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Live webinar with Dr. Drug Candidates G protein-coupled receptors can signal through multiple intracellular pathways, and ligands It is a consequence of ligand-dependent receptor conformations and allosteric probe dependence, and it The Biology Behind Bias Ligands produce differential pathway engagement at a single receptor because GPCR membership gives you access to all upcoming live, interactive webinars. Free.

. << Back to podcast list Strategic Partner(s) Amynah Pradhan: The Delta Opioid Receptor and the Migraine For her, this line of work is also personal — the delta opioid receptor has been her scientific focus and directed at forebrain circuits where emotional salience of pain lives. Brigitte Kieffer , where she studied ligand-directed signaling at the delta-opioid receptor. Amynah Pradhan on the web Lab page LinkedIn Twitter Google Scholar PubMed Dr.

. << Back to podcast list Strategic Partner(s) Visualizing GLP-1 & GIP Receptors in Islets and Brain team develops fluorescence-based and chemically engineered tools to study gpcr internalization and ligand in metabolic tissues What collaborative chemistry enabled in designing receptor-targeted fluorescent ligands metabolic therapies may evolve based on receptor cross-talk and tissue-specific engagement Who should listen GPCR Learning Ecosystem ✔ Full Masterclass library ✔ Terry's Pharmacology Corner ✔ Advanced GPCR courses

<< Back to podcast list Strategic Partner(s) Dr. Victoria Rasmussen on the web Tri-Institutional PhD Program in Chemical Biology Rockefeller University LinkedIn Madelyn Moore on the web MPaT PubMed LinkedIn Dr. GPCR Unlock the Full Dr. GPCR Learning Ecosystem ✔ Full Masterclass library ✔ Terry's Pharmacology Corner ✔ Advanced GPCR courses ✔ Scientific discussions → Become Premium Upcoming Live Expert Sessions ➚ 🔒Explore the Full Masterclass

<< Back to podcast list Strategic Partner(s) Dr. Benjamin Myers About Dr. These studies have revealed new and unexpected ways for membrane lipids to regulate GPCR activity and operate within the primary cilium, a tiny antenna-shaped structure at the cell surface with critical links GPCR Learning Ecosystem ✔ Full Masterclass library ✔ Terry's Pharmacology Corner ✔ Advanced GPCR courses ✔ Scientific discussions → Become Premium Upcoming Live Expert Sessions ➚ 🔒Explore the Full Masterclass

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Pfleger on NanoBRET live-cell assays, receptor complex pharmacology, and what it took to move GPCR biology from HEK cells to phase 2 clinical trials. << Back to podcast list Strategic Partner(s) Pfleger: NanoBRET But in living tissue, GPCRs do not operate alone - they form dynamic complexes with other receptors, scaffold proteins, and cytoskeletal components, and those interactions reshape conformation, ligand binding The development of NanoBRET - including live-cell ligand binding assays built on CRISPR-expressed receptors

<< Back to podcast list Strategic Partner(s) Dr. Katarina Nemec About Dr. Katarina Nemec on the web Babu Lab ResearchGate Google Scholar ORCID LinkedIn Twitter Dr. GPCR Learning Ecosystem ✔ Full Masterclass library ✔ Terry's Pharmacology Corner ✔ Advanced GPCR courses ✔ Scientific discussions → Become Premium Upcoming Live Expert Sessions ➚ 🔒Explore the Full Masterclass big difference. ★ Review on Apple Podcasts ★ Rate on Spotify ✉️ Send feedback to the team Thanks for listening

. << Back to podcast list Strategic Partner(s) Dr. He came to this field because a signaling cascade felt like a puzzle he could not stop thinking about Listeners will get a concrete look at what it means to modulate opioid pharmacology downstream of the receptor — and why the safety margins the field has been chasing for decades might actually live there Current lines of work include isoform-selective HSP90 inhibition as a strategy for widening the opioid

<< Back to podcast list Strategic Partner(s) Dr. Richard Premont About Dr. Richard Premont "Dr. University of New York) in 1990 and 1992, working with Ravi Iyengar on regulation/desensitization of the liver in Gastroenterology, where he remained until 2018 studying GPCRs and their signaling pathways in the liver and in liver disease. Richard Premont on the web Google Scholar LinkedIn Dr. GPCR Unlock the Full Dr.

<< Back to podcast list Strategic Partner(s) Dr. Daniel Isom About Dr. Daniel Isom on the web Isom Lab University of Miami Miller School of Medicine LinkedIn X (Twitter) BlueSky GPCR Learning Ecosystem ✔ Full Masterclass library ✔ Terry's Pharmacology Corner ✔ Advanced GPCR courses ✔ Scientific discussions → Become Premium Upcoming Live Expert Sessions ➚ 🔒Explore the Full Masterclass big difference. ★ Review on Apple Podcasts ★ Rate on Spotify ✉️ Send feedback to the team Thanks for listening

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<< Back to podcast list Strategic Partner(s) Dr. Claudia Stäubert About Dr. Claudia Stäubert on the web Stäubert Lab, Rudolf Schönheimer Institute of Biochemistry Leipzig LinkedIn They briefly touched upon the link between GPCRs and diseases, such as diabetes, but did not delve into GPCR Learning Ecosystem ✔ Full Masterclass library ✔ Terry's Pharmacology Corner ✔ Advanced GPCR courses ✔ Scientific discussions → Become Premium Upcoming Live Expert Sessions ➚ 🔒Explore the Full Masterclass

. << Back to podcast list Strategic Partner(s) Foord: Serendipity, RAMPs, And Industrial GPCR Pharmacology than a single seven-transmembrane protein, reshaping thinking about peptide receptor activation and ligand Foord reflects on the limits and promise of human genetics, the underexploited potential of GPCR antibodies ’s early large-scale genetics initiative, integrating GPCR targets, ion channels, transporters, and ligands Foord describes a period where his group repeatedly identified ligands for orphan receptors: the second

. << Back to podcast list Strategic Partner(s) Xylazine, Fentanyl, and the Fight for Breath with Catherine The methods used to measure respiratory depression in live models. How loss and lived experience can sharpen scientific focus. Who Should Listen This episode is especially relevant for: GPCR drug discovery scientists Respiratory Catherine Demery on the web LinkedIn Google Scholar University of Michigan 🎧 Listen now and see how

. << Back to podcast list Strategic Partner(s) GPCRs and the Science Behind Pain and Recovery with Dr In his words: “She let me run projects like a junior PI.” and CNS-associated ones—are often downplayed in pain research, with most focus on ionotropic targets like “She [Vanna] gave me a crash course in what it’s like to be a junior PI. Alex Serafini on the web LinkedIn Unlock the Full Dr.

<< Back to podcast list Strategic Partner(s) Dr. Caron Tribute Part 3 About Marc Caron Dr. GPCR Learning Ecosystem ✔ Full Masterclass library ✔ Terry's Pharmacology Corner ✔ Advanced GPCR courses ✔ Scientific discussions → Become Premium Upcoming Live Expert Sessions ➚ 🔒Explore the Full Masterclass big difference. ★ Review on Apple Podcasts ★ Rate on Spotify ✉️ Send feedback to the team Thanks for listening

<< Back to podcast list Strategic Partner(s) Dr. Kathleen Caron About Kathleen M. Caron Kathleen M. GPCR Learning Ecosystem ✔ Full Masterclass library ✔ Terry's Pharmacology Corner ✔ Advanced GPCR courses ✔ Scientific discussions → Become Premium Upcoming Live Expert Sessions ➚ 🔒Explore the Full Masterclass big difference. ★ Review on Apple Podcasts ★ Rate on Spotify ✉️ Send feedback to the team Thanks for listening

<< Back to podcast list Strategic Partner(s) Dr. Yamina Berchiche About Dr. Yamina Berchiche Dr. developed expertise over the past two decades studying structure/function relationships of GPCRs using live-cell Yamina Berchiche on the web Website LinkedIn Facebook Twitter ResearchGate PubMed Google Scholar Dr. GPCR Learning Ecosystem ✔ Full Masterclass library ✔ Terry's Pharmacology Corner ✔ Advanced GPCR courses ✔ Scientific discussions → Become Premium Upcoming Live Expert Sessions ➚ 🔒Explore the Full Masterclass

<< Back to podcast list Strategic Partner(s) Dr. Nicholas Holliday About Dr. receptor kinetics, signaling, and trafficking and on using novel imaging techniques, such as fluorescent ligands Nicholas Holliday on the web LinkedIn ORCID University of Nottingham Twitter Excellerate Bio Dr. GPCR Learning Ecosystem ✔ Full Masterclass library ✔ Terry's Pharmacology Corner ✔ Advanced GPCR courses ✔ Scientific discussions → Become Premium Upcoming Live Expert Sessions ➚ 🔒Explore the Full Masterclass

<< Back to podcast list Strategic Partner(s) Dr. Sudha Shenoy About Dr. Sudha Shenoy Dr. Sudha Shenoy LinkedIn Pubmed Dr. GPCR Ecosystem Unlock the Full Dr. GPCR Learning Ecosystem ✔ Full Masterclass library ✔ Terry's Pharmacology Corner ✔ Advanced GPCR courses ✔ Scientific discussions → Become Premium Upcoming Live Expert Sessions ➚ 🔒Explore the Full Masterclass big difference. ★ Review on Apple Podcasts ★ Rate on Spotify ✉️ Send feedback to the team Thanks for listening

<< Back to podcast list Strategic Partner(s) Dr. Aurélien Rizk About Dr. Aurélien Rizk "Dr. Aurélien Rizk on the web InterAx Biotech Paul Scherrer Institut The Org LinkedIn Google Scholar Dr. They highlighted the strategic importance of planning in the biotech sector due to limited funds and Technology Evolution and Ligand Residence Time Prediction Yamina Berchiche and Aurelien Rizk discussed The conversation also revolved around the company's ability to predict the residence time of a ligand

<< Back to podcast list Strategic Partner(s) Dr. Richard Premont About Dr. Richard Premont "Dr. University of New York) in 1990 and 1992, working with Ravi Iyengar on regulation/desensitization of the liver in Gastroenterology, where he remained until 2018 studying GPCRs and their signaling pathways in the liver and in liver disease. Richard Premont on the web Google Scholar LinkedIn Dr. GPCR Unlock the Full Dr.

. << Back to podcast list Strategic Partner(s) Jacob Lee and Jin Cho: Rebuilding the Software Layer Under Freezer inventories live in a senior postdoc's head. Genemode on the web Website Jacob Lee on LinkedIn Jacob Lee on Dr. GPCR Ecosystem Jin Choe on LinkedIn Jin Choe on Dr. GPCR Ecosystem Unlock the Full Dr. GPCR Learning Ecosystem ✔ Full Masterclass library ✔ Terry's Pharmacology Corner ✔ Advanced GPCR courses

. << Back to podcast list Strategic Partner(s) Model. Predict. Discover. with Dr. drug design, Jens discusses how his lab bridges simulation and experiment—and why understanding the limits AI and machine learning are opening new doors—but only if scientists know their tools’ limits. Outside academia, he advises companies through a consulting arm focused on ligand design strategy. Jens Carlsson on the web Carlsson Group Uppsala University LinkedIn Hit play now to hear how prediction

<< Back to podcast list Strategic Partner(s) Dr. Marta Filizola About Dr. Marta Filizola Dr. Marta Filizola on the web Icahn School of Medicine at Mount Sinai Filizola Lab Wikipedia Twitter Linkedin GPCR Learning Ecosystem ✔ Full Masterclass library ✔ Terry's Pharmacology Corner ✔ Advanced GPCR courses ✔ Scientific discussions → Become Premium Upcoming Live Expert Sessions ➚ 🔒Explore the Full Masterclass big difference. ★ Review on Apple Podcasts ★ Rate on Spotify ✉️ Send feedback to the team Thanks for listening