Lu GPCR-BSD: a database of binding sites of human G-protein coupled receptors under diverse states Fan Liu , Han Zhou , Xiaonong Li , Liangliang Zhou , Chungong Yu , Haicang Zhang , Dongbo Bu 🤩 Seriously

.; Liu, H.; Koehler, M.; Zhang, C.; Fan, H.; Alsteens, D. Lett. 2022 , 13 (2), 243–249. https://doi.org/10.1021/acsmedchemlett.1c00598 . (7) Liu, H.; Kim, H. Y.; Fan, H.; Wei, Z.; Zhang, C. Orthosteric and Allosteric Action of the C5a Receptor Antagonists.

Jürgen Wess and Liu Liu for their study on A novel function of the M2 muscarinic receptor Drs.

  (3) Fan, J.; Toth, I.; Stephenson, R. J.

Welcome GPCR Fans, Most pharmacologists are trained to chase targets.

Welcome back GPCR Fans, Clean data can still mislead if the underlying assumptions aren’t tested.

Welcome back GPCR fans, If your drug discovery strategy still relies on static GPCR models, you’re already

High-affinity agonists reveal recognition motifs for the MRGPRD GPCR Chunyu Wang ,  Yongfeng Liu ,  Marion

Welcome GPCR Fans,   In GPCR-targeted drug discovery, precision isn’t optional—it’s a requirement.

Among these ligands are orthosteric agonists such as alkylpyrimidine‐4,6‐diol derivatives (Liu et al.

Conformation- and activation-based BRET sensors differentially report on GPCR-G protein coupling Samuel Liu

Junke Liu et al. recently provided key insights into GPCR oligomerization and biased signalling, using

, 1195–1201. https://doi.org/10.1124/jpet.105.087254 DeWire, S.M., Yamashita, D.S., Rominger, D.H., Liu

Hey GPCR Fans, This week's breakthroughs are crucial for staying ahead in the rapidly evolving landscape

Welcome GPCR Fans,   Every discovery-phase decision you make shapes your entire pipeline trajectory—and

Liu-Chen, and J.R.

.; Liu, Z.-J. Crystal Structure of the Human Cannabinoid Receptor CB1. C.; Liu, Z.-J. Crystal Structure of the Human Cannabinoid Receptor CB2.

Welcome back GPCR fans, The pace of GPCR innovation is accelerating at a rate that can be difficult to

GPCR community members Build connections with other GPCR fans :) So much more to come!

Z., Wilderman, A., Katakia, T., McCann, T., Yokouchi, H., Zhang, L., Corriden, R., Liu, D., Feigin, M

Qian, Y., Ma, Z., Liu, C., Li, X., Zhu, X., Wang, N., Xu, Z., Xia, R., Liang, J., Duan, Y., Yin, H.,

GPCR community members Join the GPCR fan club and geek out with fellows! So much more to come!

Liu S, Anderson PJ, Rajagopal S, Lefkowitz RJ, Rockman HA.