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Results found for "Nanome"
- Dr. Tim De Groof - Dr. GPCR Podcast
It’s not often when you get the best of both worlds - nano-bodies and #GPCRs.
- Decoding β-Arrestins: from Structure to function
signaling occurs within a 100 nm range from the point of origin, suggesting the formation of active "nano
- How Collaboration Sparked a GPCR Imaging Breakthrough in Chemical Biology
allow visualization of multiple GPCRs at once, and approaches capable of mapping receptor crosstalk at nanometer
- GPCR Collaboration: From Models to Medicine
If docking can suggest binding modes but can’t resolve nanomolar potency differences, they say so.
- Irreversible Drugs, Real Control: Design for Durable Target Engagement
Breakthroughs this week: nanomedicines targeting PAR2 for sustained analgesia; Emerging Voices in GPCR
- Fluorescence Polarization in GPCR Research
Nanomaterials Used in Fluorescence Polarization Based Biosensors.
- A robust and Efficient FRET-Based Assay for Cannabinoid Receptor Ligands Discovery.
Their binding affinity was assessed through radioligand binding, showing a nanomolar affinity for both
- Target Residence Time: The Hidden Driver of In Vivo Efficacy
hides the drug from its target When Potency Isn’t Enough Drug discovery teams are trained to chase nanomolar
- Pharmacology at Your Fingertips: Terry’s Corner Launches
With nanomolar affinity, high specificity, and a strong signal-to-noise profile, this non-radioactive
- Terry’s Corner, Celtarys' Leap, and the $7B GPCR Horizon
Probe CELT-419 Powers D3R Binding Assays Across Platforms Celtarys Research presents CELT-419, a nanomolar-affinity
- Dr. GPCR University registration is now open! Secure your spot now!
Oncology and Immunology Unveiling G-protein coupled receptors as potential targets for ovarian cancer nanomedicines
- Do You Believe AI Could Accelerate Drug Discovery?
receptors, with several compounds demonstrating subtype selectivity and high potency, some with sub-nanomolar
- Glyco-sulfo hotspots in the chemokine receptor system
It has been also reported that PSGL-1 glycosulfo peptide analogue GSnP-6 displays nanomolar affinity
- A new Kunitz-type snake toxin family associated with an original mode of interaction with the...
Key results: Eight additional MQs were identified with nanomolar affinities for the V2R, all antagonists
