Search Results

<< Back to podcast list Strategic Partner(s) Dr. Khaled Abdelrahman, Victoria Rasmussen and Madelyn Moore About Dr. Khaled Abdelrahman " Dr. Khaled Abdelrahman graduated in 2006 with a BSc in Pharmaceutical Sciences from Alexandria University (Egypt) followed by MSc in Pharmacology in the same university that was conferred in 2009. He joined the laboratory of Dr. William Cole at the University of Calgary in 2010 for his Ph.D. where he studied the molecular basis underlying altered cerebrovascular function and blood flow in type 2 diabetes. In 2015, He joined Dr. Stephen Ferguson’s laboratory in the Departments of Cellular & Molecular Medicine and Neuroscience at the University of Ottawa as a Postdoctoral Fellow to explore novel G protein-coupled receptor (GPCR) candidates that can be targeted pharmacologically to slow neurodegeneration. He has been also studying what aspects of GPCR signaling are regulated in a sex-selective manner and how this can influence drug discovery in the area of neurodegenerative diseases. He is also a Registered Pharmacist in Canada and held two of the most prestigious Clinician Postdoctoral Fellowships offered by Alberta Innovates and Canadian Institutes of Health Research. He received the Canadian Society of Pharmacology and Therapeutics Postdoctoral and Publication awards along with many Young Scientist Awards from the American Society for Pharmacology and Experimental Therapeutics. " Dr. Khaled Abdelrahman on the web Twitter PubMed Google Scholar Dr. GPCR About Victoria Rasmussen "Victoria Rasmussen is a graduate fellow in Dr. Thomas Sakmar’s laboratory at The Rockefeller University, where she study’s the signaling and degradation of G protein-coupled receptors. She completed her undergraduate education at Providence College, receiving a B.S. in Biology and a B.A. in psychology. During her time at Providence College, she received the Walsh Grant Fellowship to develop novel methods of synthesizing 2 -imidazoline scaffolds to be used as proteasome modulators in the laboratory of Travis Bethel. Victoria started her Ph.D. at the Tri-Institutional Ph.D. program in Chemical Biology, where she joined the lab of Thomas Sakmar at The Rockefeller University. She is currently working to understand the signaling and degradation of GPCRs in disease states to help test the feasibility of using protein-targeted degradation as a therapeutic strategy. " Victoria Rasmussen on the web Tri-Institutional PhD Program in Chemical Biology Rockefeller University LinkedIn Dr. GPCR About Madelyn Moore "Madelyn (Maddi) earned her B.S. in Biochemistry from the University of Minnesota-Duluth in 2020. In her time as an undergraduate, Maddi was a researcher in Dr. Amanda Klein's lab where she helped to investigate the role of various ATP-sensitive potassium channels in pain and opioid tolerance. From there, she went on to be a research technologist in Dr. Richard Vile's lab at Mayo Clinic where she aided the evaluation of tumor-specific oncolytic viruses. Maddi is currently a second year Ph.D. student in the Molecular Pharmacology and Therapeutics (MPaT) Graduate Program at the University of Minnesota. Advised by Dr. Lauren Slosky, she is working to understand the mechanism by which a new class of biased allosteric modulators for the neurotensin receptor 1 (NTSR1) act to attenuate the behavioral effects of methamphetamine." Madelyn Moore on the web MPaT PubMed LinkedIn Dr. GPCR Upcoming Live Expert Sessions ➚ 🔒Explore the Full Masterclass ➚ Unlock the Full Dr. GPCR Learning Ecosystem ✔ Full Masterclass library ✔ Terry's Pharmacology Corner ✔ Advanced GPCR courses ✔ Scientific discussions → Become Premium Recent Podcast Articles Asking Better Questions in Science: A Practical Guide for Emerging Researchers When the Islet Lit Up: Advancing GPCR Imaging in Native Tissue How Collaboration Sparked a GPCR Imaging Breakthrough in Chemical Biology Enjoying the Dr. GPCR Podcast? Leave a Review. Leave a quick review to help more scientists find the show—and help us keep improving every episode. It takes <60 seconds and makes a big difference. ★ Review on Apple Podcasts ★ Rate on Spotify ✉️ Send feedback to the team Thanks for listening to this podcast episode Follow us on your favorite Podcast Player << Previous Podcast Episode Next Podcast Episode >>

! Widget Didn’t Load Check your internet and refresh this page. If that doesn’t work, contact us. GPCR Retreat Program < Back to schedule Check In Date & Time Thursday, November 2nd / 4:00 PM ! Widget Didn’t Load Check your internet and refresh this page. If that doesn’t work, contact us. ! Widget Didn’t Load Check your internet and refresh this page. If that doesn’t work, contact us. Previous Event Next Event Great Lakes GPCR Retreat and Club des Récepteurs à Sept Domaines Transmembranaires du Québec ! Widget Didn’t Load Check your internet and refresh this page. If that doesn’t work, contact us.

Explore Martin Marro’s impact on GPCR drug discovery, assay innovation, and translational pharmacology bridging academia, pharma, and biotech. << Back to podcast list Strategic Partner(s) GPCR Assay Strategy, Bias, and Translational Drug Discovery This episode features Dr. Martin Marro, currently Executive Director and Head of Cell Pharmacology at Eli Lilly’s Obesity Research Group. Dr. Marro’s career spans big pharma and biotech, encompassing functional assay development, GPCR internalization research, and both small molecule and biologic drug discovery. He discusses his formative scientific experiences, critical decision points moving from academia into industry, and his role leading and shaping multidisciplinary teams for screening and innovative therapeutics targeting metabolic and cardiovascular diseases. The conversation explores the realities of using fluorescence-based assays, the challenge of translating in vitro pharmacology to in vivo models, lessons on bias agonism, and novel approaches in antibody discovery for GPCR targets. Dr. Marro’s path highlights the strategic and methodological pivots essential for driving projects into the clinic. For a deeper dive into modern GPCR research and tools, explore more episodes of the GPCR Podcast and discover Dr. GPCR Premium resources. Why This Matters? How advanced assay design is essential for translating cell-based GPCR signals to therapeutic outcomes. Why strategic flexibility in exploring non-canonical signaling pathways is critical for GPCR-targeted drug discovery. What learning from “failed” screens can reveal about receptor pharmacology and species selectivity. The moment when bias agonism and receptor trafficking concepts shifted industry standards for functional assays. How integrating antibody-based modalities has expanded options for hard-to-drug GPCR targets. Why persistent scientific questioning and collaborative networks accelerate GPCR innovation across disease areas. Who Should Listen? This episode is relevant to anyone navigating the complex landscape of GPCR research and translational pharmacology. Those facing disconnects between in vitro functional data and in vivo efficacy in GPCR programs. Researchers refining strategies for high-throughput screening or exploring biased signaling. Teams expanding into antibody or biologic modalities for challenging GPCR targets. Scientists seeking practical advice on career pivots between academia, pharma, and biotech. About Martin Marro Dr. Martin Marro leads the Cell Pharmacology group in the Diabetes, Obesity and Complications Therapeutic Area at Lilly's Seaport Innovation Center in Boston. His scientific training included a PhD at the International Center for Genetic Engineering and Biotechnology, followed by an industrial postdoctoral fellowship at GSK, where he entered the GPCR field and became proficient in aptamer selection and cell signaling assays. Dr. Marro’s career advanced through roles at Novartis and Tectonic Therapeutic, contributing to projects across key therapeutic areas—spanning metabolic, cardiovascular, and gastrointestinal diseases. With over two decades in drug discovery, he has established expertise in early phase functional assay development, small molecule and biologics research, and team leadership through high-profile programs. Awarded patents and a proven record in both target and pathway identification, his drive centers on integrating rigorous pharmacology with translational impact while cultivating innovation and scientific growth within his teams. Guest on The Web LinkedIn Upcoming Live Expert Sessions ➚ 🔒Explore the Full Masterclass ➚ Unlock the Full Dr. GPCR Learning Ecosystem ✔ Full Masterclass library ✔ Terry's Pharmacology Corner ✔ Advanced GPCR courses ✔ Scientific discussions → Become Premium Recent Podcast Articles Asking Better Questions in Science: A Practical Guide for Emerging Researchers When the Islet Lit Up: Advancing GPCR Imaging in Native Tissue How Collaboration Sparked a GPCR Imaging Breakthrough in Chemical Biology Enjoying the Dr. GPCR Podcast? Leave a Review. Leave a quick review to help more scientists find the show—and help us keep improving every episode. It takes <60 seconds and makes a big difference. ★ Review on Apple Podcasts ★ Rate on Spotify ✉️ Send feedback to the team Thanks for listening to this podcast episode Follow us on your favorite Podcast Player << Previous Podcast Episode Next Podcast Episode >>

Retreat 2023 About Program Registration Logo Contest Committee Sponsors GPCR Retreat Program < Back to schedule Structure-based discovery of functionally selective 5-HT1A receptor agonists Date & Time Saturday, November 4th / 9:05 AM Abstract Coming Soon About Peter Gmeiner "Prof. Dr. Peter Gmeiner received his Ph.D. from the University of Munich. He was a postdoc at the University of California in Berkeley, USA. He subsequently returned to Munich as a research associate at the Institute of Pharmaceutical Chemistry. Upon receiving his Dr. Habilitus, he was appointed at the University of Bonn as a Professor of Pharmaceutical Chemistry declining an offer for a professorship at the University of Heidelberg, at the same time. Peter has been chaired Full Professor of Pharmaceutical / Medicinal Chemistry at the Friedrich-Alexander University Erlangen-Nürnberg and declined an offer for the Chair for Pharmaceutical Chemistry at the University of Münster. Peter Gmeiner has been spokesman of the Research Training Group "Medicinal Chemistry of Selective GPCR Ligands" (GRK 1910). " Peter Gmeiner on the web Friedrich Alexander University Erlangen-Nürnberg Pubmed Google Scholar LinkedIn Dr. GPCR Previous Event Next Event Great Lakes GPCR Retreat and Club des Récepteurs à Sept Domaines Transmembranaires du Québec Great Lakes GPCR Retreat and Club des Récepteurs à Sept Domaines Transmembranaires du Québec 22nd GPCR Retreat Sponsored by

Retreat 2023 About Program Registration Logo Contest Committee Sponsors GPCR Retreat Program < Back to schedule Breakfast 1 Date & Time Friday, November 3rd / 7:30 AM Previous Event Next Event Great Lakes GPCR Retreat and Club des Récepteurs à Sept Domaines Transmembranaires du Québec Great Lakes GPCR Retreat and Club des Récepteurs à Sept Domaines Transmembranaires du Québec 22nd GPCR Retreat Sponsored by

<< Back to podcast list Strategic Partner(s) Dr. Neil Grimsey About Dr. Neil Grimsey " During my postdoctoral studies at USCD, I discovered a novel GPCR-dependent atypical kinase activation mechanism that drives vascular edema and inflammation. These studies shaped my future goals as an Assistant Professor in the College of Pharmacy at the University of Georgia Athens. My group studies the spatiotemporal dynamics of atypical inflammation and the control of disease progression. We have developed an array of fluorescent biosensors to map kinase activity in living cells and are exploring innovative techniques to delineate the molecular dynamics of atypical p38 and suppress kinase activation. To further define the role of atypical p38 signaling responses we are studying how atypical p38 controls the onset and pathogenesis of acute lung injury, retinal vasculopathies, and infections. " Dr. Neil Grimsey on the web LinkedIn University of Georgia Google Scholar X (Twitter) Dr. GPCR Upcoming Live Expert Sessions ➚ 🔒Explore the Full Masterclass ➚ Unlock the Full Dr. GPCR Learning Ecosystem ✔ Full Masterclass library ✔ Terry's Pharmacology Corner ✔ Advanced GPCR courses ✔ Scientific discussions → Become Premium Recent Podcast Articles Asking Better Questions in Science: A Practical Guide for Emerging Researchers When the Islet Lit Up: Advancing GPCR Imaging in Native Tissue How Collaboration Sparked a GPCR Imaging Breakthrough in Chemical Biology Enjoying the Dr. GPCR Podcast? Leave a Review. Leave a quick review to help more scientists find the show—and help us keep improving every episode. It takes <60 seconds and makes a big difference. ★ Review on Apple Podcasts ★ Rate on Spotify ✉️ Send feedback to the team Thanks for listening to this podcast episode Follow us on your favorite Podcast Player << Previous Podcast Episode Next Podcast Episode >>

<< Back to podcast list Strategic Partner(s) Dr. Christel Menet About Dr. Christel Menet "I did my Ph.D. in Manchester UK with Prof Jonathan Clayden in organic chemistry. I then started my career at Evotec before moving to Domain Therapeutics (called Faust pharmaceutical at the time). After 2 years, I joined Galapagos where I spent almost 11 years and became head of medicinal chemistry. 6 years ago I decided to take on a new challenge by taking the position of CSO at Confo Therapeutics . I was the 6th employee and today we are more than 60 :) I have fun every day, and I love working with GPCRs. they are such great targets." Dr. Christel Menet on the web Hyphen Projects GPCRS Drug Discovery Confo Therapeutics LinkedIn Dr. GPCR Ecosystem Upcoming Live Expert Sessions ➚ 🔒Explore the Full Masterclass ➚ Unlock the Full Dr. GPCR Learning Ecosystem ✔ Full Masterclass library ✔ Terry's Pharmacology Corner ✔ Advanced GPCR courses ✔ Scientific discussions → Become Premium Recent Podcast Articles Asking Better Questions in Science: A Practical Guide for Emerging Researchers When the Islet Lit Up: Advancing GPCR Imaging in Native Tissue How Collaboration Sparked a GPCR Imaging Breakthrough in Chemical Biology Enjoying the Dr. GPCR Podcast? Leave a Review. Leave a quick review to help more scientists find the show—and help us keep improving every episode. It takes <60 seconds and makes a big difference. ★ Review on Apple Podcasts ★ Rate on Spotify ✉️ Send feedback to the team Thanks for listening to this podcast episode Follow us on your favorite Podcast Player << Previous Podcast Episode Next Podcast Episode >>

<< Back to podcast list Strategic Partner(s) Dr. Fiona Marshall About this episode Fiona Marshall got fascinated with GPCRs after attending a lecture on how the beta-adrenergic receptor in the heart is activated by adrenaline, during her undergraduate studies at Bath University. She then pursued her Ph.D. in neuroscience at Cambridge University. An expert in GPCR biology, Fiona published the first description of the cloning and structural requirements of the GABAB receptor. One of her career path-defining moments came when she visited Dr. Chris Tate and Dr. Richard Henderson at the Laboratory of Molecular Biology in Cambridge, UK. As a co-founder of Heptares Therapeutics , now called Sosei Heptares , a GPCR-focused drug discovery and development biotechnology company, Fiona and her team made considerable breakthroughs in the field of GPCR stabilization and structure-based drug design. Today, Dr. Marshall is the VP Head of Neuroscience Discovery and Head of Discovery UK, Global Head of Neuroscience discovery research leading teams in West Point, Boston, and London at MSD. Join me and learn more about her fascinating career trajectory. Dr. Fiona Marshall on the web LinkedIn Twitter Google Scholar MSD UK Dr. GPCR Ecosystem Upcoming Live Expert Sessions ➚ 🔒Explore the Full Masterclass ➚ Unlock the Full Dr. GPCR Learning Ecosystem ✔ Full Masterclass library ✔ Terry's Pharmacology Corner ✔ Advanced GPCR courses ✔ Scientific discussions → Become Premium Recent Podcast Articles Asking Better Questions in Science: A Practical Guide for Emerging Researchers When the Islet Lit Up: Advancing GPCR Imaging in Native Tissue How Collaboration Sparked a GPCR Imaging Breakthrough in Chemical Biology Enjoying the Dr. GPCR Podcast? Leave a Review. Leave a quick review to help more scientists find the show—and help us keep improving every episode. It takes <60 seconds and makes a big difference. ★ Review on Apple Podcasts ★ Rate on Spotify ✉️ Send feedback to the team Thanks for listening to this podcast episode Follow us on your favorite Podcast Player << Previous Podcast Episode Next Podcast Episode >>

Retreat 2023 About Program Registration Logo Contest Committee Sponsors GPCR Retreat Program < Back to schedule Illuminating Functional Selectivity and Allosterism at GPCRs. Date & Time Saturday, November 4th / 11:30 AM Abstract Coming Soon About Stéphane Laporte "Dr. Stéphane Laporte is a Professor of Medicine, and the Director of Research of the Division of Endocrinology and Metabolism at McGill University. He is also an Associate Leader of the Experimental Therapeutics and Metabolism Program and the Director of the Molecular Imaging Platform at the Research Institute of the McGill University Health Centre (RI-MUHC). He is a member of the Executive Committee of the Réseau québécois de recherche sur les médicaments. He has received many awards, including a Canada Research Chair, FRSQ scholarships and the CDA/CSEM/Merck Frosst Young Investigator award. His expertise is in molecular pharmacology and his research program focuses on the molecular and cellular mechanisms regulating G protein-coupled receptor (GPCR) responses, a class of receptors involved in many, if not all, physiological responses, with the ultimate goal of improving drug action. He has developed innovative methods for in-cellulo measurement of protein-protein interactions, receptor trafficking and signalling, useful for drug discovery programs. His research program also studies the allosteric, biased signalling regulation of GPCR and has contributed to the validation of small molecules that block myometrial contraction in pre-term birth. He has contributed to the generation of many intellectual property agreements and patents, and published his findings in high-impact journals. The Canadian Institutes for Health Research and March of Dimes currently support his research." Stéphane Laporte on the web Laporte Lab McGill University LinkedIn Dr. GPCR Previous Event Next Event Great Lakes GPCR Retreat and Club des Récepteurs à Sept Domaines Transmembranaires du Québec Great Lakes GPCR Retreat and Club des Récepteurs à Sept Domaines Transmembranaires du Québec 22nd GPCR Retreat Sponsored by

<< Back to podcast list Strategic Partner(s) Dr. Nyla Naim, Dr. Michael Lemieux & Dr. Jason Nasse About Dr. Nyla Naim Nyla is a Senior Scientist on the Scientific Support Team at Addgene . She received her Ph.D. at the University of Pittsburgh and continued her postdoctoral research at the University of Vermont studying cellular signaling, biosensors, and optogenetics. Nyla supports biomedical research by connecting researchers with resources and promoting reproducible science. Dr. Nyla Naim on the web LinkedIn Dr. GPCR Ecosystem About Dr. Michael Lemieux ''My name is Michael (Mike) Lemieux and I am a Connecticut native. I completed my Ph.D. in molecular and cell biology at UConn and then joined Addgene as a Quality Control Scientist in 2015. Since then I transitioned into a Scientific Support role to leverage my passion for helping people! Beyond my interest in science, I am a strong advocate for graduate education reform and I love to write.'' Dr. Michael Lemieux on the web Addgene Blog Dr. GPCR Ecosystem About Dr. Jason Nasse Dr. Jason Nasse is a senior scientist at Addgene specializing in the use of AAV viral vectors. He obtained his Ph.D. in Neuroscience from Ohio State University focusing on synaptic plasticity and adrenergic receptor modulation of both pre-and postsynaptic properties. By taking a very non-traditional path to obtain a Ph.D. Dr. Nasse has had the opportunity to experience how science is performed across different sectors and around the country. Prior to his role at Addgene, Jason held roles in academia, big pharma, and non-profit research organizations. Dr. Jason Nasse on the web LinkedIn Dr. GPCR Ecosystem Upcoming Live Expert Sessions ➚ 🔒Explore the Full Masterclass ➚ Unlock the Full Dr. GPCR Learning Ecosystem ✔ Full Masterclass library ✔ Terry's Pharmacology Corner ✔ Advanced GPCR courses ✔ Scientific discussions → Become Premium Recent Podcast Articles Asking Better Questions in Science: A Practical Guide for Emerging Researchers When the Islet Lit Up: Advancing GPCR Imaging in Native Tissue How Collaboration Sparked a GPCR Imaging Breakthrough in Chemical Biology Enjoying the Dr. GPCR Podcast? Leave a Review. Leave a quick review to help more scientists find the show—and help us keep improving every episode. It takes <60 seconds and makes a big difference. ★ Review on Apple Podcasts ★ Rate on Spotify ✉️ Send feedback to the team Thanks for listening to this podcast episode Follow us on your favorite Podcast Player << Previous Podcast Episode Next Podcast Episode >>

Retreat 2023 About Program Registration Logo Contest Committee Sponsors GPCR Retreat Program < Back to schedule Welcome Reception and Poster Session 1 Date & Time Thursday, November 2nd / 5:30 PM Previous Event Next Event Great Lakes GPCR Retreat and Club des Récepteurs à Sept Domaines Transmembranaires du Québec Great Lakes GPCR Retreat and Club des Récepteurs à Sept Domaines Transmembranaires du Québec 22nd GPCR Retreat Sponsored by

<< Back to podcast list Strategic Partner(s) Dr. John Streicher About this episode Our guest in this episode of the Dr.GPCR podcast is Dr. John Streicher from the department of pharmacology at the University of Arizona. John started grad school in 1999 and spent some time figuring out what he was interested in. It turns out that it was signal transduction, and he worked on the signaling cascades involved in heart failure. His encounter and interest in signaling in the context of GPCRs during his postdoctoral training in Dr. Laura Bohn’s lab at Scripps Research Institute in Florida. Today, John and his team focus on understanding how signal transduction cascades downstream of the opioid receptors work, including the unique organization of chaperone protein Hsp90 modulation of opioid signaling in the brain versus the spinal cord. Dr. John Streicher on the web University of Arizona Department of Pharmacology Google Scholar Pubmed LinkedIn Dr. GPCR Ecosystem Upcoming Live Expert Sessions ➚ 🔒Explore the Full Masterclass ➚ Unlock the Full Dr. GPCR Learning Ecosystem ✔ Full Masterclass library ✔ Terry's Pharmacology Corner ✔ Advanced GPCR courses ✔ Scientific discussions → Become Premium Recent Podcast Articles Asking Better Questions in Science: A Practical Guide for Emerging Researchers When the Islet Lit Up: Advancing GPCR Imaging in Native Tissue How Collaboration Sparked a GPCR Imaging Breakthrough in Chemical Biology Enjoying the Dr. GPCR Podcast? Leave a Review. Leave a quick review to help more scientists find the show—and help us keep improving every episode. It takes <60 seconds and makes a big difference. ★ Review on Apple Podcasts ★ Rate on Spotify ✉️ Send feedback to the team Thanks for listening to this podcast episode Follow us on your favorite Podcast Player << Previous Podcast Episode Next Podcast Episode >>

Submit your abstract for the Adhesion GPCR Workshop 2024. Share your research, connect with experts, and be part of the leading GPCR scientific community. ABSTRACT SUBMISSION Adhesion GPCR workshop 2024 CINVESTAV, Mexico City, Mexico October 23-25 Submit your Abstract Here Abstracts configuration 1. Abstract category (oral presentations) 2. Title: Capitalize each word, 20 words max, Bold 3. Authors’ names in full: Last name, First name 4. Institutions 5. Abstract body 6. Funding source Oral presentations Extended deadline: August 1st Speaker name indicated in bold and underlined Indicate abstract category on top left corner (up to 2 categories max) Abstract categories Signaling Trafficking Metabolism Structure and Bioinformatics Health and Disease Immunology Nervous system Model Organism Phylogenetics and Evolution Aging Basic and Clinical Pharmacology Proteomic and Transcriptomics Biosensors and Molecular Tools Biomarkers Poster presentations Deadline: August 1 The presenter's name is indicated in bold and underlined Poster size Poster width: 90 cm max Poster height: 140 cm max Register for the Adhesion GPCR 2024 [ Registration extended until September 15th ] Learn more about the Adhesion GPCR workshop 2024 Up About the event Learn more about the Adhesion GPCR Workshop 2024 and its preliminary program. Up About the venue Discover Cinvestav, the host venue for the upcoming workshop. Up Traveling Tips Find essential tips about Mexico City, including transportation options and local insights. Up Logo Contest Enter our logo contest for a chance to have your design represent the upcoming event.

Join the forefront of GPCR research at the Dr. GPCR Summit! Embracing innovation and technology, we connect global scientific communities. Experience talks spanning time zones, with options for live or pre-recorded presentations. Uncover groundbreaking insights in GPCR science together. Learn more. Meet Dr. GPCR Summit Partners - Click to Explore - Dr. GPCR Summit 2021 Welcome to the official page of the Dr. GPCR Virtual Summit 2021! << Live talk schedule >> << Pre-recorded talk list >> The program is complete! Don't miss a chance to listen to 25+ scientific talks, which will only be available for those who registered during the Summit. Get your All-Access ticket before they're gone by visiting Eventbrite today! Got your All-Access ticket already? Special shout out to our partners! Check your inbox this week, you'll be able to invite a friend or colleague to join the Summit for Free! Proceeds from the ticket sales will be used to provide the best three trainee talks with fantastic prizes, including a personalized autographed copy of Dr. Lefkowitz's biography. Present a pre-recorded talk and get free access to the entire Summit! Hurry, the deadline to submit your talk is Friday, September 10th, 2021, at midnight EST. If you're facing financial difficulties or are a trainee who would like to attend but can't submit a pre-recorded talk, reaches out to us now! The live talks will be held on Zoom, and everyone who registered will be able to ask their questions to the speakers all week on Microsoft Teams! You'll also be able to meet our partners on Microsoft Teams. Make sure you have a profile picture set for both Zoom and Microsoft Teams! Everyone is welcome to present their work (students, postdocs, PI's, biotech, pharma companies)! There are no posters! All pre-recorded talks will be available during the summit for free with registration. All live talks will have a $5 attendance fee/ talk You can get full access to all the talks for $100 For Speakers Step 1: Let us know that you'd like to present your work by filling out this short form here Step 2: Prepare your video abstract and your presentation (pre-recorded or live)* Step 3: Click here to send us your pre-recorded presentation or click here*** to submit the information to your live presentation before August 5th, 2021. ***All live talks are now scheduled Please provide us with your pre-recorded presentation by September 10th, 2021 *Note: Scroll down to find resources to help you prepare your video presentation, and don't hesitate to get in touch if you need help. Contact us at Hello@DrGPCR.com Some housekeeping items first We strongly suggest you carefully consider what type of information you share in your presentation. We will do our best to keep the Summit a closed event, but Dr.GPCR is not responsible for any loss of intellectual property. How will I access the talks during the Summit? You will receive an email from Eventbrite containing the relevant information before the summit. Be sure to register. How can I sponsor the 2021 Summit? Please visit our Sponsor Page to learn more about sponsorship opportunities to sponsor the Summit and the DrGPCR Ecosystem. For more information, please email us at Hello@DrGPCR.com In what form can I submit my abstract? Abstract submission can be in the form of classical text abstract or in the form of a short (max. 3 minutes) video. This is an excellent opportunity to be as creative as you want to be. We recommend writing a 200-300 word abstract, giving you enough information to provide a great video abstract in under 3 minutes. How will I present my talk? You can pre-record your talk. We recommend submitting pre-recorded talks. What does this mean? You send us the video of your full-length talk, and we will take care of the rest. Alternatively, you can provide us with the embed code to make your presentation available during the Summit. Pros: You can polish your recording to your satisfaction. Anyone can watch it from anywhere, even multiple times. Imagine binge-watching your favorite talk over and over whenever you want to during the Summit. Cons: It may take more time to record an excellent presentation, but nothing is impossible! Click here to submit your pre-recorded presentation. Can I present a live talk or event? How? In case you'd like to present a talk live, we'll help with it. Pros: It may take less time to prepare for the presentation Cons: You may make mistakes since it's a live event, and if you decide to keep your talk live only, participants can watch it only once. *Tip Become a DR. GPCR Member by creating your own personalized page. Read more about becoming a member here . If you need help preparing your pre-recorded video and video abstract check out these resources: How to record your talk in PowerPoint 365 How to record your talk using a previous PowerPoint version How to record your talk using Keynote on a Mac Do you have any questions? Email us at Hello@DrGPCR.com << Live talk schedule >> << Pre-recorded talk list >> Meet Dr. GPCR Summit Partners - Click to Explore - Tags Dr. GPCR Summit Dr. GPCR Summit 2021 Dr. GPCR Summit 2021 Pre-Recorded Talks Dr. GPCR Summit 2021 Live Talks

Thank you for joining the Dr. GPCR Ecosystem! Stay tuned for updates, exclusive content, and exciting opportunities in the world of GPCR research. Thank you, Donor Name We are so grateful for your generous donation of $0. Your donation number is #1000. You’ll receive a confirmation email soon.

<< Back to podcast list Strategic Partner(s) Dr. Graciela Pineyro About this episode Dr. Graciela Pineyro’s love for GPCR pharmacology started in Uruguay where she first worked on the serotonin receptors. This interest in research and pharmacology took Graciela to Canada where she stayed ever since she arrived for her Ph.D. work. Graciela has done extensive work on the molecular pharmacology of opioid receptors, exploring their signaling, trafficking, and their ability to activate different signaling pathways and signaling bias. Today, Graciela and her team’s efforts are directed towards the characterization of the pharmacological properties of cannabinoids in conjunction with terpenes for pain relief. Dr. Graciela Pineyro on the web Dr. Graciela Pineyro on LinkedIn Dr. Graciela Pineyro - University of Montreal Dr. Graciela Pineyro - CHU Ste-Justine Research Centre Pineyro Lab Publications on Google Scholar Pineyro Lab on Pubmed Dr. GPCR Ecosystem Upcoming Live Expert Sessions ➚ 🔒Explore the Full Masterclass ➚ Unlock the Full Dr. GPCR Learning Ecosystem ✔ Full Masterclass library ✔ Terry's Pharmacology Corner ✔ Advanced GPCR courses ✔ Scientific discussions → Become Premium Recent Podcast Articles Asking Better Questions in Science: A Practical Guide for Emerging Researchers When the Islet Lit Up: Advancing GPCR Imaging in Native Tissue How Collaboration Sparked a GPCR Imaging Breakthrough in Chemical Biology Enjoying the Dr. GPCR Podcast? Leave a Review. Leave a quick review to help more scientists find the show—and help us keep improving every episode. It takes <60 seconds and makes a big difference. ★ Review on Apple Podcasts ★ Rate on Spotify ✉️ Send feedback to the team Thanks for listening to this podcast episode Follow us on your favorite Podcast Player << Previous Podcast Episode Next Podcast Episode >>

<< Back to podcast list Strategic Partner(s) Steve McCloskey About Steve McCloskey Steve McCloskey is an Alumni from the first class of Nanoengineering at the University of California, San Diego. Steve’s work is focused on emerging technologies applied to Science, Technology, Engineering, and Mathematics (STEM). During his time at UC San Diego Steve worked directly with the founding Chair of the Nanoengineering Department, Ken Vecchio helping set the foundation for the Nanoengineering Materials Research Center and developing thermodynamic processing methods for Iron-based Superelastic alloys. After graduating from UCSD he founded Nanome Inc to build Virtual Reality solutions for Scientists and Engineers working at the nanoscale, specifically protein engineering and small molecule drug development. Steve McCloskey on the web Website LinkedIn Twitter ResearchGate Medium Orchid Dr. GPCR Ecosystem Upcoming Live Expert Sessions ➚ 🔒Explore the Full Masterclass ➚ Unlock the Full Dr. GPCR Learning Ecosystem ✔ Full Masterclass library ✔ Terry's Pharmacology Corner ✔ Advanced GPCR courses ✔ Scientific discussions → Become Premium Recent Podcast Articles Asking Better Questions in Science: A Practical Guide for Emerging Researchers When the Islet Lit Up: Advancing GPCR Imaging in Native Tissue How Collaboration Sparked a GPCR Imaging Breakthrough in Chemical Biology Enjoying the Dr. GPCR Podcast? Leave a Review. Leave a quick review to help more scientists find the show—and help us keep improving every episode. It takes <60 seconds and makes a big difference. ★ Review on Apple Podcasts ★ Rate on Spotify ✉️ Send feedback to the team Thanks for listening to this podcast episode Follow us on your favorite Podcast Player << Previous Podcast Episode Next Podcast Episode >>

Retreat 2023 About Program Registration Logo Contest Committee Sponsors GPCR Retreat Program < Back to schedule Trainee Symposium I Date & Time Thursday, November 2nd / 1:45 PM - 2:45 PM Title: Virion Display to Discover a Novel Ligand of the Orphan GPCR GPRC5B and its Role in Obesity About Eric Johansen "I will be a 6th year Ph.D student in the chemical biology interface program at Johns Hopkins University. My project is investigating a new protein ligand for a GPCR and its potential role in obesity. My interests in research are primarily directed towards methods that study GPCRs and GPCR signaling, as well as drug discovery and design." Eric Johansen on the web Johns Hopkins University Dr. GPCR Title: Modeling Cardiac Fibrosis in a Dish: Combining hIPSC-Derived Fibroblasts and FRET Biosensors to Unravel GPCR-Mediated Cardiac Fibrosis Activation in Dilated Cardiomyopathy About Grace Mazarura "I am a graduate student in the Hébert Lab. In my current research project I use iPSC-derived cardiac fibroblasts to examine cellular signaling in the fibrotic response, a key driver of dilated cardiomyopathy." Grace Mazarura on the web McGill University Dr. GPCR Title: Characterization of Novel Opioid-Neurotensin Bifunctional Ligands Designed to Target Pain Management About Émile Breault "Emile Breault is undertaking his master's degree in pharmacology at the university of Sherbrooke under the supervision of Prof. Sarret. He recently received his BSc in pharmacology from the University of Sherbrooke in 2023. During his graduate studies, Emile is interested in characterizing novel G protein-coupled receptors (GPCRs) ligands for the treatment of chronic pain but also in deciphering cellular signaling pathways associated with the physiological effects observed in vivo of such GPCRs." Émile Breault on the web Google Scholar ResearchGate Dr. GPCR Title: Synapse-Associated Protein 102 and Post-Synaptic Density 95 Differentially Shape Dopamine D1 Receptor Signaling About Bassam Albraidy "My thesis focus on studying the interaction of dopamine D1 receptors scaffolding proteins synapse-associated protein 102 and post-synaptic density 95, and the impact of these complexes in D1R-mediated signaling and trafficking mechanisms." Bassam Albraidy on the web X (Twitter) LinkedIn Dr. GPCR Previous Event Next Event Great Lakes GPCR Retreat and Club des Récepteurs à Sept Domaines Transmembranaires du Québec Great Lakes GPCR Retreat and Club des Récepteurs à Sept Domaines Transmembranaires du Québec 22nd GPCR Retreat Sponsored by

Discover how finance and science intersect in this Dr. GPCR Podcast episode with Joe St. Germain and Chuck DeWeese, as they share what it takes to build mission-driven startups and research organizations. << Back to podcast list Strategic Partner(s) Finance is Science too: How Numbers Keep the Lights On with Chuck DeWeese & Joe St. Germain In Episode Dr. Yamina Berchiche welcomes Chuck DeWeese and Joe St. Germain of Company Launch Partners for an inspiring discussion on the intersection of accounting, entrepreneurship, and nonprofit mission building . With the Dr. GPCR ecosystem officially becoming a nonprofit, this episode offers valuable insight into the financial backbone required to scale scientific and community-driven initiatives. The Launch Pad: Company Launch Partners Joe St. Germain, founder of Company Launch Partners, shares how he transitioned from corporate finance to creating a service firm dedicated to startups and nonprofits . A self-declared problem-solver, Joe describes how working with early-stage companies reignited his passion for helping others build impactful ventures. Chuck DeWeese, controller at CLP, joined the mission after pivoting from a sales career into accounting, where he found his professional calling in " making the numbers make sense ." "There’s something really sick with accounting people... that accounting high when everything reconciles." – Chuck DeWeese The Nonprofit Spark: Partnering with Dr. GPCR The episode dives into how Joe and Chuck began collaborating with the Dr. GPCR ecosystem. Yamina reached out to Joe with accounting questions during his vacation—an email that sparked a partnership. Chuck stepped in to help structure the nonprofit’s financial framework , showcasing how specialized knowledge and timing can catalyze long-term collaborations. “You always email me when I’m on vacation.” – Joe St. Germain (laughing) Accounting Highs & Scientific Parallels Yamina draws a parallel between reconciling complex financial data and a scientist getting a long-awaited result. Both Chuck and Joe agree: accounting is like solving puzzles. It's about structure, order, and breakthrough moments , not unlike the life of a researcher. “Finance grows the beans, but you don’t get to that point until you count them.” – Chuck DeWeese Jumping Off the Cliff: The Entrepreneur’s Leap Joe shares the risks of launching a business while supporting a family, emphasizing the mental resilience and self-care needed. He compares entrepreneurship to a scientist’s journey: uncertainty, trial-and-error, and the necessity of mentorship. "I’m a startup working with startups. That support system made the leap manageable." – Joe St. Germain Networking: Relationship Over Transaction Both guests stress that business is built on relationships , not transactions. Joe often helps people with problems unrelated to accounting, simply to build trust. Chuck adds that networking is about planting seeds and being patient. “We assess and sometimes say: ‘You’re not quite at our level yet. Let’s help you set up and come back when you’re ready.’” – Chuck DeWeese Accounting for Grants: Buckets, Structure & Strategy The discussion covers the unique complexities of grant accounting in nonprofits. Unlike startups, nonprofits must adhere to strict allocation rules. Chuck explains that every dollar needs a bucket and purpose. "Accounting counts the beans with 100% accuracy. Finance grows the beans, but you don’t get to finance without accounting first." – Chuck DeWeese Culture Fit: Who Gets to Join the Team? When building their team, Joe and Chuck prioritize character over experience . They look for organized, upbeat, can-do individuals—many of whom are working mothers. A standout story is Kendra, a team member with no prior accounting experience who quickly became a key contributor. "Hire for character, train for skill. That’s how we grow." – Joe St. Germain The Joy of Building with Purpose Joe’s personal mission— to make a positive impact on people’s lives —drives their client selection. They avoid companies that don’t align with their values, like the vaping industry. Instead, they seek out startups and nonprofits working toward social impact and innovation . “We’ve only turned down one client for ethical reasons. We want to make the world better.” – Joe St. Germain The Science of Finance: A Shared Language Throughout the episode, Yamina and her guests underscore that finance and science share more than most people think —both require rigor, discipline, and a process-oriented mindset. This realization forms a deep connection between accountants and scientists alike. “Accounting is a science too. You build systems, track data, and interpret outcomes.” – Chuck DeWeese Final Reflections: Growing Together Yamina closes with the story behind the podcast’s creation—how a moment at a Starbucks in Target led her to launch a platform that now empowers GPCR scientists worldwide. It’s about finding the right people, solving hard problems, and creating something bigger than yourself . "I come alive when I do this. The podcast is about connecting people through science and story." – Yamina Berchiche Key Takeaway Whether you're launching a startup, building a nonprofit, or running a research lab, success comes down to relationships, integrity, and learning the systems that power sustainability . And yes, finance is a science too. About Company Launch Partners Company Launch Partners is a fractional finance and accounting service focused on early stage companies. Simply put, we partner with companies to help them launch. The company has been working with startup companies since 2017, serves 25 clients and has assisted over a 100 companies as they start their journey. Company Launch Partners on the web Company Launch Partners Upcoming Live Expert Sessions ➚ 🔒Explore the Full Masterclass ➚ Unlock the Full Dr. GPCR Learning Ecosystem ✔ Full Masterclass library ✔ Terry's Pharmacology Corner ✔ Advanced GPCR courses ✔ Scientific discussions → Become Premium Recent Podcast Articles Asking Better Questions in Science: A Practical Guide for Emerging Researchers When the Islet Lit Up: Advancing GPCR Imaging in Native Tissue How Collaboration Sparked a GPCR Imaging Breakthrough in Chemical Biology Enjoying the Dr. GPCR Podcast? Leave a Review. Leave a quick review to help more scientists find the show—and help us keep improving every episode. It takes <60 seconds and makes a big difference. ★ Review on Apple Podcasts ★ Rate on Spotify ✉️ Send feedback to the team Thanks for listening to this podcast episode Follow us on your favorite Podcast Player << Previous Podcast Episode Next Podcast Episode >>

Retreat 2023 About Program Registration Logo Contest Committee Sponsors GPCR Retreat Program < Back to schedule Removing the GPCR-mediated brake on exocytosis enhances insulin action, promotes adipocyte browning, and protects against diet-induced obesity Date & Time Friday, November 3rd / 2:45 PM Abstract Coming Soon Authors and Affiliations Ryan P. Ceddia 1, *, Zack Zurawski 2,3,*, Analisa Thompson Gray 2, Feyisayo Adegboye 2, Ainsley McDonald-Boyer 3, Fubiao Shi 1, Dianxin Liu 1, Jose Maldonado 5, Jiesi Feng 4, Yulong Li 4, Simon Alford 5, Julio E. Ayala 5, Owen P. McGuinness 5, Sheila Collins 1,5, Heidi E. Hamm 2 1 Department of Medicine, Division of Cardiovascular Medicine, Vanderbilt University Medical Center, Nashville, TN 37232, USA 2 Department of Pharmacology, Vanderbilt University, Nashville, TN 37232, USA 3, 5 Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, TN 37232, USA 4 Peking University, China 5 Department of Anatomy and Cell Biology, University of Illinois at Chicago, Chicago, IL 60612, USA. About Heidi Hamm "Heidi E. Hamm, Ph.D. is the Aileen M. Lange and Annie Mary Lyle Chair in Cardiovascular Research, and Professor of Pharmacology, Ophthalmology and Visual Sciences, and Orthopedics at Vanderbilt University. This is one of the top Pharmacology departments in the country, judged by reputation, citation analysis, and NIH funding. She oversaw an increase of the size of the Department, as well as a quintupling of its NIH funding, in her 14 years as Chair. The Department’s strengths lie in GPCR signal transduction and neuroscience, and she has expanded it in the areas of drug discovery and structural biology of membrane proteins. Her research focuses on the structure and function of GTP binding proteins and the molecular mechanisms of signal transduction. Her laboratory has been involved in studying G protein coupled signal transduction for many years and has made key discoveries in G protein structure and mechanisms of activation by GPCRs and activation of effectors. Current areas of interest include Protease Activated Receptor signaling in the cardiovascular system and regulation of vesicular exocytosis mediated by Gi/o-coupled receptors by G subunit binding to SNAREs. Dr. Hamm obtained her Ph.D. in 1980 from the Department of Zoology at the University of Texas-Austin and did postdoctoral training in the University of Wisconsin-Madison from 1980-1983. Her initial research centered around circadian clocks and melatonin synthesis in the avian retina; her postdoctoral work investigated the role of the G protein transducin in visual transduction using blocking monoclonal antibodies. She held faculty appointments at the University of Illinois at Chicago School of Medicine and Northwestern University before moving to Vanderbilt in 2000. She has received numerous awards, including the Glaxo Cardiovascular Discovery Award, the Distinguished Investigator Award from the National Alliance for Research in Schizophrenia and Depression, the Faculty of the Year award from the University of Illinois College of Medicine, and the Stanley Cohen Award “For Research Bringing Diverse Disciplines, such as Chemistry or Physics, to Solving Biology’s Most Important Fundamental Problems” from Vanderbilt University in 2003. She gave the Fritz Lipmann Lecture at ASBMB in 2001. " Heidi Hamm on the web The Hamm Lab Vanderbilt School of Medicine Pubmed Google Scholar LinkedIn Twitter Dr. GPCR Previous Event Next Event Great Lakes GPCR Retreat and Club des Récepteurs à Sept Domaines Transmembranaires du Québec Great Lakes GPCR Retreat and Club des Récepteurs à Sept Domaines Transmembranaires du Québec 22nd GPCR Retreat Sponsored by

<< Back to podcast list Strategic Partner(s) Dr. Antonella Di Pizio About this episode In this episode of the Dr. GPCR podcast , we meet with Dr. Antonella Di Pizio, an independent research group leader at the Leibniz Institute for Food Systems Biology at the Technical University of Munich. Antonella trained as a medicinal chemist in Italy, followed by a Ph.D. in computational medicinal chemistry, during which she developed a taste for structural biology. Antonella then moved to Israel, where she first started working on bitter taste GPCRs in Dr. Masha Niv's lab . Today, Antonella has expanded her research to olfactory GPCRs and trace amine receptors. Join us to learn more about chemosensory GPCRs and how computational pharmacology can help better understand their function. Dr. Antonella Di Pizio on the web Leibniz-Institute for Food Systems Biology at the Technical University of Munich Google Scholar PubMed LinkedIn Dr. GPCR Ecosystem Upcoming Live Expert Sessions ➚ 🔒Explore the Full Masterclass ➚ Unlock the Full Dr. GPCR Learning Ecosystem ✔ Full Masterclass library ✔ Terry's Pharmacology Corner ✔ Advanced GPCR courses ✔ Scientific discussions → Become Premium Recent Podcast Articles Asking Better Questions in Science: A Practical Guide for Emerging Researchers When the Islet Lit Up: Advancing GPCR Imaging in Native Tissue How Collaboration Sparked a GPCR Imaging Breakthrough in Chemical Biology Enjoying the Dr. GPCR Podcast? Leave a Review. Leave a quick review to help more scientists find the show—and help us keep improving every episode. It takes <60 seconds and makes a big difference. ★ Review on Apple Podcasts ★ Rate on Spotify ✉️ Send feedback to the team Thanks for listening to this podcast episode Follow us on your favorite Podcast Player << Previous Podcast Episode Next Podcast Episode >>

<< Back to podcast list Strategic Partner(s) Nicole Perry-Hauser About Nicole (Nicki) Perry-Hauser I am a postdoctoral research fellow endeavoring to build a productive, independent scientific research career in adhesion G protein-coupled receptor (aGPCR) biology. My long-term research interests involve resolving signaling pathways downstream of aGPCRs and establishing how/if these receptors’ adhesive properties influence signaling events, and in turn, whether signaling impacts synapse formation and neuronal wiring. Mutations in aGPCRs have been linked to various neuropsychiatric phenotypes, and my work will provide a basis for understanding aGPCR biology in the nervous system. Nicole (Nicki) Perry-Hauser on the web LinkedIn Research Gate Pubmed Dr. GPCR Ecosystem Upcoming Live Expert Sessions ➚ 🔒Explore the Full Masterclass ➚ Unlock the Full Dr. GPCR Learning Ecosystem ✔ Full Masterclass library ✔ Terry's Pharmacology Corner ✔ Advanced GPCR courses ✔ Scientific discussions → Become Premium Recent Podcast Articles Asking Better Questions in Science: A Practical Guide for Emerging Researchers When the Islet Lit Up: Advancing GPCR Imaging in Native Tissue How Collaboration Sparked a GPCR Imaging Breakthrough in Chemical Biology Enjoying the Dr. GPCR Podcast? Leave a Review. Leave a quick review to help more scientists find the show—and help us keep improving every episode. It takes <60 seconds and makes a big difference. ★ Review on Apple Podcasts ★ Rate on Spotify ✉️ Send feedback to the team Thanks for listening to this podcast episode Follow us on your favorite Podcast Player << Previous Podcast Episode Next Podcast Episode >>

<< Back to podcast list Strategic Partner(s) Dr. Kenneth A. Jacobson About Dr. Kenneth A. Jacobson Kenneth A. Jacobson received his BA in Liberal Arts from Reed College in 1976 and his Ph.D. in Chemistry from the University of California, San Diego in 1981. He completed postdoctoral training at the Weizmann Institute. In 1983, he joined the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) at the National Institutes of Health, in Bethesda, MD. He is currently the Senior Investigator and Chief of the Molecular Recognition Section, Laboratory of Bioorganic Chemistry. He adapts interdisciplinary approaches (synthesis, modeling, pharmacology) to study G protein-coupled receptors (GPCRs) and purinergic signaling and now has four compounds in clinical trials. He has published more than 800 scientific publications, with an H-index of 115. His numerous awards include: 2008 Sato Award; 2009 Medicinal Chemistry Hall of Fame (American Chemical Soc.); 2014 Goodman and Gilman Award; 2017 Tu Youyou Award; 2017 Smissman Award; 2023 Hershberg Award. Dr. Kenneth A. Jacobson on the web NIDDK Web of Science Google Scholar LinkedIn Twitter Dr. GPCR Upcoming Live Expert Sessions ➚ 🔒Explore the Full Masterclass ➚ Unlock the Full Dr. GPCR Learning Ecosystem ✔ Full Masterclass library ✔ Terry's Pharmacology Corner ✔ Advanced GPCR courses ✔ Scientific discussions → Become Premium Recent Podcast Articles Asking Better Questions in Science: A Practical Guide for Emerging Researchers When the Islet Lit Up: Advancing GPCR Imaging in Native Tissue How Collaboration Sparked a GPCR Imaging Breakthrough in Chemical Biology Enjoying the Dr. GPCR Podcast? Leave a Review. Leave a quick review to help more scientists find the show—and help us keep improving every episode. It takes <60 seconds and makes a big difference. ★ Review on Apple Podcasts ★ Rate on Spotify ✉️ Send feedback to the team Thanks for listening to this podcast episode Follow us on your favorite Podcast Player << Previous Podcast Episode Next Podcast Episode >>

Retreat 2023 About Program Registration Logo Contest Committee Sponsors GPCR Retreat Program < Back to schedule Biochemical Mechanisms Underlying Location Bias in GPCR Signaling Date & Time Saturday, November 4th / 8:40 AM Abstract Coming Soon About Sudarshan Rajagopal "Dr. Sudarshan Rajagopal is a physician-scientist and is currently an Associate Professor of Medicine and Biochemistry at Duke University School of Medicine. He obtained his B.S. in Chemistry from The University of Chicago in 1998 and subsequently enrolled in the Medical Scientist Training Program at The University of Chicago. During his doctoral work in the lab of Prof. Keith Moffat, he studied the structural mechanisms of bacterial photoreceptors using time-resolved Laue crystallography. He was awarded his PhD in 2004 and his MD in 2006. He then joined the Internal Medicine Residency training program at Duke University Medical Center. During his Cardiology fellowship, he trained in the lab of Dr. Robert J. Lefkowitz, where his research focused on biased agonism, with the development of approaches to quantify ligand bias and the identification of ACKR3 as an endogenously beta-arrestin-biased receptor. After completing his training, he joined the faculty at Duke, with a focus on the mechanisms underlying biased agonism at GPCRs and its contribution inflammation and cardiovascular disease. His group and others have shown that many of these ligands act as biased agonists for the same receptor. His lab is also interested in identifying novel signal transduction mechanisms of GPCRs, such as the formation of complexes between G proteins and beta-arrestins. His clinical focus is on pulmonary arterial hypertension, a disease of the pulmonary arterioles that causes right heart failure, and he serves as co-director of the Duke Pulmonary Vascular Disease Center." Sudarshan Rajagopal on the web The Rajagopal Lab Google Scholar Pubmed LinkedIn Dr. GPCR Previous Event Next Event Great Lakes GPCR Retreat and Club des Récepteurs à Sept Domaines Transmembranaires du Québec Great Lakes GPCR Retreat and Club des Récepteurs à Sept Domaines Transmembranaires du Québec 22nd GPCR Retreat Sponsored by

<< Back to podcast list Strategic Partner(s) Developing new tools to uncover GPCR signaling patterns with Remi Janicot About Remi Janicot I was born in Paris (France) and grew up in Europe until I was 18. After graduating high school, I moved to America to pursue my passion for basketball while continuing high level studies. I played collegiate basketball and earned my bachelor’s at Ursinus College, a small school around Philadelphia where I graduated from in 2018. After that, I worked at Johns Hopkins in Baltimore as a research assistant investigating mechanisms and treatments for pediatric epilepsy. With my background in neuroscience, the lab of Dr. Mikel Garcia-Marcos seemed like a good fit as GPCRs are integral to the functioning of the nervous system (and much more). My particular projects revolve around developing new tools to study GPCR activity in ways that were not previously possible. This research has led to a first-author Cell article on the development of a new biosensor platform called ONE-GO biosensors. Overall, the lab works on diverse models and diseases, and has developed a wide array of tools to dissect GPCR/G protein signaling which I would be happy to discuss. Remi Janicot on the web Chobanian & Avedisian School of Medicine Upcoming Live Expert Sessions ➚ 🔒Explore the Full Masterclass ➚ Unlock the Full Dr. GPCR Learning Ecosystem ✔ Full Masterclass library ✔ Terry's Pharmacology Corner ✔ Advanced GPCR courses ✔ Scientific discussions → Become Premium Recent Podcast Articles Asking Better Questions in Science: A Practical Guide for Emerging Researchers When the Islet Lit Up: Advancing GPCR Imaging in Native Tissue How Collaboration Sparked a GPCR Imaging Breakthrough in Chemical Biology Enjoying the Dr. GPCR Podcast? Leave a Review. Leave a quick review to help more scientists find the show—and help us keep improving every episode. It takes <60 seconds and makes a big difference. ★ Review on Apple Podcasts ★ Rate on Spotify ✉️ Send feedback to the team Thanks for listening to this podcast episode Follow us on your favorite Podcast Player << Previous Podcast Episode Next Podcast Episode >>

! Widget Didn’t Load Check your internet and refresh this page. If that doesn’t work, contact us. GPCR Retreat Program < Back to schedule Lunch 1 Date & Time Friday, November 3rd / 12:10 PM ! Widget Didn’t Load Check your internet and refresh this page. If that doesn’t work, contact us. ! Widget Didn’t Load Check your internet and refresh this page. If that doesn’t work, contact us. Previous Event Next Event Great Lakes GPCR Retreat and Club des Récepteurs à Sept Domaines Transmembranaires du Québec ! Widget Didn’t Load Check your internet and refresh this page. If that doesn’t work, contact us.

Stay informed and accountable with our comprehensive Content and Conduct Policy. Join Dr. GPCR Ecosystem and promote a positive online community. Content and Conduct Policy Dr. GPCR, Corp, LLC (“Dr. GPCR”) provides its Service to you through our websites referred to as Dr. GPCR, Ecosystem.DrGPCR.com, DrGPCR.com. We rely heavily on users to report content that may violate our policies. After we are notified of a potential policy violation, we may review the content and take action, including restricting access to the content, removing the content, and limiting or terminating a user’s access to Ecosystem.DrGPCR.com products. Note that we may make exceptions to these policies based on artistic, educational, or documentary considerations or when there are other substantial benefits to the public from not taking action. We respect the freedom of speech. Please note that Ecosystem.DrGPCR.com is specializes in GPCR and related subjects. We occasionally modify these policies, so please check back here for updates. Beyond the guidelines listed below, please note that several products and features may have additional policies and terms; check the provided links for those specific requirements. Responsibility for Your Content You are solely responsible for Your Content, and once published, it may not always be withdrawn. You assume all risks associated with Your Content, including anyone's reliance on its quality, accuracy, or reliability, or any disclosure by you of information in Your Content that makes you personally identifiable. You represent that you own or have the necessary permissions to use and authorize your Content as described herein. You may not imply that Your Content is in any way sponsored or endorsed by Ecosystem.DrGPCR.com. You may expose yourself to liability if, for example, Your Content contains material that is false, intentionally misleading, or defamatory; violates any third-party right, including any copyright, trademark, patent, trade secret, moral right, privacy right, right of publicity, or any other intellectual property or proprietary right; contains unlawful material, including illegal hate speech or pornography; exploits or otherwise harms minors, or violates or advocates the violation of any law or regulation. Our Right to Use Your Content You also give Ecosystem.DrGPCR.com (Website) a perpetual, irrevocable, worldwide, royalty-free, and non-exclusive license to reproduce, adapt, modify, translate, publish, publicly perform, publicly display, distribute, store and create derivative works of the basic listing information about your entity that you provide to your Ecosystem.DrGPCR.com Account (such as the entity name, location, phone number, list of interest, business category, hours, services, product descriptions, text, videos, contents, and website) We may use Your Content in several different ways, including publicly displaying it, reformatting it, incorporating it into advertisements and other works, creating derivative works from it, promoting it, distributing it, and allowing others to do the same in connection with their websites and media platforms ("Other Media"). As such, you at this moment irrevocably grant us worldwide, perpetual, non-exclusive, royalty-free, assignable, sub-licensable, transferable rights to use Your Content for any purpose. Please note that you irrevocably grant the users of the Site and any Other Media the right to access Your Content in connection with their use of the Site and any Other Media. Finally, you irrevocably waive and cause to be waived against Ecosystem.DrGPCR.com and its users any claims and assertions of moral rights or attribution with respect to Your Content. By "use" we mean use, copy, publicly perform and display, reproduce, distribute, modify, translate, remove, analyze, commercialize, and prepare derivative works of Your Content. Ownership Between you and Ecosystem.DrGPCR.com, you own Your Content. We own the Ecosystem.DrGPCR.com Content, including but not limited to visual interfaces, interactive features, graphics, design, compilation, including, but not limited to, our compilation of User Content and other Site Content, computer code, products, software, aggregate user review ratings, and all other elements and components of the Site excluding Your Content, User Content and Third Party Content. We also own the copyrights, trademarks, service marks, trade names, and other intellectual and proprietary rights throughout the world ("IP Rights") associated with the Ecosystem.DrGPCR.com Content and the Site, which are protected by copyright, trade dress, patent, trademark laws and all other applicable intellectual and proprietary rights and laws. As such, you may not modify, reproduce, distribute, create derivative works or adaptations of, publicly display or in any way exploit any of the Ecosystem.DrGPCR.com Content in whole or in part except as expressly authorized by us. Except as expressly and unambiguously provided herein, we do not grant you any express or implied rights, and we retain all rights in and to the Site and the Ecosystem.DrGPCR.com Content. Advertising Ecosystem.DrGPCR.com and its licensees may publicly display advertisements and other information adjacent to or included with Your Content. You are not entitled to any compensation for such advertisements. The manner, mode, and extent of such advertising are subject to change without specific notice to you. Content We make some of the Ecosystem.DrGPCR.com Site Content available to third parties. You may access and use these content in order to display on your personal computer, website, or blog ("Your Site"), provided that (i) your use of the Feeds is for personal, non-commercial purposes only, (ii) your display of the Feed Content links back to the relevant pages on Ecosystem.DrGPCR.com Website's websites, and attributes Ecosystem.DrGPCR.com as the source of the Content, (iii) your use or display of the Content does not suggest that Ecosystem.DrGPCR.com promotes or endorses any third party causes, ideas, websites, products or services, including Your Site, (iv) you do not redistribute the Content, and (v) your use of the Content does not overburden Ecosystem.DrGPCR.com Website’s systems. Ecosystem.DrGPCR.com reserves all rights in the Content and may terminate the Content at any time. Other User Content (including any that may have been created by users employed or contracted by the Ecosystem.DrGPCR.com Website) does not necessarily reflect the opinion of Ecosystem.DrGPCR.com. We reserve the right to remove, screen, edit, or reinstate User Content at our sole discretion, for any reason or no reason, and without notice to you, from time to time. For example, we may remove a review if we believe it violates our Content Guidelines. We have no obligation to retain or provide you with copies of Your Content, nor do we guarantee any confidentiality with respect to Your Content. Illegal Activities Do not use our Services to engage in illegal activities or promote dangerous and illegal acts. Malicious and Deceptive Practices Do not transmit viruses, malware, or any other malicious or destructive code. Do not distribute content that harms or interferes with the operation of the networks, servers, or other infrastructure of Ecosystem.DrGPCR.com or others. Do not use our Services for phishing scams. Hate Speech Our products are platforms for free expression. But we don't support content that promotes or condones violence against individuals or groups based on race or ethnic origin, religion, disability, gender, age, nationality, veteran status, or sexual orientation/gender identity, or whose primary purpose is inciting hatred on the basis of these core characteristics. This can be a delicate balancing act, but if the primary purpose is to attack a protected group, the content crosses the line. Personal and Confidential Information Do not distribute other people’s personal and confidential information, such as credit card numbers, confidential national ID numbers, or account passwords, without their permission. Do not post or distribute images or videos of minors without the necessary consent from their legal representatives. Account Hijacking Do not access another user’s account without their permission. Child Exploitation Do not upload or share content that exploits or abuses children. This includes all child sexual abuse imagery (even cartoon images or videos) and all content that presents children in a sexual manner. We will remove such content and take appropriate action, which may include disabling accounts and reporting to the National Center for Missing & Exploited Children (NCMEC) and law enforcement. Note that this policy may additionally apply to any content uploaded or transmitted through Photos or Videos. If you find any content that you think exploits children in this manner, do not share or comment on such content, even if your intent is to bring it to Ecosystem.DrGPCR.com's attention. Instead, flag the content. If you find content elsewhere on the internet, please contact NCMEC directly. Spam Do not spam, including by sending unwanted promotional or commercial content, or mass solicitations. Do not aggressively follow people or aggressively message people that you do not know. Ranking Manipulation Do not manipulate rankings or relevancy using techniques such as repetitive or misleading keywords or metadata. Sexually Explicit Material Do not distribute sexually explicit or pornographic material. Do not drive traffic to commercial pornography sites. Note that your profile photo cannot include mature or offensive content. For example, do not use a photo that is a close-up of a person’s buttocks or cleavage. Harassment, Bullying, and Threats Do not engage in harassing, bullying, or threatening behavior, and do not incite others to engage in these activities. Anyone using our Services to single someone out for malicious abuse, to threaten someone with serious harm, to sexualize a person in an unwanted way, or to harass in other ways may have the offending content removed or be permanently banned from using the Services. In emergency situations, we may escalate imminent threats of serious harm to law enforcement. Keep in mind that online harassment is also illegal in many places and can have serious offline consequences for both the harasser and the victim. Violence Do not distribute depictions of graphic or gratuitous violence. Impersonation Do not use our Services to mislead or confuse users by pretending to be someone else or pretending to represent an organization you do not represent. Regulated Goods and Services Your content cannot promote regulated goods and services, including but not limited to alcohol, gambling, unapproved supplements, tobacco, fireworks, or weapons. If we receive a complaint that such content violates applicable laws and regulations, we will remove and delete the offending content or account. Contests and Promotions Ecosystem.DrGPCR.com allows contests, sweepstakes, and other promotions ("Promotions") to the extent permitted by law, subject to the following policy requirements and legal terms outlined below. 1. Generating spam or encouraging individuals to engage in spam or abuse is strictly prohibited. Please note that the definition of spam on Ecosystem.DrGPCR.com may develop and change over time, and that Ecosystem.DrGPCR.com reserves the right to determine what qualifies as spam. In order to play a part in helping us fight spam and abuse, we have the following specific requirements for Promotions: 1a. The official rules for your Promotion must include a clear statement that anyone found to have created multiple accounts in order to increase their chances of winning, or anyone who posts entries in excess of an entry limit you have set, will be disqualified from the Promotion. You must set an entry limit for your promotion below a level that is likely to encourage spam. 1b. If you ask participants to use tags and/or hashtags in their Promotion entries, they must be relevant to the kind of content users are posting. For example, do not ask for photos of sunsets with #spaghetti. 2. Promotions should not be used to try to circumvent any applicable terms or policies. 3. Do not run Promotions that offer potential rewards in exchange for sharing content, following a user, mentioning a user (other than the contest creator, sponsor, or an affiliate of the contest creator or sponsor), having other users enter the promotion, or voting in polls. Also, avoid running promotions that encourage users to post unoriginal or repetitive content. 4. Please note that doing a public search (via hashtag or otherwise) may not show every entry or every participant in your Promotion. Accordingly, you should not rely solely on the search feature to view or find all entries or participants in your Promotion. 5. Please note that some Promotion entries may be filtered, hidden, or removed from Ecosystem.DrGPCR.com for spam or quality reasons, or any of our other applicable policies or terms of service. Use of Multiple Accounts Do not create or use multiple accounts to evade our policies or bypass blocks or otherwise subvert restrictions placed on your account. For example, if you’ve been blocked by another user or suspended for abuse, don’t create a replacement account that engages in similar activity. Please read carefully our Legal Policies and Disclaimers to understand how Dr. GPCR conducts business Affiliate Policy Content and Conduct Policy Content Guidance Privacy Policy Terms and Conditions Trademark Policy

Founded in 2020, Dr. GPCR unites researchers, industry, and partners to accelerate GPCR science and drug discovery—through connection, education, and real‑world collaboration. About Dr. GPCR Ecosystem We unite the GPCR community to advance drug discovery. We bring the GPCR community together to fuel GPCR drug discovery—one receptor at a time. Our goal is to deepen our understanding of GPCR function and accelerate the development of better therapies together. Founded in 2020, Dr. GPCR was created to break down barriers across academia, biotech, pharma, and CROs—so knowledge, tools, and talent can flow where they’re needed most. Contact Us Our Mission Advance GPCR science and drug discovery by connecting people, data, and opportunities across the global GPCR ecosystem. Our Vision A world where GPCR insights translate quickly into real‑world therapies through an open, trusted, and collaborative community. What We Do (in Three Verbs) Connect — Researchers, founders, students, and industry partners meet, learn, and collaborate. Educate — Courses, talks, and curated content that turn expertise into execution. Accelerate — Intros, resources, and visibility that move projects and careers forward. Who Should Join To join the community, you should be actively related to the GPCR field , including: Academic researchers (PI, postdoc, student) Industry scientists and R&D leaders Biotech and pharma founders/operators CRO/technology providers serving GPCR programs Clinicians and translational teams Investors and BD professionals focused on GPCRs Eligibility: We verify GPCR relevance during onboarding to preserve focus and quality. Partner With Us Build visibility, trust, and feedback directly from your target audience. Partner perks: Direct interaction with researchers, founders, and decision‑makers Access to all member perks for your entire team Product & service listings in ecosystem directories Speaking, demo, and content opportunities Input into community programming and field priorities CTA: Contact us to partner Our Values Scientific Rigor — Evidence first; hype last Openness with Intent — Share to accelerate; respect boundaries Diversity & Inclusion — More perspectives → better science Member‑First — We build what the community needs Execution — Ideas become results through consistent cadence Meet The Team Founder & Director Yamina Berchiche Get in touch Co-Founder Attila Foris Get in touch Board Member Anne M. Quinn Get in touch Board Member JoAnn Trejo Get in touch Board Member Maria Waldhoer Get in touch Chief Matchmaker Mark Schmeizl Get in touch

Dr. Michelle Halls reveals how organized GPCR signaling drives assay innovation and new therapeutic insights. << Back to podcast list Strategic Partner(s) Leadership, Impact, and GPCR Signaling with Dr. Michelle Halls In this episode Dr. Michelle Halls shares how dissecting the spatial organization of GPCR signaling opens new doors in drug discovery. From early discoveries in cyclic AMP signaling to uncovering ultrasensitive receptor responses at femtomolar ligand concentrations, her work highlights why receptor localization and protein complex assembly matter for therapeutic targeting. This conversation is especially valuable for scientists developing functional assays, fluorescence-based tools, and high-throughput GPCR screens. Inside This Episode How ultrasensitive GPCR signaling emerges from pre-assembled receptor–effector complexes at the plasma membrane. Why receptor localization and scaffolding dramatically shift functional readouts in disease models. What early cyclic AMP assays revealed about spatial signaling long before high-content technologies existed. The moment when femtomolar ligand concentrations uncovered unexpected receptor sensitivity. How an integrated training and lab structure at Monash Institute of Pharmaceutical Sciences fosters innovation in functional assay development and GPCR research. Why It Might Hit Home If you’ve ever: Faced unexpected assay behavior at ultra-low ligand concentrations, Balanced innovation with robust validation under real experimental constraints, Tried to map signaling heterogeneity in disease-relevant models, Built assays that need to work in real biology—not just on paper, …this episode will resonate. About the Guest Michelle Halls is an Associate Professor at Monash University and Deputy Theme Leader of Drug Discovery Biology at Monash Institute of Pharmaceutical Sciences. She leads the Spatial Organisation of Signalling Laboratory, where her team investigates how GPCRs orchestrate localized signaling events, how these mechanisms are hijacked in disease, and how they can be leveraged for therapeutic innovation. Michelle earned her PhD in Molecular Pharmacology at Monash University, then trained in single-cell biology as an NHMRC CJ Martin Fellow at University of Cambridge. She established her lab in 2011, and today she is a Viertel Senior Medical Research Fellow. Her recognitions include the 2024 ASCEPT Achievement Award, the 2023 BPS Geoffrey Burnstock Prize, and the 2019 Faculty Future Research Leader Award. More about Michelle Halls Monash Institute of Pharmaceutical Sciences Bluesky LinkedIn Articles about this Podcast Episode How GPCR Spatial Signaling Sparked a Scientific Journey From Pipettes to Platforms: The Evolution of GPCR Research How GPCR Collaboration Built an Innovation Engine 🎓 Want more like this? Get behind-the-scenes conversations, advanced assay development strategies, and practical GPCR tools inside Dr. GPCR Premium . Join a global GPCR community of scientists and biotech leaders. 👉 Join now Upcoming Live Expert Sessions ➚ 🔒Explore the Full Masterclass ➚ Unlock the Full Dr. GPCR Learning Ecosystem ✔ Full Masterclass library ✔ Terry's Pharmacology Corner ✔ Advanced GPCR courses ✔ Scientific discussions → Become Premium Recent Podcast Articles Asking Better Questions in Science: A Practical Guide for Emerging Researchers When the Islet Lit Up: Advancing GPCR Imaging in Native Tissue How Collaboration Sparked a GPCR Imaging Breakthrough in Chemical Biology Enjoying the Dr. GPCR Podcast? Leave a Review. Leave a quick review to help more scientists find the show—and help us keep improving every episode. It takes <60 seconds and makes a big difference. ★ Review on Apple Podcasts ★ Rate on Spotify ✉️ Send feedback to the team Thanks for listening to this podcast episode Follow us on your favorite Podcast Player << Previous Podcast Episode Next Podcast Episode >>

Discover the rules and guidelines that govern your participation in the Dr. GPCR Ecosystem. Explore our Terms and Conditions page now! Terms and Conditions Dr. GPCR, Corp (“Dr. GPCR”) provides its Service to you through our websites referred to as Dr. GPCR, Ecosystem.DrGPCR.com, DrGPCR.com. 1. ACCEPTANCE OF TERMS: This is a legal document, outlining the Agreement on Terms of Service (the “ATS”) for our website, Ecosystem.DrGPCR.com (the “Website”). By using our Website, you agree to fully comply with and be bound by the following ATS each time you use our Website. Please review the following terms carefully. Dr. GPCR, Corp (“Dr. GPCR”) provides its Service (as defined below) to you through this website, subject to this ATS. By accepting this ATS or by accessing or using the Service or Website, you acknowledge that you have read, understood, and agree to be bound by this ATS. If you are entering into this ATS on behalf of a company, business, or other legal entity, you represent that you have the authority to bind such entity and its affiliates to this ATS. If you do not have such authority, or if you do not agree with this ATS, you must not accept this ATS and may not use the Service. Dr. GPCR, Corp (“Dr. GPCR”) may change this ATS from time to time without prior notice. You can review the most current version of this ATS at any time in our Website. The revised terms and conditions will become effective upon posting and if you use the Service after that date, your use will constitute acceptance of the revised terms and conditions. If any change to this ATS is not acceptable to you, stop accessing and using the Service. This agreement contains warranty disclaimers and other provisions that limit our liability to you. Please read these terms and conditions carefully and in their entirety, as using, accessing, and/or browsing our Website constitutes acceptance of these terms and conditions. If you do not agree to be bound to each and every term and condition set forth herein, please exit our website immediately and do not use access and/or access it further. 2. SERVICES: Ecosystem.DrGPCR.com is an online platform that provides to (i) individuals and businesses such as scientists, students, biotech companies, and others with access to advertise, to promote, and market their services and products related to the biotech industry; and to (ii) individuals and businesses who are seeking to buy, to sell, to invest, to rent, or those who wish to find services to assist or to represent her/his/them in consummating any of these transactions (the “Services”). Individuals and businesses under this section are defined as “Customer” or “Customers”. Such Services includes also access to the Website, and to all software (including the Software, as defined below), data, reports, text, images, sounds, video, and content made available through the Website or any additional instrument of communication (collectively referred to as the “Content”). Any new features implemented for the amelioration of the Services are also subject to this ATS. 3. GENERAL CONDITIONS. a. Access and Use of the Services: Customer(s) is/are required to register with Ecosystem.DrGPCR.com and to open an account in order to access and use certain features of the Services, which may include your own creation and posting your own page within the scope of the Services. If Customer(s) choose(s) to register for the Services, he/she/they agree(s) to provide and maintain true, accurate, current information about himself/herself/themselves. For use of data and other information please refer to our Privacy Policy. b. Membership Fees / Payment: By registering and opening an account with Ecosystem.DrGPCR.com on the Website in order to carry out the activity within the scope of the Services, the Customer(s) agree(s) to be bound by the terms of this ATS and to provide Ecosystem.DrGPCR.com with all the information necessary to process the monthly or yearly membership fee payment in order to access the Services within the Website. Service(s)’ payment for the membership fee shall be made in full, via Wix Payment. Paypal, Stripe, or Bank Transfer method of payment. The membership fee shall be on a monthly or yearly basis, with an option from the Customer for automatic renewal. 4. REFUND POLICY: Any payment made from the Customer to Ecosystem.DrGPCR.com to membership fees shall not be refunded under any circumstances. 5. ADDITIONAL TERMS: Subject to the terms and conditions of this ATS, the Customer shall access and use the Services only for lawful purposes. All rights, title, and interest in and to the Services and its components will remain with and belong exclusively to Ecosystem.DrGPCR.com. Customer shall not (a) sublicense, resell, rent, lease, transfer, assign, or otherwise dispose of, exploit or make the Services available to any third party; (b) use the Services in any unlawful manner or in any manner that interferes with or disrupts the integrity or performance of the Services or its components, or (c) modify the Services, or otherwise attempt to gain unauthorized access to the Services or its related systems or networks. Customer shall comply with any codes of conduct, policies, or other notices Ecosystem.DrGPCR.com provides to Customer or publishes in connection with the Services. Any software that may be made available by Ecosystem.DrGPCR.com in connection with the Services (“Software”) contains proprietary and confidential information that is protected by applicable intellectual property and other laws. Any rights not expressly granted herein are reserved and, except as expressly provided herein, no license or right to use any trademark of Ecosystem.DrGPCR.com is granted to you in connection with the Services. This ATS contains provisions that govern how claims between Customer and Ecosystem.DrGPCR.com are resolved. It also contains an arbitration clause, which will, with limited exception, require the Customer to submit claims it has against Ecosystem.DrGPCR.com to binding and final arbitration. 6. CUSTOMER INFORMATION: Customer is solely responsible for all data, information, and other materials that it upload, post, advertises, promotes, markets, delivers, provides, or otherwise transmits or stores, in connection with or relating to the Services (“Customer Information”). The customer is responsible to maintain the confidentiality of its login information and for all activities that occur under its login or account access information. Ecosystem.DrGPCR.com reserves the right to access the Customer’s account in order to respond to its requests for technical support. By posting Customer Information on or through the Services, Customer hereby does and shall grant Ecosystem.DrGPCR.com a worldwide, non-exclusive, perpetual, irrevocable, royalty-free, fully paid, sub-licensable, and transferable license to use, modify, reproduce, distribute, display, publish and perform Customer Information in connection with the Services. Ecosystem.DrGPCR.com has the right, but not the obligation, to monitor the Services, Content, or Customer Information. The customer further agrees that Ecosystem.DrGPCR.com may remove or disable any Content at any time for any or for no reason at all. Customer understands that the operation of the Services, including Customer Information, may involve (a) transmissions over various networks; (b) changes to conform and adapt to technical requirements of connecting networks or devices and (c) transmission to Ecosystem.DrGPCR.com third party vendors and hosting partners to provide the necessary hardware, software, networking, storage, and related technology required to operate and maintain the Services. Accordingly, the Customer acknowledges that he is solely responsible for adequate security, protection of Customer Information. Ecosystem.DrGPCR.com shall not be held liable towards the Customer for any unauthorized access or use of any of Customer Information, or any corruption, deletion, destruction, or loss of any of the Customer Information. 7. THIRD PARTIES: The Services may provide links or other access to other websites, and resources on the Internet. Ecosystem.DrGPCR.com has no control over such websites and resources, nor partner websites and resources, and Ecosystem.DrGPCR.com shall not be held responsible for and does not endorse such websites and resources. Such third parties, and not Ecosystem.DrGPCR.com, are the providers of other websites and resources and are solely responsible for providing any goods or services Customer purchases on third party or partner websites. The customer further acknowledges and agrees that Ecosystem.DrGPCR.com shall not be responsible or liable, directly or indirectly, for any damage or loss caused or alleged to be caused by or in connection with the use of such websites or resources. Any dealings Customer has with third parties found while using the Services are between the Customer and the third party, and the Customer agrees that Ecosystem.DrGPCR.com shall not be held liable for any loss or claim that Customer may have against any such third party. 8. OTHER SERVICES: The Customer may also enable various online services (application or external websites) to more effectively use Ecosystem.DrGPCR.com Services. To take advantage of these features, Ecosystem.DrGPCR.com may ask Customer to register for or log into the third-party services on the websites of their respective providers. By enabling third-party services within the Services, Customer is allowing Ecosystem.DrGPCR.com to pass Customer’s log-in information to these service providers. For more information please see our Privacy Policy. The manner in which third-party services use, store and disclose Customer Information is governed solely by the policies of such third parties, and Ecosystem.DrGPCR.com shall not be held liable or responsible for the privacy practices or other actions of any third party website. Ecosystem.DrGPCR.com shall not be responsible for the accuracy, availability, or reliability of any content made available in connection with third-party websites or services. 9. PAYMENT: As indicated in Section Three of this ATS, Customer is required to provide Ecosystem.DrGPCR.com with a valid Credit or Debit card through which membership fee payment shall be executed. Customer represents that it has full control of these Credit or Debit card and further agrees to hold Ecosystem.DrGPCR.com harmless for abuse or unauthorized use of these Credit or Debit Card by third parties 10. REPRESENTATIONS AND WARRANTIES: Customer represents and warrants to Ecosystem.DrGPCR.com that (i) Customer has full power and authority to enter into this ATS; (ii) Customer owns all Customer Information or has obtained all permissions, releases, rights or licenses required to engage in its billing, posting and other activities (and allows Ecosystem.DrGPCR.com to perform its obligations) in connection with the Services without obtaining any further releases or consents; (iii) Customer Information and other activities in connection with the Services, and Ecosystem.DrGPCR.com exercise of all rights and license granted by Customer herein, do not and will not violate, infringe, or misappropriate any third party’s copyright, trademark, right of privacy or publicity, or other personal or proprietary right, nor does Customer Information contain any matter that is defamatory, obscene, unlawful, threatening, abusive, tortious, sensitive to any particular social group or religion, offensive or harassing; and (iv) you are eighteen (18) years of age or older. 11. UNLAWFUL SERVICES: Ecosystem.DrGPCR.com shall not tolerate Customer(s), who knowingly or not, compromising the integrity of the Website by rendering Services in the Website that are false and untrue. In the event that Ecosystem.DrGPCR.com determines that any Services provided by any Customer in the Website can be found to be untrue or false, Ecosystem.DrGPCR.com reserves its sole right to terminate the membership of the Customer without further notice, and to take appropriate steps to ensure that any content of such Services is taken off the Website immediately. Ecosystem.DrGPCR.com reserves the right to contact any law enforcement authority in connection with the Services offered by a Customer considered to be unlawful. 12. TERMINATION: Customer has the right to terminate its account with the Ecosystem.DrGPCR.com at any time by sending a 30 (“Thirty”) day advance notice of termination to the company by email to Hello@DrGPCR.com. Ecosystem.DrGPCR.com reserves the right to (i) modify or discontinue, temporarily or permanently, the Services and (ii) refuse any and all current and future use of the Services, suspend or terminate Customer’s account or use of the Services and remove and discard any of Customer Information in the Services, for any reason. Ecosystem.DrGPCR.com shall not be liable to Customer or any third party for any modification, suspension or discontinuation of the Services. Ecosystem.DrGPCR.com may use good faith efforts to contact Customer to warn him prior to suspension or termination of Customer’s account by Ecosystem.DrGPCR.com. All accrued rights to membership fee payment(s) and the terms of Section 4 hereinabove shall survive termination of this ATS, and all fees paid to Ecosystem.DrGPCR.com are NON-refundable. 13. LIMITATION OF LIABILITY: In addition, to the extent permitted by applicable law, Ecosystem.DrGPCR.com (including our parent, subsidiaries, affiliates, officers, directors, agents and employees) is not liable, and Customer agrees not to hold Ecosystem.DrGPCR.com responsible, for any damages or losses (including, but not limited to, loss of money, goodwill or reputation, profits, or other intangible losses or any special, indirect, or consequential damages) resulting directly or indirectly from: Customer’s use of or his inability to use the Services; pricing or other guidance provided by Ecosystem.DrGPCR.com; delays or disruptions in the Services; viruses or other malicious software obtained by accessing, or linking to, the Services; damage to Customer’s hardware device from the use of the Services; the content, actions, or inactions of third parties, including items listed using the Services or the destruction of allegedly untrue or false information provided in the Services; a suspension or other action taken with respect to Customer’s account or breach of the ATS; the duration or manner in which the Customer’s listings appear in search results on the Website. SOME STATES DO NOT ALLOW THE EXCLUSION OF IMPLIED WARRANTIES OR LIMITATION OF LIABILITY FOR INCIDENTAL OR CONSEQUENTIAL DAMAGES, WHICH MEANS THAT SOME OF THE ABOVE LIMITATIONS MAY NOT APPLY TO CUSTOMER. IN THESE STATES, Ecosystem.DrGPCR.com LIABILITY WILL BE LIMITED TO THE GREATEST EXTENT PERMITTED BY LAW. Regardless of the previous paragraphs, in the event that Ecosystem.DrGPCR.com is found to be liable, the company’s liability to Customer or to any third party is limited to a maximum of $100 (“One Hundred Dollars”). 14. DISCLAIMER OF WARRANTIES: CUSTOMER AGREES THAT HE/SHE/IT IS MAKING USE OF THE SERVICES AT HIS/SHE/ITS OWN RISK, AND THAT THEY ARE BEING PROVIDED TO CUSTOMER ON AN “AS IS” AND “AS AVAILABLE” BASIS. ACCORDINGLY, TO THE EXTENT PERMITTED BY APPLICABLE LAW, Ecosystem.DrGPCR.com EXCLUDES ALL EXPRESS OR IMPLIED WARRANTIES, TERMS AND CONDITIONS INCLUDING, BUT NOT LIMITED TO, IMPLIED WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE, AND NON-INFRINGEMENT. 15. NO WAIVER: The failure of Ecosystem.DrGPCR.com to exercise or enforce any right or provision of this ATS shall not be a waiver of that right. Customer acknowledges that this ATS is a contract between Customer and Ecosystem.DrGPCR.com, and it governs Customer’s use of the Services and takes the place of any prior agreements between Customer and Ecosystem.DrGPCR.com. 16. ASSIGNMENT: Customer may not assign this ATS without the written consent of Ecosystem.DrGPCR.com. On the other hand, Ecosystem.DrGPCR.com may assign or transfer this ATS, in whole or in part, without restriction at its sole discretion. 17. INDEMNIFICATION: Customer agrees to indemnify, defend and hold Ecosystem.DrGPCR.com and its partners, agents, officers, directors, employees, subcontractors, successors, assigns, attorneys, advertisers, product and service providers, and affiliates harmless from any liability, loss, claim and expense, including reasonable attorney’s fees, related to Customer’s violation of this ATS or use of the Website or the Services. 18. GOVERNING LAW AND JURISDICTION: This ATS shall be governed by the laws of the State of New York without regard to the principles of conflicts of law. Unless otherwise elected by Ecosystem.DrGPCR.com in a particular instance, Customer hereby expressly agrees to submit to the exclusive personal jurisdiction of the federal and state courts of New York County, New York for the purpose of resolving any dispute relating to Customer’s access to or use of the Services. Any legal controversy or legal claim arising out of or relating to this ATS and/or the Services, with the exclusion of any legal action taken by Ecosystem.DrGPCR.com to collect or recover damages for, or obtain any injunction relating to intellectual property, and the Services, shall be settled solely by binding arbitration in accordance with the commercial arbitration rules of the American Arbitration Association. Any such controversy or claim shall be arbitrated on an individual basis, and shall not be consolidated in any arbitration with any claim or controversy of any other party. The arbitration shall be conducted in New York, New York, and judgment on the arbitration award may be entered into any court having jurisdiction thereof. Either party in this agreement may seek any interim or preliminary relief from a court of competent jurisdiction in New York County, New York, necessary to protect the rights or property of Customer and Ecosystem.DrGPCR.com pending the completion of arbitration. Each party shall bear one-half of the arbitration fees and costs. 19. SEVERABILITY: If any provision of this ATS is held to be invalid, void or for any reason unenforceable, such provision shall be struck out and shall not affect the validity and enforceability of the remaining provisions of the agreement. 20. PRIVACY: Please see the company’s Privacy Policy to understand how Ecosystem.DrGPCR.com collects and uses personal information. Please read carefully our Legal Policies and Disclaimers to understand how Dr. GPCR conducts business Affiliate Policy Content and Conduct Policy Content Guidance Privacy Policy Terms and Conditions Trademark Policy