During my Ph.D. at the International Max Planck Research School “The Leipzig School of Human Origins” Since 2014, I have led a research group at the Rudolf Schönheimer Institute of Biochemistry in Leipzig Our ultimate goal is to understand their role in immune cell function and cancer cell metabolism. " Dr Yamina expressed interest in attending a meeting about GPCRs and metabolism in the UK, but was unsure for the GPCR University, with the goal of providing a central hub for researchers in the field.

Research, 2014) and GPCRs (Feigin, et al., PNAS, 2014) in breast cancer pathogenesis, using mouse models They also discussed his research on cell polarity and its role in cancer progression, his work on G-protein Mike's Research on Cell Polarity and GPCRs in Cancer Mike shared his research on cell polarity and its GPCR Targeted Drugs and Gene Regulation in Cancer Cells Mike presented research on the effect of GPCR-targeted GPCRs and Cancer Immune Modulation Yamina and Mike had a discussion about their research on GPCRs, specifically

Silvio Gutkind on keeping a cancer research lab running at 10% occupancy, why rotation students act like Silvio Gutkind joins this resilience conversation from the UCSD Moores Cancer Center, where cancer patients His research spans GPCR signaling in cancer biology, head and neck squamous cell carcinoma, and the molecular Gutkind describes operating his cancer research building at 93–94% capacity during the early pandemic during the pandemic 03:30 Why cancer research couldn't stop 04:30 The NIH shutdown playbook 05:20 Writing

Trejo’s research program is to gain a thorough and mechanistic understanding of processes that control cell signaling by protease-activated receptors (PARs) and the impact on vascular inflammation and cancer Trejo’s research has focused on PAR1, which has important functions in hemostasis, thrombosis, inflammation , and cancer and is an important drug target. San Diego Trejo Lab Wikipedia LinkedIn Google Scholar Orcid Twitter UC San Diego School of Medicine Researchgate

GPCR is to accelerate GPCR drug discovery by sharing the latest research and technology advances in the My experience in basic research at several universities worldwide and early R&D at Novo Nordisk A/S allowed Trejo’s research program is to gain a thorough and mechanistic understanding of processes that control cell signaling by protease-activated receptors (PARs) and the impact on vascular inflammation and cancer , and cancer and is an important drug target.

At the end of his studies, he was awarded the Pfizer Prize for undergraduate research. At the MRC he developed novel prostate cancer therapeutics based upon his research into GPCR pluridimensional At the NIH he was the recipient of the coveted NIH ‘Bench-to-Bedside’ Translational Research Grant Award Stuart’s current research, in the Receptor Biology Lab, focuses on the development of novel GPCR-based This research stream is now forming the basis of a new technology-based start-up company, HeptOME , to

At the end of his studies, he was awarded the Pfizer Prize for undergraduate research. At the MRC he developed novel prostate cancer therapeutics based upon his research into GPCR pluridimensional At the NIH he was the recipient of the coveted NIH ‘Bench-to-Bedside’ Translational Research Grant Award Stuart’s current research, in the Receptor Biology Lab, focuses on the development of novel GPCR-based This research stream is now forming the basis of a new technology-based start-up company, HeptOME , to

At the end of his studies, he was awarded the Pfizer Prize for undergraduate research. At the MRC he developed novel prostate cancer therapeutics based upon his research into GPCR pluridimensional At the NIH he was the recipient of the coveted NIH ‘Bench-to-Bedside’ Translational Research Grant Award Stuart’s current research, in the Receptor Biology Lab, focuses on the development of novel GPCR-based This research stream is now forming the basis of a new technology-based start-up company, HeptOME , to

every tissue and implicated in conditions ranging from Parkinson's disease to ischemic heart disease to cancer For Comeo, who entered GPCR research without any background in the field and built her PhD around chemistry A trained medicinal chemist and pharmacist, her research focuses on the design and synthesis of fluorescent HEK cells are a known confound that still catch researchers out HEK cells endogenously express A2A and Medicinal Chemistry and Drug Discovery in the joint program of the University of Nottingham in the UK

Gloriam's research addresses a central challenge in the field: how to move from a bare protein sequence For Gloriam, this work began with a grandmother's cancer diagnosis and an early determination to develop His primary research focus is orphan GPCR biology, with particular emphasis on identifying endogenous The response exceeded his expectations: within years, researchers he had never met were greeting him He completed two postdocs in the UK at the EMBL-European Bioinformatics Institute and GlaxoSmithKline

Discover how GPR65 reshapes our understanding of GPCR signaling and its role in cancer, with Dr. unique academic journey—from early interests in medicine to his pivot toward pharmacology and GPCR research His research centers on the beta-2 adrenergic receptor and GPR65 , a proton-sensing receptor with promising implications in cancer biology. Yamina underscores the therapeutic potential of GPR65, especially in the context of cancer immunotherapy

neuropsychiatric disease: addiction, autism spectrum disorder, schizophrenia, bipolar disorder, and cancer For Boucard, adhesion GPCRs are not simply a research subject. through the lens of adhesion GPCR biology — addiction, autism spectrum disorder, schizophrenia, and cancer That discovery became the foundation of Boucard's independent research program. 4. why structures are finally coming 01:09:10 Synapse formation, addiction, autism, schizophrenia, and cancer

In pancreatic cancer, proton-sensing GPCRs such as GPR68 are dramatically upregulated in cancer-associated His research spans four decades of GPCR signaling, from cyclic AMP and adrenergic receptor biology to receptor discovery — Why hypothesis-free expression profiling reveals GPCRs that decades of targeted research cancer-associated fibroblasts — not the cancer cells themselves. Insel believes the training system pushes young researchers to narrow too early, at the cost of the cross-disciplinary

co-founders of GeneMode, on the ten billion dollars American labs waste every year — and why rebuilding research Most scientific research still runs on infrastructure built for a different century. He trained as a bioengineer and worked as a research scientist in stem cell and cancer labs before founding Excel is the default research tool because no one built a better one for scientists. scientists to make research more efficient.

<< Back to podcast list Strategic Partner(s) Exploring Career Paths in GPCR Research with Dr. After completing his Ph.D., he pursued research in genetics of metabolic regulation at the Institute Since 2021, Jacek has been working at Novo Nordisk at its research sites in the UK (Oxford) and the US of method development, integrity, and honesty in scientific research. their research interests and achievements, particularly in the field of GPCR.

GPCR is to accelerate GPCR drug discovery by sharing the latest research and technology advances in the Sachdev is an early career researcher in the National Institute of Diabetes and Digestive and Kidney As a young researcher fascinated by chemokine receptors, molecular pharmacology, drug discovery, and During that time, I investigated the effect of lung cancer-related mutations in the GAIN domain of the Currently serving as a Post Doctoral research fellow at Monash University, John plays a pivotal role

Lauren Slosky About Irfan Dhanidina "My interest in oncology research led me to pursue a BSc in Biology , I'm grateful to be working alongside the very talented team at Orion who translate important GPCR research Caron on the web UNC-Chapel Hill Department of Cell Biology and Physiology UNC Lineberger Comprehensive Cancer Slosky’s work has been recognized through several travel and research awards, including the William James In addition to research, Dr.

known ligand Extraoral expression of taste GPCRs - physiological roles in the airways, gut, heart, and cancer expressed not only in taste receptor cells on the tongue but in the upper airways, gut, heart, and certain cancer matchmaking challenge 15:53 - Extraoral expression - bitter taste receptors in the airways, gut, heart, and cancer consequences 41:58 - Taste GPCRs as drug targets - asthma, cardiac physiology, and early signals in cancer The Niv lab is also part of the Global Consortium for Chemosensory Research.

GPCRs drive cancer more often than the textbooks say. Dr. The emergence of cancer genomics has dismantled that framing. GPCRs don't need mutations to drive cancer. Cancer genomics rewrote the role of G proteins. "There are cancers that are driven by G proteins.

University of Utah School of Medicine in Salt Lake City, UT, and an investigator with the Huntsman Cancer Ben’s research focuses on Smoothened and other class F GPCRs which play essential roles in embryonic development and in cancer. Ben studied developmental and cancer signaling as a postdoctoral fellow with Philip Beachy at Stanford

A fresh look at computational GPCR research. << Back to podcast list Strategic Partner(s) Smells Like Like many, his path to GPCR research wasn’t linear—it evolved through academic exploration and mentorship discovery… I was in love with the topic.” – Alessandro Nicoli Working on docking and NMR studies for cancer-related From Researcher to Mentor: Growing Together Outside his research, Nicoli mentors students, manages interns Advice, Tools, and the Future of GPCR Research Nicoli offered advice to wet-lab scientists curious about

Professor Sunahara started his independent research career in the Department of Pharmacology at the University His main area of research focuses on the structural and pharmacological bases for hormone-mediated activation speculate that these aberrations in Galpha-s(l), specifically, may be involved in other pathologies such as cancer Roger Sunahara on the web UCSD Profile Google Scholar ResearchGate LinkedIn Dr.

UK, Wellcome Trust, and the Medical Research Council. She obtained her PhD in 2012 from the University of Oxford, where her research focused on the cellular Caroline moved to the University of Birmingham in 2018 to establish her research group investigating Her current research focuses on how metabolic GPCRs cross-talk and interact to regulate appetite and working on the study of membrane trafficking processes in pancreatic beta cells before returning to the UK

Angers established his independent research program in the Department of Pharmaceutical Sciences at the He is the recipient of the Canada Research Chair in Functional Architecture of Signal Transduction. His research program is developed to understand the signaling mechanisms underlying the Wnt and Hedgehog development of novel antibody molecules blocking and activating the Wnt pathway for the treatment of cancers of Toronto, an internationally recognized Research Institute bringing together multidisciplinary teams

Learn about Celtarys Research through the Dr. GPCR Ecosystem. Visit Website About Celtarys Research Celtarys Research develops and commercializes new chemical tools to welcome Celtarys Research to its partner ecosystem. , CEO of Celtarys Research. /celtarys-research Services & Expertise NEW!

My research aims to understand the mechanisms and consequences cell communication via heterotrimeric Our ongoing efforts have direct implications in cancer, embryonic development defects, and neurological Garcia-Marcos shares insights on transitioning from postdoctoral research to leading his own lab, addressing positions and the importance of networking, adaptability, and mentorship in fostering a collaborative research Garcia-Markos reflects on milestones in his research journey, reinforcing the passion that drives scientists

details the construction of an open-access GPCR-lipid raft database and reviews key findings from his research into how membrane microdomains modulate GPCR activity, the translational impact of taste receptors in cancer When integrating computational predictions with real-world pharmacological readouts If you see the research Sedaghat has accumulated over two decades of teaching and research in pharmacology, contributing as a His current efforts bridge teaching in Toronto and ongoing research, including the development of an

professor and chair of the Department of Computational and Quantitative Medicine (DCQM) at the Beckman Research She is also the Associate Director of the City of Hope Comprehensive Cancer Center. Dr. Vaidehi joined the Beckman Research Institute of the City of Hope in 2006 as a Professor and became chair

Passion is not a soft variable Bouvier frames this explicitly and without sentimentality: research has in Immunology and Cancer ( IRIC ) at the Université de Montréal. In 1989, he returned to Montréal as a professor of biochemistry and a scholar of the Medical Research Since 2001, he holds the Canada Research Chair in Signal Transduction and Molecular Pharmacology. He has supervised the research work of 75 graduate students and 40 post-doctoral fellows.

Following a post-doctoral period at Bristol Myers Squibb in Princeton USA, Andrew returned to the UK Funded through three consecutive Wellcome Trust Senior Research Fellowships Andrew established a reputation Now at the University of Glasgow, his primary research interests are focused on the rational design of In this Andrew runs a research laboratory of around 15 staff supported by basic research grants investigating research.