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We have a catalogue of over 30 fluorescent ligands for different families of GPCRs, including adenosine One of the best tools to study therapeutic targets are fluorescent ligands, which are very useful in Some of the advantages of using fluorescent ligands for this are Lucía from Celtarys Research Sep 23 4 min read Optimizing HTRF Assays with Fluorescent Ligands: Time-Resolved Fluorescence in GPCR Research Product Catalog GPCR Ligands Our GPCR fluorescent ligands are the ideal solution for your High Throughput

Known for their fluorescent ligand innovation, Celtarys is helping researchers make biology visible, Known for their fluorescent ligand innovation, Celtarys is helping researchers make biology visible,

🚀 Dr.GPCR x Celtarys are teaming up to revolutionize fluorescent ligand development for GPCR research Get custom, fast, and functional ligands backed by real scientists solving real assay problems. 🧪 “We 🚀 Dr.GPCR x Celtarys are teaming up to revolutionize fluorescent ligand development for GPCR research Get custom, fast, and functional ligands backed by real scientists solving real assay problems. 🧪 “We

Discover how Celtarys Research is transforming GPCR assay development with fluorescent ligands in this At Celtarys, the focus is on enabling fast, customizable development of fluorescent ligands and chemical ligand development. Their approach is highly consultative—they don’t just sell ligands, they co-develop solutions. GPCR ecosystem , GPCR drug discovery , fluorescent ligands , GPCR scientist network , custom ligand development

GPCR to expand fluorescent ligand tools for GPCR drug discovery, connecting biotech startups and scientists Learn more about new ligands and new GPCR behaviors that produce unique drug profiles. Learn more about new ligands and new GPCR behaviors that produce unique drug profiles. ✳️ Last chance

excited to announce our strategic partnership with Celtarys Research, a biotech company specializing in fluorescent ligand technologies and real-time, non-radioactive GPCR assays. with Celtarys’ innovative chemical biology tools, making it easier than ever for scientists to study ligand-receptor ligand technologies and real-time, non-radioactive GPCR assays. with Celtarys’ innovative chemical biology tools , making it easier than ever for scientists to study ligand-receptor

protein-coupled receptor kinetics, signaling, and trafficking and on using novel imaging techniques, such as fluorescent ligands and complementation methods, to investigate the underlying mechanisms.

Drains Your Biotech’s Runway High-Content Screening for GPCR Programs: Overcoming Assay Limitations with Fluorescent Ligands How a Failed Experiment Created a Powerful GPCR Imaging Tool From Farm Fields to GPCR Discovery

His team develops fluorescence-based and chemically engineered tools to study gpcr internalization and ligand engagement in intact islets and neuronal circuits — insights that inform next-generation functional signaling in metabolic tissues What collaborative chemistry enabled in designing receptor-targeted fluorescent ligands The moment when structural and imaging evidence clarified unexpected glucagon-derived peptide

Got hooked on ligand design. Dr. Maria Majellaro didn’t plan to run a biotech company. Now she’s leading Celtarys, building custom fluorescent probes, and partnering with Dr. Meet Celtarys and learn more about its leading work on ligand-linker-fluorophore chemistry 🚀 ✳️ Listen Got hooked on ligand design. Dr. Maria Majellaro didn’t plan to run a biotech company. Meet Celtarys and learn more about its leading work on ligand-linker-fluorophore chemistry 🚀 ✳️ Listen

Discover pHSense™ portfolio From binding to signaling to internalization: Cell-based fluorescence assays for complete GPCR characterization The principle of pHSense™ relies on the pH-dependent fluorescence Time-Resolved Fluorescence (TRF) = High Signal-to-Background: Europium’s long-lived fluorescence allows comprehensive reagent portfolio to match that complexity—supporting every stage of the signaling pathway, from ligand Ligand binding Measure receptor engagement with high sensitivity using TR-FRET, radioligand, and Fluorescent

Celtarys started with a thesis project, a new chemical strategy, and a vision to make fluorescence available Celtarys began to with a thesis project, a new chemical strategy, and a vision to make fluorescence available

That’s why Celtarys designs custom fluorescent probes for every target, built for real pharmacology, That’s why Celtarys designs custom fluorescent probes for every target, built for real pharmacology,

early discoveries in cyclic AMP signaling to uncovering ultrasensitive receptor responses at femtomolar ligand This conversation is especially valuable for scientists developing functional assays, fluorescence-based The moment when femtomolar ligand concentrations uncovered unexpected receptor sensitivity. . ⸻ Why It Might Hit Home If you’ve ever: Faced unexpected assay behavior at ultra-low ligand concentrations

With a career spanning two decades at the intersection of fluorescence chemistry, functional assays, Originally trained as a physicist with a strong interest in photophysics and fluorescence chemistry,

→ In case you haven’t heard, registrations are open for the next 4-week course “Development of GPCR Ligands Membership 🚀 ✳️Go to https://www.ecosystem.drgpcr.com/event-details-registration/development-of-gpcr-ligands-as-therapeutic-drugs Courses In case you haven’t heard, registrations are open for the next 4-week course “Development of GPCR Ligands Membership 🚀 ✳️Go to https://www.ecosystem.drgpcr.com/event-details-registration/development-of-gpcr-ligands-as-therapeutic-drugs

Terry Kenakin, “Development of GPCR Ligands as Therapeutic Drugs” is coming up 🧐 Be the first to register ✳️Go to https://www.ecosystem.drgpcr.com/event-details-registration/development-of-gpcr-ligands-as-therapeutic-drugs Terry Kenakin, “Development of GPCR Ligands as Therapeutic Drugs” is coming up 🧐 Be the first to register ✳️Go to https://www.ecosystem.drgpcr.com/event-details-registration/development-of-gpcr-ligands-as-therapeutic-drugs

“Development of GPCR Ligands as Therapeutic Drugs” with Dr. Terry Kenakin is here! 👉 https://www.ecosystem.drgpcr.com/event-details-registration/development-of-gpcr-ligands-as-therapeutic-drugs “Development of GPCR Ligands as Therapeutic Drugs” with Dr. Terry Kenakin is here! 👉 https://www.ecosystem.drgpcr.com/event-details-registration/development-of-gpcr-ligands-as-therapeutic-drugs

Home → Flash News → ⏳ In case you haven’t heard—registration for “Development of GPCR Ligands as Therapeutic 👉 Development of GPCR Ligands as Therapeutic Drugs | Dr. GPCR Courses ⏳ In case you haven’t heard—registration for “Development of GPCR Ligands as Therapeutic 👉 Development of GPCR Ligands as Therapeutic Drugs | Dr.

Terry Kenakin for the 4-week course “Development of GPCR Ligands as Therapeutic Drugs”! 👉 https://www.ecosystem.drgpcr.com/event-details-registration/development-of-gpcr-ligands-as-therapeutic-drugs Terry Kenakin for the 4-week course “Development of GPCR Ligands as Therapeutic Drugs”! 👉 https://www.ecosystem.drgpcr.com/event-details-registration/development-of-gpcr-ligands-as-therapeutic-drugs

His current interests include the development of HTS fluorescence-based kinetic binding assays specifically

We have developed an array of fluorescent biosensors to map kinase activity in living cells and are exploring

Home → Flash News → 🎯 Crack the code of GPCR ligand development! In case you haven’t heard, Dr. 👉 Development of GPCR Ligands as Therapeutic Drugs | Dr. GPCR Courses 🎯 Crack the code of GPCR ligand development! In case you haven’t heard, Dr. 👉 Development of GPCR Ligands as Therapeutic Drugs | Dr.

He currently uses high-resolution fluorescence microscopy and biochemistry to study GPCR trafficking

Check out the development of a NanoBRET assay platform to detect intracellular ligands for the chemokine Check out the development of a NanoBRET assay platform to detect intracellular ligands for the chemokine methods-and-updates-in-gpcr-research/development-of-a-nanobret-assay-platform-to-detect-intracellular-ligands-for-the-chemokine-receptors-ccr6

, cannabinoid receptor) and ion channel (K, Ca, TRP channel) function; mostly electrophysiology and fluorescence-based

🚀 Learn the practical issues with detecting, measuring, and quantifying GPCR ligand-biased signaling 🚀 Learn the practical issues with detecting, measuring, and quantifying GPCR ligand-biased signaling

New simulations reveal the conformational changes from inactive to active states to highlighting how ligand New simulations reveal the conformational changes from inactive to active states to highlighting how ligand

In addition, I generated various optical biosensors based on fluorescence or bioluminescence resonance

Then, with Celtarys, the team did the same for ligand-linker-fluorophore chemistry. Then, with Celtarys, the team did the same for ligand-linker-fluorophore chemistry.