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Results found for "Neel Freedman"

  • Science Needs Rigor, But Also Joy

    And we need that to do our best work.” – Ben Clements Mentorship Is the Engine of Science Ben chose

  • Finding needles in haystacks: Omass unveils pipeline aimed at tough-to-drug targets

    complexes and solute carriers, are relevant to immunology indications and rare diseases with high unmet need

  • From Lab Logic to Leadership: How Scientific Thinking Holds Back Biotech Operations

      ✅  You don’t need to abandon your scientific instincts. But you do need to adapt them if you want your startup to scale .     iterating, many scientific founders keep refining decks, processes, and team structures until they feel If you're feeling the friction — indecision, misalignment, slow momentum — it's not just operational. Whether you're refining your narrative, making tough tradeoffs, or simply feeling stuck, this session

  • The Hidden Burn: How Internal Misalignment Drains Your Biotech’s Runway

    . 👉 We’re talking about the type of quiet misalignment that appears to be progress but feels like confusion People don’t need to vote on everything. They just need to understand what game they’re playing. But because it ensures everyone is solving the same problem. ✅ If your biotech startup feels like it’ If you're feeling the friction — indecision, misalignment, slow momentum — it's not just operational. Whether you're refining your narrative, making tough tradeoffs, or simply feeling stuck, this session

  • How to Avoid the Most Common Gaps in Your Biotech Pitch

    2️⃣ Using buzzwords instead of clarity Words like “platform”, “breakthrough”, or “transformative” feel Frame the situation in terms of what’s at stake, whether that’s patient outcomes, time delays, unmet needs And when you focus on what your audience actually needs to hear, you don’t just earn attention, you earn If you're feeling the friction, indecision, misalignment, or slow momentum, it's not just operational Whether you're refining your narrative, making tough tradeoffs, or simply feeling stuck, this session

  • From Farm Fields to GPCR Discovery, GLP-1 and GIP

    Those courses didn’t feel like career-defining moments at the time — just requirements to pass. Early decisions don’t need to be perfect. They need to keep you moving. Curiosity compounds. You always need a scientific anchor — but you also need the courage to follow data where it leads. For real translational understanding, you need to see  the receptor in context.

  • The Imprecision Problem: Why Your GPCR Drug Discovery Program Is Off-Track Before It Even Starts

    Surely more hands will move the needle. If you want your program to survive, you need a Blueprint for Precision. Not next quarter. audit — before your next DMTA cycle costs another $200K Let’s unlock the momentum your GPCR program needs

  • Is Your GPCR Drug Discovery Program Built for Breakthroughs or Breakdowns?

    having to do 'everything at the same time ,' only for the youngest to wisely respond, 'No, you just need I understand that embracing a systematic approach can feel daunting, especially with the pressure to accelerate discovery . 🚀 Book your free 30-minute strategy call Let’s unlock the momentum your GPCR program needs

  • Understanding the Journey: Catherine Demery's Path to Addiction Science

    Watch Episode 172 What happens when the career you planned no longer feels right? It was mostly just because, I need to be back in the lab.” It’s rigorous pharmacology, but deeply tied to urgent public health needs.

  • Curve Shifts Don’t Lie, But Your Eyes Might

    You don’t need sharper eyesight. You need statistical methods that tell you, with confidence, whether the effect you’re seeing is real In This Session, You’ll Gain: ✅ The ability to calculate how many replicates you really  need for 95% What you need is a number that tells you whether those differences are real. How Many Replicates Do You Really Need? The second trap is habit.

  • Your GPCR Program Decisions Depend on Good Data Interpretation

    week: industry insights, event updates, jobs, and classified publications—curated for scientists who need on leads that fail later in development In this exclusive session, Kenakin gives you the frameworks needed GPCR the best for the sake of promoting more educational opportunities that are sorely needed in the GPCR Premium is designed for scientists who need the right intelligence, fast—without noise, distractions Scientists, drug discovery teams, and pharmacologists who need curated, career-relevant updates.

  • From GPCR Data Chaos to Decisive Action

    This is embedded consulting for biotech and VC teams who need to move fast —without compromising scientific key decision. 🚀 Book your free 30-minute strategy call Let’s unlock the momentum your GPCR program needs insights = wasted time ✅ You can’t fail fas t if you can’t see the problems early ✅ Most teams don’t need more data— they need clarity ✅ Yamina’s Corner helps teams move from data chaos to decisive action

  • Conjugation Strategies for Probe Development

    NHS esters are not very stable even in aqueous environment but they only need a slightly basic medium Not only do they work in aqueous medium, but also in aprotic solvents like DMF, where you will need to biggest advantage is the presence of Cys residues in proteins, although sometimes S-S bridge reduction is needed There’s no need for any catalysts; all reagents will be incorporated in the structure of the final compound

  • Radioligands vs. Fluorescent Ligands: Binding Assays

    The choice between these two depends on the results needed – but in case they are similar, fluorescent If you are curious about fluorescent probes, fluorescent probe design or GPCR tools, feel free to contact

  • How Collaboration Sparked a GPCR Imaging Breakthrough in Chemical Biology

    David Hodson needed molecules that were only one synthetic step beyond what JB was already making. It was a shared sense of fun, the kind of scientific joy that makes late-night imaging sessions feel lighter and big failures feel solvable.

  • Why Kinetics Matter More Than Kd in GPCR Drug Discovery

    Terry Kenakin’s latest lecture in Terry’s Corner  delivers exactly what your discovery teams need now Redefine your playbook:  Why Serafini believes that pain research needs to start from clinical phenotype GPCR Premium is designed for scientists who need the right intelligence, fast—without noise, distractions GPCR scientists, translational pharmacologists, biotech drug discovery teams, and decision-makers who need Don’t Fall Behind—Access the Edge You Need 👉 Ready to sharpen your discovery decisions?

  • From Snapshots to Predictions: Why Mechanism of Action Matters

    You don’t need more data—you need a way to translate snapshots into predictions. The lesson: models don’t just need data. They need the right data . , pharmacologists refining fundamentals, scientists challenging legacy assumptions, and leaders who need

  • How GPCR Collaboration Built an Innovation Engine

    project-level thinking to platform-level strategy  — a critical shift for GPCR biology, where complex systems need Collaboration isn’t a feel-good story.

  • When Pain Becomes a Catalyst: How Personal Experience Redefined One Scientist’s Mission

    "When you talk to patients that have an unmet need, you learn things that no one is thinking about in how personal pain can lead to professional purpose — and why the next generation of pain researchers needs

  • Building Backwards: Why Top-Down Models Could Revolutionize Pain Research

    Takeaway We don’t need better in vitro data — we need better models of reality. Dr.

  • Competitive vs Non-Competitive GPCR Antagonists: How to Interpret Pharmacology Data with Confidence

    Don't let misconceptions about receptor binding kinetics slow your progress—gain the clarity you need Our weekly curated news and expert frameworks provide the actionable intelligence you need to make sense GPCR scientists, translational pharmacologists, biotech drug discovery teams, and decision-makers who need Don’t Fall Behind—Access the Edge You Need 👉 Become a Premium Member Today ➤ Already a Premium Member Gain the insights, tools, and connections you need to excel in your field and make your mark.

  • Molecular creativity in drug discovery

    GPCR scientists, translational pharmacologists, biotech drug discovery teams, and decision-makers who need ’s breakthroughs—and avoid delays others won’t see coming. 👉 Don’t Fall Behind—Access the Edge You Need GPCR the best for the sake of promoting more educational opportunities that are sorely needed in the

  • How Advanced GPCR Kinetics Sharpen Decision Making (and Save You Time)

    If you need to brief leadership, plan experiments, or time a move in the market or your career, Premium GPCR scientists, translational pharmacologists, biotech discovery teams, and decision-makers who need ’s breakthroughs—and avoid delays others won’t see coming. 👉 Don’t Fall Behind—Access the Edge You Need Kenakin is a masterful teacher and communicator." — DrGPCR University Attendee Everything you need to

  • The Perils and Guardrails of Modifying Signalling Proteins in Bioassays

    Freeman BB, 3rd, Yang L, Rankovic Z. Estimated Research and Development Investment Needed to Bring a New Medicine to Market, 2009-2018.

  • What If the Most Important Part of Your Drug Isn’t What It Binds—But What It Does?

    re stuck trying to figure out why your lead compound looks promising in vitro but flops in vivo, you need

  • Pharmacology Isn't What You Think—It's So Much More

    contradictory This lesson isn’t just academic—it’s practical knowledge every early-stage scientist needs

  • How to Design GPCR Drugs That Work in Vivo: Strategy, Tools, and Insights

    It’s a response to unmet scientific needs: Replace microscopy-heavy workflows with no-wash, live-cell Podcast, the Revvity team built pHSense™ from the ground up by listening to what GPCR scientists actually need—and GPCR scientists, translational pharmacologists, biotech discovery teams, and decision-makers who need

  • Integrating Fluorescent Ligands into Flow Cytometry: Enhancing GPCR Analysis Beyond Traditional Antibody Staining

    Fluorescent ligands based on small molecules bind to the functional sites of receptors in live cells, no need No need for fixation and permeabilization This step can modify receptor conformation and affect downstream Compatibility with live cells No need for fixation of permeabilization.

  • How to Use Statistical Methods to Strengthen Every GPCR Drug Discovery Decision

    Power analysis tells you exactly how many replicates you need for 95% confidence. GPCR scientists, translational pharmacologists, biotech discovery teams, and decision-makers who need ’s breakthroughs—and avoid delays others won’t see coming. 👉 Don’t Fall Behind—Access the Edge You Need

  • Dr. GPCR Spotlights Revvity’s pHSense™ Internalization Tools

    A GPCR Internalization Tool Designed for Real Research Needs Built on more than two decade A GPCR Internalization Tool Designed for Real Research Needs s of GPCR assay innovation , pHSense™  was developed to overcome

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