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, is professor and chair of the Department of Computational and Quantitative Medicine (DCQM) at the Beckman she became the director of biomolecular simulations at the Materials and Process Simulation Center, Beckman Vaidehi joined the Beckman Research Institute of the City of Hope in 2006 as a Professor and became chair

Caron was an investigator of the Howard Hughes Medical Institute from 1992 to 2004, a member of the American

Caron was an investigator of the Howard Hughes Medical Institute from 1992 to 2004, a member of the American

From 2002-2006 he was a Howard Hughes Post-Doctoral Fellow at the University of Washington in Seattle

Caron was an investigator of the Howard Hughes Medical Institute from 1992 to 2004, a member of the American

Maudsley was awarded a Howard Hughes Medical Institute Fellowship to train with Professor Robert Lefkowitz

Maudsley was awarded a Howard Hughes Medical Institute Fellowship to train with Professor Robert Lefkowitz

Maudsley was awarded a Howard Hughes Medical Institute Fellowship to train with Professor Robert Lefkowitz

After moving to Rockefeller University with a Howard Hughes Medical Institute appointment, Tom advanced

Recognized with the Beckman Young Investigator Award, the Klingenstein-Simons Fellowship in Neuroscience

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He began his career in the late 1960s and has been an Investigator of the Howard Hughes Medical Institute

tone as they dive into Ian’s unique academic journey—from early interests in medicine to his pivot toward

The Shift Toward Technology-Driven Biology “Today’s students want to multiplex, miniaturize, and engineer Instead of focusing on a single receptor, students now gravitate toward platforms , biosensors , and

I really appreciate the way the podcast educates and mentors, particularly towards junior scientists

Highlights of the Week How Ligands Achieve Biased Signaling toward Arrestins Stéphanie Gaillard , Neha potentiates Kir7.1 to promote food consumption Reviews, GPCRs, and more How Ligands Achieve Biased Signaling toward

Understanding how ligand binding leads to specific signaling outcomes—particularly ligand bias toward “By counting the number of communication pathways toward G proteins versus arrestins, we began to see Communication routes toward G proteins differed from those toward arrestins.

inserting them at the top of the heavy chain CDR3, the library enters each panning campaign already biased toward Running multiple libraries in parallel moves the effective diversity toward 10¹² — the idea Aaron calls

the value of pursuing difficult scientific problems, and how curiosity about drug mechanisms led him toward Kim describes a personal inclination toward challenging research areas. “If someone tells me something is difficult, I tend to run toward it rather than away from it.” We're going to have to push him towards coming onto the podcast.

For Blanco-Redondo, the pull toward this work is not abstract. comparing research cultures across continents 08:30 - How adhesion GPCRs entered the picture, and the shift toward

There, I’ve been working towards understanding the molecular basis of G protein-coupled receptor desensitization Towards the end of his PhD, John became interested in understanding how proteins operate as large macromolecular

Scientific Themes of the Conversation Chemokine receptor redundancy and the shift toward functional selectivity moment 14:00 Rockefeller, CXCR3, and three splice variants that weren't the same 17:00 NIH and the pull toward

Towards the end, Mike mentioned that he stayed at Cold Spring Harbor even after his mentor left for Toronto Towards the end, Yamina asked about job opportunities in Mike's lab, to which Mike responded that potential

Even as the field pushes toward iPSC-derived somatic systems, HEK-cell signaling profiles of μ-opioid Today, Graciela and her team’s efforts are directed towards the characterization of the pharmacological

What You’ll Learn in This Episode How Ajay’s failed MD/PhD application rerouted his path toward a breakthrough

This conversation covers the arc of that career: the personal loss that drew Bouvier toward the sympathetic chemistry teacher who made synthesis feel real 04:44 A father's death at 39 from hypertension and the path toward

Launch Campaigns Strategic campaigns that actively drive scientist awareness and traffic toward your

activity at a wild-type FFA2 receptor, suppressible by an inverse agonist that then redirects signaling toward - and that an inverse agonist against that constitutive activity effectively redirects the receptor toward

Activation of a receptor can generate multiple signaling pathways, and different ligands can bias signaling toward Different ligands can bias signaling toward different pathways.

Towards the end, Claudia offered advice to junior scientists, suggesting that they explore different