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Results found for "preclinical pharmacology"
- 📰 GPCR Weekly News, April 15 to 21, 2024
Samuel Hoare on Advanced data analysis for GPCR pharmacology, which will be held on Thursdays between Matchmaking Did you check out our first job opportunity spotlight for a Principal Scientist In Vitro Pharmacology , Mark Schmeizl, had a great conversation about this position with Beth Fleck, Director of In Vitro Pharmacology , 2024 | 11th Adhesion GPCR Workshop July 12 - 17, 2026 | 20th World Congress of Basic and Clinical Pharmacology 2026 GPCR Jobs NEW Postdoc Position Principal Scientist, In vitro pharmacology Senior Associate Scientist
- 📰 GPCR Weekly News, June 24 to 30, 2024
, 2024 | 11th Adhesion GPCR Workshop July 12 - 17, 2026 | 20th World Congress of Basic and Clinical Pharmacology 2026 GPCR Jobs NEW Scientist; Biochemistry, Cellular and Mechanistic Pharmacology; Lead Discovery and Director GPCR Drug Discovery Biologist HIGHLIGHT Principal Scientist, In vitro pharmacology Post-Doctoral Scientist- Molecular Pharmacology (FDE) Research Assistant Senior Scientist - Receptor Pharmacology
- 🤯Mind-blowing GPCR Scoops! Discover the Latest Breakthroughs! ⦿ Nov 18 - 24, 2024
Celebrating Excellence: Patrick Sexton and Arthur Christopoulos Named Among Top 1% of Scientists in Pharmacology novo antibodies look more like drugs GPCR Events, Meetings, and Webinars December 10 - 12, 2024 | Pharmacology | BIO International Convention 2025 July 12 - 17, 2026 | 20th World Congress of Basic and Clinical Pharmacology Principal Scientist, Medicinal Chemistry PhD fellowship in GPCR mechanosensing Senior Scientist, GPCR Pharmacology Research Associate - Professor Graeme Milligan Postdoc in Molecular Pharmacology - The Hauser Group
- 📰 GPCR Weekly News, March 4 to 10, 2024
Terry Kenakin's "Applying Pharmacology to Drug Discovery" course at Dr. pathways and two distinct high-affinity sites for succinate in succinate receptor 1/GPR91 Specific pharmacological , 2024 | 11th Adhesion GPCR Workshop July 12 - 17, 2026 | 20th World Congress of Basic and Clinical Pharmacology Research Unit Postdoctoral Scholar – Synaptic physiology, optical imaging, substance use disorder, pharmacology Research Fellow Postdoctoral Fellow – Molecular Pharmacology of Feeding Behavior Director of Laboratory
- Why Intracellular Drugs May Hold the Key to GPCR Therapeutics
This opens up a new pharmacological space—and a reason to revisit “failed” targets with fresh eyes. Persistent binding isn’t just about longer half-lives—it’s about smarter pharmacology. ahead with The Kenakin Brief — a concise, science‑first email update with the latest insights in GPCR pharmacology
- Applications of Fluorescent Probes in Confocal Imaging of GPCRs: From Live to Fixed Cells
High-Resolution Confocal Imaging of GPCRs To study the dynamics of GPCRs, the imaging method must be spatially precise This method is very precise at determining these parameters thanks to capturing fluorescence from a single studies, it facilitates the structural context necessary to map receptor localization in defined states (pharmacological Br J Pharmacol. 2023 Dec 12. doi: 10.1111/bph.16297.
- Unlocking the Future of Medicine: Advancements in GPCR Research
Course Schedule and Details Every Thursday at 10 am EST Principles of Pharmacology in Drug Discovery Candidate Molecules Dates: September 5th to 26th, 2024 Registrants will learn: Essentials of measuring pharmacologic Principles of Pharmacology in Drug Discovery II - Advanced Methods for the Optimization of Candidate , 2024 | 11th Adhesion GPCR Workshop July 12 - 17, 2026 | 20th World Congress of Basic and Clinical Pharmacology Discovery Biotherapeutics Post-Doctoral Fellow/Trainee Scientist; Biochemistry, Cellular and Mechanistic Pharmacology
- How GPCR Collaboration Built an Innovation Engine
What emerged wasn’t just another pharmacology group — it became a collaborative engine for GPCR discovery Turning Silos into Systems The early 2000s were not kind to exploratory pharmacology. Why This Matters GPCR research demands integration — pharmacology, structural biology, signaling pathways
- Is Your Agonist Really “Working”—Or Are You Just Seeing What Your System Allows?
In this eye-opening module, Terry Kenakin explores a concept that could change how you interpret pharmacological
- 📢 Early Bird Registration Ends Tomorrow! | Sep 16 - 22, 2024
This is your chance to get the whole experience of our comprehensive pharmacology courses for less! Topics: Pharmacologic activity measurement, mechanisms of action, and GPCR discovery strategies. Emerging Voices in GPCR Biology in Special Issue of Molecular Pharmacology GPCR Events, Meetings, and GPCRs-Targeted Drug Discovery Summit Europe July 12 - 17, 2026 | 20th World Congress of Basic and Clinical Pharmacology GPCR Jobs HIGHLIGHT Research Associate - Professor Graeme Milligan HIGHLIGHT Postdoc in Molecular Pharmacology
- What's Going On with GPCRs?! Find Out in This Week's Update! ⦿ Nov 4 - 10, 2024
Conference November 26 - 28, 2024 | GPCRs-Targeted Drug Discovery Summit Europe December 10 - 12, 2024 | Pharmacology | BIO International Convention 2025 July 12 - 17, 2026 | 20th World Congress of Basic and Clinical Pharmacology Principal Scientist, Medicinal Chemistry PhD fellowship in GPCR mechanosensing Senior Scientist, GPCR Pharmacology Research Associate - Professor Graeme Milligan Postdoc in Molecular Pharmacology - The Hauser Group
- How Breakthroughs Happen: Eric Trinquet on Innovation, Serendipity & GPCRs
Watch Episode 174 Most scientists are taught to aim for precision and control. yes—but also a deep partnership with GPCR legend Terry Kenakin to bridge industry credibility with pharmacological That opened the door to something rare in functional pharmacology: plate-based GPCR internalization tracking internalization of endogenous GLP-1 receptors in rat beta cells—with no overexpression, no imaging, and no pharmacological At early stages, breadth matters more than precision. Cast a wide net. Follow anomalies.
- Unlock the Hidden Complexity Behind GPCRs—From Terry Kenakin’s Vault
What if the way we've been studying GPCRs—arguably the most important drug targets in pharmacology—has
- 📰 GPCR Weekly News, February 19 to 25, 2024
GPCR University Today marks the conclusion of the Dr.GPCR University course, ‘Applying Pharmacology to Global’s Biologics event GPCR Events, Meetings, and Webinars February 20, 2024 | Career Opportunities in Pharmacology , 2024 | 11th Adhesion GPCR Workshop July 12 - 17, 2026 | 20th World Congress of Basic and Clinical Pharmacology Research Unit NEW Postdoctoral Scholar – Synaptic physiology, optical imaging, substance use disorder, pharmacology Research Fellow Postdoctoral Fellow – Molecular Pharmacology of Feeding Behavior Director of Laboratory
- 📰 GPCR Weekly News, February 13 to 19, 2023
(June 4 - 8, 2023). 2023 Molecular Pharmacology (GRS) Seminar GRC. (June 10 - 11, 2023). (June 11 - 16, 2023). 19th World Congress of Basic & Clinical Pharmacology 2023. drug design postdoc at the Department of Drug Design and Pharmacology Software / database development PhD student at Department of Drug Design and Pharmacology Software / database development postdoc at the Department of Drug Design and Pharmacology Postdoc in Bioinformatics/Data Science at Department
- 📰 GPCR Weekly News, February 20 to 26, 2023
(June 4 - 8, 2023). 2023 Molecular Pharmacology (GRS) Seminar GRC. (June 10 - 11, 2023). (June 11 - 16, 2023). 19th World Congress of Basic & Clinical Pharmacology 2023. Computational drug design postdoc at the Department of Drug Design and Pharmacology Software / database development PhD student at Department of Drug Design and Pharmacology Software / database development postdoc at the Department of Drug Design and Pharmacology Postdoc in Bioinformatics/Data Science at
- 📰 GPCR Weekly News, March 18 to 24, 2024
Role of pH-sensing receptors in colitis GPCRs in Oncology and Immunology Polarizing itch Biochemical pharmacology , 2024 | 11th Adhesion GPCR Workshop July 12 - 17, 2026 | 20th World Congress of Basic and Clinical Pharmacology Research Unit Postdoctoral Scholar – Synaptic physiology, optical imaging, substance use disorder, pharmacology Research Fellow Postdoctoral Fellow – Molecular Pharmacology of Feeding Behavior Director of Laboratory
- 📰 GPCR Weekly News, February 27 to March 5, 2023
(June 4 - 8, 2023). 2023 Molecular Pharmacology (GRS) Seminar GRC. (June 10 - 11, 2023). Computational drug design PhD student at the Department of Drug Design and Pharmacology. Computational drug design postdoc at the Department of Drug Design and Pharmacology. Software / database development PhD student at Department of Drug Design and Pharmacology. Software / database development postdoc at the Department of Drug Design and Pharmacology.
- 📰 GPCR Weekly News, January 30 to February 5, 2023
Pharmacological characterization of novel small molecule agonists and antagonists for the orphan receptor (June 4 - 8, 2023). 2023 Molecular Pharmacology (GRS) Seminar GRC. (June 10 - 11, 2023). (June 11 - 16, 2023). 19th World Congress of Basic & Clinical Pharmacology 2023. PhD student at Department of Drug Design and Pharmacology Software / database development postdoc at the Department of Drug Design and Pharmacology Postdoc in Bioinformatics/Data Science at Department
- 📰 GPCR Weekly News, April 1 to 7, 2024
Samuel Hoare on Advanced data analysis for GPCR pharmacology, which will be held on Thursdays between , 2024 | 11th Adhesion GPCR Workshop July 12 - 17, 2026 | 20th World Congress of Basic and Clinical Pharmacology Research Unit Postdoctoral Scholar – Synaptic physiology, optical imaging, substance use disorder, pharmacology Research Fellow Postdoctoral Fellow – Molecular Pharmacology of Feeding Behavior Join Dr.
- How a Failed Med School Dream Sparked a GPCR Biotech Revolution
His work spans deep academic research, startup life, and the application of machine learning and pharmacology Superluminal Medicines: AI/ML Meets GPCR Pharmacology As Ajay continued to explore how GPCR signaling Despite decades of progress in structural biology and pharmacology, predicting how a GPCR will respond computationally predictable, Ajay and his team are working to reduce the time and cost of developing new, more precise The ability to ask precise, translational questions is just as important as having technical expertise
- 📰 GPCR Weekly News - January 2 to 8, 2023
Pharmacological Profiling of a Brugia malayi Muscarinic Acetylcholine Receptor as a Putative Antiparasitic Deadline February 12, 2023 Current Technologies To Understand G-Protein-Coupled Receptor Molecular Pharmacology June 4-8,2023. 2023 Molecular Pharmacology (GRS) Seminar GRC. June 10 - 11. June 11-16, 2023. 19th World Congress of Basic & Clinical Pharmacology 2023. July 2 - 7. Biotechnology and Biological Sciences Doctoral Training Programme Senior QM Manager Director of Molecular Pharmacology
- Accelerating GPCR Drug Discovery
For over two decades, my work has centered on GPCR pharmacology . My Approach: Biology, Execution, Systems My consulting approach uniquely blends deep pharmacology expertise
- 📰 GPCR Weekly News, May 29 to June 4, 2023
This week, we would like to highlight two new publications: Pharmacological hallmarks of allostery at We look forward to seeing you in a few days at the Molecular Pharmacology GRC and the associated Molecular Pharmacology GRS in Switzerland. Pharmacological inhibition of neuropeptide Y receptors Y1 and Y5 reduces hypoxic breast cancer migration Structural and Molecular Insights into GPCR Function Pharmacological hallmarks of allostery at the M4
- 📰 GPCR Weekly News
GPCRs in Neuroscience CGRP physiology, pharmacology, and therapeutic targets: Migraine and beyond. Exploring pharmacological inhibition of Gq/11 as an analgesic strategy. Current Technologies To Understand G-Protein-Coupled Receptor Molecular Pharmacology. June 4-8,2023. 2023 Molecular Pharmacology (GRS) Seminar GRC. June 10 - 11. June 11-16, 2023. 19th World Congress of Basic & Clinical Pharmacology 2023. July 2 - 7.
- High-Content Screening for GPCR Programs: Overcoming Assay Limitations with Fluorescent Ligands
where receptor trafficking, spatial dynamics, and context-dependent signaling significantly influence pharmacology for Modern Screening Needs Radioligand binding assays have historically been the standard for GPCR pharmacology , preserving receptor conformation, trafficking, and native membrane context—key variables for GPCR pharmacology High-Content Binding Assays In CB2-expressing HEK cells, the fluorescent ligand CELT-331 produces precise For teams working in GPCR pharmacology or cannabinoid research, these tools accelerate hit validation
- 📰 GPCR Weekly News, March 11 to 17, 2024
Terry Kenakin's "Applying Pharmacology to Drug Discovery" course at Dr. , 2024 | 11th Adhesion GPCR Workshop July 12 - 17, 2026 | 20th World Congress of Basic and Clinical Pharmacology Research Unit Postdoctoral Scholar – Synaptic physiology, optical imaging, substance use disorder, pharmacology Research Fellow Postdoctoral Fellow – Molecular Pharmacology of Feeding Behavior Director of Laboratory
- Targeted Drug Design through GPCR Mutagenesis: Insights from β2AR
The study focused on two critical pharmacological properties: efficacy and potency. β2AR residues that influence efficacy and potency, pharmaceutical researchers can create drugs that precisely distinction is essential for designing drugs that selectively target these residues to achieve desired pharmacological The identification of pharmacologically significant residues enables more accurate predictions of how
- Why Sokhom Pin Never Left GPCRs, Even When Everyone Else Did
refining assays, exploring signaling bias, and building a robust knowledge base in one of the most pharmacologically
- Mechanism vs. Assumption: A Model-First Path to Getting GPCR MoA Right
That’s precisely what Terry’s Corner delivers every week: practical tools from Dr. Associate; Senior Scientist, Data Science—curated roles aligned to GPCR discovery and translational pharmacology GPCR scientists, translational pharmacologists, biotech discovery teams, platform company leaders, and Access this week’s full Premium Edition here ➤ What our members say 🗣️ "The best pharmacology teacher Also super-valuable for those of us learning how to teach pharmacology." — DrGPCR University Attendee



















