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- Enhancing GPCR Research Outreach | Dr GPCR University early-bird registration ends soon!GPCR University Early-Bird Registration Open for Premium Members! 
- Dr. GPCR University registration is now open! Secure your spot now!GPCR University Early-Bird Registration Now Open for Premium Members! regulators Functional consequences of spatial, temporal and ligand bias of G protein-coupled receptors Inverse 
- 📰 GPCR Buzz: August 5-11, 2024 | Top Highlights from DrGPCR University!GPCR University offers two live courses this fall that you won’t want to miss. 
- Professor Charlotte Deane Joins Exscientia as Chief Scientist of Biologics AIJanuary 2022 "OXFORD, England--Professor Charlotte Deane, Ph.D., of the University of Oxford, has joined She has held numerous senior roles at the University of Oxford, where she is currently Professor of Structural Bioinformatics and leads the University’s Protein Informatics group. Professor Deane holds a B.A. in Chemistry from the University of Oxford and a Ph.D. in Biochemistry from the University of Cambridge." 
- GPCR News Flash! Top Updates You Can't-Miss! + University CheatSheet is finally available! ❄ Dec 2 - 8, 2024We've got an early holiday treat for you: The University CheatSheet ! restricted chemogenetic system Hye Jin Kang , Brian E Krumm , Adrien Tassou , Bryan L Roth , et al. 🕶 University 
- 2nd IRN i-GPCRnet, September 30 to October 1st, 2022. University of Wurzburg, GermanyAugust 2022 "We are happy to announce you our 2nd IRN i-GPCRnet meeting that will be held at the University 
- John Streicher talks about his work on terpenes found in cannabis as these may be a novel way to ...April 2022 John Streicher talks about his work on terpenes found in cannabis as these may be a novel way to treat pain without the negative side effects "Many people are familiar with cannabis, but John Streicher, PhD, takes a closer look at the plant’s aromatic chemical compounds called terpenes. These compounds may be a novel way to treat pain without the negative side effects of cannabinoids or opioids." Read more at the source #DrGPCR #GPCR #IndustryNews 
- Targeting the M1 muscarinic receptor in neurodegenerative diseasethe Keystone Symposia GPCR Conference, a summary of work performed both at Sosei Heptares and Glasgow University 
- Inverse Agonists, Lymphatic Fixes & β-arrestin TricksGPCR University - A fast-reference guide for you! The Dr. GPCR University Cheatsheet is your quick-start guide to everything we offer—no downloads, no digging Publication Highlights — Minimal Structural Variation of GPR84 Full Agonist Causes Functional Switch to Inverse 
- Diversity and specificity in location-based signaling outputs of neuronal GPCRsHowever, it is becoming increasingly clear that GPCRs show great diversity in their intracellular location Here we will discuss recent studies on the diversity of location, effectors, and signaling of GPCRs, 
- Structural basis for receptor selectivity and inverse agonism in S1P5 receptorsresolution room temperature crystal structure of the human S1P5 receptor in complex with a selective inverse previously published S1PR structures in complex with antagonists and agonists, our structure with S1P5-inverse agonist sheds light on the activation mechanism and reveals structural determinants of the inverse agonism 
- What If Your Data is Lying to You? The Calcium Assay DilemmaBecause when true pharmacological profiling is essential—like detecting partial or inverse agonism—calcium 
- Aβ peptides stabilize GPCRs in inactive form and trigger inverse agonism in Alzheimer's diseaseAugust 2022 "Several G-protein coupled receptors (GPCR) are upregulated in Alzheimer's Disease (AD), which ought to facilitate neurotransmission, and improve cognition. Yet, despite this upregulation, associated physiological effects are not observed in AD patients. This paradox solicits urgent attention to find a suitable justification for disturbed neurotransmission in AD. This article focuses on the role of Aβ granules and their possible interaction with GPCRs that modulate neurotransmission and AD progression." Read more at the source #DrGPCR #GPCR #IndustryNews 
- From Venice to Virtual Molecules: Alessandro Nicoli’s Unexpected Journey into Computational Chemistryof scientific curiosity, chance opportunities, and the unlikely road that led him to the Technical University : Molecules and Mentors Alessandro began his academic life studying pharmaceutical chemistry at the University Explore the GPCR University or enroll in Terry's Corner for GPCR Courses led by Dr. 
- Ben Clements on Rescuing Opioids with GPCR ModulatorsGPCR Podcast, Ben, a postdoctoral fellow at the University of Michigan, walks us through how positive Start learning with our GPCR University today. _______________ Keyword Cloud: GPCR research community 
- Integrating Fluorescent Ligands into Flow Cytometry: Enhancing GPCR Analysis Beyond Traditional Antibody Stainingfluorescent tags to study biased signaling pathways, improving our understanding of GPCR functional diversity Flow Cytometry validation performed in the Oncological Pharmacology Laboratory of the University of Turin Biomedicines. 2021 Nov 4;9(11):1613. doi: 10.3390/biomedicines9111613 University of Virginia Flow Cytometry Charlottesville (VA): University of Virginia; [cited 2025 May 16]. 
- Assay Volume Control: Your GPCR Drug Discovery Power Leverhow dialing receptor expression/coupling up or down reveals hidden partial agonism, “silent” agonism, inverse Jens Carlsson (Uppsala University) joins Yamina to explore how computational modeling is evolving from the sake of promoting more educational opportunities that are sorely needed in the field." — DrGPCR University Become a Premium Member today. ➤ 🎓 Full GPCR University + 🔬 200+ expert talks 🗞️ Weekly research, 
- Understanding the Journey: Catherine Demery's Path to Addiction ScienceAfter excelling in the PCAT and gaining admission to pharmacy school at the University of Michigan, it After two years in industry, Catherine enrolled in a master’s program in pharmacogenomics at Manchester University to the Opioid Questions That Mattered Now, as a PhD candidate in the Traynor and Anand labs at the University 
- 📰 GPCR Weekly News, March 11 to 17, 2024Garcia-Marcos, et al. for their work on Direct interrogation of context-dependent GPCR activity with a universal GPCR University Save the date for our upcoming workshop, starting May 9th, 2024, featuring Dr. GPCR University was tremendously successful. Methods & Updates in GPCR Research Direct interrogation of context-dependent GPCR activity with a universal 
- 📰 GPCR Weekly News, April 29 to May 5, 2024GPCR University content coming soon. 
- 📰 GPCR Weekly News, May 20 to 26, 2024GPCR University Today marks the final day of the Dr. GPCR University workshop on Advanced Data Analysis for GPCR Pharmacology, led by the esteemed Dr. and more Flipping the GPCR Switch: Structure-Based Development of Selective Cannabinoid Receptor 2 Inverse CB1 receptor antagonists disclosed in Inversago patent Orion Biotechnology will be attending BIO 2024 Antiverse 
- 📰 GPCR Weekly News, March 25 to March 31, 2024GPCR University Get ready for our next Dr. GPCR University hands-on workshop with Dr. our forums, private groups, and all Ecosystem members Extended early bird discounts on future Dr.GPCR University , and more Advances in GPCRs: Structure, Mechanisms, Disease, and Pharmacology Industry News Monash University 
- Irreversible Drugs, Real Control: Design for Durable Target Engagement." — DrGPCR University Attendee 🚀 Join now — and learn to design drugs that don’t just bind tighter, Become a Premium Member today. ➤ 🎓 Full GPCR University + 🔬 200+ expert talks 🗞️ Weekly research, 
- 🎧Episode 85 of the Dr. GPCR podcast is here!Nicholas Holliday and how he has combined his university role with his leadership of Excellerate Bioscience 
- 📰 GPCR Weekly News, January 8 to 14, 2024GPCR University February 8 - 29: Join Dr. GPCR University's live course with Dr. Terry Kenakin. GPCR University and save your spot today! Dr. 
- How to Design GPCR Drugs That Work in Vivo: Strategy, Tools, and InsightsVirginia; Novo Nordisk flags drug trial promise; Nanobody sensor reveals β-arrestin conformational diversity GPCR and the offered resources in my work sphere." — DrGPCR University Attendee GPCR innovation doesn jobs—trusted by scientists, teams, and biotech decision-makers. 🚀 Join Premium Today & Enjoy ➤ 🎓 Full GPCR University 
- Are You Guessing or Forecasting? Master GPCR Pharmacologic Models Before It’s Too LateGPCR University Learner Dr. GPCR Podcast - Surviving Discovery’s Gauntlet Dr. 
- Cancer Research UK and Sosei Heptares sign agreement to advance cancer immunotherapy candidate ...to treat a wide range of cancers in combination with other immunotherapies Tokyo, Japan, London and Cambridge 
- Sosei Heptares Announces Antitrust Clearance of License Agreement with Neurocrine BiosciencesDecember 2021 "Tokyo, Japan and Cambridge, UK, 24 December 2021 – Sosei Group Corporation (“Sosei Heptares 
- 📰 GPCR Weekly News, January 22 to 28, 2024GPCR University We're thrilled to share that all spots for the Applying Pharmacology to Drug Discovery GPCR University have been filled! Thank you for the overwhelming response. and Hemicyanine as a "Turn-On" Fluorescence Probe Industry News Domain Therapeutics awarded Hospital-University 















