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Strategy: From Personal Pain to Scientific Purpose Dr. pain following repeated surgeries for a pilonidal cyst. pain, epigenetics, translational models. Venetia Zachariou's lab to study the effects of chronic pain and addiction/withdrawal on the mesocorticolimbic pain and affective comorbidities.

GPCR Title: Characterization of Novel Opioid-Neurotensin Bifunctional Ligands Designed to Target Pain interested in characterizing novel G protein-coupled receptors (GPCRs) ligands for the treatment of chronic pain but also in deciphering cellular signaling pathways associated with the physiological effects observed

“We’re enhancing the powerful pain-relieving effects of opioids while limiting respiratory depression He is particularly excited by the novel application of PAMs in chronic and neuropathic pain models , Discovering breakthrough results in neuroma pain models via a spontaneous collaboration. pain and opioid use disorder. pain.

Biotech founder Ajay Yekkirala shares how AI, GPCRs, and bold questions are driving next-gen pain therapeutics breakthrough GPCR research career The inside story behind founding Blue Therapeutics and targeting supraspinal pain Woolf at Boston Children’s Hospital and Harvard Medical School, where he deepened his understanding of pain Driven by the opioid crisis and the lack of non-addictive pain treatments, Ajay co-founded Blue Therapeutics , a biotech startup focused on targeting supraspinal GPCRs for chronic pain.

Nigel Bunnett at the NYU Pain Research Center as a postdoctoral researcher. research focuses on investigating GPCR signaling and trafficking in the context of inflammation and chronic pain. Next Steps Badr will continue focusing his research on GPCRs involved in pain and inflammation during Badr shared his passion for GPCR signalling and regulation, specifically in the context of pain and inflammation

studies encompassing neurological and psychiatric disorders, cardiovascular disease, obesity, diabetes, chronic pain and addiction.

studies encompassing neurological and psychiatric disorders, cardiovascular disease, obesity, diabetes, chronic pain and addiction.

studies encompassing neurological and psychiatric disorders, cardiovascular disease, obesity, diabetes, chronic pain and addiction.

At McGill, his laboratory has two main axes of research: 1) Studying interindividual vulnerability to chronic stress and depression and; 2) Understand the role of phenotypically defined subpopulations of

At McGill, his laboratory has two main axes of research: 1) Studying interindividual vulnerability to chronic stress and depression and; 2) Understanding the role of phenotypically defined subpopulations

Join me and learn more about how Kari studies GPCRs in basal ganglia circuits following chronic alcohol

at the University of Bonn, Germany, working initially on the role of prostaglandin receptor EP4 in chronic

characterized the role of RGS4 and RGS5 in airway hyperresponsiveness and lung fibrosis in acute and chronic

has evolved to encompass their roles in regulating immune cell response to acute cardiac injury or chronic

. 🧠 Pain, inflammation, metabolism: the implications go far beyond signaling bias. 🔗 Read the full This could reshape how we understand CGRP-related physiology—and how we target it in drug design. 🧠 Pain

Ian Chronis on the Dr. Ian Chronis In this episode, we welcome Dr. Ian Chronis, a recent Ph.D. graduate preparing to begin his postdoctoral work at the University of Michigan Summary created by AI About Ian Chronis I recently finished my PhD in the lab of Dr. Ian Chronis on the web LinkedIn Enjoying the Dr. GPCR Podcast? Leave a Review.

Home → Flash News → What’s one key piece of advice from Ian Chronis in Ep.164 of the Dr.GPCR Podcast? GPCR Podcast What’s one key piece of advice from Ian Chronis in Ep.164 of the Dr.GPCR Podcast?

GPCR Podcast episode, Ian Chronis shares his top aha moments, from learning the hard way about gel electrophoresis GPCR Podcast episode, Ian Chronis shares his top aha moments, from learning the hard way about gel electrophoresis

Home → Flash News → Can we preserve opioid pain relief without the side effects? GPCR Podcast Can we preserve opioid pain relief without the side effects?

published seminal papers where he used various approaches to describe the role of opioid receptors in pain Dr Gendron is co-director of the FRQS-funded Quebec Pain Research Network and the Editor-in-Chief in

🔬In this episode, Ian Chronis shares his journey from med school dreams to a PhD in pharmacology, diving Ian Chronis #SciencePodcast #GPCR #PhDLife #DrGPCR Published on April 17, 2025 Category Dr. 🔬In this episode, Ian Chronis shares his journey from med school dreams to a PhD in pharmacology, diving Ian Chronis #SciencePodcast #GPCR #PhDLife #DrGPCR Previous Next Recent Articles Why Biotech Fundraising

ADGRC3 are required for the restoration of glutamatergic synapses in prefrontal cortical neurons of chronically

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conjugates to target GPCRs, with a focus on receptors relevant for treating osteoporosis, diabetes, and pain During that time, I investigated the effect of lung cancer-related mutations in the GAIN domain of the

of opioid receptors and is currently focusing on the pharmacology of cannabinoids in the context of pain

characterization of the pharmacological properties of cannabinoids in conjunction with terpenes for pain

Find out in our latest episode featuring Ian Chronis, where we explore the surprising ways GPR65 signals Find out in our latest episode featuring Ian Chronis, where we explore the surprising ways GPR65 signals

conjugates to target GPCRs, with a focus on receptors relevant for treating osteoporosis, diabetes, and pain

next career step took her to AstraZeneca as a postdoctoral trainee, where she studied animal models of pain

neurons), Vollum Institute Portland (visiting scientist with Ed McCleskey, sensory neuron properties); Pain