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  • Enzyme Inhibition Pharmacology: The Hidden Gatekeepers of GPCR Drug Discovery

    The transition from “magic” to mechanistic understanding, championed by pioneers like A.J. ethanol competes with methanol in cases of poisoning, you can gain insight into how simple enzyme logic translates

  • 📰 GPCR Weekly News, January 15 to 21, 2024

    receptor 141 expressed in myeloid cells functions as an inflammation suppressor Methods & Updates in GPCR Research Jude Children’s Research Hospital adds $13 million project to Research Collaboratives Program AIRSUPRA 20th World Congress of Basic and Clinical Pharmacology 2026 GPCR Jobs NEW Post-Doc position NEW Lead Researcher Senior Researcher in Structural Biology Post-Doctoral Fellow Postdoctoral Fellow Research Laboratory

  • 📰 GPCR Weekly News, April 17 to 23, 2023

    👋 Take a look at the latest and greatest in GPCR research. Methods & Updates in GPCR Research Solvent accessibility of a GPCR transmembrane domain probed by in-membrane July 2 - 7, 2023). 3rd Annual Meeting IRN I-GPCRNet (October 25 - 27, 2023) GPCR Jobs NEW Postdoctoral Researcher - Senior Scientist, Cell-Based Assay Development Post Doctoral Fellow Research associate in protein production Vice President, Oncology Clinical Research Explore Dr.

  • 📰 GPCR Weekly News, August 14 to 20, 2023

    glioblastoma through feed-forward activation of the SK1-S1P1 signaling axis Methods & Updates in GPCR Research latest science paper was published by the American College of Clinical Pharmacology Sosei and Cancer Research Channels, and Transport Proteins (March 24 - 29, 2024) GPCR Jobs NEW PhD Student Position NEW (Junior) Research Associate Protein Science Postdoctoral Fellow Research Laboratory Specialist Associate Postdoc Research Associate Director, Regulatory Affairs Research Scientist/Senior Scientist I - Molecular Pharmacology

  • 📰 GPCR Buzz: August 5-11, 2024 | Top Highlights from DrGPCR University!

    excitability of human induced pluripotent stem cell-derived nociceptive-like neurons Methods & Updates in GPCR Research Clinical Pharmacology GPCR Jobs Postdoc in GPCR mechanosensing   Postdoctoral Position Postdoctoral research position Senior or Lead Researcher   Senior Scientist, Cryo-Electron Microscopy   Postdoctoral Research

  • A robust and Efficient FRET-Based Assay for Cannabinoid Receptor Ligands Discovery.

    Cannabinoids as Anticancer Drugs: Current Status of Preclinical Research. Translational Potential of Allosteric Modulators Targeting the Cannabinoid CB1 Receptor. Nucleic Acids Research   2021 , 49 (12), e72–e72. https://doi.org/10.1093/nar/gkab237 . (20)      Degorce

  • 📰 GPCR Weekly News, July 3 to 9, 2023

    the Order of British Empire from King Charles III in recognition of his contributions to Biochemical Research Methods & Updates in GPCR Research Profiling of basal and ligand-dependent GPCR activities by means of Graeme Milligan was awarded the Order of British Empire by King Charles III for services to Biochemical Research Proteins (March 24 - 29, 2024) GPCR Jobs NEW Postdoctoral Fellow, Caron Lab NEW Clinical Trial Associate Research

  • Using Live-cell High-Content Screening to Characterize CB2 Ligands: Insights From 16 Synthetic Cannabinoids

    receptor type 2 (CB2R) has emerged as a compelling target across inflammation, immune modulation, and pain research By quantifying ligand–receptor interactions directly in intact cells, HCS allows researchers to observe Providing full tracer information ensures that researchers can recalculate or align affinity values across Quantitative affinity estimates are transparent and reproducible.   For researchers working in cannabinoid pharmacology, inflammation, or GPCR-mediated analgesia, these

  • Knowing When to Walk, Knowing When to Run: Lessons from the Bench

    Running Too Hard, Too Fast In research, there’s always more to do. Grants. Experiments.

  • 📰 GPCR Weekly News, January 23 to 29, 2023

    Keep up-to-date with the latest research and advancements in the field with our convenient, weekly news Methods & Updates in GPCR Research Development and Characterization of a Highly Selective Turn-On Fluorescent GPCR Jobs Scientist/Senior Scientist (Research Software Engineer) Senior Scientist – Native Mass Spectrometry Biochemistry) Speculative Applications (Mass Spectrometry) Speculative Applications (Chemistry) Post-Doctoral Research Assistant Research Fellow - School of Physics and Astronomy Postdoctoral Research Associate (Fixed Term

  • 📰 GPCR Weekly News, November 13 to 19, 2023

    of EBV-induced lymphomagenesis GPR56 signaling pathway network and its dynamics in the mesenchymal transition of glioblastoma Methods & Updates in GPCR Research Optogenetic Microwell Array Screening System: A High-Throughput Announces Settlement of INGREZZA Abbreviated New Drug Application (ANDA) Litigation PostEra Announces a Research Pharmacology 2026 GPCR Jobs NEW Sr Scientist in Obesity, Muscle, and Metabolism NEW Post-Doctoral Fellow NEW Research Associate I, Tissue Culture Post-Doc Research Associate Postdoctoral Fellow Research Scientist/Postdoctoral

  • 📰 GPCR Weekly News, February 6 to 12, 2023

    Keep up-to-date with the latest research and advancements in the field with our convenient, weekly news Methods & Updates in GPCR Research Engineered Human Antibody with Improved Endothelin Receptor Type A Bioinformatics/Data Science at Department of Drug Design and Pharmacology Scientist/Senior Scientist (Research Biochemistry) Speculative Applications (Mass Spectrometry) Speculative Applications (Chemistry) Post-Doctoral Research Assistant Research Fellow - School of Physics and Astronomy Postdoctoral Research Associate (Fixed Term

  • Dynamic GPCR activation revealed through time-resolved Cryo-EM

    complex with the β2-adrenergic receptor (β2AR) at brief sequential intervals following GTP addition, the research Twenty transition structures generated from overlapping particle subsets along this pathway provide a disrupting an ionic lock and allowing the α5 helix to start transitioning. This research not only deepens our understanding of a key biological process but also provides a valuable map for pharmaceutical researchers to design new therapies.

  • GPCR Buzz of the Week | Sep 23 - 29, 2024

    exceptional professors' ability to simplify the complexity of GPCR pharmacology and apply it to their research Europe July 12 - 17, 2026 | 20th World Congress of Basic and Clinical Pharmacology GPCR Jobs HIGHLIGHT Research Scientist, Computational Chemistry Postdoc in GPCR mechanosensing   Postdoctoral Position Postdoctoral research protein coupled receptor transcripts in human immune cells and platelets Methods & Updates in GPCR Research

  • 📰 GPCR Weekly News, August 7 to 13, 2023

    Half Year And Second Quarter Financial Results And Provides Corporate Update Sosei Heptares and Cancer Research GPCRs, Ion Channels, and Transport Proteins (March 24 - 29, 2024) GPCR Jobs NEW Postdoctoral Fellow NEW Research Laboratory Specialist Associate NEW Postdoc Research Associate Director, Regulatory Affairs Research

  • 📰 GPCR Weekly News, July 31 to August 6, 2023

    Devki D Sukhtankar and Pina M Cardarelli's research: Burixafor Hydrobromide (GPC-100) effects on hematopoietic dose-response for asbestos cancer risk implied by new inflammation-mutation model Methods & Updates in GPCR Research Modulator Program To Receive Additional Chf 2.7 Million From Indivior In Extended Substance Use Disorder Research Channels, and Transport Proteins (March 24 - 29, 2024) GPCR Jobs NEW Director, Regulatory Affairs NEW Research Robert Lefkowitz Lab Senior Research Specialist - Natural Sciences - Surgery Senior Scientist- Membrane

  • Navigating the Signaling Network: RTK and GPCR Crosstalk Uncovered

    The primary research question addressed in this study was: How do growth factors, specifically through The researchers focused on the phosphorylation of the G protein subunit Gαi at specific residues within In conclusion, this research elucidates the molecular mechanisms by which growth factors influence G

  • Jan Steyaert Named 2022 Jacob and Louise Gabbay Award Winner

    This award recognizes the combination of Steyaert’s fundamental research and his ability to apply the research to the development of therapeutic technologies. Steyaert bridged fundamental high-impact research in biomedical sciences with the mechanistic understanding

  • 📰 GPCR Weekly News, May 15 to 21, 2023

    Gαs slow conformational transition upon GTP binding and a novel Gαs regulator. Methods & Updates in GPCR Research Computational design of dynamic receptor-peptide signaling complexes July 2 - 7, 2023). 3rd Annual Meeting IRN I-GPCRNet (October 25 - 27, 2023) GPCR Jobs NEW Postdoctoral Research Associate NEW Lab Manager Vice President, Medical Affairs Associate Scientist - Technology Senior Research Scientist/Principal Scientist- Technology Tissue Culture Scientist/Tissue Culture Manager Postdoctoral Researcher

  • 📰 GPCR Weekly News, December 4 to 10, 2023

    structural validation of peptide-drug conjugate ligands of the kappa-opioid receptor GPCRs in Neuroscience Research injury by inhibiting inflammation and promoting cell self-renewal in mice Methods & Updates in GPCR Research World Congress of Basic and Clinical Pharmacology 2026 GPCR Jobs NEW Postdoctoral Fellow NEW Post-Doc Research Principal scientist – oncology biomarker expert Postdoctoral Fellow Scientific Assistant Scientist Lead Researcher

  • 📰 GPCR Weekly News, October 16 to 22, 2023

    Bianca Plouffe and their colleagues' research on 'β-arrestin-dependent and -independent endosomal GPCR signaling Ciliary localization of a light-activated neuronal GPCR shapes behavior Methods & Updates in GPCR Research Pharmaceuticals Senior Director, In vitro pharmacology - Crinetics Pharmaceuticals In vivo Antibody Discovery Research Scientist In Vitro Biologist/Molecular Pharmacologist Senior Vice President, Oncology Clinical Research

  • GPCR Weekly Whirlwind: Top Receptor Highlights from Sep 30 - Oct 6, 2024!

    simplify the intricacies of GPCR pharmacology for practical application in both academic and industrial research Europe July 12 - 17, 2026 | 20th World Congress of Basic and Clinical Pharmacology GPCR Jobs HIGHLIGHT Research Scientist, Computational Chemistry Postdoc in GPCR mechanosensing   Postdoctoral Position Postdoctoral research Group I Metabotropic Glutamate Receptors Dual regulation of IP3 receptors by IP3 and PIP2 controls the transition Receptors and Tumorigenesis: Implications for Diagnosis and Targeted Therapy Methods & Updates in GPCR Research

  • 📰 GPCR Weekly News, February 5 to 11, 2024

    GPCRs involved in metabolic diseases: pharmacotherapeutic development updates Methods & Updates in GPCR Research the G Protein-Coupled Receptor Rhodopsin Reviews, GPCRs, and more The dark sides of the GPCR tree - research Single-molecule Imaging Center NEW Scientific Assistant Postdoctoral Fellowship- Mechanistic Biology Research Scientist Post-Doc position Lead Researcher Join Dr.

  • 📰 GPCR Weekly News, April 3 to 9, 2023

    Methods & Updates in GPCR Research The Road to Quantitative Lipid Biochemistry in Living Cells. GPCR Events, Meetings, and Webinars NEW AACR 2023 - American Association for Cancer Research (April 14 (July 2 - 7, 2023). 3rd Annual Meeting IRN I-GPCRNet (October 25 - 27, 2023) GPCR Jobs Convergent Research - Senior Scientist, Cell-Based Assay Development Post Doctoral Fellow Research associate in protein production Vice President, Oncology Clinical Research PostDoctoral Associate PostDoctoral Position Team

  • What's Going On with GPCRs?! Find Out in This Week's Update! ⦿ Nov 4 - 10, 2024

    this week’s update, where you’ll find all the latest breakthroughs and exciting developments in GPCR research Scientist, Medicinal Chemistry PhD fellowship in GPCR mechanosensing Senior Scientist, GPCR Pharmacology Research in Oncology and Immunology GPR56: GPCR as a guardian against ferroptosis Methods & Updates in GPCR Research

  • The Chemistry of Confidence: Aha Moments That Shape Scientific Careers

    GPCR x Celtarys partnership , she’s extending those insights to researchers worldwide. 👉 Explore Celtarys

  • Unlock the Future of GPCR Science: Breakthroughs and Courses Await | Sep 2 - Sep 8, 2024

    Hello GPCR Enthusiasts, Dive into this week's exciting updates on cutting-edge GPCR research, new learning Protein-Coupled Receptors for New Therapeutic Options 📍  Boston, MA 📅 October 2 -3, 2024 Join top researchers Europe July 12 - 17, 2026 | 20th World Congress of Basic and Clinical Pharmacology GPCR Jobs HIGHLIGHT Research Scientist, Computational Chemistry Postdoc in GPCR mechanosensing   Postdoctoral Position Postdoctoral research interaction Early Events in β2AR Dimer Dynamics Mediated by Activation-Related Microswitches Nuclear translocation

  • 📰 GPCR Weekly News, February 13 to 19, 2023

    Get ready to stay up-to-date with the latest research, advancements, and news in the field. Bioinformatics/Data Science at Department of Drug Design and Pharmacology Scientist/Senior Scientist (Research Biochemistry) Speculative Applications (Mass Spectrometry) Speculative Applications (Chemistry) Post-Doctoral Research Assistant Research Fellow - School of Physics and Astronomy Postdoctoral Research Associate (Fixed Term

  • 📰 GPCR Weekly News, April 10 to 16, 2023

    Methods & Updates in GPCR Research Activity Map and Transition Pathways of G Protein-Coupled Receptor Highly Potent and Selective Inhibitor of GPR65, in Presentation at American Association for Cancer Research Targeted Oncology NEW Senior Scientist - Antibody Engineering NEW Scientist—Immuno-Oncology Convergent Research - Senior Scientist, Cell-Based Assay Development Post Doctoral Fellow Research associate in protein production Vice President, Oncology Clinical Research PostDoctoral Associate PostDoctoral Position Team

  • 📰 GPCR Weekly News, July 17 to July 23, 2023

    Antony Boucard's research on "Biased Signaling is Structurally Encoded As An Autoproteolysis Event in Methods & Updates in GPCR Research Fluorescent Ligands Enable Target Engagement Studies for the Intracellular Robert Lefkowitz Lab Senior Research Specialist - Natural Sciences - Surgery Senior Scientist- Membrane Technologies Computational Protein Design (GPCR) Postdoctoral Fellow, Caron Lab Clinical Trial Associate Research

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