. << Back to podcast list Strategic Partner(s) Leadership, Impact, and GPCR Signaling with Dr. early discoveries in cyclic AMP signaling to uncovering ultrasensitive receptor responses at femtomolar ligand The moment when femtomolar ligand concentrations uncovered unexpected receptor sensitivity. Why It Might Hit Home If you’ve ever: Faced unexpected assay behavior at ultra-low ligand concentrations More about Michelle Halls Monash Institute of Pharmaceutical Sciences Bluesky LinkedIn Articles about

. << Back to podcast list Strategic Partner(s) Qing Fan: Inside the Architecture of Class C GPCRs Class Unlike class A receptors, which bind orthosteric ligands within their transmembrane domain and can function Mutational analysis of the GABA-B2-bound lipid site further suggested that lipid acts as a negative allosteric "Ligands that display biased signaling property may serve as highly specific drug candidates. Fan at Columbia University Research Gate LinkedIn Pubmed Dr. GPCR Ecosystem Unlock the Full Dr.

<< Back to podcast list Strategic Partner(s) Murat Tunaboylu & Ben Holland About Murat Tunaboylu "Murat Murat Tunaboylu on the web Antiverse DSV Future of Drug Discovery Podcast Twist Bioscience LinkedIn Twitter pursued international strategic partnerships, managed IP matters, helped establish a manufacturing line GPCR Learning Ecosystem ✔ Full Masterclass library ✔ Terry's Pharmacology Corner ✔ Advanced GPCR courses ✔ Scientific discussions → Become Premium Upcoming Live Expert Sessions ➚ 🔒Explore the Full Masterclass

<< Back to podcast list Strategic Partner(s) Dr. Bruno Giros About Dr. Bruno Giros Dr. Bruno Giros on the web Dougles Research Center LinkedIn Google Scholar Researchgate Dr. GPCR Learning Ecosystem ✔ Full Masterclass library ✔ Terry's Pharmacology Corner ✔ Advanced GPCR courses ✔ Scientific discussions → Become Premium Upcoming Live Expert Sessions ➚ 🔒Explore the Full Masterclass big difference. ★ Review on Apple Podcasts ★ Rate on Spotify ✉️ Send feedback to the team Thanks for listening

<< Back to podcast list Strategic Partner(s) Dr. Marta Filizola About Dr. Marta Filizola Dr. Marta Filizola on the web Icahn School of Medicine at Mount Sinai Filizola Lab Wikipedia Twitter Linkedin GPCR Learning Ecosystem ✔ Full Masterclass library ✔ Terry's Pharmacology Corner ✔ Advanced GPCR courses ✔ Scientific discussions → Become Premium Upcoming Live Expert Sessions ➚ 🔒Explore the Full Masterclass big difference. ★ Review on Apple Podcasts ★ Rate on Spotify ✉️ Send feedback to the team Thanks for listening

<< Back to podcast list Strategic Partner(s) Dr. Richard Premont About Dr. Richard Premont "Dr. University of New York) in 1990 and 1992, working with Ravi Iyengar on regulation/desensitization of the liver in Gastroenterology, where he remained until 2018 studying GPCRs and their signaling pathways in the liver and in liver disease. Richard Premont on the web Google Scholar LinkedIn Dr. GPCR Unlock the Full Dr.

<< Back to podcast list Strategic Partner(s) Dr. Roger Sunahara About Dr. This is an important perspective in the pursuit of receptor subtype-specific ligands, a major aspect One example of our recent work surrounds a structure-based effort to develop ligands that specifically We have identified several GPCR ligands that allosterically modulate orthosteric ligand binding and target Roger Sunahara on the web UCSD Profile Google Scholar ResearchGate LinkedIn Dr.

<< Back to podcast list Strategic Partner(s) GPCR location matters with Dr. the nanoscale spatial organization of G protein-coupled receptors (GPCRs) at the plasma membrane of living Gabriele Kockelkoren on the web Stanford University X LinkedIn Google Scholar ORCID ResearchGate Unlock GPCR Learning Ecosystem ✔ Full Masterclass library ✔ Terry's Pharmacology Corner ✔ Advanced GPCR courses ✔ Scientific discussions → Become Premium Upcoming Live Expert Sessions ➚ 🔒Explore the Full Masterclass

. << Back to podcast list Strategic Partner(s) Sam Hoare: Receptor Residence Time and GPCR Data Analysis Which ligand binds tightest, ranks highest, earns the most attention in an SAR campaign. Samuel Hoare on the web Pharmechanics LLC LinkedIn Pubmed Google Scholar YouTube Dr. GPCR Learning Ecosystem ✔ Full Masterclass library ✔ Terry's Pharmacology Corner ✔ Advanced GPCR courses ✔ Scientific discussions → Become Premium Upcoming Live Expert Sessions ➚ 🔒Explore the Full Masterclass

. << Back to podcast list Strategic Partner(s) Antony Boucard: Adhesion GPCRs and the Molecular Code 1,000 amino acids, autoproteolytic cleavage at the membrane, and a near-total absence of characterized ligands of Thomas Südhof at UT Southwestern and Stanford University, where he made the initial observation linking And whether you're there for a short time or for the rest of your life, you'll have the best time of your life during the time you're doing it."

<< Back to podcast list Strategic Partner(s) Brendan Wilkins About Brendan Wilkins "Brendan completed This project aims to characterise the molecular pharmacology of GPR146 and to validate the proposed ligands of GPR146 in line with IUPHAR-NC guidelines on deorphanisation of orphan GPCRs. GPCR Learning Ecosystem ✔ Full Masterclass library ✔ Terry's Pharmacology Corner ✔ Advanced GPCR courses ✔ Scientific discussions → Become Premium Upcoming Live Expert Sessions ➚ 🔒Explore the Full Masterclass

<< Back to podcast list Strategic Partner(s) Dr. Peter Robert Banks About Dr. providing scientific guidance to the senior management team on new technology and emerging trends impacting life Peter Robert Banks on the web LinkedIn Dr. GPCR Ecosystem Unlock the Full Dr. GPCR Learning Ecosystem ✔ Full Masterclass library ✔ Terry's Pharmacology Corner ✔ Advanced GPCR courses ✔ Scientific discussions → Become Premium Upcoming Live Expert Sessions ➚ 🔒Explore the Full Masterclass

<< Back to podcast list Strategic Partner(s) Julia Gardner About Julia Gardner Julia is a senior undergraduate Julia Gardner on the web Rajagopal Lab Google Scholar ResearchGate LinkedIn Dr. GPCR Learning Ecosystem ✔ Full Masterclass library ✔ Terry's Pharmacology Corner ✔ Advanced GPCR courses ✔ Scientific discussions → Become Premium Upcoming Live Expert Sessions ➚ 🔒Explore the Full Masterclass big difference. ★ Review on Apple Podcasts ★ Rate on Spotify ✉️ Send feedback to the team Thanks for listening

<< Back to podcast list Strategic Partner(s) The Role of Quantitative Sciences in GPCRs with Dr. Nagarajan Vaidehi on the web City of Hope Google Scholar LinkedIn Dr. GPCR Unlock the Full Dr. GPCR Learning Ecosystem ✔ Full Masterclass library ✔ Terry's Pharmacology Corner ✔ Advanced GPCR courses ✔ Scientific discussions → Become Premium Upcoming Live Expert Sessions ➚ 🔒Explore the Full Masterclass big difference. ★ Review on Apple Podcasts ★ Rate on Spotify ✉️ Send feedback to the team Thanks for listening

<< Back to podcast list Strategic Partner(s) Irfan Dhanidina, Dr. Kathleen Caron and Dr. who translate important GPCR research into novel therapies for patients. " Irfan Dhanidina on the web LinkedIn These ligands stimulate receptor β-arrestin recruitment without activating canonical G protein signaling Critically, these ligands reduce addiction-associated behaviors in animal models without the side effects Lauren Slosky on the web University of Minnesota Department Page Twitter LinkedIn Google Scholar PubMed

• Pharmacology frameworks used in modern drug discovery • Monthly live AMA discussions with Terry Kenakin Stay connected on LinkedIn and YouTube . Pharmacology Core Emerging Drug Hunter — Expand Your Edge Expert-Level Mastery — Advanced Pharmacology Live

<< Back to podcast list Strategic Partner(s) Dr. Raul Gainetdinov About Dr. Gainetdinov was included in the Web of Science (WOS) Highly Cited Researchers (HCR) list, representing GPCR Learning Ecosystem ✔ Full Masterclass library ✔ Terry's Pharmacology Corner ✔ Advanced GPCR courses ✔ Scientific discussions → Become Premium Upcoming Live Expert Sessions ➚ 🔒Explore the Full Masterclass big difference. ★ Review on Apple Podcasts ★ Rate on Spotify ✉️ Send feedback to the team Thanks for listening

<< Back to podcast list Strategic Partner(s) Dr. Aylin Hanyaloglu About Dr. Aylin Hanyaloglu Dr. Aylin Hanyaloglu on the web LinkedIn Researchgate Twitter Imperial College London Elsevier Loop Dr. GPCR Learning Ecosystem ✔ Full Masterclass library ✔ Terry's Pharmacology Corner ✔ Advanced GPCR courses ✔ Scientific discussions → Become Premium Upcoming Live Expert Sessions ➚ 🔒Explore the Full Masterclass big difference. ★ Review on Apple Podcasts ★ Rate on Spotify ✉️ Send feedback to the team Thanks for listening

. << Back to podcast list Strategic Partner(s) GPCR Pharmacology, Career Twists & Serendipity with Sokhom executed a PhD entirely in the industry setting—efficient, targeted, and rooted in real-world projects like The Lifecycle of GPCR Popularity Sokhom has witnessed the waves of scientific fashion: “There was a time Lessons from Molecules and Mentors He draws inspiration from scientific complexity and colleagues like Sokhom Pin on the web LinkedIn Unlock the Full Dr.

<< Back to podcast list Strategic Partner(s) Dr. Patrick Sexton About Dr. biased agonism, and also on allosteric interactions between GPCRs and other proteins and small molecule ligands GPCR Learning Ecosystem ✔ Full Masterclass library ✔ Terry's Pharmacology Corner ✔ Advanced GPCR courses ✔ Scientific discussions → Become Premium Upcoming Live Expert Sessions ➚ 🔒Explore the Full Masterclass big difference. ★ Review on Apple Podcasts ★ Rate on Spotify ✉️ Send feedback to the team Thanks for listening

<< Back to podcast list Strategic Partner(s) Dr. Silvia Sposini About Dr. Silvia Sposini on the web Bordeaux Neurocampus LinkedIn ResearchGate X (Twitter) Dr. GPCR Learning Ecosystem ✔ Full Masterclass library ✔ Terry's Pharmacology Corner ✔ Advanced GPCR courses ✔ Scientific discussions → Become Premium Upcoming Live Expert Sessions ➚ 🔒Explore the Full Masterclass big difference. ★ Review on Apple Podcasts ★ Rate on Spotify ✉️ Send feedback to the team Thanks for listening

<< Back to podcast list Strategic Partner(s) Dr. Josh Pottel About Dr. Josh Pottel on the web Molecular Forecaster LinkedIn BlueSky Google Scholar Twitter Dr. GPCR Learning Ecosystem ✔ Full Masterclass library ✔ Terry's Pharmacology Corner ✔ Advanced GPCR courses ✔ Scientific discussions → Become Premium Upcoming Live Expert Sessions ➚ 🔒Explore the Full Masterclass big difference. ★ Review on Apple Podcasts ★ Rate on Spotify ✉️ Send feedback to the team Thanks for listening

<< Back to podcast list Strategic Partner(s) Dr. Davide Calebiro About Dr. based on FRET and single-molecule microscopy, which allow them to directly observe signalling events in living Davide Calebiro on the web University of Birmingham Twitter Google Scholar LinkedIn Dr. GPCR Learning Ecosystem ✔ Full Masterclass library ✔ Terry's Pharmacology Corner ✔ Advanced GPCR courses ✔ Scientific discussions → Become Premium Upcoming Live Expert Sessions ➚ 🔒Explore the Full Masterclass

<< Back to podcast list Strategic Partner(s) Dr. G. Aditya Kumar About Dr. G. Aditya Kumar Dr. Aditya Kumar on the web University of Michigan Puthenveedu Lab Google Scholar NIH ORCID LinkedIn Twitter GPCR Learning Ecosystem ✔ Full Masterclass library ✔ Terry's Pharmacology Corner ✔ Advanced GPCR courses ✔ Scientific discussions → Become Premium Upcoming Live Expert Sessions ➚ 🔒Explore the Full Masterclass big difference. ★ Review on Apple Podcasts ★ Rate on Spotify ✉️ Send feedback to the team Thanks for listening

<< Back to podcast list Strategic Partner(s) The Scientist's Compass: From Academia to Entrepreneurship transitioned from biophysics and protein folding to cannabinoid receptor research, guided by key mentors like Dmitry Veprintsev on the web LinkedIn Veprintsev Lab Z7 Biotech University of Nottingham Unlock the Full GPCR Learning Ecosystem ✔ Full Masterclass library ✔ Terry's Pharmacology Corner ✔ Advanced GPCR courses ✔ Scientific discussions → Become Premium Upcoming Live Expert Sessions ➚ 🔒Explore the Full Masterclass

. << Back to podcast list Strategic Partner(s) Randy Hall: Adhesion GPCRs and the Tail Nobody Wanted tethered agonist model his lab proposed in 2011, and why a family once dismissed as undruggable now looks like The experiment that did the opposite Predicting that an endogenous ligand acted on the large N terminus in the early 1990s, research with no clinical intent that became the template for explaining a long list GUEST LINKS - Hall Lab: http://www.pharm.emory.edu/hall/index.html - LinkedIn: https://www.linkedin.com

. << Back to podcast list Strategic Partner(s) Fiona Marshall: Three Decades Inside GPCR Drug Discovery It also confronts where the field still struggles — translating biased agonism from cell line to clinic The Ligand That Wasn't the Ligand Screening orphan receptors in yeast, the team chased peptide hits that So it turned out that the ligands were not the peptides at all." Fiona Marshall on the web LinkedIn Twitter Google Scholar MSD UK Dr.

<< Back to podcast list Strategic Partner(s) A Brief History of allosteric modulation with Dr. Arthur Christopoulos on the web Monash University Wikipedia Google Scholar LinkedIn Dr. Arthur explained the concept of endogenous allosteric ligands and the possibility of using a neutral allosteric ligand as a preferred therapeutic approach, emphasizing the importance of looking for low They also discussed the potential of certain drugs, like flumazenil, as 'nails' or compounds that could

<< Back to podcast list Strategic Partner(s) Dr. Nicola J. Smith About Dr. Nicola J. Smith Dr. Together with Irina Kufareva , UCSD, her team developed a novel approach to identifying ligands for orphan GPCRs by developing a powerful new computational tool for identifying ‘surrogate’ ligands (borrowed Smith on the web UNSW Sydney LinkedIn Retraction Watch Twitter Dr. GPCR Learning Ecosystem ✔ Full Masterclass library ✔ Terry's Pharmacology Corner ✔ Advanced GPCR courses

<< Back to podcast list Strategic Partner(s) Dr. Hannes Schihada About Dr. development of FRET/BRET -based GPCR conformational biosensors, which can be employed in high throughput ligand Hannes Schihada on the web Karolinska Institutet Twitter Adher´n Rise LinkedIn Dr. GPCR Learning Ecosystem ✔ Full Masterclass library ✔ Terry's Pharmacology Corner ✔ Advanced GPCR courses ✔ Scientific discussions → Become Premium Upcoming Live Expert Sessions ➚ 🔒Explore the Full Masterclass