Search Results

Moro , a medicinal chemist who introduced him to the interplay between molecular structure and biological He began exploring how small modifications could radically alter biological outcomes, an insight that The realization that he could ask—and answer—complex biological questions with a computer sealed the

insights from major conferences, emerging research, and expert commentary Whether you’re a pharmacologist, biotech GPCR scientists, translational pharmacologists, biotech drug discovery teams, and decision-makers who

“So I had to understand the biology myself.”

Often, a low EC50 indicates high potency, but this isn't always the case due to various biological factors This knowledge can guide modifications to improve binding affinity and bioavailability.

I've seen this pattern unfold across biotech, academia, and nonprofits. My Approach: Biology, Execution, Systems My consulting approach uniquely blends deep pharmacology expertise Here's how I bring a fresh perspective: Biology-First, Data-Driven Strategy:  I help you focus on the

Hidden Cost of Good Science Without Systems I’ve seen this pattern again and again—across academia, biotech This is embedded consulting for biotech and VC teams who need to move fast —without compromising scientific Here’s what I bring: Biology-First Strategy I’ve designed GPCR assays, led collaborations across research Who I Work With ✅ Biotech Teams  – Especially those lacking in-house GPCR leads or overwhelmed by CRO assets in their portfolio. ✅ Contract Research Organizations (CROs)  – Wanting to better align with biotech

work at Alkermes didn’t just improve drug screening outcomes, it redefined what great leadership in biotech

His hybrid path is a model of possibility for professionals in the biotech industry who still dream of

Plus: must-read chemokine and PTH1R papers, and new momentum across biotech—from Superluminal to Neurocrine With a biology-first strategy, embedded execution, and scalable systems, it turns scattered data into

uncover why efficacy is the unsung hero of drug discovery and how its effects depend entirely on the biological

Explore this week’s research, tools, and biotech insights in one place.

You’ll uncover: Why pharmacology is the glue between chemistry and biology How to interpret drug behavior

researchers to explore different linker positions, tailor activity (agonist or antagonist), and retain biological Maria emphasizes the importance of genuinely listening to researchers: understanding the biological question “We want to illuminate biology. That’s the mission. ” — Dr.

Tools The Story Behind Celtarys – From Chemistry to Company   How does a medicinal chemist become a biotech Explore this week’s research, tools, and biotech insights in one place.

specialization in pharmaceutical chemistry, a degree that allowed her to see the full picture from synthesis to biology

Watch Episode 168 What does it take for a scientist to become a startup leader in biotech? For Dr. Over time, she developed a fascination with how molecules influence biology and how that chemistry could

“The students of today want biosensors, miniaturization, and multiplexing.

.” — Tom Sakmar This makes them more than biomarkers — they’re potential drivers of disease .

Celtarys Research develops high-quality, fluorescently labeled ligands and innovative chemical biology analysis, and live-cell imaging, empowering both academic and industrial scientists to uncover GPCR biology will help accelerate the adoption of our chemical tools and foster collaborations that turn receptor biology GPCR empowers scientists and companies advancing receptor biology and drug discovery. About Celtarys Research Celtarys Research is a biotech company based in Spain that specializes in the

year trajectory in motion, culminating in a scalable, multiplexed platform to investigate GPCR-RAMP biology Why It Matters This isn’t just a dataset, it’s a shift in how GPCR biology is approached : Study known

Access the Course Hacking GPCRs: A Toolkit for Systems Biology – New Podcast Episode In Episode 167, to scalable multiplex assays, this conversation dives deep into the tools now transforming receptor biology—and Explore this week’s research, tools, and biotech insights in one place.

Explore this week’s research, tools, and biotech insights in one place.

GPCR tools and key moves in the biotech world. Dr. Explore this week’s research, tools, and biotech insights in one place.

Meanwhile, the industry is moving fast with AI-powered platforms, bold leadership moves, and strategic biotech Explore this week’s research, tools, and biotech insights in one place.

resulting phenotype, researchers can identify essential domains and residues crucial for the protein's biological directions will likely focus on enhancing its scalability, accuracy, and applicability across broader biological Another promising development is the application of DMS to a wider array of biological systems, including Trends in Biotechnology , 29 (9), 435–442. https://doi.org/10.1016/j.tibtech.2011.04.003 Fowler, D. BioRxiv (Cold Spring Harbor Laboratory) . https://doi.org/10.1101/2024.04.17.590000 Pines, G., Fankhauser

School of Medicine to Receive $3-Million Award from ARPA-H’s Sprint for Women’s Health Nxera Pharma Wins Biotech Year and Financing Deal of the Year at the Citeline Japan Awards 2024 GPCR therapies: Eight promising biotechs hacking the cell signaling pathway From Structure to Solution: How Structural Biology Informs the Development of Drugs Targeting G Protein-Coupled Receptors Olfactive Biosolutions Establishes Scientific Advisory Emerging Voices in GPCR Biology in Special Issue of Molecular Pharmacology GPCR Events, Meetings, and

Research using techniques like bioluminescence resonance energy transfer (BRET) and fluorescence resonance This insight not only enhances our understanding of class B1 GPCR biology but also opens new avenues Current Opinion in Structural Biology, 2023. 80 : p. 102574. 2.         

investigate G protein-coupled receptor signaling kinetics and concentration-dependent responses using ONE-GO biosensors Pharmaceuticals Announces October 2024 Inducement Grants Under Nasdaq Listing Rule 5635(c)(4) Neurocrine Biosciences Emerging Voices in GPCR Biology in Special Issue of Molecular Pharmacology GPCR Events, Meetings, and Pharmacology - The Hauser Group Postdoctoral Scholar – iPSC in cardiac and endothelial cell function Protein Biochemist /Structural Biologist Senior Scientist/Staff Scientist, Computational Chemistry Postdoc in GPCR mechanosensing

passion, and interact with your exceptional peers to explore the latest advancements in adhesion GPCR biology Emerging Voices in GPCR Biology in Special Issue of Molecular Pharmacology GPCR Events, Meetings, and /Structural Biologist Senior Scientist/Staff Scientist, Computational Chemistry Postdoc in GPCR mechanosensing Identification of immune-related hub genes in spinal cord injury GPCRs in Oncology and Immunology Biochemical GPCR Research Protocol for detecting endogenous GPCR activity in primary cell cultures using ONE-GO biosensors

Molecular basis of proton-sensing by G protein-coupled receptors. bioRxiv .