Bender's work targets this gap directly - arguing that de-orphanizing a receptor biochemically and making They may vary slightly from the final edited version. 00:00 Introduction 01:31 From structural biology

This webinar explains the biological basis of signaling bias, shows how to detect and quantify it using The Biology Behind Bias Ligands produce differential pathway engagement at a single receptor because testing, and backed by thousands of peer-reviewed publications and partnerships with leading pharma and biotech intelligence, expert-led masterclasses, and structured engagement opportunities for scientists and biotech Expert-led webinars and masterclasses with leading researchers Structured networking for scientists and biotech

Ross Cheloha approaches these questions from a chemical biology perspective - using synthetic peptide His research combines peptide chemistry, chemical biology, and nanobody engineering to build mechanistic on the parathyroid hormone receptor and its downstream consequences for calcium homeostasis and bone biology The biology may have been using this distinction all along: two natural ligands for the same receptor Ross Cheloha is an Investigator at the National Institutes of Health in the Laboratory of Bioorganic

Gabriele Kockelkoren About Gabriele Kockelkoren I have a strong background in both physics and molecular biology

is currently the Senior Investigator and Chief of the Molecular Recognition Section, Laboratory of Bioorganic

Silvia Sposini " I'm originally from Rome, Italy, where I studied Biological Sciences as a BSc student

Ben Holland About Murat Tunaboylu "Murat Tunaboylu, Antiverse's CEO, has a software engineering and bioinformatics After switching to biotech, Murat has built cell imaging software and lab robots to accelerate cancer He has co-founded consultancy and biotech companies Svarlight and Antiverse. Murat Tunaboylu on the web Antiverse DSV Future of Drug Discovery Podcast Twist Bioscience LinkedIn Twitter

Arun Shukla leads a structural pharmacology lab in the Department of Biological Sciences and Bioengineering He completed his PhD at the Max Planck Institute of Biophysics in Frankfurt and postdoctoral training Episode Timeline 00:00 Introduction 02:15 From DNA quadruplexes to GPCR structural biology 06:32 The Sciences and Bioengineering. a biochemistry class where he learned about cell signaling that he became curious and wanted to learn

Neuroscience, and Artificial Intelligence and Human Health, as well as the Dean of The Graduate School of Biomedical To this end, her lab uses several computational structural biology tools and rational drug design approaches , ranging from molecular modeling, bioinformatics, cheminformatics, molecular dynamics simulations, free-energy in Computational Chemistry at the Second University of Naples and a postdoctorate in Computational Biophysics

Pain became more than biology — it became a personal strategy. At one point, he had a job offer at Roivant (a biotech firm known for repurposing shelved compounds), approach, though less common, could help pain research finally catch up with the complexity of real-world biology

non-psychedelic psychedelic for depression — and why the real bottleneck in GPCR drug discovery is the biology He earned his MD and biochemistry PhD at St. Louis University and trained in pharmacology at NIH and in molecular biology and psychiatry at Stanford It reframes the field's task from finding good targets to understanding the biology well enough to connect After receiving his MD and Ph.D. in Biochemistry from St.

We have developed an array of fluorescent biosensors to map kinase activity in living cells and are exploring

endothelial cells, cardiovascular target validation, thrombosis pharmacology, and metabolic disease biology drug discovery is grounded in classical physiology and driven by a willingness to enter fields - bone biology His belief in the biology has not changed. professional cost that nobody warns you about Moving between neuroscience, reproductive endocrinology, bone biology contributed to the discovery or development of 5 marketed drugs through his work spanning molecular, biochemical

Biotech founder Ajay Yekkirala shares how AI, GPCRs, and bold questions are driving next-gen pain therapeutics Ajay Yekkirala is a GPCR pharmacologist, biotech entrepreneur, and co-founder of Superluminal Medicines AI is reshaping how we understand protein dynamics , but only when driven by deep biological questions GPCR scientists interested in translational innovation Biotech investors and strategic leaders seeking Ajay’s work sits at the intersection of GPCR biology, AI, and translational medicine.

2021 Clarivate Analytics Highly Cited Researcher in two disciplines: Pharmacology & Toxicology and Biology & Biochemistry, a corresponding member of the International Union of Basic and Clinical Pharmacology Sexton is also a co-founder of the San Francisco-based biotechnology company Septerna Inc . Dr.

This research has led to a first-author Cell article on the development of a new biosensor platform called ONE-GO biosensors.

David Sykes " David Andrew Sykes, BSc Hons Pharmacology, MSc Molecular Biology and Biochemistry, PhD

Biotech Decision Vault by Attila Foris Strategic Business & Operating Systems Advisor Dr.

trafficking and recycling, and more recently the cannabinoid entourage hypothesis — combining BRET-based biosensors receptor tone Quantitative pharmacology as rescue operation — using operational models and BRET-based biosensors mechanistic story that guided a decade of biased-ligand drug discovery needs rebuilding from the underlying biology

GPCR was created to break down barriers across academia, biotech, pharma, and CROs—so knowledge, tools field , including: Academic researchers (PI, postdoc, student) Industry scientists and R&D leaders Biotech

He leads a multidisciplinary research team comprising biologists, chemists, physicists, engineers and journals such as Nature, Cell, New England Journal of Medicine, Journal of Clinical Investigation, PLoS Biology

want to support academic labs with the same high-quality tools, courses, and insights used by leading biotech

Pharma in Denmark; Full professor, department chair and director of the institute for pharmaceutical Biology

Berchiche obtained her Master’s and Ph.D. in Biochemistry at the University of Montreal in Canada before focusing on Systems Biology & AI to accelerate the quest for novel & safer drugs on GPCRs. and bioinformatics fields. In 1994, they became a Bioinformatics Scientist at CuraGen Corporation. and Bioinformatics.

Gainetdinov is the Institute of Translational Biomedicine Director at Saint Petersburg State University Technology in Genova, Italy (2008-2016) and an Associate Research Professor in the Department of Cell Biology Before joining the Department of Cell Biology in 1996 as a postdoc and becoming faculty at Duke in 2000