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The broader argument Arey has spent his career developing is that biased signaling is not a GPCR-specific drug discovery The erosion of pharmacology training in pharmaceutical research - and why it matters Career Verify against the published episode before using for navigation. 00:00 Introduction 01:48 Career overview Brian has contributed to the discovery or development of 5 marketed drugs through his work spanning molecular

Career coach Lauren Solano on the skills PhDs undersell, the careers they don't know exist, and the introspection to bench scientists, ranging from medical science liaison and clinical research roles to business development Scientists navigating a career change are better served mapping careers by tasks and functions first, career coaching 07:56 Loved it, loathed it — the introspection exercise 10:29 Career options PhDs rarely Lauren Celano on the web LinkedIn Propel Careers Email: Lauren@propelcareers.com Dr.

mispronunciations, cultural differences, and the importance of a multidisciplinary approach in drug development discussed their research interests, particularly in the field of GPCR, and the importance of method development discussed their professional backgrounds, highlighting the benefits of a multidisciplinary approach in drug development Jacek's Career Journey and Advice Jacek and Yamina discussed Jacek's career journey, focusing on his They also highlighted the importance of method development, integrity, and honesty in scientific research

Sokhom Pin shares how he built a biotech career around GPCRs, designed a custom PhD path, and led teams through empowerment and purpose. << Back to podcast list Strategic Partner(s) GPCR Pharmacology, Career “That’s the moment that changed my entire career. I was trusted to build a team from scratch.” story underscores how something as simple as forwarding a resume or reaching out for coffee can change careers For any scientist navigating career uncertainty—his story is both roadmap and inspiration.

Karine Pichavant , I contributed to the development of a drug to treat hypovolemic shock after severe Chemistry which described the molecular mechanisms of MRAP2 regulation of the GHSR1a, and where I notably developed I also invested a tremendous amount of time in developing my leadership skills. opportunities, and seriously weighing strengths of career options across sectors; however, academia I want to connect more trainees with diverse career resources to support professional decision-making

these benefits are designed to enhance your research experience and keep you informed about the latest developments Free Apply as an Instructor Developing Countries Full Premium access for researchers in developing countries "Will this really help my career?" Yes. Do you offer discounts for students or developing countries? Yes. Members from developing countries can join for $24.99/year.

Eric Trinquet shares the inside story behind the development of pH Sense, Revvity’s latest innovation and product development, Eric takes us through the highs, failures, and scientific “aha” moments that Inside This Episode How Eric and his team reimagined rare earth complexes to develop pH-sensitive probes and hit the “overexpression ceiling,” Balanced scientific rigor with the unpredictability of product development photophysics and fluorescence chemistry, Eric transitioned into the GPCR field through hands-on assay development

They also explored the possibility of developing an ecosystem for the GPCR University. Academia, Career Journeys, and Advice Yamina and Claudia discussed Claudia's career journey in academia Yamina highlighted the challenges of career choices, especially when family situations are involved. Claudia also mentioned the significant experiences that shaped her career trajectory, such as her time Developing a Research Ecosystem at GPCR University Yamina and Claudia discussed developing an ecosystem

Yekkirala shares the pivotal moments that transformed him from a curious PhD student into a GPCR drug developer Young scientists are hungry for alternate career paths. Episode How Ajay’s failed MD/PhD application rerouted his path toward a breakthrough GPCR research career scientists interested in translational innovation Biotech investors and strategic leaders seeking new drug development Ajay Yekkirala is a molecular pharmacologist, biotech founder, and scientist whose career has been defined

To further develop these ideas, I joined the lab of Dr. John's Chemistry Olympiad Journey John shared his experiences in high school, where he developed a keen working on a project involving receptor kinases and collaborating with other postdocs in the lab to develop Yamina agreed and sought advice from John on career progression in academia. John suggested starting preparations a year to two years ahead due to the time needed to develop ideas

They also discussed the ongoing developments in the GPCR field, the upcoming adhesion GPCR consortium and career paths, with a focus on their experiences in academia. He explained that initially, the field lacked adequate tools, and his lab had to develop new techniques Yamina expressed her appreciation for Demet's work and asked about the development of the GPCR field GPCR Field and Naming Convention Discussion Demet and Yamina discussed the ongoing developments in the

His independent research focuses on developing accessible mathematical tools for kinetic analysis of The effect on Hoare's confidence — and ultimately his career — was not. He describes it as one of the moments his career most depended on. 5. consultancy and data analysis company supporting pharmaceutical, life science, and academic scientists in the development He specializes in kinetic analysis of drug action and is known for applying binding kinetics to the development

spans the identification of 26 novel human GPCRs from genome sequence data to the development of GPCRDB For Gloriam, this work began with a grandmother's cancer diagnosis and an early determination to develop He maintains and develops GPCRDB, a continuously updated database and tool platform that integrates structural For me, the actual development - that's the thing. And that's the fun part." His group recently developed an online resource of biased ligands and pathway effects to advance the

Marro’s career spans big pharma and biotech, encompassing functional assay development, GPCR internalization Scientists seeking practical advice on career pivots between academia, pharma, and biotech. Marro’s career advanced through roles at Novartis and Tectonic Therapeutic, contributing to projects With over two decades in drug discovery, he has established expertise in early phase functional assay development

discussed the importance of hiring based on differentiation, impact, and interest, the need for workforce development will share notes about PRISM and presentability with Arthur. - Arthur will share the story of PRISM's development Lastly, they discussed the growth and development of the Monash Institute of Pharmaceutical Sciences, significance of fundamental discoveries, the role of biotech, and the need for efficiency and process development They also discussed the disruption within the pharmaceutical sector, the importance of workforce development

discussed the importance of hiring based on differentiation, impact, and interest, the need for workforce development will share notes about PRISM and presentability with Arthur. - Arthur will share the story of PRISM's development Lastly, they discussed the growth and development of the Monash Institute of Pharmaceutical Sciences, significance of fundamental discoveries, the role of biotech, and the need for efficiency and process development They also discussed the disruption within the pharmaceutical sector, the importance of workforce development

contributions to multiple clinical programs including preclinical models that supported the apixaban development in early discovery Intellectual humility and the dynamics of cross-functional drug discovery teams Career "All the key discoveries I've made in my career were based initially on intuition. "Yeah, it inhibits your career. I will say that." "I've spent 25 years pushing back against that. Brian has contributed to the discovery or development of 5 marketed drugs through his work spanning molecular

Exploring discoveries, careers, and ideas shaping human health. In each episode, we sit down with leading experts to explore their career journeys, groundbreaking discoveries Fill out this form Be our Guest In each episode, we chat with an expert about their career trajectory I'm genuinely interested to see how it evolves and grows over time, as I feel it has the potential to develop

Using radioligand binding assays developed for the beta-adrenergic receptor system, his lab purified, His lab developed the GRK (G protein-coupled receptor kinase) family and discovered the beta-arrestins demonstration of GPCR structure — The methodological progression from iodinated hormone binding to radioligand development Choosing that problem required betting a career on a concept that the field's own architects considered It was that serendipitous event that basically changed the entire course of my life and career."

Summary Arthur's Career Journey and Allosteric Receptors Yamina and Arthur discussed Arthur's career The conversation ended with Arthur's ongoing research and his development of a new operational model. Allosteric Modulation and Hybrid Molecules Arthur and Yamina discussed the development of an operational also discussed the potential of certain drugs, like flumazenil, as 'nails' or compounds that could be developed and Reproducibility Yamina and Arthur discussed the concept of a target product profile (TPP) in drug development

I have 10 years of experience in the development and management of R&D projects and teams in the field I have developed my expertise in the field of pharmacology and biochemistry of GPCR and the crucial role I developed G.CLIPS biotech's innovative technology as a synthesis of the different knowledge, experiences , and know-how from the different stages of my career.

Together with Irina Kufareva , UCSD, her team developed a novel approach to identifying ligands for orphan GPCRs by developing a powerful new computational tool for identifying ‘surrogate’ ligands (borrowed Her career goal is to leverage this expertise to establish a research program that takes orphan GPCRs

Advance your GPCR research career with Dr. GPCR University. stage who want to stay sharp, connected, and supported. 🎓 Early-career researchers Find your footing Aside from his vast experience in drug development, not to mention his extensive publication record, "Will this really help my career?" Yes. Summit A global gathering of researchers and professionals showcasing the latest developments in GPCR

Mid-career, he has worked in finance and developed high-frequency trading systems. early-stage medical device start-up and in 5 years was responsible for project R&D and managing a focused development

Networking & Career Growth – Overcoming introversion, the importance of talking to people, and how networking Tune in to hear how Dmitry navigated his career, the challenges of studying GPCRs, and why talking to In 2021 he co-founded Z7 Biotech, developing and providing innovative GPCR drug screening and precision

From the development of BRET-based biosensors that revealed receptor behavior in living cells, to the His lab's contributions include the development of BRET (Bioluminescence Resonance Energy Transfer) technology evidence in living cells - which didn't exist yet and would take longer than the revision window to develop pharmacological chaperones, his work on bioluminescence resonance energy transfer (BRET) resulted in the development a member of the lab, I am humbled to have been able to work with him and his team and use the tools developed

Clements The Power of Inclusion in the GPCR Field This episode kicks off with a celebration of early-career importance of diverse voices in the GPCR community: “It’s been a very difficult path to get more early-career His journey highlights the transition from general drug development to a deep dive into G protein-coupled mentorship, open communication, and peer learning — especially from undergraduate trainees — shape his development Clements' work is primarily focused on translational developments of small molecule therapeutics, and

During her postdoctoral work, she developed a computational framework that maps communication pathways Nivedha developed computational approaches to quantify ligand bias by analyzing communication routes The lab had developed software to analyze these communication pathways. It also showed me how important GPCR research is in pharmaceutical development. That moment led to the development of the computational method we later published.

Sachdev is an early career researcher in the National Institute of Diabetes and Digestive and Kidney Her research centers on developing nanobody-ligand conjugates to target GPCRs, with a focus on receptors

They also discussed Badr's career trajectory, the importance of self-learning, collaboration, and delegation Yamina will continue to develop and manage the Dr. understanding how Badr’s experiences influenced his current role, and Badr stressed the need for individuals to develop Yamina’s Podcast Journey and Career Advice Yamina discussed how her podcast on chemokine ligands led Yamina advised him to consider career options after his postdoc and adapt to different systems.