Search Results

February 2022 "Switzerland Today, InterAx Biotech is pleased to announce that Carola Weiss has joined Carola Weiss is a Senior Executive with more than 20 years of international experience in the biopharmaceutical

February 2022 "InterAx Biotech AG and Boehringer Ingelheim take first steps towards collaborating to unlock orphan targets leveraging InterAx AI driven discovery platform. first-in-class small molecule agonists for a challenging orphan GPCR for a highly relevant therapeutic need. 💊 InterAx Biotech AG discovery platform was already successfully applied in projects with biopharmaceutical companies #ai #biotech #systemsbiology #drugdiscovery #gpcr #deeptech #orphandrugs #pharma #partnerships #AI4drugdiscovery

Every biotech founder fears the day the cash runs out. You track the burn rate. Here are the three most common sources of internal drift in early biotech teams: 1️⃣ Scientific versus Most biotech founders don’t suffer from having the wrong people. A soft skill. ✅ But in biotech, alignment is a multiplier. It’s how biotech companies move from drift to direction.

Joanne Waldstreicher to its Board of Directors GPCR Therapeutics launches multiple myeloma trial Salipro Biotech Japan, organized by LINK-J Jounce takes the cash under amended deal with Gilead on anti-CCR8 antibody InterAx Biotech Announces the Appointment of Seasoned Pharmaceutical Executive, Dr. SLAS2023 International Conference and Exhibition (February 25 - March 1, 2023). 2nd ERNEST Training School

Operational Highlights and Consolidated Results for the Third Quarter and First Nine Months of 2023 InterAx Biotech Announces Being the Recipient of a Highly Competitive European Grant to Fund Drug Development Scientific Meeting NEW January 16 - 19, 2024 | 23rd Annual PEP Talk February 3 - 7, 2024 | SLAS2024 International

Industry News InterAx Biotech to Apply its Leading AI and Cell Signalling Technology to Support Target Validation for a Sosei Heptares GPCR Discovery Program Salipro Biotech and DyNAbind Announce Milestone Addex Announces ADX71149 Phase 2 Epilepsy Clinical Study’s Independent Interim Review Committee Recommends

Most biotech pitches don’t fail because the science is weak. A clear biotech pitch answers three key questions immediately. Strong biotech pitches don’t just inform, they align. How to Fix the Gaps 👉 Fixing your biotech pitch doesn’t require a rebrand. A strong biotech pitch isn’t about saying more.

neutrophils by promoting an alternative-like polarization during bacterial infection Industry News InterAx Biotech's AI platform unlocks new drug designs for diabetes, obesity, and cancer Crinetics Pharmaceuticals

Upcoming events:  Practical sessions on GPCR internalization and soluble proteins; core meetings from Allosteric Interactions When should you push the native system—and when should you partner with it? with your topic suggestions 🆕 Weekly new releases to stay ahead of the science 🧠 Content built for biotech Eric Trinquet and his team at Revvity, that moment came when they watched GPCRs internalize in native GPCR scientists, translational pharmacologists, biotech discovery teams, and decision-makers who need

It’s a pattern we see far too often in early-stage biotech operations and startups. The 3 Golden Rules of Scientific Thinking — and Why They Break Down in Biotech Operations Leadership   In startups, waiting too long for certainty can destroy your momentum . 👉 Biotech founders often delay Scientific thinking will always be your strength, but it must be reshaped to serve your new role. 👉 As a biotech Attila runs focused strategy consultations for biotech founders  who are ready to lead with clarity,

that closed door lit the fuse for a career that would reimagine GPCR therapeutics — and lead to two biotech What followed was a scientific journey that now spans two biotech startups, and a bold reimagining of It was investor rejections, endless slide decks, and the steep learning curve of biotech business. Launching Blue was Ajay’s first hands-on experience with biotech entrepreneurship. Lessons From the Front Lines of Biotech Ajay’s experience in both early-stage biotech and academic science

July 2022 "G.CLIPS biotech is 2 years old today🎂. Looking forward for more 🎊 #team #grateful #biotech #work #birthdaycelebration" Read more at the source

The Gaps They Already See 👉 As a biotech founder, it’s easy to mistake volume for readiness . Clarity, not complexity, is what makes approval possible, and biotech sustainable. The Illusion of Readiness 👉 Many biotech founders walk into a pre-IND meeting with quiet confidence What the FDA Is Actually Optimizing For 👉 Biotech teams often treat the FDA like an evaluator. Reverse Engineering Your Path to FDA Approval Most biotech development plans are built forward : start

We’ve also highlighted the latest research on non-canonical internalization mechanisms of mGlu receptors GPCR scientists, translational pharmacologists, biotech drug discovery teams, and decision-makers who discovery, pharmacology, antagonism, competitive, non-competitive, Terry's Corner, Yamina's Corner, biotech development, pharmaceutical, scientific career Hashtags: #DrGPCR #GPCR #DrugDiscovery #Pharmacology #Biotech

October 2022 Intermolecular Interactions in G Protein-Coupled Receptor Allosteric Sites at the Membrane Interface from Molecular Dynamics Simulations and Quantum Chemical Calculations "Allosteric modulators binding location that raises many questions about the ligand interactions and stability, the binding In this work, we analyze interactions in the allosteric sites of the PAR2, C5aR1, and GCGR receptors The availability of polar atoms for interactions in such cavities can be assessed by water molecules

session, you’ll gain: ✅Clarity on Definitions:  What truly distinguishes orthosteric from allosteric interactions Allosteric Interactions Still Matter Orthosteric and allosteric interactions have been in pharmacology Recognizing how your ligand interacts with the receptor lets you predict safety margins, dose–response with your topic suggestions 🆕 Weekly new releases to stay ahead of the science 🧠 Content built for biotech If your team is still treating orthosteric and allosteric interactions as interchangeable, you’re leaving

the architect behind nearly all of Exscientia's partnerships and collaborations across pharma and #biotech⁠

It was about internal ignition. She moved from “What am I supposed to do?” She went from reluctant intern to global researcher shaping how we understand GPCR spatial signaling. For innovators and biotech strategists, stories like Michelle’s reveal how scientific leadership emerges For biotech innovators, those sparks are the future workforce and idea engines.

Discover how Revvity’s pHSense™ reagents enable real-time GPCR internalization detection A breakthrough GPCR internalization assay now featured in the Dr. Developed to address long-standing challenges in GPCR internalization assays , pHSense™ reagents  combine “The day we saw dose-dependent internalization in endogenous GLP1R cells—without microscopy—that was A GPCR Internalization Tool Designed for Real Research Needs Built on more than two decade A GPCR Internalization

This simple truth applies profoundly to the "go fast" culture in biotech. Learn to translate your program’s internal operational precision into a compelling, de-risked narrative I work with biotechs, VCs, and CROs to implement the framework that ensures every step forward is strategic

Upon agonist activation, the DOR-APEX2 complex is internalized and trafficked to the lysosome.

#biotech #lifesciences #appointment #GPCR #Oncology" Read more at the source #DrGPCR #GPCR #IndustryNews

Classically, GPCR internalization has been considered to lead to receptor desensitization. However, many studies over the past decade have reported that internalized membrane receptors can trigger The "internalized activation" provides a completely new understanding for the receptor internalization Here, this review summarizes different PTMs in GPCR internalization and analyzes their significance in GPCR internalization dynamics, internalization routes, postinternalization fates, and related diseases

Actions Adher’n Rise and ERNEST plus DFG-funded CRC1423 and RU2372) have joined forces to organize an international We aim to connect renowned international experts of the field with early career ‘rising stars’.

GPCRs are present in a range of conformations, and the binding of a ligand, as well as interactions with Depending on the specific functional outcome measured (e.g. activation, interaction with accessory proteins , dimerization, phosphorylation, internalization, or desensitization), the same drug acting on the same

"We are moving ahead with SLAS2022 as an in-person event with a hybrid component. We are closely monitoring any regulation changes from both Boston and Massachusetts with regard to in-person events. If there are any changes made that will impact our ability to hold the event in-person, we will notify the SLAS community as soon as possible. Please refer to our Safe Meeting guidelines for information about how you can participate in the event in-person. Don't miss the chance to present your innovative research at this year's conference. Poster abstracts for in-person and virtual presentations will be accepted through Monday, January 24." Register here

September 2022 Interacting binding insights and conformational consequences of the differential activity Here, using computational methods, we investigate the interacting determinants of CBD in two closely From our detailed characterization, we found particular interacting loci in the binding sites of the

GPCR scientists, translational pharmacologists, biotech drug discovery teams, and decision-makers who

#IPO #biotech #innovation #traitements #addiction #cannabis #Trisomie21 #Downsyndrome" Read more at the

September 2022 Ginsenoside Rg5 allosterically interacts with P2RY12 and ameliorates deep venous thrombosis