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- Signals, pH, and Discovery : Cracking GPCR Mysteries with Dr. Ian Chronis | Dr. GPCR Ecosystem
Throughout the episode, Ian reflects on the value of a supportive lab culture , the need for better experimental About Ian Chronis I recently finished my PhD in the lab of Dr.
- Graciela Pineyro: Resilience, Lab Life, and the Zoom Effect | Dr. GPCR Ecosystem
Graciela Pineyro shares what a forced lab shutdown taught her about prioritization, remote lab meetings Zoom did not flatten the lab. It flattened the hierarchy of who gets heard. The personal cost doesn't stay outside the lab. Dr. Running a lab during the pandemic was rarely just a scientific problem. Lab on Pubmed Dr.
- Silvio Gutkind: Building a Lab That Doesn't Shut Down | Dr. GPCR Ecosystem
Silvio Gutkind on keeping a cancer research lab running at 10% occupancy, why rotation students act like Every lab member needed a contract. Silvio Gutkind on the web Gutkind Lab – UC San Diego Moores Cancer Center Gutkind Lab publications More Publications from the Gutkind Lab on Pubmed Dr. J Silvio Gutkind on LinkedIn Gutkind Lab on Twitter UCSD Moores Cancer Center Dr.
- Dr. John Janetzko | Dr. GPCR Ecosystem
At Harvard, I worked in the labs of Drs. To further develop these ideas, I joined the lab of Dr. He then moved to Dan's lab where he met Suzanne and her project. He chose Brian's lab due to his interest in studying conformational changes. John explained the collaborative culture in Brian's lab, where individuals are encouraged to pursue projects
- Dr. Michael Feigin | Dr. GPCR Ecosystem
Mike then joined the lab of Dr. Feigin, et al., PNAS, 2014) in breast cancer pathogenesis, using mouse models, three-dimensional cell culture David Tuveson at CSHL where he participated in the development of an organoid system for the culture Michael Feigin on the web Roswell Park Feigin Lab Google Scholar LinkedIn Twitter Dr. Next steps • Mike will consider using Twitter to post job positions in his lab.
- Hacking GPCRs: Tools, Tech & Drug Discovery with Tom Sakmar & Ilana Kotliar | Dr. GPCR Ecosystem
Family B GPCRs evolved into a comprehensive resource for the GPCR research community — bridging wet-lab The lab’s early partnership with students like Emily Lorenzen catalyzed a transition from single-receptor This methodology was enhanced through collaboration with Jochen Schwenk’s lab at SciLifeLab in Karolinska Kotliar joined the Sakmar lab as a rotation student and immediately saw the project’s potential. Sakmar reflects on the generational shift in research culture.
- Stuart Maudsley: Receptor Complexity, Aging, and the Limits of Single Target Drugs | Dr. GPCR Ecosystem
About Stuart Maudsley Stuart Maudsley leads the Receptor Biology Lab at the University of Antwerp, where inputs Aging framed as unrepaired damage, with disease as the visible end of a long silent process The culture Data becomes understandable when it becomes an object His lab condenses high dimensional datasets into the discovery of DNA, and the choice of pharmacology 07:29 Writing to Robert Lefkowitz, and what a lab 02:29:13 Advice for young scientists: make the decision, then own it 03:18:29 Work, family, and the culture
- Dr. Thomas P. Sakmar | Dr. GPCR Ecosystem
Khorana’s lab made early key contributions and developed strategies to express, reconstitute and assay Tom’s lab also pioneered the early use of computational homology modeling, molecular dynamics simulations Tom’s lab also developed an amber codon suppression method to genetically encode unnatural amino acids into membrane proteins expressed in mammalian cell culture. Recently, Tom’s lab discovered, along with Yu Chen and Ping Chi , that a mutant of CYSLTR2 is a driver
- Yamina Berchiche: Beyond the Lab — From Chemokine Receptors to the Dr. GPCR Ecosystem | Dr. GPCR Ecosystem
. << Back to podcast list Strategic Partner(s) Yamina Berchiche: Beyond the Lab — From Chemokine Receptors Michel Bouvier's lab on BRET-based conformational readouts. Berchiche didn't get in Michel Bouvier's lab led her to Nikolaus Heveker's newly opened lab at CHU Sainte-Justine After nearly two decades in the lab, Dr. Without that tissue, GPCRs stay siloed by receptor family and by lab.
- Antony Boucard: Adhesion GPCRs and the Molecular Code of Synapse Formation | Dr. GPCR Ecosystem
The foundation of this program rests on a serendipitous discovery Boucard made in Thomas Südhof's lab The Black Widow Toxin Nobody Put Together Working in Südhof's lab on cell adhesion molecules, Boucard drawing students from across Latin America and indigenous communities within Mexico, and a scientific culture Boucard´s lab focuses on molecular and cellular mechanisms underlying the function of adhesion GPCRs Having a particular interest for a three-member family named latrophilins, his lab seeks to decipher
- Dr. Arthur Christopoulos | Dr. GPCR Ecosystem
Additionally, they explored the unique culture and structure of their Institute, highlighting its translational Podcast Format, Team Culture, and Science Yamina and Arthur concluded their discussion and decided to idea of starting a similar talk show format to 'Between Two Ferns', the importance of maintaining team culture universities, including resistance to change and the need to communicate expectations and protect established cultures emphasized the importance of differentiation, impact, and interest in their hiring process and fostering a culture
- Dr. Arthur Christopoulos | Dr. GPCR Ecosystem
Additionally, they explored the unique culture and structure of their Institute, highlighting its translational Podcast Format, Team Culture, and Science Yamina and Arthur concluded their discussion and decided to idea of starting a similar talk show format to 'Between Two Ferns', the importance of maintaining team culture universities, including resistance to change and the need to communicate expectations and protect established cultures emphasized the importance of differentiation, impact, and interest in their hiring process and fostering a culture
- Beatriz Blanco-Redondo: Adhesion GPCR Discovery in Drosophila | Dr. GPCR Ecosystem
decisions in academic science, uncertainty, reentry, and the conditions that keep scientists in the lab describes a period after returning from New York when she was genuinely uncertain about continuing in the lab GPCR University mid-roll 06:17 - Life in New York; comparing research cultures across continents 08:30 Drosophila 13:57 - Naming Remulate, ketchup, and mayo; why Remulate became the primary focus 15:47 - Lab
- Dr. Sai Prasad Pydi | Dr. GPCR Ecosystem
Jurgen Wess’s lab at the National Institute of Diabetes, Digestive and Kidney Diseases (NIDDK) - NIH, His laboratory uses knock-out and transgenic mouse models, along with different cell culture systems,
- Sam Hoare: Receptor Residence Time and GPCR Data Analysis | Dr. GPCR Ecosystem
current work extends that logic into signaling kinetics: the time dimension in GPCR signaling that labs After a PhD on allosteric modulation of dopamine receptors in Philip Strange's UK lab and a postdoc at The tractability of GPCRs as a pharmacological system — assay accessibility, theory, and the generous culture Yet that is precisely how most labs treat time-course signaling data — collecting it, plotting it, and
- Terry Hébert | Dr. GPCR Ecosystem
Terry Hebert on why challenge trials weren't ready, what it takes to hold a GPCR signaling lab together BRET platforms carry work forward when the lab can't. A lab is a social infrastructure, not just a physical one. Reopening is a puzzle about labs, not benches. Lab The GPCR Consortium PubMed Dr.
- Jacob Lee and Jin Cho: Rebuilding the Software Layer Under Modern Research | Dr. GPCR Ecosystem
Jacob Lee and Jin Cho, co-founders of GeneMode, on the ten billion dollars American labs waste every His frustrations as a first-year graduate student navigating inaccessible lab software became the seed Access to the lab's tools is often rationed by seniority. Lab infrastructure is the hidden variable in drug discovery timelines. Private and shared workspaces both matter, even in collaborative labs.
- Arun Shukla: How Two Arrestins Regulate 800 GPCRs | Dr. GPCR Ecosystem
That moment of unplanned utility is a recurring theme in his lab. miss my theory classes to work in the lab. Bob Lefkowitz and asked him if he could join his lab at Duke University. Dr. Shukla spent several years in the Lefkowitz lab and collaborated extensively with Dr. Arun Shukla Lab Google Scholar PubMed Wikipedia LinkedIn Twitter Dr.
- GPCR University Group Package | Dr. GPCR Ecosystem
GPCR Premium access for your entire academic lab. Teach a course at Dr. GPCR Premium — Free for Your Entire Lab Empowering academic discoveries with industry-grade GPCR resources We want to support academic labs with the same high-quality tools, courses, and insights used by leading GPCR Academic Team Access Program gives your entire lab one year of Premium membership at no cost, in Book Ready to Unlock Premium for Your Entire Lab—At No Cost?
- Dr. Daniel Wacker | Dr. GPCR Ecosystem
Daniel Wacker I obtained my B.Sc. degree from the University of Munich performing work in the lab of Roland Beckmann with a brief stay at Cambridge University, UK, working in the lab of the late Dr. I next moved to Rockefeller University in NYC to work in the lab of the late Dr. There I obtained my Ph.D. in the lab of Dr. I then moved to UNC at Chapel Hill to do postdoctoral work in the lab of Dr.
- Randy Hall: Adhesion GPCRs and the Tail Nobody Wanted | Dr. GPCR Ecosystem
Randy Hall arrived in Bob Lefkowitz's lab from a background in ionotropic glutamate receptors, noticed At the time, the lab chasing the first GPCR crystal structure was cutting the tail off entirely. experiment designed to kill receptor signaling that instead amplified it, the tethered agonist model his lab at the Vollum Institute on receptor trafficking and phosphorylation, before joining Bob Lefkowitz's lab Within a few years, dozens of labs were running similar studies across every GPCR subfamily.
- Anything BUT GPCRs with Dr. Mikel Garcia-Marcos | Dr. GPCR Ecosystem
established approaches (biochemistry, cell biology, genetics) and experimental systems (purified proteins, cultured Garcia-Marcos shares insights on transitioning from postdoctoral research to leading his own lab, addressing
- When to Walk, When to Run: Lessons from the GPCR Trenches with Dr. Ben Clements | Dr. GPCR Ecosystem
Mentorship, Team Culture, and the Joy of Science Science is serious work, but Ben believes fun and collaboration At Michigan, his lab balances rigor with light-hearted engagement — like daily squirrel trivia on their Still, by collaborating with structural biology teams and combining cryo-EM with NMR , his lab is narrowing
- Dr. Demet Araç | Dr. GPCR Ecosystem
Axel Brunger’s lab at Stanford University to study the structure and function of cell-adhesion proteins They also acknowledged the cultural differences between Demet's home country, Turkey, and Yamina's, Canada He explained that initially, the field lacked adequate tools, and his lab had to develop new techniques
- Why Mosquitoes Hunt You: GPCR Control of Blood Feeding and Mating | Dr. GPCR Ecosystem
Laura Duvall's lab has traced this suppression to a specific neuropeptide Y family receptor, one she About Laura Duvall runs a research lab in the Department of Biological Sciences at Columbia University When the lab went looking for where this NPY family receptor was expressed, they assumed brain tissue Work on neuropod and enterochromaffin cells in mammals has become a guide for what Duvall's lab looks user=Vk3KGSoAAAAJ&hl=en - Lab: https://www.duvalllab.com/ Unlock the Full Dr.
- Dr. JoAnn Trejo | Dr. GPCR Ecosystem
biology, acquired critical expertise, and rigorous approaches to examine PAR1 function using human cultured JoAnn Trejo on the web UC San Diego Trejo Lab Wikipedia LinkedIn Google Scholar Orcid Twitter UC San
- Bryan Roth: Inside the DARPA Bet on a Non-Psychedelic Psychedelic | Dr. GPCR Ecosystem
His lab works on serotonin, dopamine, and opioid receptor structure, function, and drug discovery, with Roth's lab identified salvinorin A as a kappa opioid receptor agonist. A reminder of what scientific certainty sometimes looks like outside the lab. The arc from a lab "about as big as your car" at Case Western to leading a thirty-person GPCR lab at Bryan Roth on the web UNC School of Medicine / Pharmacology Roth Lab Roth Leads $26.9 Million Project
- Michel Bouvier: BRET, Biased Agonism, and the Tools That Changed GPCR Pharmacology | Dr. GPCR Ecosystem
reticulum, to the experimental frameworks that made biased agonism a credible drug discovery target - his lab personal loss that drew Bouvier toward the sympathetic nervous system, the postdoc in Bob Lefkowitz's lab biology revolution in GPCR science, and the foundational question that has guided every receptor his lab Every receptor his lab has studied was selected because it was the right model for a question that was developed in his lab to better understand GPCR structure/function relationships.
- Paul Insel: Rethinking COVID-19 Pathobiology Through GPCR Signaling | Dr. GPCR Ecosystem
When his lab closed in 2020, Dr. Paul Insel turned dry-lab science into a reframing of COVID-19 pathobiology as a GPCR signaling imbalance Paul Insel did something unusual for a working lab scientist: he stopped pipetting, and started writing and PAR4 antagonists The "gas pedals and brakes" philosophy of cell signaling and pharmacology Dry-lab It is exactly the kind of work a pharmacologist does when the lab is closed.
- Gunnar Schulte: Frizzled Receptors and the GPCR Identity Question | Dr. GPCR Ecosystem
Gunnar Schulte's lab at Karolinska Institute has spent years assembling the evidence on the other side not just a technical inconvenience — it is the central obstacle that has shaped every decision his lab His lab investigates the molecular mechanisms of frizzled receptor activation, including G-protein coupling GPCR identity Using cpGFP-based conformational sensors inserted into frizzled receptors, Schulte's lab Gunnar Schulte on the web Schulte Lab LinkedIn Google Scholar Orcid YouTube Dr.






























