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Results found for "Hannes Schihada"
- 📰 GPCR Weekly News, February 5 to 11, 2024
Magdalena M Scharf, Antonella Di Pizio, Ines Liebscher, Hannes Schihada, and Gunnar Schulte et al. on
- 📰 GPCR Weekly News, October 30 to November 4, 2023
Hannes Schihada and his lab team developed fluorescent analogues for real-time binding studies of orphan
- Accelerating GPCR Drug Discovery
Collaborative Partnership: I embed, contribute, and build solutions hand-in-hand with your team.
- 📰 GPCR Weekly News, April 29 to May 5, 2024
Today is also the first session of our hands-on workshop with Dr. Sam Hoare.
- From Student to Mentor: What Alessandro Nicoli Learned About Leading in Science
Alessandro admits he struggled at first with handing over parts of his projects, fearing mistakes.
- From Technician to Trailblazer: How Sokhom Pin Designed His Own PhD Program While Working in Industry
pursued experiments that were scientifically sound and directly publishable, a skill honed from years of hands-on
- Decoding Olfactory GPCRs: How AlphaFold and AI Are Changing the Game
Start with our GPCR training program and get hands-on with virtual tools shaping the future of drug discovery
- Beyond Clearance: The Strategic Power of Irreversible Drug Binding
Rethinking PK/PD Relationships With classical reversible drugs, effect and exposure walk hand in hand
- β-arrestin1 and 2 exhibit distinct phosphorylation-dependent conformations when coupling to the...
associate with the active parathyroid hormone 1 receptor (PTH1R) in different complex configurations ("hanging
- Drug Discovery Picks Up the Pace, Stays on Target
January 2022 "Voltaire argued, “Perfection is attained by slow degrees; it requires the hand of time.
- 📰 GPCR Weekly News, April 15 to 21, 2024
GPCR University hands-on workshop with Dr. Sam Hoare about this hands-on workshop HERE ⬇⬇⬇ Dr.
- Newly launched antibody libraries put hard-to-drug targets within reach
The drugs also target relatively low-hanging fruit: like cytokines or tyrosine kinase receptors.
- Gαs and Gαq/11 protein coupling bias of two AVPR2 mutants (R68W and V162A) that cause nephrogenic di
On the other hand, they showed the ability to couple with Gαq/11 protein and make Ca2+ mobilization at
- Transmembrane domains of GPCR dimers – a novel hot spot for drug discovery
(TMD), with the most compelling studies revealing that the transmembrane helices TM4 and TM5 on one hand , and TM1 and TM7 on the other hand, form possible dimerization interfaces (Ploier, B. et al. 2016; Dijkman
- 📰 GPCR Weekly News, April 8 to 14, 2024
GPCR University hands-on workshop with Dr. Sam Hoare about this hands-on workshop HERE ⬇⬇⬇ Dr.
- From GPCR Data Chaos to Decisive Action
they need clarity ✅ Yamina’s Corner helps teams move from data chaos to decisive action ✅ This is hands-on
- The Imprecision Problem: Why Your GPCR Drug Discovery Program Is Off-Track Before It Even Starts
Surely more hands will move the needle.
- Targeting Intracellular Allosteric Sites in GPCRs
On the other hand, selectivity could be achieved by merging both orthosteric and allosteric pharmacophores On the other hand, positive allosteric modulators that target intracellular allosteric sites can enhance
- Applications of Fluorescent Probes in Confocal Imaging of GPCRs: From Live to Fixed Cells
On the other hand, in fixed cells studies, it facilitates the structural context necessary to map receptor
- Radioligands vs. Fluorescent Ligands: Binding Assays
On the other hand, fluorescence signals can be easily monitored through confocal microscopy, plate readers
- GPCR Drug Discovery at Discovery on Target: Why This Track Is About More Than Receptors
Hearing Terry speak is more than an academic experience — it’s like being handed a new set of tools to
- Navigating the Signaling Network: RTK and GPCR Crosstalk Uncovered
On the other hand, RTKs play pivotal roles in growth factor signaling, regulating cell growth, differentiation
- How to Use Statistical Methods to Strengthen Every GPCR Drug Discovery Decision
t-test, ANOVA, F-test selection to power analysis that prevents underpowered studies, this module hands
- Fluorescence Polarization in GPCR Research
On the other hand, when the polarized light hits the bound fluorescent ligand, the slower rotation speed
- How a Failed Med School Dream Sparked a GPCR Biotech Revolution
Launching Blue was Ajay’s first hands-on experience with biotech entrepreneurship.
- 📰 GPCR Weekly News, April 1 to 7, 2024
GPCR University hands-on workshop with Dr.
- 📰 GPCR Weekly News, July 31 to August 6, 2023
Loan Facility with Hercules Capital Gene-to-structure and Europe give Proteros customers a winning hand
- Advantages of Fluorescent Probes in GPCR Assays
On the other hand, fluorescent ligands have a superior safety and environmental profile.
- 📰 GPCR Weekly News, April 22 to 28, 2024
GPCR University hands-on workshop with Dr.
- Chemokine receptor-targeted drug discovery: progress and challenges
On the other hand, Shall and Proudfoot excluded the idea of molecular redundancy, pointing out that,

















